Category: Education

  • MIL-OSI USA: Reed, Environmental Leaders Tout Importance of BEACH Grant Clean Water Monitoring Program

    US Senate News:

    Source: United States Senator for Rhode Island Jack Reed

    As Trump seeks to eliminate BEACH grants and cut funding to stop sewage overflows and runoff pollution, Reed seeks to keep clean water monitoring system afloat and restore clean water funding investments

    WASHINGTON, DC – As more people head to coastal beaches, Great Lakes, and local waterways to enjoy the summer weather, U.S. Senator Jack Reed (D-RI) is leading federal efforts to help ensure America’s swimming beaches remain clean, safe, and welcoming to the public and protect human health, environmental health, and the economic health of coastal communities. 

    Today, outside the U.S. Capitol, Senator Reed joined Environment America, NCAA athletes who train in open waters, public health advocates, and fellow members of Congress to discuss the importance of the Beaches Environmental Assessment and Coastal Health (BEACH) Act grant program to help monitor beach water quality nationwide. VIDEO AVAILABLE.

    Federal BEACH grants support beach water-quality collection, testing, and monitoring and public notification efforts if bacteria levels become unsafe.

    “The BEACH Act is a smart investment in protecting public health, economic health, and the health of our waterways.  It ensures people are informed when temporary beach closures are warranted and provides policymakers with the data needed to ensure sound management,” said Senator Reed, a member of the Appropriations Subcommittee on Interior and Environment, which oversees federal BEACH Act funding.  Reed and his fellow appropriators helped make $9.7 million in BEACH grant funding for water quality monitoring at coastal and Great Lakes beaches in 2025 and he and several colleagues requested at least $15 million for BEACH grants in Fiscal Year 2026.  “Clean, safe beaches are an economic and environmental imperative.  I oppose President Trump’s attempt to eliminate BEACH grants and clean water infrastructure funds.  Fixing and updating water systems isn’t cheap or easy.  But it’s absolutely essential to public health, environmental health, and America’s economic well-being.”

    “There’s nothing better than running into the water with your friends and family on a hot day in summer, but too often, our favorite beaches aren’t safe for swimming,” said Lisa Frank, executive director of Environment America, a non-profit that recently released its annual Safe for Swimming? report on the water quality of America’s beaches. “Keeping sewage pollution out of our waterways isn’t rocket science, but it’s clear more investment is needed to protect our health.”

    “Growing up on the shores of Lake Erie, I’ve always had a deep appreciation for our beaches. These natural wonders are invaluable sources of recreation and economic drivers for our communities, but pollution and contamination threaten to make them too dangerous for the public,” said U.S. Representative Dave Joyce (R-OH). “I urge Congress to swiftly pass the BEACH Act, which will ensure that our beaches and the surrounding waters remain safe for future generations.”

    “As a Division-1 rower, being able to train on a waterway without fear of exposure to nasty bacteria is vital to my well-being,” said Jordan Stock, a student athlete at Stanford University. “I should not have to risk my health to practice the sport that I love. From competitive water athletes like myself, to the local businesses sustained by beach tourism and clean water, to casual swimmers, surfers and sailors, this issue affects everyone.” 

    Common issues that make waterways unsafe include sewer overflows and runoff pollution.  Swimming in waters contaminated with elevated levels of enterococci bacteria can cause gastrointestinal illness, according to the U.S. Environmental Protection Agency (EPA), which administers BEACH grants to coastal and Great Lake states based on a formula that includes the length of the recipients’ beach season, number of miles of shoreline, and population. Recipients must also have an EPA- approved water quality standards program.

    Researchers estimate that people get sick 57 million times a year from swimming in polluted waters and Environment America released a new study showing nearly two-thirds of U.S. beaches (1,930 out of 3,187) experienced fecal contamination at some point last year, with roughly 1 in 7 beaches — 453 of those sampled — experiencing potentially unsafe fecal contamination on at least 25 percent of the days on which testing occurred.

    Since Senator Reed helped launch the BEACH Act in 2001, over $225 million in BEACH grants have been awarded to test beach waters for illness-causing bacteria, identify the sources of pollution problems, and help notify the public.  This year’s continuing resolution appropriated nearly $10 million in BEACH Act funds, resulting in $210,000 for Rhode Island.  But now, the Trump Administration is trying to eliminate the program.

    Nationwide, Gulf Coast beaches experienced the biggest share of unsafe water quality days in 2024 — 84 percent of Gulf Coast beaches experienced at least one unsafe swimming day — while just 10 percent of Alaska and Hawaii’s beaches had an unsafe day.

    Rhode Island’s coastal beach-water quality monitoring program is managed by the Rhode Island Department of Health and works closely with the state’s Department of Environmental Management (DEM), cities, towns, and volunteer groups.

    MIL OSI USA News

  • MIL-Evening Report: Is childbirth really safer for women and babies in private hospitals?

    Source: The Conversation (Au and NZ) – By Hannah Dahlen, Professor of Midwifery, Associate Dean Research and HDR, Midwifery Discipline Leader, Western Sydney University

    A study published this week in the international obstetrics and gynaecology journal BJOG has raised concerns among women due to give birth in Australia’s public hospitals.

    The study compared the outcomes of mothers and babies, as well as the costs, of standard public maternity care versus private obstetric-led care from 2016 to 2019 in Victoria, New South Wales and Queensland.

    It found women who gave birth in the public system were more likely to haemorrhage, sustain a third or fourth degree tear, and were less likely to have a caesarean than those who birthed in the private system. It found their babies were more likely to be deprived of oxygen, to be admitted to intensive care and to die.

    But the study and subsequent media reports don’t tell the whole story. There are also several reasons to be cautious about this data.

    And it’s important to keep in mind that while things sometimes go wrong during childbirth, the majority of women who give birth in Australia do so safely.

    Birth options in Australia

    Australia has a two-tiered system of health care:

    • a publicly funded system that provides care for free, or limited out-of-pocket costs, to patients in public hospitals

    • a private system where patients with private health insurance access care from doctors mainly in private hospitals. They face varying out-of-pocket costs.

    There are multiple models of maternity care in Australia, but these can be grouped into:

    • fragmented care models, where women see many different care providers. Fragmented models include medical and midwifery care, and GP shared care (shared between GPs, obstetricians and midwives)

    • continuity of care models where one (or a small number of providers) provide the majority of the care throughout the antenatal, birth and postnatal period. This includes continuity of midwifery care in the public system, private obstetric care, or care from a privately practising midwife in the private system.

    Women favour continuity of care and they and their babies experience better outcomes in these models, especially under midwifery continuity of care.

    However, continuity of midwifery care can be difficult to access, despite calls to expand this model worldwide.

    Digging into the data

    The BJOG paper examined the outcomes for 368,292 births selected out of a bigger data set of 867,334 women who gave birth in NSW, Queensland and Victoria between January 2016 and December 2019.

    It used publicly available data collected on each birth in three states in Australia, as well as Pharmaceutical Benefits Scheme (PBS) and Medicare Benefits Schedule (MBS) data linked to these cases to help examine cost.

    The study grouped all the models of care together in the public system and compared them to one model of private obstetric care (excluding the privately practising midwifery model altogether).

    A major problem with doing research with big data sets is they do not contain the many medical and social complexities that inform health outcomes. These complexities are much more prevalent in the public system and impact on health outcomes.

    Only diabetes and blood pressure problems were included in medical complications controlled for in this paper.

    But there are others that impact on outcomes. There was no controlling for drug and alcohol use, mental health, refugee status and many more significant factors impacting health outcomes for mothers and babies.

    On the other hand, women who give birth in private hospitals are more likely to be socially advantaged (with higher incomes, more education, and greater access to health care, transport and safe housing), which also impacts on birth outcomes.

    While the researchers attempted to “match” the population groups to be as similar as possible and reduce these differences, some of the variables were not included in the data sets. Data on artificial reproductive technology, body mass index and smoking, for example, were not available in all three states. These variables impact outcomes.

    The study did not consider some key outcomes often used to measure maternity care, such as rates of episiotomies (surgical cuts to the perineum). Rates of episiotomies are higher in the private sector.

    The findings of the study also differ from other research on some measurements, such as third and fourth degree perineal tears. The BJOG paper reports severe perineal tearing is lower in private hospitals, while other earlier research shows the opposite.

    Severe perineal tearing does, however, occur more often among some ethnic groups who are more likely to have public health care.

    More c-sections

    The study found women in private hospitals were more likely to have a caesarean section (47.9%) than in the public system (31.6%). There were also higher rates of caesarean sections undertaken before 39 weeks in private obstetric-led care.

    It was beyond the scope of the paper to examine the impacts of this on children, however previous research shows early births are linked to an increased risk of developmental problems, such as poorer school performance.

    While caesarean sections are generally safe, past research as found c-sections can increase risks for women’s future pregnancies and births and can have long-term impacts on children’s health.

    Our previous research showed low-risk women who gave birth in private hospitals had higher rates of intervention but earlier research showed no difference in the rate of deaths. Thankfully, baby deaths are very rare in Australia’s high-quality health system.

    It’s important that women have a choice in how they give birth, and for that choice to be informed and supported. Australian women can also be reassured that Australia is one of the safest countries in which to give birth.

    Hannah Dahlen receives funding from National Health and Medical Research Council, the Australian Research Council, and the Medical Research Future Fund. She is a member of the Australian College of Midwives.

    Jenny Gamble receives funding from National Health and Medical Research Council. She is a member of the Australian College of Midwives. She is a co-author of the BJOG study.

    ref. Is childbirth really safer for women and babies in private hospitals? – https://theconversation.com/is-childbirth-really-safer-for-women-and-babies-in-private-hospitals-261179

    MIL OSI AnalysisEveningReport.nz

  • MIL-Evening Report: What does Australian law have to say about sovereign citizens and ‘pseudolaw’?

    Source: The Conversation (Au and NZ) – By Madeleine Perrett, PhD Candidate in Law, University of Adelaide

    Armed with obscure legal jargon and fringe interpretations of the law, “sovereign citizens” are continuing to test the limits of the Australian justice system’s patience and power.

    A few weeks ago, two Western Australians were jailed for 30 days after defying a Supreme Court order and refusing to acknowledge the court’s authority.

    Weeks earlier, former AFL footballer Warren Tredrea told the Federal Court he could not pay his legal costs to his former employer, Channel 9, because he did not believe in Australian legal tender.

    And former One Nation senator Rod Culleton is currently fighting the Australian Federal Police, arguing his court-declared bankruptcy is not legally binding and therefore should not affect his federal election nomination.

    These are not isolated incidents. They are part of a growing trend known as “pseudolaw”.

    What is ‘pseudolaw’?

    Pseudolaw describes the practice of constructing legal arguments that sound convincing but are fundamentally wrong.

    It often relies on real law or cases, twisting them through bizarre or inaccurate interpretations. It looks like law, but isn’t.

    Common pseudolegal arguments include:

    • governments have no authority over “natural persons”
    • writing a legal name in all capital letters creates a separate legal entity (a “strawman”), which is not subject to state authority
    • money is not real and anything can be legal tender
    • tax laws only apply to federal entities, not individuals
    • “natural rights” override statutes and court-made rules.

    Not one of these arguments has ever succeeded in an Australian court.

    What are ‘sovereign citizens’?

    Those who believe and engage in pseudolaw are sometimes termed “sovereign citizens” or “SovCits”, a label imported from the United States during the 1970s.

    The sovereign citizen “movement” reached Australia in the late 1990s.

    As the Australian Federal Police explain, sovereign citizens believe they are morally and legally correct, and are quite open about their beliefs and plans.

    They reject government authority, refuse to comply with laws and rely on complex but false legal theories to justify their actions.

    Because many social media platforms ban their content, sovereign citizens frequently communicate through encrypted messaging apps or gather in person at protests and “common law courts” – unofficial tribunals based on a distorted reading of historical legal principles. These “courts” claim to operate outside state authority and often “try” public officials, file false claims against property and carry out other pseudolegal actions with no real legal force.

    They claim to be peaceful and say they are acting in “self-defence” against perceived government overreach. But a small number turn violent.

    The rise of pseudolaw in Australia

    In the 1970s, WA farmer Leonard Casley labelled his farm the “Hutt River Province”, then attempted to secede from the Commonwealth of Australia and the State of Western Australia.

    A curiosity back then, but a warning sign.

    For years, fringe tax protesters and anti-government groups quietly pushed these ideas.

    Then the COVID pandemic hit: lockdowns, mandates and rising distrust meant pseudolaw went more viral. Social media lit up with people claiming they weren’t subject to Australian law.

    They spouted strawman theories, cited fake laws and filmed themselves refusing police orders.

    Now it’s in the courts, on the streets and in online echo chambers.

    It is not just noise. It is congesting the judicial system and putting people, including adherents, at risk.

    A recent South Australian study highlights how pseudolaw is increasingly disrupting legal processes in that state.

    The law, however, still stands, no matter what those on YouTube say.

    What the ‘real’ law says

    To be clear, pseudolaw looks real but isn’t; the real law is clear on many of the points raised by sovereign citizens.

    For example, the federal government derives its authority to govern from the Commonwealth Constitution. This document clearly states the government has executive authority and can make laws that bind all Australians.

    This includes tax laws and laws declaring Australian money as legal tender: in 2007, the Federal Court flatly rejected arguments that income tax and currency laws were invalid.

    The “strawman theory” – which states someone has two personas, one of real flesh and blood and the other a separate legal personality, who is the “strawman” – has also been debunked by the courts countless times. The West Australian Supreme Court recently called it “fundamentally misguided”.

    And does capitalising your name on official documents like your birth certificate or driver’s licence affect your rights? The courts have categorically said “no”.

    Pseudolaw is, as one Victorian judge described it last year, nothing more than “nonsense”, “gibberish”, and “gobbledygook”.

    Why sovereign citizens are a threat

    While this might seem eccentric, or even harmless, pseudolaw poses real risks.

    The Judicial Commission of New South Wales warns it’s not just a nuisance – it’s clogging up courts, wasting police resources and putting public officials at risk.

    But the danger isn’t only to others – it is to the followers too.

    Adherents lose more than arguments. Some have racked up massive legal bills fighting fines. Others have lost custody in family court or been imprisoned for ignoring court orders.

    Pseudolaw is a dangerous ideology.

    It is crucial all Australians recognise that pseudolaw not only threatens your credibility but can land you in hot water under the real law.

    The authors do not work for, consult, own shares in or receive funding from any company or organisation that would benefit from this article, and have disclosed no relevant affiliations beyond their academic appointment.

    ref. What does Australian law have to say about sovereign citizens and ‘pseudolaw’? – https://theconversation.com/what-does-australian-law-have-to-say-about-sovereign-citizens-and-pseudolaw-260289

    MIL OSI AnalysisEveningReport.nz

  • MIL-Evening Report: Is it okay to boil water more than once, or should you empty the kettle every time?

    Source: The Conversation (Au and NZ) – By Faisal Hai, Professor and Head of School of Civil, Mining, Environmental and Architectural Engineering, University of Wollongong

    Avocado_studio/Shutterstock

    The kettle is a household staple practically everywhere – how else would we make our hot drinks?

    But is it okay to re-boil water that’s already in the kettle from last time? While bringing water to a boil disinfects it, you may have heard that boiling water more than once will somehow make the water harmful and therefore you should empty the kettle each time.

    Such claims are often accompanied by the argument that re-boiled water leads to the accumulation of allegedly hazardous substances including metals such as arsenic, or salts such as nitrates and fluoride.

    This isn’t true. To understand why, let’s look at what is in our tap water and what really happens when we boil it.

    What’s in our tap water?

    Let’s take the example of tap water supplied by Sydney Water, Australia’s largest water utility which supplies water to Sydney, the Blue Mountains and the Illawarra region.

    From the publicly available data for the January to March 2025 quarter for the Illawarra region, these were the average water quality results:

    • pH was slightly alkaline
    • total dissolved solids were low enough to avoid causing scaling in pipes or appliances
    • fluoride content was appropriate to improve dental health, and
    • it was “soft” water with a total hardness value below 40mg of calcium carbonate per litre.

    The water contained trace amounts of metals such as iron and lead, low enough magnesium levels that it can’t be tasted, and sodium levels substantially lower than those in popular soft drinks.

    These and all other monitored quality parameters were well within the Australian Drinking Water Guidelines during that period. If you were to make tea with this water, re-boiling would not cause a health problem. Here’s why.

    It’s difficult to concentrate such low levels of chemicals

    To concentrate substances in the water, you’d need to evaporate some of the liquid while the chemicals stay behind. Water evaporates at any temperature, but the vast majority of evaporation happens at the boiling point – when water turns into steam.

    During boiling, some volatile organic compounds might escape into the air, but the amount of the inorganic compounds (such as metals and salts) remains unchanged.

    While the concentration of inorganic compounds might increase as drinking water evaporates when boiled, evidence shows it doesn’t happen to such an extent that it would be hazardous.

    Let’s say you boil one litre of tap water in a kettle in the morning, and your tap water has a fluoride content of 1mg per litre, which is within the limits of Australian guidelines.

    You make a cup of tea taking 200ml of the boiled water. You then make another cup of tea in the afternoon by re-boiling the remaining water.

    On both occasions, if heating was stopped soon after boiling started, the loss of water by evaporation would be small, and the fluoride content in each cup of tea would be similar.

    But let’s assume that when making the second cup, you let the water keep boiling until 100ml of what’s in the kettle evaporates. Even then, the amount of fluoride you would consume with the second cup (0.23mg) would not be significantly higher than the fluoride you consumed with the first cup of tea (0.20mg).

    The same applies to any other minerals or organics the supplied water may have contained. Let’s take lead: the water supplied in the Illawarra region as mentioned above, had a lead concentration of less than 0.0001mg per litre. To reach an unsafe lead concentration (0.01mg per litre, according to Australian guidelines) in a cup of water, you’d need to boil down roughly 20 litres of tap water to just that cup of 200ml.

    Practically that is unlikely to happen – most electric kettles are designed to boil briefly before automatically shutting off. As long as the water you’re using is within the guidelines for drinking water, you can’t really concentrate it to harmful levels within your kettle.

    But what about taste?

    Whether re-boiled water actually affects the taste of your drinks will depend entirely on the specifics of your local water supply and your personal preferences.

    The slight change in mineral concentration, or the loss of dissolved oxygen from water during boiling may affect the taste for some people – although there are a lot of other factors that contribute to the taste of your tap water.

    The bottom line is that as long as the water in your kettle was originally compliant with guidelines for safe drinking water, it will remain safe and potable even after repeated boiling.

    Faisal Hai does not work for, consult, own shares in or receive funding from any company or organisation that would benefit from this article, and has disclosed no relevant affiliations beyond their academic appointment.

    ref. Is it okay to boil water more than once, or should you empty the kettle every time? – https://theconversation.com/is-it-okay-to-boil-water-more-than-once-or-should-you-empty-the-kettle-every-time-260293

    MIL OSI AnalysisEveningReport.nz

  • MIL-OSI New Zealand: Surge in NCEA numeracy & literacy results

    Source: New Zealand Government

    Thousands more high school students are passing the foundational literacy and numeracy assessments required for NCEA, clear evidence the Government’s relentless focus on the basics is delivering results, Education Minister Erica Stanford says.

    “The latest NCEA co-requisite assessment results show a marked improvement in student achievement in numeracy and reading, especially in Year 10 for those sitting the assessments for the first time. The Government’s $2.2 million investment in 2024 to provide targeted support to students in 141 lower decile schools has resulted in more students achieving assessments,” Ms Stanford says.

    • Numeracy:
      • 57 per cent of students achieved the standard across all year levels – up from 45 per cent in May 2024.
      • 68 per cent of Year 10 students passed the numeracy assessment, 95 per cent of whom were sitting it for the first time.
      • 34 per cent of students in lower decile schools passed the numeracy assessment in May 2025 compared to 19.8 per cent in May 2024.
    • Reading:
      • 61 per cent of students achieved the standard across all year levels – up from 58 per cent in May 2024.
      • 72 per cent of Year 10 students passed the reading assessment, over 95 per cent of were first time participants.
      • 41 per cent of students in lower decile schools passed the reading assessment in May 2025 compared to 34 per cent in May 2024.
    • Writing:
      • 55 per cent of students achieved the standard across all year levels – holding steady from May last year.
      • 66 per cent of Year 10 students passed the writing assessment, 95 per cent of whom were sitting it for the first time.
      • 35 per cent of students in lower decile schools passed the reading assessment in compared to 34 per cent in May 2024.

    More than half of this year’s Year 12 students who did not meet the co-requisite while in Year 11 last year have now achieved it — and around a third of these students will now be awarded NCEA Level 1. This takes the pass rate for NCEA level 1 in 2024 from 71.5 per cent to 79.6 per cent.

    “These early improvements are the result of a comprehensive reform package focused on lifting academic achievement. We have introduced a new year-by-year, knowledge-rich and internationally benchmarked English and maths curriculum, restored a focus on structured literacy and structured maths, and provided schools with hundreds of thousands of high-quality resources — including over 830,000 maths textbooks, workbooks and teacher guides. 

    “We’re investing significantly in teacher professional development, mandated an hour a day of reading, writing and maths and banned the use of cell phones in schools to ensure every student gets the focused instruction they deserve.

    “While these results are positive, there are still too many students who don’t have the fundamental literacy and numeracy skills they need to thrive. That’s why this Government is unapologetically reforming the education system to prioritise improving student outcomes. As our back-to-basics approach beds in, more children will be better equipped when taking these assessments in the future,” Ms Stanford says.

    MIL OSI New Zealand News

  • MIL-OSI New Zealand: Government calls time on open-plan classrooms

    Source: New Zealand Government

    The Government has put an end to building open-plan classrooms, ensuring all new classrooms are designed in a flexible way to ensure better student outcomes. 

    “Overwhelming feedback I’ve received from schools across New Zealand is open-plan classrooms aren’t meeting the needs of students. While open-plan designs were originally intended to foster collaboration, they have often created challenges for schools, particularly around noise and managing student behaviour,” Education Minister Erica Stanford says.

    “This Government is focused on raising achievement and closing the equity gap and an important part of our reform package is ensuring learning spaces are designed to improve student outcomes.

    “In many cases, open-plan classrooms reduce flexibility, rather than enhance it. We have listened to the sector and new classrooms will no longer be open plan.” 

    The Government has not designed and built open plan classes since being in office other than classrooms that have been specifically requested.

    All new classrooms will be built using standard designs that prioritise flexibility over open-plan layouts. For example, the use of glass sliding doors mean spaces can be open when classes collaborate but can also close for focused learning. This approach ensures schools have fit-for-purpose environments that support a range of teaching and learning styles.

    “We are ensuring school property delivery is efficient and sustainable. We’ve lowered the average cost of a classroom by 28 per cent so we could deliver 30 per cent more classrooms last year compared to 2023. We’re continuing to drive down costs so more Kiwi kids can access them, faster. In 2025, new classrooms cost on average $620,000 compared to $1.2 million at the end of 2023.”

    Wellington is the latest region to benefit from this, with a $25 million targeted investment into areas experiencing population growth.

    The schools receiving new classrooms are:

    Newlands Intermediate – 10 classrooms
    Aotea College – 16 classrooms

    “Aotea College is a prime example where existing open-plan classrooms did not support learning outcomes. The lack of functionality of the open design meant spaces could not be shared or multipurpose due to disruption and noise. This investment will deliver new, standard teaching spaces that better meet the needs of both students and staff.

    “Delivering these classrooms through repeatable designs and offsite-manufactured buildings also ensures we are achieving maximum value for money. Planning is already underway for these projects, with construction expected to begin within the next 12 months,” Ms Stanford says.

    MIL OSI New Zealand News

  • MIL-OSI New Zealand: Parents to know more about child’s school progress

    Source: New Zealand Government

    Parents will know more about how their children are doing at school with the confirmation of a new assessment tool in Years 3-10 classrooms from 2026, the latest part of the Government’s plan to teach the basics brilliantly.

    Janison Solution Pty Ltd will deliver the Student, Monitoring, Assessment and Report Tool (SMART) which will enable twice-yearly assessment of reading, writing and maths in schools nationwide.

    “Last year the Auditor General found there was no consistent and comprehensive summary of student achievement and progress in New Zealand, and what information the Ministry of Education had was more detailed for some students than for others. This new tool changes that,” Education Minister Erica Stanford says.

    “The check-ins will be low stakes measures of student progress and provide teachers with information on next steps in learning. They’ll give parents confidence as to how their children are progressing so they can support learning at home. It will also provide crucial information to the Government to know where to invest more resource to help accelerate learning.” 

    SMART will be modern, flexible and curriculum aligned. It will also be bilingual to cover pānui, tuhituhi and pāngarau in kura. Years 9 and 10 have been included so parents and teachers know how ready students are for NCEA.

    “This builds on our new suite of classroom tools that help parents and teachers understand more about student progress. The Phonics Checks undertaken at 20 weeks of schooling and repeated at 40 weeks identifies a child’s reading ability early and wrap around support if needed. A similar approach is being taken with maths, from 2026 every child will have their maths ability checked in Year 2. 

    “I am committed to helping parents clearly understand their child’s progress at school, because when parents are informed and involved, students are more likely to reach their full potential,” Ms Stanford says. 

    MIL OSI New Zealand News

  • MIL-OSI Australia: New Regional University Study Hub opens on King Island

    Source: Murray Darling Basin Authority

    A new Regional University Study Hub officially opened today on King Island, bringing university closer for local residents.

    Nearly half of young people in Australia have a degree but not in regional and remote Australia. On King Island, only around 22 per cent of young people have a degree.

    The evidence shows that where Regional University Study Hubs are, university participation goes up.

    This new Study Hub, co-located in the new King Island Community Hub, will provide support and facilities for students who are studying a university or VET course without having to leave their community.

    Study King Island is part of the Albanese Government’s $66.9 million investment to more than double the number of University Study Hubs across the country.

    The hub is operated by West Coast Heritage who operate the existing Study Hub West Coast with sites in Smithton and Zeehan, which has supported over 330 students since opening. 

    This is one of the ways the Albanese Labor Government is helping more people get a crack at going to TAFE or university, including:

    • cutting 20 per cent off of all student loans, wiping around $16 billion in student debt for three million Australians
    • fixing the indexation formula and wiping a further $3 billion in student debt, combined this will cut close to $20 billion in student debt
    • introducing a Commonwealth prac payment for teaching, nursing, midwifery and social work students
    • making free TAFE permanent.

    For more information: Regional University Study Hubs – Department of Education, Australian Government

    Quotes attributable to Minister for Education Jason Clare:

    “Today, almost one in two young people have a university degree. But not everywhere. Not in the outer suburbs and not in regional Australia, or communities like King Island.

    “In the years ahead more jobs will require more skills.

    “The Government has set a target that by 2050, 80 per cent of workers will have a TAFE or university qualification.

    “To hit that target we have to break down that invisible barrier that stops a lot of people from the bush getting a crack at going to university.

    “The evidence is that where Study Hubs are, university participation goes up. That’s why we are doubling the number of Hubs across the country.”

    Quotes attributable to Member for Braddon, Anne Urquhart:

    “Study King Island will offer both young and mature local students the opportunity to have a dedicated study hub with support on the Island and help raise education aspirations.

    “The Hub will provide support to local students studying at any Australian University or VET provider, allowing students to stay on Island and remain near their support networks while completing their studies.”

    MIL OSI News

  • MIL-OSI USA: McClellan Introduces Resolution on Extreme Weather’s Threat to Children’s Health and Well-Being

    Source: United States House of Representatives – Congresswoman Jennifer McClellan (Virginia 4th District)

    Washington, D.C. – Today, Congresswoman Jennifer McClellan (VA-04) led 32 of her colleagues to introduce a resolution calling on Congress to acknowledge and address the threat extreme weather poses to children’s health and well-being.

    H.Res. 585 urges Congress to develop solutions that account for children’s unique developmental vulnerabilities as they relate to extreme weather conditions and highlights enforceable and adaptive measures, such as timely and accessible public extreme weather alerts; education and training for health care professionals, educators and caregivers; and expanded access to safe places for children and families during extreme weather events. 

    “Just in the past month, extreme weather events have utterly devastated communities across the country — and we know that climate change only accelerates the frequency and intensity of these events,” said Congresswoman McClellan. “As a mother, I am fighting to advance climate and environmental policies that ensure a safe, habitable planet for our children and future generations to thrive. My resolution calls on Congress to implement solutions to comprehensively protect the health and well-being of our nation’s children, who have the most at stake in the decisions we make today.”

    The resolution lays out specific impacts of extreme weather on child and adolescent health, including: 

    • Children’s disproportionate exposure to pollutants in the air, increasing levels of wildfire smoke, and changing dust patterns that negatively impact children’s developing bodies and behavioral patterns;
    • Extreme heat’s link to impairment in children’s cognition, making it harder for them to learn at school, and an increase in schools across the country closing for heat days, disrupting academic performance; and
    • The disproportionate impact of life-altering trauma due to extreme weather disasters, including separation from or harm to caregivers, interruption in education, and other adverse mental health impacts that exacerbate the mental health crisis children and adolescents already face.

    McClellan’s resolution is endorsed by Moms Clean Air Force, Alliance of Nurses for Healthy Environments, American Association of Children and Adolescent Psychiatry, American Heart Association, American Lung Association, American Medical Informatics Association, American Public Health Association, Association of Community Health Nursing Educators, Association of Public Health Nurses, Children & Nature Network, Children’s Environmental Health Network, Climate Mental Health Network, Climate Psychiatry Alliance, Climate Psychology Alliance, Council of Public Health Nursing Organizations, ecoAmerica, Environmental Defense Fund, First Focus on Children, Green Schoolyards America, Mothers Out Front, National Association of Pediatric Nurse Practitioners, National League for Nursing, OneGreenThing, Physicians for Social Responsibility, Sierra Club, Society of Behavioral Medicine, Trust for America’s Health, Virginia Clinicians for Climate Action, and ZERO TO THREE. 

    “Extreme weather events, supercharged by climate pollution, are going to become more frequent, more intense —and more dangerous,” said Dominique Browning, Founder of Moms Clean Air Force. “We are indebted to Representative McClellan for her leadership in protecting our children. With the weather on steroids, we must consider children’s unique vulnerabilities as we create and fund adaptations. Moms Clean Air Force will continue our fight against climate and air pollution. But we must also adapt to the damaging effects now baked into our weather systems, so we can keep our children safe.”

    Read the full resolution text here

     

    MIL OSI USA News

  • MIL-OSI China: China’s supply chain expo highlights global push for cooperation, openness

    Source: People’s Republic of China – State Council News

    BEIJING, July 16 — As the third China International Supply Chain Expo (CISCE) opened in Beijing on Wednesday, global business executives and officials voiced a collective need to reinforce supply chains through open markets, innovation, and multilateral engagement.

    “This event is much more than an expo. It is a forest of connections between economies, industries, and people,” John Denton, the secretary-general of the International Chamber of Commerce, said in his speech. “We are here together to advance our shared prosperity.”

    Denton’s remarks echoed a widespread consensus among attendees that building trust and deeper integration — spanning AI innovation to global manufacturing collaboration — is essential for effectively navigating the increasing global uncertainties.

    Held from July 16 to 20, the 2025 CISCE gathered more than 650 companies and institutions from 75 countries, regions and international organizations, along with over 500 of their upstream and downstream partners.

    Foreign exhibitors made up 35 percent of the total participation — an indicator of enduring business interest in the face of rising geopolitical and economic headwinds.

    Hosted by the China Council for the Promotion of International Trade (CCPIT), the expo is the world’s first national-level expo dedicated exclusively to supply chains.

    In the lead-up to the event, Wang Yiwei, director of the Institute of International Affairs at Renmin University of China, said that active engagement from multinational firms reflects the “continued momentum and irreversibility of globalization.”

    Wang noted that China, with the world’s most complete and largest industrial system, is playing a growing role in driving global development through digital and green transformation — and is increasingly seen as an innovation lab.

    China’s expanding role in global innovation ecosystems, especially in AI, was underscored by Nvidia CEO Jensen Huang, who delivered a speech during his first CISCE appearance.

    Calling China’s supply chain “a miracle,” Huang highlighted the country’s fast-growing AI technologies and its global reach. “China’s open-source AI is a catalyst for global progress,” he said, as it enables broader access to innovation and supports international cooperation on standards and safeguards.

    In an interview on the sidelines of the expo, Huang reaffirmed Nvidia’s long-term commitment to the Chinese market. “If you want to maintain, you have to invest,” he said. “The market is moving so fast and it’s so competitive — we have to continue to advance ourselves.”

    He added that China’s technology market is growing rapidly and remains a key focus for the company, calling it “a very important market with dynamic, innovative customers.”

    The expo comes on the heels of China’s announcement of a 5.3 percent economic growth for the first half of the year despite rising challenges and external uncertainties.

    “China is entering a new cycle of market opportunity,” said Lin Chunmei, president and general manager of Corning Greater China, in an interview with Xinhua. “With the rise of AI and cloud technologies, the AI infrastructure market is growing faster than ever.”

    She noted that China’s steady and resilient economy, along with its stable and open business environment, continues to support the growth of enterprises. “Over the past few decades, we’ve seen consistent improvements in China’s business climate,” she added.

    At the opening ceremony, the CCPIT and global business representatives issued a joint initiative calling for supply chain stability and security, digital and green transformation, and stronger international cooperation.

    Ren Hongbin, chairman of the CCPIT, said the expo has become a platform for China’s high-standard opening up, urging collective efforts to safeguard multilateralism and build a more interconnected future.

    MIL OSI China News

  • MIL-OSI China: Eyeing China opportunities, multinational giants seek closer supply chain collaboration with Chinese partners

    Source: People’s Republic of China – State Council News

    Eyeing China opportunities, multinational giants seek closer supply chain collaboration with Chinese partners

    BEIJING, July 16 — As the third China International Supply Chain Expo opened Wednesday in Beijing, multinational companies are looking to strengthen supply chain collaborations in a move that will inject more certainty into the world economy.

    The five-day event has attracted 651 companies and institutions from 75 countries and regions. Overseas exhibitors account for 35 percent, a three-percentage-point increase from last year. Among the first-time multinational participants are major players such as Nvidia, Schneider Electric, L’Oreal, Louis Dreyfus and Medtronic.

    The growth in global participation highlights mounting confidence in the Chinese market and supply chain. The participating companies see China as both a stabilizing force and an innovation driver in the global supply chain.

    “The expo is an important gathering for innovation and collaboration, helping to strengthen the sustainable development of global manufacturing and international supply chains,” said Mohamed Kande, global chairman of PwC.

    CLOSER COLLABORATION

    The expo comes on the heels of China’s announcement of a 5.3 percent economic growth for the first half of the year despite rising challenges and external uncertainties.

    China’s steady economic growth, coupled with its robust supply chain and commitment to further opening up, positions it as a key partner for multinational companies.

    Jensen Huang, CEO of U.S. tech giant Nvidia, on Tuesday praised China’s rapid advancements in artificial intelligence (AI) during his visit to Beijing, describing the Chinese market as both “large” and “dynamic.”

    While speaking at the opening ceremony of the expo on Wednesday, Huang lauded China’s supply chain as a “miracle.” China’s open-source AI is a catalyst for global progress, giving every country and industry a chance to join the AI revolution, he said.

    “China is a very important country where the development of AI will continue to be very fast and we hope to be part of that,” Huang told reporters on Wednesday, adding that there’s so much opportunity and confidence in the Chinese market.

    Huang confirmed on Tuesday that Nvidia’s H20 chips will soon be available in the Chinese market again, following the U.S. government’s approval of the company’s filing licenses for shipping H20s to China.

    The expo has become a key venue for global firms to forge and expand supply chain collaborations.

    The expo serves as a platform for expanding McDonald’s supply chain partnerships, Xu Jansen, head of Impact Strategy at M (China) Co., Ltd. The fast food chain attended the expo for a second straight year, teaming up with 11 suppliers this year.

    Xu emphasized the importance of the Chinese market, noting that half of the 2,000 new McDonald’s stores opening each year globally are located here.

    The company has built a network of local suppliers and also helped many of them ship products overseas. China serves as a stabilizer to the global supply chain and global economic growth, Xu said in an interview.

    For French pharmaceutical giant Sanofi, the expo is also an opportunity to showcase its ecosystem and build collaborations.

    “Here, we explore innovative collaborations with our global partners, from R&D to production and patient accessibility enhancement, and share the latest results of localized practices,” said Wayne Shi, president of Sanofi Greater China. Sanofi will continue to support the Healthy China initiative with innovative drugs and vaccines, Shi said.

    RESILIENCE

    Business executives and experts assert that, given the current global economic climate, no single country can fulfill every role in industrial and supply chains. It is essential for countries to work together to achieve win-win results.

    Global firms view China as a pivotal destination for enhancing and diversifying their supply chains, owing to the country’s vast manufacturing capacity, robust industrial ecosystem, and improving business environment.

    Xiao Song, chairman, president and CEO of Siemens China, said that at a time when the global industrial landscape is undergoing rapid restructuring, the expo is becoming an important platform to promote the deep integration of all sections of the industrial chain.

    Siemens aims to help Chinese firms upgrade with digital and low-carbon technologies, helping build a green competitive edge globally as well as a more resilient and sustainable global industrial and supply chains, Xiao said.

    As the world’s first national-level exhibition focusing on supply chains, the expo is an internationally shared public product. First held in 2023, the expo has contributed to building more secure, stable, open and inclusive global industrial and supply chains.

    With over 70 special events and new alliances for exhibitors in each of the six supply chains showcased at the expo, the expo helps enterprises find partners, application scenarios and solutions, according to Ren Hongbin, chairman of the China Council for the Promotion of International Trade, the event’s organizer.

    Ren called on global business leaders to work together to uphold the multilateral trade system with the World Trade Organization at its core.

    Xu Jiabin, a professor at the Business School of Renmin University of China, said that as a manufacturing and trading powerhouse, China has made significant contributions to the stability and resilience of the global supply chain.

    “The expo will help mitigate the negative effects of trade barriers and safeguard the global international economic and trade order,” Xu said.

    MIL OSI China News

  • MIL-Evening Report: We were part of the world heritage listing of Murujuga. Here’s why all Australians should be proud

    Source: The Conversation (Au and NZ) – By Jo McDonald, Professor, Director of Centre for Rock Art Research + Management, The University of Western Australia

    Senior Ranger, Mardudunhera man Peter Cooper, oversees the Murujuga landscape Jo McDonald, CC BY-SA

    On Friday, the Murujuga Cultural Landscape in northwest Western Australia was inscribed on the UNESCO World Heritage List. We were in Paris to see Murujuga become Australia’s 21st world heritage property, but only our second property listed exclusively for its Indigenous cultural values.

    Murujuga, meaning “hip bone sticking out”, is an ancient rocky landscape rising out of the Indian Ocean in northwest Australia.

    Murujuga is shaped by the Lore and the presence of Ngarda-Ngarli – the collective term for the Traditional Owner groups of the coastal Pilbara – since Ngurra Nyujunggamu, when the earth was soft, the beginning of time.

    Murujuga includes the Burrup Peninsula, the Dampier Archipelago’s 42 islands and the listed property covers almost 100,000 hectares of land and sea country. Across this cultural landscape are between one to two million petroglyphs – rock art – created by carving designs into rock surfaces. The petroglyphs record Ngarda Ngarli’s attachment and adaptation to a changing environment through deep time.

    The UNESCO listing recognises the “outstanding universal value” of the Murujuga Cultural Landscape. This value lies in the traditional system governing it, in tangible and intangible attributes that attest to 50,000 years of Ngarda-Ngarli using and caring for the land and seascape.

    The Ngarda-Ngarli have campaigned for World Heritage Listing of the Murujuga Cultural Landscape for more than 20 years.

    Murujuga Board and Circle of Elders members in Sydney at the ICOMOS General Assembly, where they hosted a Symposium on the Cultural Landscape nomination.
    Jo McDonald, CC BY-SA

    A controversial nomination

    While the outstanding universal values of this place were not in question, the nomination became mired with broader climate concerns.

    Industrial development began at Murujuga in the 1950s and was established before Traditional Owners had decision-making authority. The Dampier Archipelago, as well as housing petroglyphs across 42 islands, is also home to one of the largest industrial hubs in the southern hemisphere.

    The recent approval for the North-West Gas Hub has elevated climate change concerns and raised questions about whether the government is serious about protecting Murujuga.

    The Murujuga Rock Art Monitoring Program (MRAMP) year two report was released around the same time as the north west gas hub announcement.

    While acidic pollution has been suggested by some, our work on the monitoring program found rain and dust at the site was pH neutral, and there is no acid rain impacting on the petroglyphs.

    Other criticism included that the air quality at the site is compromised by local gas production. The research found the air quality at Murujuga is “good” to “very good” by international standards. We also found average annual nitrogen dioxide levels − the emission under most scrutiny − is five times lower than World Health Organisation guidelines.

    According to MRAMP research, Murujuga’s air quality is well within national standards. Nitrogen dioxide is 16 times lower than the national standard, and sulphur dioxide never exceeding 10% of the national standard.

    Importantly, the research program is ongoing and will transition to monitoring led by the Ngarda-Ngarli with support and training from the scientists. And this ongoing monitoring will be part of the management regime in place to protect Murujuga as a world heritage listed site.

    The MRAMP monitoring team in action at Murujuga.
    Ben Mullins, CC BY-SA

    Ngard-Ngarli leadership

    Traditional Owners and Custodians led the world heritage nomination, supported by State and Commonwealth governments.

    Traditional Owners consider the listing will better protect Ngarda-Ngarli knowledge, lore and culture as expressed through the landscape and in the petroglyphs.

    World heritage recognition will support Ngarda-Ngarli decision-making and ongoing management across the Murujuga Cultural Landscape.

    This global recognition is a mechanism to help Ngarda-Ngarli do what they have always done: protect their culture and decide what is right for Country for future generations.

    The inscription is a testament to the old people who started this quest decades ago, many of whom have not lived to celebrate this victory.

    The Australian delegation on the floor of UNESCO during the inscription session.
    Jo McDonald, CC BY

    Australia’s deep time heritage

    Australia now has two places on the World Heritage List which are exclusively listed as Indigenous sites of outstanding universal value to all humanity.

    The Murujuga Cultural Landscape joins on the list the southwestern Victorian site Budj Bim, one of the world’s most extensive and oldest aquaculture systems.

    Murujuga Aboriginal Custodians celebrate the Word Heritage listing decision in Paris this week.
    Jo McDonald, CC BY

    By this listing, the world has recognised the deep time creative genius and ongoing connection of Ngarda-Ngarli to the Murujuga Cultural Landscape.

    This international acclaim recognises the extraordinary resilience of Australia’s First Nations peoples and should be a source of pride and celebration for all Australians.

    Jo McDonald is an employee of the University of Western Australia and receives funding from the Australian Research Council.The Centre for Rock Art Research and Management receives funding for its research and training operations from Rio Tinto. Jo was a member of the World Heritage committee and contributed to the writing of the dossier.

    Amy Stevens is an employee of Murujuga Aboriginal Corporation, which receives funding from the Australian Government, the WA Government and industry and was a lead author on the Murujuga Cultural Landscape World Heritage nomination.

    Belinda Churnside serves as Deputy Chair. Board Directors are remunerated for their duties in accordance with community-approved sitting fees. These payments are made from MAC’s operational income.

    MAC receives funding support for a range of projects from both State and Federal government departments, as well as from industry partners operating within the Burrup and Maitland Industrial Estate Agreement (BMIEA) area.

    The Department of Water and Environmental Regulation provides operational and strategic support for the Murujuga Rock Art Monitoring Program. The Department of Biodiversity, Conservation and Attractions funds MAC’s National Park Ranger Team, while other funding bodies contribute to the Murujuga Land and Sea Unit Rangers.

    All funding sources and expenditures are transparently reported in MAC’s annual financial report, which is audited each year by an independent external auditor.

    Ben Mullins is the lead scientist on the Murujuga Rock Art Monitoring Project, which is funded by the Government of Western Australia.

    Peter Hicks is the Chair of the Board of Murujuga Aboriginal Corporation (MAC). Board Directors are remunerated for their duties in accordance with community-approved sitting fees. These payments are made from MAC’s operational income.

    MAC receives funding support for a range of projects from both State and Federal government departments, as well as from industry partners operating within the Burrup and Maitland Industrial Estate Agreement (BMIEA) area.

    The Department of Water and Environmental Regulation provides operational and strategic support for the Murujuga Rock Art Monitoring Program. The Department of Biodiversity, Conservation and Attractions funds MAC’s National Park Ranger Team, while other funding bodies contribute to the Murujuga Land and Sea Unit Rangers.

    All funding sources and expenditures are transparently reported in MAC’s annual financial report, which is audited each year by an independent external auditor.

    Terry Bailey is a World Heritage advisor to Murujuga Aboriginal Corporation and WA Government and was lead editor and co-author of Murujuga Cultural Landscape World Heritage nomination. His appointment is funded by the WA Government.

    ref. We were part of the world heritage listing of Murujuga. Here’s why all Australians should be proud – https://theconversation.com/we-were-part-of-the-world-heritage-listing-of-murujuga-heres-why-all-australians-should-be-proud-261066

    MIL OSI AnalysisEveningReport.nz

  • MIL-Evening Report: We were part of the world heritage listing of Murujuga. Here’s why all Australians should be proud

    Source: The Conversation (Au and NZ) – By Jo McDonald, Professor, Director of Centre for Rock Art Research + Management, The University of Western Australia

    Senior Ranger, Mardudunhera man Peter Cooper, oversees the Murujuga landscape Jo McDonald, CC BY-SA

    On Friday, the Murujuga Cultural Landscape in northwest Western Australia was inscribed on the UNESCO World Heritage List. We were in Paris to see Murujuga become Australia’s 21st world heritage property, but only our second property listed exclusively for its Indigenous cultural values.

    Murujuga, meaning “hip bone sticking out”, is an ancient rocky landscape rising out of the Indian Ocean in northwest Australia.

    Murujuga is shaped by the Lore and the presence of Ngarda-Ngarli – the collective term for the Traditional Owner groups of the coastal Pilbara – since Ngurra Nyujunggamu, when the earth was soft, the beginning of time.

    Murujuga includes the Burrup Peninsula, the Dampier Archipelago’s 42 islands and the listed property covers almost 100,000 hectares of land and sea country. Across this cultural landscape are between one to two million petroglyphs – rock art – created by carving designs into rock surfaces. The petroglyphs record Ngarda Ngarli’s attachment and adaptation to a changing environment through deep time.

    The UNESCO listing recognises the “outstanding universal value” of the Murujuga Cultural Landscape. This value lies in the traditional system governing it, in tangible and intangible attributes that attest to 50,000 years of Ngarda-Ngarli using and caring for the land and seascape.

    The Ngarda-Ngarli have campaigned for World Heritage Listing of the Murujuga Cultural Landscape for more than 20 years.

    Murujuga Board and Circle of Elders members in Sydney at the ICOMOS General Assembly, where they hosted a Symposium on the Cultural Landscape nomination.
    Jo McDonald, CC BY-SA

    A controversial nomination

    While the outstanding universal values of this place were not in question, the nomination became mired with broader climate concerns.

    Industrial development began at Murujuga in the 1950s and was established before Traditional Owners had decision-making authority. The Dampier Archipelago, as well as housing petroglyphs across 42 islands, is also home to one of the largest industrial hubs in the southern hemisphere.

    The recent approval for the North-West Gas Hub has elevated climate change concerns and raised questions about whether the government is serious about protecting Murujuga.

    The Murujuga Rock Art Monitoring Program (MRAMP) year two report was released around the same time as the north west gas hub announcement.

    While acidic pollution has been suggested by some, our work on the monitoring program found rain and dust at the site was pH neutral, and there is no acid rain impacting on the petroglyphs.

    Other criticism included that the air quality at the site is compromised by local gas production. The research found the air quality at Murujuga is “good” to “very good” by international standards. We also found average annual nitrogen dioxide levels − the emission under most scrutiny − is five times lower than World Health Organisation guidelines.

    According to MRAMP research, Murujuga’s air quality is well within national standards. Nitrogen dioxide is 16 times lower than the national standard, and sulphur dioxide never exceeding 10% of the national standard.

    Importantly, the research program is ongoing and will transition to monitoring led by the Ngarda-Ngarli with support and training from the scientists. And this ongoing monitoring will be part of the management regime in place to protect Murujuga as a world heritage listed site.

    The MRAMP monitoring team in action at Murujuga.
    Ben Mullins, CC BY-SA

    Ngard-Ngarli leadership

    Traditional Owners and Custodians led the world heritage nomination, supported by State and Commonwealth governments.

    Traditional Owners consider the listing will better protect Ngarda-Ngarli knowledge, lore and culture as expressed through the landscape and in the petroglyphs.

    World heritage recognition will support Ngarda-Ngarli decision-making and ongoing management across the Murujuga Cultural Landscape.

    This global recognition is a mechanism to help Ngarda-Ngarli do what they have always done: protect their culture and decide what is right for Country for future generations.

    The inscription is a testament to the old people who started this quest decades ago, many of whom have not lived to celebrate this victory.

    The Australian delegation on the floor of UNESCO during the inscription session.
    Jo McDonald, CC BY

    Australia’s deep time heritage

    Australia now has two places on the World Heritage List which are exclusively listed as Indigenous sites of outstanding universal value to all humanity.

    The Murujuga Cultural Landscape joins on the list the southwestern Victorian site Budj Bim, one of the world’s most extensive and oldest aquaculture systems.

    Murujuga Aboriginal Custodians celebrate the Word Heritage listing decision in Paris this week.
    Jo McDonald, CC BY

    By this listing, the world has recognised the deep time creative genius and ongoing connection of Ngarda-Ngarli to the Murujuga Cultural Landscape.

    This international acclaim recognises the extraordinary resilience of Australia’s First Nations peoples and should be a source of pride and celebration for all Australians.

    Jo McDonald is an employee of the University of Western Australia and receives funding from the Australian Research Council.The Centre for Rock Art Research and Management receives funding for its research and training operations from Rio Tinto. Jo was a member of the World Heritage committee and contributed to the writing of the dossier.

    Amy Stevens is an employee of Murujuga Aboriginal Corporation, which receives funding from the Australian Government, the WA Government and industry and was a lead author on the Murujuga Cultural Landscape World Heritage nomination.

    Belinda Churnside serves as Deputy Chair. Board Directors are remunerated for their duties in accordance with community-approved sitting fees. These payments are made from MAC’s operational income.

    MAC receives funding support for a range of projects from both State and Federal government departments, as well as from industry partners operating within the Burrup and Maitland Industrial Estate Agreement (BMIEA) area.

    The Department of Water and Environmental Regulation provides operational and strategic support for the Murujuga Rock Art Monitoring Program. The Department of Biodiversity, Conservation and Attractions funds MAC’s National Park Ranger Team, while other funding bodies contribute to the Murujuga Land and Sea Unit Rangers.

    All funding sources and expenditures are transparently reported in MAC’s annual financial report, which is audited each year by an independent external auditor.

    Ben Mullins is the lead scientist on the Murujuga Rock Art Monitoring Project, which is funded by the Government of Western Australia.

    Peter Hicks is the Chair of the Board of Murujuga Aboriginal Corporation (MAC). Board Directors are remunerated for their duties in accordance with community-approved sitting fees. These payments are made from MAC’s operational income.

    MAC receives funding support for a range of projects from both State and Federal government departments, as well as from industry partners operating within the Burrup and Maitland Industrial Estate Agreement (BMIEA) area.

    The Department of Water and Environmental Regulation provides operational and strategic support for the Murujuga Rock Art Monitoring Program. The Department of Biodiversity, Conservation and Attractions funds MAC’s National Park Ranger Team, while other funding bodies contribute to the Murujuga Land and Sea Unit Rangers.

    All funding sources and expenditures are transparently reported in MAC’s annual financial report, which is audited each year by an independent external auditor.

    Terry Bailey is a World Heritage advisor to Murujuga Aboriginal Corporation and WA Government and was lead editor and co-author of Murujuga Cultural Landscape World Heritage nomination. His appointment is funded by the WA Government.

    ref. We were part of the world heritage listing of Murujuga. Here’s why all Australians should be proud – https://theconversation.com/we-were-part-of-the-world-heritage-listing-of-murujuga-heres-why-all-australians-should-be-proud-261066

    MIL OSI AnalysisEveningReport.nz

  • MIL-OSI: Recession Profit Secrets Offers Recession Remedy Strategy for Economic Resilience in 2025

    Source: GlobeNewswire (MIL-OSI)

    New York, July 16, 2025 (GLOBE NEWSWIRE) —

    Disclaimer: This content is for informational purposes only. Recession Profit Secrets products are not intended to diagnose, treat, cure, or prevent any disease. Always consult a healthcare provider before use.

    Visit the Official Recession Profit Secrets Site

    Understanding the Recession Profit Secrets Framework

    In a time when economic headwinds challenge traditional investment logic, the Recession Profit Secrets platform offers an alternative financial learning system rooted in strategic preparedness. Unlike high-risk investment schemes that often emerge during periods of volatility, this program emphasizes core economic resilience—a principle aligned with timeless financial planning fundamentals.

    At its core, the Recession Profit Secrets framework is designed to help individuals recognize recessionary signals in advance. The educational material prioritizes a blend of historical case studies, monetary policy trends, and behavioral finance strategies. Each lesson is structured to equip the average person with an analytical lens through which they can evaluate their own asset positioning, consumption patterns, and long-term fiscal health.

    The platform does not claim to predict market collapses, nor does it provide financial advice. Rather, it teaches principles that help consumers interpret economic context with greater clarity. The keyword “Recession Remedy” represents a broader philosophy: using knowledge—not speculation—to make better personal finance decisions in uncertain times.

    What Makes the ‘Recession Remedy’ Concept Unique in 2025

    In 2025, recession discourse has shifted from rare-event theory to continuous preparedness. The “Recession Remedy” concept introduces structured education modules that challenge consumers to examine their dependencies on interest-sensitive income, evaluate liquidity positions, and stress-test their household budgets.

    Unlike one-size-fits-all guides or emotionally driven forecasts, this program incorporates data from leading macroeconomic indicators such as the Consumer Price Index (CPI), GDP volatility, and the Federal Reserve’s forward guidance models. The Recession Profit Secrets team consolidates these elements into digestible formats accessible to non-professionals, with an emphasis on awareness rather than anxiety.

    Additionally, the platform offers detailed frameworks on capital preservation, explaining the difference between cyclical downturns and structural economic shifts. Whether addressing inflationary environments or debt cycle contractions, the “Recession Remedy” curriculum remains anchored in verifiable academic sources and financial journalism standards.

    Analyzing Economic Indicators and Market Trends

    Interpreting macroeconomic signals is essential for financial planning. Recession Profit Secrets dedicates extensive coverage to the most telling indicators of systemic stress. These include yield curve inversions, stagnating industrial production, consumer sentiment declines, and wage growth divergences.

    By breaking down these indicators into practical insights, the curriculum avoids overwhelming readers with technical jargon. Instead, it outlines how everyday economic developments—from grocery price surges to rising credit card APRs—can serve as early warnings for larger systemic shifts.

    This section also explores how market psychology, geopolitical uncertainty, and commodity cycles intersect to influence recession trajectories. Users are introduced to frameworks that encourage diversified income streams, conservative leverage practices, and flexibility in spending habits—three critical ingredients for financial durability.

    Learn more about how this framework works in real-world scenarios by visiting the Official Recession Profit Secrets Site.

    Protecting Household Wealth Before a Recession Hits

    While many programs focus on crisis response, Recession Profit Secrets focuses on pre-recession resilience. This includes guidance on fixed cost reduction, low-volatility income strategies, and recession-conscious budgeting techniques.

    Participants are encouraged to audit discretionary expenses, review insurance coverages, and consider adjustments to tax-withholding strategies. For those nearing retirement, modules explore how sequence-of-returns risk can impact drawdown plans—and what adjustments may help reduce volatility exposure.

    The “Recession Remedy” philosophy places strong emphasis on liquidity, arguing that access to cash reserves can reduce reliance on debt and allow strategic timing of asset decisions. The program offers no investment advice, but it does provide a playbook for increasing optionality in personal finance planning.

    How Consumers Are Shifting Financial Behavior in Uncertain Times

    Recent surveys suggest growing consumer appetite for financial literacy tools—particularly those aimed at reducing dependency on high-risk assets. The Recession Profit Secrets platform reflects this shift, offering modular instruction suited for all levels of experience.

    In 2025, younger consumers are prioritizing debt reduction, middle-aged households are exploring passive income strategies, and retirees are seeking inflation-sensitive allocation models. The program adapts to these generational differences by offering layered content—each module building on the last in a non-linear, self-paced structure.

    More broadly, the platform addresses the psychological side of economic stress: fear of job loss, anxiety over inflation, and pressure to sustain pre-recession lifestyles. It frames each lesson in terms of empowerment, helping users focus on action rather than apprehension.

    The Educational Design Behind Recession Profit Secrets

    The instructional design of Recession Profit Secrets follows a “concept-to-application” flow. Each topic begins with foundational definitions and economic context, followed by hypothetical case studies and end-of-module review checklists.

    Modules are built to foster knowledge retention through spaced repetition, context layering, and behavioral modeling. Visual learners benefit from infographics and charts that map out economic cycles and recessionary triggers.

    The program also includes access to periodic updates, ensuring that macro trends—such as fiscal policy changes, new federal reserve signals, or labor market shifts—are integrated into future course revisions. This living-document approach ensures the curriculum evolves in tandem with the economy itself.

    Why ClickBank’s Transparent Delivery Model Matters

    One distinguishing feature of the Recession Profit Secrets experience is its delivery through ClickBank, a global platform known for compliance standards and customer transparency.

    Consumers who access the product through ClickBank benefit from secure checkout, defined refund terms, and readily available support channels. This backend infrastructure ensures continuity, platform security, and access to updates without data risk or affiliate obfuscation.

    ClickBank’s reputation for delivering digital education securely and consistently makes it an ideal partner for programs like Recession Profit Secrets, where trust and clarity are critical to user adoption.

    Explore how the platform delivers secure digital access via ClickBank by visiting the Official Recession Profit Secrets Site.

    Debunking Common Myths About Recession-Proof Investing

    The Recession Profit Secrets platform directly addresses common misconceptions—such as the belief that gold is always a safe haven, or that cash hoarding is universally effective.

    Instead, the curriculum unpacks the nuances behind each perceived “safe” strategy. For example, while gold may act as a hedge during specific inflationary periods, its correlation to real purchasing power varies depending on geopolitical cycles.

    The platform discourages absolutism, advocating instead for a principles-first approach: understanding liquidity profiles, inflation pass-throughs, and the interplay of policy responses. The goal is to equip users with frameworks, not prescriptions.

    Who May Benefit Most from This Approach in 2025

    The Recession Profit Secrets curriculum may appeal to a broad audience—particularly those with fixed or limited incomes, pre-retirees, small business owners, and consumers carrying unsecured debt.

    Its accessibility makes it suitable for both new learners and experienced individuals looking to reframe outdated financial models. Those navigating job transitions, retirement recalibrations, or household budgeting stress may find particular value in the course’s situational application style.

    Rather than positioning the program as a cure-all, the content invites users to treat it as a toolkit—drawing from it selectively based on their current financial lifecycle.

    Final Thoughts on Building a Financially Resilient Future

    In a landscape increasingly shaped by debt cycles, fiscal uncertainty, and automation-driven job volatility, building financial resilience has become more than a goal—it’s a necessity.

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    The MIL Network

  • MIL-OSI United Kingdom: Great British Energy to cut energy bills for community facilities

    Source: United Kingdom – Executive Government & Departments 2

    Press release

    Great British Energy to cut energy bills for community facilities

    Great British Energy to cut energy bills for local community libraries, fire stations, care homes and community centres.

    • Libraries, fire stations and care homes in local communities will benefit from cheaper energy bills through Great British Energy community funding as part of Plan for Change 

    • Mayoral authorities to receive a share of £10 million for publicly-owned clean energy projects  

    • Complements Great British Energy’s drive to cut bills for around 200 schools and 200 hospitals, which is already seeing savings

    Libraries, fire stations and care homes in local communities will benefit from cheaper energy bills as Great British Energy delivers on the government’s clean energy superpower mission to make working people and their communities better off. 

    Great British Energy, the government’s publicly-owned clean energy company, has awarded mayoral authorities a share of £10 million in grant funding to roll out clean energy projects at the centre of communities – including rooftop solar on Merseyside care homes and on leisure centres and libraries in Yorkshire.  

    These grants will mean that the community services and institutions that working people use will be able to save on their electricity bills and spend more money on the frontline services that strengthen local communities and boost local economic growth.  

    It is estimated that these schemes could produce a total of around £35 million of lifetime savings on energy bills, while improving energy security and creating good jobs.   

    As well as solar panels on public buildings, the grants will pay to install batteries for community buildings in areas including Greater Manchester and West Yorkshire, so they can store renewable energy and use it later. The grants will also fund EV chargers in Greater Manchester, to make it easier for drivers to benefit from cheaper to power electric vehicles.   

    Great British Energy is already cutting energy bills for public services, with solar panels already installed on 11 schools as part of plans to roll out the panels on around 200 schools and 200 hospitals in England. 

    The government’s clean energy superpower mission will protect billpayers, create jobs and bring greater energy security through delivering clean power by 2030. Great British Energy will accelerate this by developing, investing and building clean energy projects across the UK. 

    Energy Secretary Ed Miliband said: 

    Your local sports hall, library and community centre could have their energy bills cut by Great British Energy, the government’s publicly-owned clean energy company.  

    Our plans will mean more money can be spent on the services that make working people better off and help strengthen the ties that bind us in our communities.  

    This is what Great British Energy is all about – taking back control to deliver lower bills for good.

    Great British Energy CEO Dan McGrail said: 

    Today’s support for new clean power projects in every region in England shows our mission in action – providing a lasting positive impact for the country by creating new jobs, lower bills, and a cleaner future. 

    It’s important that communities feel the benefits of the energy transition and that we demonstrate the very real rewards it can bring.

    Earlier this year, all Mayoral Strategic Authorities were invited to submit expressions of interest for funding renewable energy projects that can be delivered in the 2025/2026 financial year.  

    Liverpool City Region Combined Authority will use the money to support a rooftop solar project to support care homes and leisure centres, cutting  around £4.6 million on lifetime energy bills, while Greater Manchester will also roll out rooftop solar on libraries, fire stations, police stations and sports centres, leading to estimated savings of over £2.1million on lifetime bills. Projects in York and North Yorkshire are estimated to bring around £4 million in lifetime bill savings, they include solar panels to help power an Edwardian swimming pool in York and leisure centres in Whitby, Ripon and Thirsk. 

    It follows the government’s announcement in March to award £180 million of funding for schools and hospitals to install rooftop solar, marking the first major project for Great British Energy – a company owned by the British people, for the British people. This could see millions invested back into frontline services, targeting deprived areas, with lifetime bill savings for schools and the NHS sites of up to £400 million over the next 30 years.

    Notes to editors 

    Successful Mayoral schemes: 

    The figures below were estimated by DESNZ in collaboration with MSAs, based on a combination of project-level data and DESNZ standard assumptions. It should be noted these are initial estimates that will be refined as projects become operational and actual data is collected. 

    MSA Technology Project Type Grant Funding Requested (£) Total expected project cost (£) Estimated Net Yearly Average Energy Bill Savings  (£ undiscounted, 2025 prices) Estimated Net Lifetime Energy Bill Savings  (£ undiscounted, 2025 prices)
    Greater Lincolnshire Solar Leisure centres and fire stations £607,845 £627,845 TBC TBC
    South Yorkshire Solar Schools, outdoor covered market and library £572,025 £615,397 £51,938 £1,558,131
    Greater London Authority Solar Schools £607,838 £674,220 £30,376 £911,280
    Hull and East Yorkshire Solar Service buildings and car parks £700,000 £1,842,879 £89,822 £2,694,647
    Cambridgeshire and Peterborough Solar Police headquarters, car park and border canopies £700,000 £774,226 £51,630 £1,548,886
    Greater Manchester Solar, Battery and EV Libraries, fire stations, police stations and sports centres £695,900 £1,301,800 £71,846 £2,155,384
    North-East Solar Schools £700,000 £749,946 £46,060 £1,381,806
    York and North Yorkshire Solar Leisure centres, libraries, schools, transport sites £700,000 £1,219,948 £134,898 £4,046,936
    West Yorkshire Solar and Battery Police stations, Arrium plant nursery, primary school, sports centres and Lotherton Hall Estate £700,000 £1,154,838 £275,669 £8,270,082
    Tees Valley Combined Authority Solar Solar on roof of depot and public buildings £444,738 £444,738 £34,664 £1,039,911
    Liverpool City Region Solar Leisure centres and care homes £700,000 £760,319 £152,402 £4,572,054
    East Midlands Solar Former colliery £700,000 £1,900,000 £113,340 £3,400,200
    West Midlands Solar Schools £700,000 £820,000 £58,474 £1,754,207
    West of England Solar Schools £700,000 £1,657,522 £54,123 £1,623,697
    Total     £9,228,346 £14,543,678 £1,165,241 £34,957,222

    Updates to this page

    Published 17 July 2025

    MIL OSI United Kingdom

  • MIL-Evening Report: Is our mental health determined by where we live – or is it the other way round? New research sheds more light

    Source: The Conversation (Au and NZ) – By Matthew Hobbs, Associate Professor and Transforming Lives Fellow, Spatial Data Science and Planetary Health, Sheffield Hallam University

    Photon-Photos/Getty Images

    Ever felt like where you live is having an impact on your mental health? Turns out, you’re not imagining things.

    Our new analysis of eight years of data from the New Zealand Attitude and Values Study found how often we move and where we live are intertwined with our mental health.

    In some respects, this finding might seem obvious. Does a person feel the same living in a walkable and leafy suburb with parks and stable neighbours as they would in a more transient neighbourhood with few local services and busy highways?

    Probably not. The built and natural environment shapes how safe, supported and settled a person feels.

    We wanted to know to what extent a person’s mental health is shaped by where they live – and to what degree a person’s mental health determines where they end up living.

    Patterns over time

    Most research on the environmental influences on mental health gives us a snapshot of people’s lives at a single point in time. That’s useful, but it doesn’t show how things change over time or how the past may affect the future.

    Our study took a slightly different approach. By tracking the same people year after year, we looked at patterns over time: how their mental health shifted, whether they moved house, their access to positive and negative environmental features, and how the areas they lived in changed when it came to factors such as poverty, unemployment and overcrowding.



    We also looked at things like age, body size and how much people exercised, all of which can influence mental health, too.

    To make sense of such complex and interconnected data, we turned to modern machine learning tools – in particular Random Forest algorithms. These tools allowed us to build a lot of individual models (trees) looking at how various factors affect mental health.

    We could then see which factors come up most often to evaluate both their relative importance and the likely extent of their influence.

    We also ran Monte Carlo simulations. Think of these like a high-tech crystal ball, to explore what might happen to mental health over time if neighbourhood conditions improved.

    These simulations produced multiple future scenarios with better neighbourhood conditions, used Random Forest to forecast mental health outcomes in each, and then averaged the results.

    A negative feedback loop

    What we uncovered was a potential negative feedback loop. People who had depression or anxiety were more likely to move house, and those who moved were, on average, more likely to experience worsening mental health later on.

    And there’s more. People with persistent mental health issues weren’t just moving more often, they were also more likely to move into a more deprived area. In other words, poorer mental health was related to a higher likelihood of ending up in places where resources were scarcer and the risk of ongoing stress was potentially higher.

    Our study was unable to say why the moves occurred, but it may be that mental health challenges were related to unstable housing, financial strain, or the need for a fresh start. Our future research will try to unpick some of this.

    On the flip side, people who didn’t relocate as often, especially those in lower-deprivation areas, tended to have better long-term mental health. So, stability matters. So does the neighbourhood.

    Where we live matters

    These findings challenge the idea that mental health is just about what’s inside us. Where we live plays a key role in shaping how we feel. But it’s not just that our environment affects our minds. Our minds can also steer us into different environments, too.

    Our study shows that mental health and place are potentially locked in a feedback loop. One influences the other and the cycle can either support wellbeing or drive decline.

    That has real implications for how we support people with mental health challenges.

    In this study, if a person was already struggling, they were more likely to move and more likely to end up somewhere that made life harder.

    This isn’t just about individual choice. It’s about the systems we’ve built, housing markets, income inequality, access to care and more. If we want better mental health at a population level, we need to think beyond the individual level. We need to think about place.

    Because in the end, mental health doesn’t just live in the mind; it’s also rooted in the places we live.

    The authors do not work for, consult, own shares in or receive funding from any company or organisation that would benefit from this article, and have disclosed no relevant affiliations beyond their academic appointment.

    ref. Is our mental health determined by where we live – or is it the other way round? New research sheds more light – https://theconversation.com/is-our-mental-health-determined-by-where-we-live-or-is-it-the-other-way-round-new-research-sheds-more-light-260491

    MIL OSI AnalysisEveningReport.nz

  • MIL-OSI USA: Welch Spotlights Importance of Safeguarding Musicians and Artists from AI 

    US Senate News:

    Source: United States Senator Peter Welch (D-Vermont)
    WASHINGTON, D.C. — U.S. Senator Peter Welch (D-Vt.), a member of the Senate Judiciary Committee today emphasized the importance of establishing protections to help creators—musicians, artists, writers, and others—access the courts to protect their copyrighted works if and when they are used to train generative artificial intelligence (AI) models. Senator Welch urged Congress to pass the Transparency and Responsibility for Artificial Intelligence Networks (TRAIN) Act, bipartisan legislation that would allow copyright holders to access training records used for AI models to determine if their work was used—a process currently used for internet piracy.   
    “The AI companies need content, so they don’t care where it comes from. It’s just a voracious, insatiable appetite, and they’re going to go into copyrighted material. We know that, and to suggest they won’t, I think, is naïve. And the question, and the burden here is—that is going into copyrighted material. And the artist has the right to have that copyright respected. The burden is that how do you know they used it? That’s the whole point of the TRAIN Act, where if there is copyright infringement, a reasonable assertion of that and suspicion of it is going to require disclosure on the part of the AI platform,” said Senator Welch. 
    Watch Senator Welch’s full remarks below: 
    Read key excerpts from Senator Welch’s exchange with Michael Smith, Professor of Information Technology and Marketing at Carnegie Mellon University: 
    “Music is so important. It really helps people get a sense of who they are, it helps people connect, and it’s across political divisions. That’s what’s one of the inspiring things about the incredible contributions that musicians provide to our society. Can you just explain what the dangers are of allowing AI models to freely train off of copyrighted works?” asked Senator Welch.  
    Mr. Michael Smith testified: “There are multiple dangers…When you sign a license with a generative AI company, you’re signing with a gun to your head because they can say, ‘either sign what I’m offering or I’m going to go steal it instead.’ That’s troubling.” 
    Senator Welch: “This is the concern I have about how this AI…is going to make it tougher for those folks against great odds to keep at it. So maybe you could just—from your experience—talk a little bit about how it would adversely impact any chance they have of being able to pay their bills at the end of the month while they’re trying to create inspirational music for the benefit of all of us.” 
    Mr. Smith: “I deeply share that concern, Senator, and it’s based on peer-reviewed academic research showing that creative output goes down when piracy is allowed to flourish. I worry that the future David Baldaccis of the world won’t get through that hump. And we won’t get to appreciate their creative output if we allow piracy to be used to continue to train these generative AI models.”   
    Senator Welch is focused on strengthening consumer protections and safety around emerging technologies, including AI. Last Congress, Senator Welch introduced the Artificial Intelligence Consumer Opt-In, Notification Standards, and Ethical Norms for Training (AI CONSENT) Act, legislation that would require online platforms to obtain consumers’ express informed consent before using their personal data to train AI models. Senator Welch also introduced the Digital Platform Commission Act, legislation to create an expert federal agency to provide comprehensive regulation of digital platforms to protect consumers, promote competition, and safeguard the public interest. 
    Learn more about Senator Welch’s work by visiting his website or by following him on social media. 

    MIL OSI USA News

  • MIL-OSI USA: Capito, Colleagues Advocate for Critical Education Funding

    US Senate News:

    Source: United States Senator for West Virginia Shelley Moore Capito

    WASHINGTON, D.C. – U.S. Senator Shelley Moore Capito (R-W.Va.), chairman of the Senate Appropriations Subcommittee on Labor, Health and Human Services, Education, and Related Agencies (Labor-HHS), led a group of her colleagues in sending a letter to Russell Vought, Director of the White House Office of Management and Budget (OMB), advocating to release anticipated education formula funding—an issue she has heard about directly from impacted individuals.

    Specifically, the letter requests that the administration implement the Fiscal Year (FY) 2025 Full-Year Continuing Resolution Act, which President Trump signed into law earlier this year. This legislation contains critical funding that states rely on to help students, families, and local economies.

    In addition to Senator Capito, the following senators signed the letter: John Boozman (R-Ark.), Katie Britt (R-Ala.), Susan Collins (R-Maine), Deb Fischer (R-Neb.), John Hoeven (R-N.D.), Jim Justice (R-W.Va.), Mitch McConnell (R-Ky.), Lisa Murkowski (R-Alaska), and Mike Rounds (R-S.D.).

    Full text of the letter can be found here or below.

    Dear Director Vought, 

    We write to ask you to faithfully implement the Fiscal Year (FY) 2025 Full-Year Continuing Resolution Act, which President Trump signed into law earlier this year, including the education formula funds that states anticipated receiving on July 1, 2025.

    The Continuing Resolution contained funding for Supporting Effective Instruction State Grants; 21st Century Community Learning Centers; Student Support and Academic Enrichment Grants; English Language Acquisition; Migrant Education; Adult Basic and Literacy Education State Grants (including Integrated English Literacy and Civics Education State Grants). Withholding these funds will harm students, families, and local economies.

    The decision to withhold this funding is contrary to President Trump’s goal of returning K-12 education to the states. This funding goes directly to states and local school districts, where local leaders decide how this funding is spent, because as we know, local communities know how to best serve students and families. Withholding this funding denies states and communities the opportunity to pursue localized initiatives to support students and their families.

    We share your concern about taxpayer money going to fund radical left-wing programs. However, we do not believe that is happening with these funds. These funds go to support programs that enjoy longstanding, bipartisan support like after-school and summer programs that provide learning and enrichment opportunities for school aged children which also enables their parents to work and contribute to local economies. 

    These funds also go to support adult learners. These students are often adults seeking second chances for a myriad of reasons, for example, caregiving responsibilities or financial challenges. These are adult learners working to gain employment skills, earn workforce certifications, or transition into postsecondary education. We should be making educational opportunities easier for these students, not harder. 

    We welcome the opportunity to work with you and Secretary McMahon to ensure that all federal education funding goes towards programs that help states and school districts provide students an excellent education. We want to see students in our states and across the country thrive, whether they are adult learners, students who speak English as a second language, or students who need after-school care so that their parents can work. We believe you share the same goal.

    We encourage you to reverse your decision and release this Congressionally-approved funding to states. 

    Thank you for your attention to this request, and we look forward to your prompt reply.

    Sincerely,

    MIL OSI USA News

  • MIL-OSI New Zealand: Tourism – Southern Discoveries puts new emergency survival equipment to the test

    Source: Southern Discoveries

    Southern Discoveries has become the first tourism company in Milford Sound to be AF8-ready with specialist emergency survival equipment.

    The longest-running Milford Sound cruise operator has fitted out its entire fleet of vehicles, including five coaches seating up to 250 people, with survival gear specifically designed for major earthquake events.
     
    And the initiative has already got the attention of tourism trade partners.
     
    Yesterday, Southern Discoveries’ coach team and senior managers attended a simulated training exercise near Queenstown to familiarise themselves with the life-saving gear they may need in an emergency situation. The drill at Wilson’s Bay saw staff simulate realistic earthquake scenarios, practising shelter setup and testing rescue tools with the new equipment.
     
    The specialist survival equipment has been supplied by Christchurch-based company The Survival Co., whose owner Peter Gillman was on-site during yesterday’s training exercises.
     
    Gillman says Southern Discoveries’ investment in such an extensive range of survival and medical gear puts them ahead of others in the industry.
     
    “Southern Discoveries is the first tourism operator to take this level of equipment from The Survival Co.,” he says. “They’ve taken the approach that if you’re going to do it, you should do it properly, and that’s exactly what’s been achieved.”
     
    The Survival Co. created a tailor-made package for the company, considering the additional challenges of remote locations like Milford Sound.
     
    “We looked at the scenarios people might find themselves in and what particular hazards exist in these areas. This gear provides an opportunity to keep people safe and comfortable during an emergency situation until help arrives.”
     
    Each of Southern Discoveries’ five coaches is now equipped with long-life food supplies, bottled water, purification tablets, emergency shelter, headlamps, waterproof ponchos, survival blankets, personal hygiene items, and stretchers. The gear also includes four-person survival self-rescue backpacks, enabling passengers and drivers to evacuate safely if required, plus satellite communication devices with SOS and two-way texting capabilities to maintain contact in remote areas.
     
    Survival packs will be placed in nine company vehicles and all coaches will carry Heartshine Samaritan AEDs (Automated External Defibrillators) for immediate medical response capabilities. Grab-and-go packs have been placed in staff housing in Milford Sound.
     
    Southern Discoveries CEO Kerry Walker says the delivery of the gear aligns with the company’s goal of continuously improving and ensuring safety for guests and staff at all times.
     
    “We operate in a region with significant seismic risks, so it’s our responsibility to be prepared for any eventuality. This equipment provides genuine peace of mind for our staff, guests, and the local community,” Walker explains.
     
    The proactive safety initiative has already received strong support from Southern Discoveries’ international trade partners, particularly agents from the United States and Japan, who value the company’s commitment to safety standards.
     
    “We know our travel agent partners place high value on safety for their clients, so we’re delighted to be able to provide this level of comfort,” Walker adds.
     
    While Gillman notes his company is seeing increased interest from city councils and Civil Defence organisations, and is encouraged to see more tourism operators starting to invest in high-level survival equipment.
     
    Walker adds: “We’re proud to position ourselves as industry leaders in emergency preparedness, but we also want to encourage others to work with The Survival Co., who are experts in this area. One of Southern Discoveries’ major trade partners has already contacted The Survival Co. to discuss obtaining safety gear for their organisation.”
     
    About Southern Discoveries

    Southern Discoveries is a local, family-owned company dedicated to sharing some of New Zealand’s most iconic scenery and extraordinary experiences with the world. Operating for more than 70 years, Southern Discoveries is Milford Sound’s original cruise operator, offering a wide range of incredible sightseeing and adventure activities in Fiordland. The company maintains an ongoing commitment to the conservation of Aotearoa’s environment through sustainable tourism initiatives and the support of the Tawaki Project in partnership with DoC, the Fiordland Conservation Trust and the University of Otago.
    www.southerndiscoveries.co.nz

    MIL OSI New Zealand News

  • MIL-OSI Submissions: Moldova – Moldova Launches Agrotek Arena: A New Incubator for Digital Agriculture, Robotics, and FoodTech

    Source: Innovate Moldova Programme

    Chișinău, Moldova – Moldova is taking a decisive step toward the future of agriculture with the launch of a new incubator and pre-accelerator at Agrotek Arena Incubator, an innovation space dedicated to digital agriculture, robotics, and food technology. The initiative is part of the Innovate Moldova Programme, funded by Sweden, and aims to modernize the country’s agri-food sector through innovation, research, and international collaboration.

    On July 9, 2025, a Memorandum of Understanding was signed between the Moldova’s Ministry of Digitalization and Economic Development (MDED), the Technical University of Moldova (UTM), the Innovate Moldova Programme, and the Ukraine-Moldova American Enterprise Fund (UMAEF), marking the start of this strategic partnership.

    The incubator will span 1,300 square meters across two refurbished floors of Agrotek Arena and will host up to 30 residents – startups, student entrepreneurs, researchers, and agri-food businesses. It is projected to benefit over 3,000 students, farmers, and food processors annually by providing access to cutting-edge technologies, prototyping labs, greenhouses, and innovation support programs.

    “Agriculture remains a backbone of Moldova’s economy. Yet, without modern tools and forward-thinking infrastructure, its full potential cannot be realized, Agrotek Arena will serve as a launchpad for innovation, helping us bridge the gap between academia, industry, and global partners.”

    stated Doina Nistor, Deputy Prime Minister and Minister of Digitalization and Economic Development.

    The incubator is set to open its doors to residents by September 1st, with a structured acceleration program launching in October 2025. Activities will focus on developing viable agri-tech solutions in areas such as precision agriculture, smart irrigation, and sustainable food processing.

    Shared Investment and Global Collaboration

    The $1 million project is built on a shared funding model. Innovate Moldova Programme and UMAEF are supporting the refurbishment of common areas, while UTM is offering rent-free space and managing energy efficiency upgrades. Residents will contribute by equipping their dedicated offices with air conditioning, furnishings, and technical installations.

    Agrotek Arena will also establish strong linkages with European and North American technology providers. Strategic collaborations include:

    Davis Weather Stations for climate-smart farming,
    Biosfera’s GPS AgTech Solutions for resource-optimized agriculture,
    SAS Cropio ERP Systems for real-time farm data analytics.

    These partnerships not only bolster Moldova’s agricultural transformation but also create long-term business opportunities for EU, EFTA and North Atlantic region.

    A Foundation for Moldova’s AgriTech Future

    Located on UTM’s 5-hectare Mircești campus in capital Chișinău and linked to 570 hectares in Criuleni region, Agrotek Arena is the first major milestone in the broader Agrotek Park vision. Future plans include the development of high-tech farming sites, applied R&D centers, and repurposed Soviet-era infrastructure into labs and innovation hubs.

    “This is more than a building—it’s the beginning of Moldova’s transformation into a regional hub for sustainable agri-tech. By fostering ties between startups, universities, and international partners, we are laying the groundwork for high-value job creation and export-ready technologies.”

    said Sergiu Rabii, Programme Director at the Innovate Moldova Programme

    Agrotek Arena will also support Moldova’s alignment with EU standards by integrating sustainable design, ESG practices, and inclusive economic development into its operational model.

    MIL OSI – Submitted News

  • MIL-OSI United Nations: From diamonds to dirt: Sierra Leone youth bring land back to life

    Source: United Nations 2

    But now, parts of the land have been restored. Crops are beginning to flourish and bees are buzzing around once again.

    The people responsible for this change are a hodgepodge group – former taxi drivers and miners, people who barely finished secondary school and some with higher education degrees. The unifying factor? Most have youth on their side.

    There is life beyond mining [but] we all grew up with the mentality that diamond is the only solution,” said Sahr Fallah, chairman of the Youth Council in Kono.

    Over 44 percent of the 1.3 billion people aged 15-24 are employed in agrifood systems. However, this group often does not have the same access to resources as older generations. Moreover, they are sidelined in the conversations which might change this systemic exclusion.

    © UNICEF/Olivier Asselin

    Young men work on a diamond mining site near Koidu, Sierra Leone. (file)

    A lot of the time, what we find is that young people are included in policy processes but it is a little bit tokenistic. They don’t feel like their voice really matters,” said Lauren Phillips, a deputy director at the Food and Agriculture Organization (FAO).

    Decent work = economic growth

    The High-Level Political Forum on Sustainable Development in New York has been convened this week and next, to discuss progress – or lack thereof – towards the globally agreed Sustainable Development Goals (SDGs), one of which guarantees decent work for all.

    Despite this commitment, over half of the global workforce remains in informal employment, according to the Secretary-General’s report on the SDGs released Monday. This means that they do not have adequate social or legal protections.

    Decent work must be at the heart of macroeconomic planning, climate and diesel transitions and social recovery strategies,” said Sangheon Lee, director of employment policy at the International Labor Organization (ILO).

    Don’t ignore youth

    Like other vulnerable groups, young people face unique challenges in the agrifood sector. Specifically, they often lack land rights and will struggle to act collectively to protect their interests.

    “If you are not looking at data with a lens of age or gender, you are actually missing part of the story,” Ms. Phillips said.

    Among these assets are land titles – which the elderly may be reluctant to pass down because of insufficient social protections. Youth also are less able to access credit so they can invest in themselves and their families.

    Betty Seray Sam, one of the young farmers in Kono, said that her family never used to come to her when they were going through a crisis – they knew that she had no money and a child to support.

    © FAO/Heba Khamis

    Young farmers load tomatoes onto trucks in Nubaria, Egypt.

    But now, through an agricultural job in Kono, she can support her family during times of crisis.

    This project has had a rippling effect for the youth in terms of not only improving their livelihoods but also the livelihoods of their families,” said Abdul Munu, president of Mabunduku, a community-based farmer’s organization in Kono.

    Bee a farmer

    Providing training to young people in agrifood systems is absolutely essential to ensure that they can practice sustainable agriculture.

    In Chegutu, Zimbabwe, FAO has helped establish Bee Farmers Schools where young people are taught how to support apiaries through hands-on training activities.

    “The idea is that one of the apiaries can be turned into a classroom where youth from different parts of a district can come just like a school,” said Barnabas Mawire, a natural resource specialist at FAO.

    This training has helped support local youth beekeepers to move beyond local and small-scale honey production to a fully-fledged business model that has the potential to not just fight poverty but actually create local wealth.

    Evelyn Mutuda, the young entrepreneurs representative in Chegutu, aspires to plant Jacaranda trees which she says will improve the quality of the bees’ honey and enable the beekeepers to export beyond local markets.

    “We want to maximize all the profits so we can become better and bigger,” Ms. Mutuda said.

    From Facebook to TikTok

    Being able to form labour associations is one of the key factors of decent work. This sort of collective action is even more important for youth in agrifood who often lack the social capital to enact real policy change.

    “Young people are just starting out, making bonds within their group but also with people outside of their group. Those bonds are important…because there is power in numbers,” Ms. Phillips said.

    She also noted that young people are forming these bonds across geographic distances, often by using technology. Agrifood influencers on Instagram and TikTok, for example, are increasingly shaping conversations about the sector.

    Ms. Phillips also noted that it is important to think of collective action for youth as intergenerational.

    “While the report is focused on young people, it’s not ignorant of the fact that young people live in families…There is a lot which talks about the need for solidarity between generations,” Ms. Phillips said.

    Youth optimism

    The next generation will be the stewards of the food we eat, so integrating them into that system now is essential for future food security and sustainability.

    Many youth integrate tradition with innovation, creating sustainability and community resilience,” said Venedio Nala Ardisa, a youth representative at the Asia Indigenous Peoples Pact, at an online side event during the high-level forum.

    Angeline Manhanzva, one of the beekeepers in Chegutu, said that the opportunity to become a beekeeper changed her life. One day, she dreams of owning her own bee farm.

    “I will be an old person who has so much wealth and is able to buy her own big land to keep my hives and process my own honey.” 

    MIL OSI United Nations News

  • MIL-OSI USA: Murkowski, Colleagues Advocate for Critical Education Funding

    US Senate News:

    Source: United States Senator for Alaska Lisa Murkowski

    07.16.25

    Washington, DC – U.S. Senator Lisa Murkowski (R-AK) joined her colleagues in a letter to the Director of the Office of Management and Budget (OMB), Russell Vought, asking him to faithfully implement the Fiscal Year (FY) 2025 Full-Year Continuing Resolution Act, and release the funds.

    The legislation included funding for Supporting Effective Instruction State Grants; 21st Century Learning Centers; Student Support and Academic Enrichment Grants; English Language Acquisition; Migrant Education; Adult Basic and Literary Education State Grants (including Integrated English Language and Civics Education State Grants).

    “The decision to withhold this funding is directly contrary to President Trump’s goal of returning K-12 education to the states,” the Senators wrote. “This funding goes directly to states and local school districts, where local leaders decide how this funding is spent, because as we know, local communities know how to best serve students and families. Withholding this funding denies states and communities the opportunity to pursue localized initiatives to support students and their families.”

    The letter was also signed by Senators Shelley Moore Capito (R-WV), Susan Collins (R-ME), John Boozman (R-AR), Katie Boyd Britt (R-AL), Deb Fischer (R-NE), John Hoeven (R-ND), Jim Justice (R-WV), Mitch McConnell (R-KY), and M. Michael Rounds (R-SD).

    The full text of the letter can be found here, or below.

    Dear Director Vought,

    We write to ask you to faithfully implement the Fiscal Year (FY) 2025 Full-Year Continuing Resolution Act, which President Trump signed into law earlier this year, including the education formula funds that states anticipated receiving on July I, 2025.

    The Continuing Resolution contained funding for Supporting Effective Instruction State Grants; 21st Century Community Learning Centers; Student Support and Academic Enrichment Grants; English Language Acquisition; Migrant Education; Adult Basic and Literacy Education State Grants (including Integrated English Literacy and Civics Education State Grants). Withholding these funds will harm students, families, and local economies.

    The decision to withhold this funding is contrary to President Trump’s goal of returning K-12 education to the states. This funding goes directly to states and local school districts, where local leaders decide how this funding is spent, because as we know, local communities know how to best serve students and families. Withholding this funding denies states and communities the opportunity to pursue localized initiatives to support students and their families.

    We share your concern about taxpayer money going to fund radical left-wing programs.

    However, we do not believe that is happening with these funds. These funds go to support programs that enjoy longstanding, bipartisan support like after-school and summer programs that provide learning and enrichment opportunities for school aged children which also enables their parents to work and contribute to local economies.

    These funds also go to support adult learners. These students are often adults seeking second chances for a myriad of reasons, for example, caregiving responsibilities or financial challenges.

    These are adult learners working to gain employment skills, earn workforce certifications, or transition into postsecondary education. We should be making educational opportunities easier for these students, not harder.

    We welcome the opportunity to work with you and Secretary McMahon to ensure that all federal education funding goes towards programs that help states and school districts provide students an excellent education. We want to see students in our states and across the country thrive, whether they are adult learners, students who speak English as a second language, or students who need after-school care so that their parents can work. We believe you share the same goal.

    We encourage you to reverse your decision and release this Congressionally-approved funding to states.

    Thank you for your attention to this request, and we look forward to your prompt reply.

    MIL OSI USA News

  • MIL-OSI United Kingdom: PM set to reshape how Government works with communities to tackle Britain’s biggest challenges

    Source: United Kingdom – Executive Government & Departments

    Press release

    PM set to reshape how Government works with communities to tackle Britain’s biggest challenges

    The Prime Minister will launch the Civil Society Covenant – a new way of working that puts people at the heart of government.

    • Charities, faith groups, social enterprises and impact investors recognised as essential partners in tackling the country’s biggest challenges and deliver on the Plan for Change
    • Ministers and community leaders gather at a national summit to show how collaboration is already delivering – and will go further.

    The Prime Minister will join community leaders, campaigners, and charities from across the UK to launch the Civil Society Covenant – a new approach that listens, learns and delivers alongside those on the frontline.

    In his keynote speech, the Prime Minister will reflect on a promise made 18 months ago in opposition: to work in genuine partnership with civil society in the national interest. Since taking office, that promise has become reality – resetting the relationship between government and the people working every day to make their communities stronger.

    At its core, the Covenant is about delivering real change for working people – strengthening public services, creating safe communities, and providing new opportunities for communities to thrive. It gives civil society a home at the heart of government and recognises that national renewal can’t be delivered from Westminster alone.

    The summit brings together leaders from charities, faith organisations, philanthropists, social investors and grassroots groups to focus on the UK’s most urgent issues – from healthcare access to tackling violence against women and girls. These are challenges that disproportionately affect working families, and the Covenant ensures their voices are heard and their needs are met.

    It will show how civil society leadership, backed by government support, is already delivering results. As seen by:

    • Tackling domestic abuse: The Drive Project, a third-sector initiative, has seen percentages of perpetrators using physical abuse cut by 82%. The government is investing £53 million to expand the programme across England and Wales, working to tackle the behaviour of perpetrators and protect victims.
    • Supporting vulnerable children and families: Newly launched £500 million Better Futures Fund will support up to 200,000 children and families through early intervention. This is being matched by local and philanthropic investment.
    • Transparent immigration: Over 10 million people have transitioned to a digital immigration status, supported by 72 local organisations helping vulnerable communities. This system strengthens border security, reduces fraud, and ensures only those with the right to be here can access services.
    • Building the workforce we need: A new Labour Market Evidence Group is helping reduce reliance on overseas recruitment by boosting domestic skills and training.

    This is about rebalancing power and responsibility,” the Prime Minister will say.

    Not the top-down approach of the state working alone. Not the transactional approach of markets left to their own devices. But a new way forward – where government and civil society work side by side to deliver real change.

    The Civil Society Covenant has been shaped by over 1,200 organisations since it was first announced in October 2024. From national charities, trade unions and local campaigners, it sets out how government and communities will work together to deliver lasting change.

    Ahead of speaking at the Summit later today, Culture Secretary Lisa Nandy said:

    The Civil Society Covenant is about delivering real results for working people. It marks a shift from a government that kept civil society at arm’s length to one that actively partners with it, on equal footing.

    Our charities, volunteers, and social enterprises are embedded in the communities they serve and trusted by the people they support. That makes them the perfect partners for shaping the change we need.

    By working together, we’ll improve public services, make them more responsive and rooted in local needs, and ensure that every community benefits as part of our Plan for Change.

    The summit will spotlight how this partnership works in practice. Following the Prime Minister’s keynote, mission-led sessions will include:

    • Jess Phillips, Minister for Safeguarding, and Alex Davies-Jones, Minister for Victims and Violence Against Women and Girls, chairing a Safer Streets panel with campaigners.
    • Bridget Phillipson, Education Secretary, outlining how civil society will support the Opportunity Mission.
    • Darren Jones, Chief Secretary to the Treasury, talking about how a mission-driven government can work in partnership with impact investors and philanthropists
    • They will be joined by civil society leaders delivering change across the country, in areas such as early years support, health and violence against women and girls. 

     The Covenant will play a key role in delivering the government’s Plan for Change—supporting the opportunity mission by breaking down barriers for young people, helping to build an NHS fit for the future, and ensuring that no community is left behind.

    As part of the Summit, the government will also announce:

    • A new Joint Civil Society Covenant Council to drive delivery. The Joint Council will set direction and provide strategic oversight for implementation of the Covenant. It will have cross-sector membership comprising senior leaders from civil society and senior representatives from government departments to provide a key forum for driving progress in the reset of the relationship between government and civil society.
    • A Local Covenant Partnerships programme to support collaboration between civil society, councils and public services in communities that need it most.

    ENDS

    Additional quotes: 

    Sarah Elliott & Jane Ide, CEO’s of National Council for Voluntary Organisations & Association of Chief Executives of Voluntary Organisations on behalf of the Civil Society Advisory Group said:

    The challenges our country face can only be tackled by working together. The launch of the Civil Society Covenant is a key step forward in building a more collaborative and sustainable relationship between civil society and the UK government, while recognising our sector’s independence. Real and lasting change requires a partnership that is equal, honest and fair, with an intention to put lived experience at the heart of policy decision making.   

    The Civil Society Covenant sets out solid principles for how we work together. Now the test is putting them into practice, both nationally and locally. As organisations rooted in communities across the UK, we’ll hold ourselves and the government accountable, speaking up on behalf of the people and communities we represent and working together to ensure meaningful and lasting impact.

    Scottish Council for Voluntary Organisations Chief Executive Anna Fowlie, said:

    SCVO welcomes the publication of the UK Government’s Civil Society Covenant, which recognises the independence of, and the vital role played by, voluntary organisations in our communities, society, and democracy.

    Today is a starting point. The words on the page must now be made real—and that requires sustained effort, open dialogue, and, crucially, a genuine commitment to a partnership of equals.

    We welcome the Covenant’s recognition of the different contexts in which the voluntary sector operates across the UK—and, importantly, its commitment to respect and complement these.

    Wales Council for Voluntary Action, Chief Executive Lindsay Cordery-Bruce said:

    We welcome the Civil Society Covenant as a first step towards building a stronger, more respectful relationship between civil society and UK Government.

    We’re pleased to have been part of shaping this new approach, and welcome its alignment with the strong partnership structures we already have in place in Wales. The real test will now be in its implementation.

    We look forward to working together to ensure the Covenant is embedded in day-to-day practice and delivers meaningful improvements in how government and the sector work in partnership across the UK.

    Chief Executive of the Northern Ireland Council for Voluntary Action, Celine McStravick said:

    We warmly welcome the launch of the Civil Society Covenant as an important step in recognising the vital role civil society plays across the UK. In a devolved context like Northern Ireland, where community voices are central to local progress and peacebuilding, this commitment to partnership is especially significant.

    We look forward to ensuring the Covenant is embedded alongside our own partnership structures in Northern Ireland, and supports communities here to thrive.

    Notes to editors:

    • More information will be available at the Civil Society Covenant Hub on GOV.UK.
    • The summit is supported by Lloyds Bank Foundation for England and Wales and Pro Bono Economics. More information will be available at the Civil Society Covenant Hub on GOV.UK.
    • The Covenant is intended to complement and respect existing governance and partnership arrangements in Scotland, Wales and Northern Ireland, working alongside the distinct frameworks in each nation. The UK government will continue to work in partnership with civil society organisations in all four parts of the UK.

    Updates to this page

    Published 16 July 2025

    MIL OSI United Kingdom

  • MIL-OSI New Zealand: Search

    Source: Tertiary Education Commission

    Cyber security webinars
    Modified 19 June 2024
    Over the last year, the Cyber Security for the Tertiary Sector initiative facilitated online webinars to help organisations in the New Zealand tertiary education sector to better understand cyber security and help them decide what steps they can take to become more secure.
    https://www.tec.govt.nz/teo/working-with-teos/improving-cyber-security-in-the-tertiary-sector/how-to-improve-your-cyber-security

    MIL OSI New Zealand News

  • MIL-OSI United Kingdom: expert reaction to two papers on the use of mitochondrial donation and preimplantation genetic testing for mitochondrial disease, as published in NEJM

    Source: United Kingdom – Executive Government & Departments

    Two papers published in NEJM look at the use of mitochondrial donation an preimplantation genetic testing for mitochondrial disease.

    Dr David J Clancy, Lecturer in Biogerontology, Lancaster University, said:

    “This comment is to discuss Mitochondrial Replacement Therapy (MRT) in terms of costs and benefits in light of what we now know.

    Benefits

    “Mitochondrial replacement therapy allows women with pathogenic mitochondrial DNA to have a baby which bears her own chromosomes, while reducing or replacing the pathogenic mtDNA. If the primary purpose is to avoid mitochondrial disease, then women could also have IVF by donor sperm or donor egg (or donor embryo), or they might choose adoption if IVF technologies don’t suit them for clinical or personal reasons.

    “In chromosomal dominant diseases like Huntington’s disease, affected people are offered pre-implantation genetic testing (PGT) and they are also offered IVF using donor eggs or embryos if the patient is a woman. For these sorts of genetic disease there is currently no alternative. In these cases a woman cannot have a child bearing her own chromosomes.

    “When having a family there are two ways to break genetic lineages – inheritance down generations: one is to adopt and another is to have IVF by donor sperm or donor egg (or donor embryo). It is difficult to value genetic lineage. It will be more valuable to some, less to others. While maternity is never in doubt, paternity often is. Perhaps we should then value maternal genetic lineage more than paternal. Mitochondrial replacement therapy allows unbroken maternal lineage.

    I cannot determine whether the Mitochondrial Reproductive Advice Clinic suggests IVF by donor egg or embryo (or adoption). The paper says “Patients with heteroplasmy (part pathogenic mitochondrial DNA, part healthy) were offered PGT, and patients with homoplasmy or elevated heteroplasmy (all or mostly pathogenic mitochondrial DNA) were offered pronuclear transfer.”

    Costs

    “The money cost is presumably significant. The work was funded by Wellcome and NHS England and carried out by Newcastle University, UK and the Newcastle upon Tyne Hospitals NHS Foundation Trust. Presumably they could give an idea of the cost. This might be considered important, in an environment of limited resources for national healthcare.

    Possible harms

    “Because these babies would not exist without the MRT intervention, we want to know about possible problems; in medicine the saying is “First, do no harm”, though in current healthcare, harm is often inevitable. While the babies so far seem probably unaffected, assessing the potential for future harm as they develop by looking at the degree of heteroplasmy in the infants is a large part of the reason for the publications.

    “Measurements were on white blood cells so we don’t know about tissue mosaicism, which is where you can have high heteroplasmy in some tissues and low in others, and is common in many mitochondrial diseases. In tissues demanding high energy production (e.g. neurons), lower levels of heteroplasmy can still be symptomatic. In a mouse model, a proportion of >20% energy-deficient neurons in the brain was necessary for observable symptoms.

    “Three of eight newborns from MRT had heteroplasmy levels of 5%, 12%, and 16% (the other five were

    “All of these things were mostly known before these publications, so apparently the Human Fertilization and Embryology Authority (HFEA), who approved it, is happy with the cost-benefit ratio. It also appears that other countries also approve, because the technique is spreading; there is a clinic in North Cyprus, and Prof Mary Herbert, the study’s lead, has moved to a pioneer institution in IVF, Monash University in Melbourne, Australia, partly to introduce a mitochondrial replacement program.”

     

    Prof Joanna Poulton, Professor and Honorary Consultant in Mitochondrial Genetics, Nuffield Department of Women’s and Reproductive Health, said:

    “From this study, it isn’t clear that MD (mitochondrial donation)  has any advantage over PGT (pre-implantation genetic testing, an alternative strategy) for heteroplasmic mtDNA disorders (where patients have mixtures of normal and mutant mtDNA and severity depends on the “dose” of mutant). The “take home baby” rate and the reduction in mutant load is similar (if anything less good for MD).

    “MD has a clear theoretical advantage for homoplasmic disorders (where the mother’s mtDNA is 100% mutant), because while PGT while can be used to reduce risk, it cannot be used to reduce the load of mutant mtDNA. Over half of the MD children were from Leber Hereditary Optic Neuropathy (LHON) families, where the chance of male offspring going blind in adolescence is around 20% but only 4% for females. The risk of blindness can be reduced 5 fold using PGT to select female embryos, but they risk transmitting it to their children. Happily, male identical twins were born by MD with undetectable mutant mtDNA, they will be very low risk for blindness and as males, they will not transmit the problem to their children (because LHON is a maternally transmitted disorder). Slightly worryingly, one baby from a m.4300A>G family, where the mother has a heart disorder (cardiomyopathy) for which she may ultimately need a heart transplant, has an unspecified heart defect: they conclude it is probably unrelated to m.4300A>G but this remains uncertain. Another from a m.3260A>G family had a mutant load of 16% in blood. While this probably means the risk of symptoms is low, one symptomatic m.3260A>G woman had a blood level that was lower than this (11% with 81% in muscle).  Happily, male identical twins were born by MD with undetectable mutant mtDNA, they will be very low risk for blindness and as males, they will not transmit the problem to their children because LHON is a maternally transmitted disorder.

    “A great deal of research funding has been channelled into the centre that has developed MD. While this has generated fascinating scientific data and this treatment option is now available on the NHS, it hasn’t yet resulted in a dramatic clinical advance. Time will tell.”

    Prof Dusko Ilic, Professor of Stem Cell Science, King’s College London, said:

    “A remarkable accomplishment! State-of-the-art technology. Kudos to the team!”

     

    Prof Dagan Wells, Professor of Reproductive Genetics, University of Oxford, and Director, Juno Genetics, Oxford, said:

    “This is an important study which has been eagerly anticipated ever since the first license to carry out mitochondrial replacement therapy to avoid mitochondrial disease was granted eight years ago.

    “The results indicate that established methods for avoiding mitochondrial DNA diseases, such as preimplantation genetic testing, perform well and will be suitable for most women at risk of having an affected child.

    “A minority of patients are unable to produce any embryos free of mitochondrial disease, and for those women the study provides hope that they may be able to have healthy children in the future.

    “The treatment has succeeded in producing 8 babies, and although mitochondrial DNA mutations can be detected in the cells of most of the children, the great majority of their mitochondria are functional, and consequently they do not have mitochondrial disease.

    “The published results are very valuable, but some scientists will be a little disappointed that so much time and effort has, so far, only led to the birth of 8 children.

    “Larger studies will be needed to truly understand the value of mitochondrial replacement therapy, and to understand whether there are any risks associated with the treatment.

    “Three of the eight children born have some evidence of ‘reversal’, a phenomenon where the therapy initially succeeds in producing an embryo with very few defective mitochondria, but by the time the child is born the proportion of abnormal mitochondria in its cells has significantly increased.

    “It is not understood why reversal sometimes occurs. Taking data from the new study as well as previous research, it seems that it may affect as many as one-third of embryos produced using mitochondrial replacement therapy. Importantly, all the children in the study have low levels of abnormal mitochondria in their cells, including those where a degree of reversal has occurred. However, the fact that reversal can happen suggests there is a chance that mitochondrial replacement therapy might occasionally fail, and consequently the procedure should be seen as a way of reducing the risk of mitochondrial disease inheritance, not guaranteeing it.”

    Dr Andy Greenfield, Honorary Fellow at the Nuffield Department of Women’s & Reproductive Health, University of Oxford, said:

    “Mitochondria are the energy-producing organelles of the body’s cells.  They contain DNA (mitochondrial DNA, mtDNA) and as such are prone to changes to that DNA (mutations) that can disrupt mitochondrial function and cause disease. The paper by Hyslop et al describes the first clinical use in the UK of a technique – mitochondrial donation (MD) – aimed at reducing the risk of transmitting a class of mitochondrial diseases (mtDNA diseases) from mother to offspring. This is an often devastating and life-limiting group of diseases for which no curative treatments exist. The specific technique described, based on IVF, is pronuclear transfer (PNT), one of the two MD techniques made lawful in the UK in 2015. The last preclinical review of the safety and effectiveness of MD, commissioned by the HFEA and published in 2016, recommended its clinical use as a risk reduction strategy – to be used only in those women for whom preimplantation genetic testing (PGT, an established procedure that is used to detect genetic abnormalities, including the amount of disease-causing (pathogenic) mtDNA, in an embryo) followed by selection of an embryo with low levels of pathogenic mtDNA for transfer was unlikely to be a successful strategy i.e. only in those women with high levels of pathogenic mtDNA (elevated heteroplasmy) in all eggs or with exclusively pathogenic mtDNA in their eggs (homoplasmy). This cautious approach is at the heart of this new report, which, along with an accompanying paper by McFarland et al, assesses MD alongside PGT in an integrated programme performed at Newcastle Fertility Centre, UK, under the regulatory framework developed by the HFEA.

    “Whilst PGT for mtDNA is an established procedure that acts as a useful comparator, the attention here will be rightly focused on the MD clinical data: 22 women at high risk of transmitting mitochondrial disease to their offspring were treated using PNT, resulting in 8 live births and one ongoing pregnancy. Firstly, this headline result alone is highly significant: PNT is compatible with embryo viability in humans. Secondly, levels of pathogenic mtDNA (in blood) from the infants varied from 0% to 16%. Whilst the last figure hints at a degree of reversion to the maternal mtDNA type, it is also sufficiently low to conclude that the procedure has successfully reduced the risk of mtDNA in all children born. The amount of maternal mtDNA could, however, vary from tissue to tissue and so follow-up of these children is vitally important. McFarland et al report that none of the children has any health condition that could be straightforwardly attributed to the presence of mtDNA disease. As the authors note, there are reasons to be optimistic about the outcome of this first MD treatment in the UK.

    “The data in the last paragraph, whilst summarised very briefly, are the culmination of decades of work: from the earliest investigations in mice aimed at understanding the impacts of nuclear transfer, through to targeted experiments in human embryos to provide preclinical evidence of safety and effectiveness. But this is to focus only on some of the scientific/technical challenges that have been overcome. There were parallel activities over a similar time frame concerning ethical inquiry, public and patient engagement, law-making, drafting of regulations and execution of those regulations by committees. And last but not least: the careful establishment of a clinical pathway by which the health of the mothers and infants born could be monitored and they could be cared for (detailed in McFarland et al). This all represents a vast amount of work by a large number of people over a long period.

    “The Hyslop et al paper itself is a treasure trove of data, which will likely to be the starting points of new avenues of research and opportunities for refinement. What is the explanation for the somewhat elevated maternal mtDNA levels (still beneath the clinical threshold for disease) detected in two babies born following PNT? Further studies of mitochondrial DNA replication, segregation and interaction with the nuclear DNA may provide clues. The reduction in normally fertilized eggs in the PNT group also requires explanation and may indicate that some mtDNA pathogenic variants can compromise fertilisation of the egg, which is an energy-demanding process. This observation opens up a whole area of research concerning the role of played by mitochondria in fertility. Of course, numbers analysed here are still low and a larger and more diverse cohort will be required to draw firm conclusions about efficacy and safety of MD at a population level. We can look forward to future assessments of maternal spindle transfer (the other lawful MD technique in the UK) and even, possibly, the use of targeted, enzymatic degradation of pathogenic mtDNA to eliminate the risk of carry-over and reversion.

    “How do we summarise what this all means? It is a triumph of scientific innovation in the IVF clinic – a world-first that shows that the UK is an excellent environment in which to push boundaries in IVF; a tour de force by the embryologists who painstakingly developed and optimised the micromanipulation methods; an example of the value of clinical expertise, developed over decades of working with children and adults suffering from these devastating diseases, being used to support a new intervention and subsequent follow-up, potentially for many years. And it is so much more, depending on whether one’s perspective is that of an historian, sociologist, ethicist or philosopher. It is tempting to suggest that this report marks the end of a process – but it is actually the beginning, of a new era in which technologies that change how we think about human reproduction are introduced into a tightly regulated environment – the only way in which they should be introduced.

    “In time, there will no doubt be retrospective studies and assessments of how all this was done – some critical – and there will be much to learn. It is hoped that other papers will follow, detailing different aspects of the process by which these first UK children were born, because this whole exercise has been a steep learning curve for all involved and future progress relies on such learning being shared. Safety assessment should be at the heart of all these and future reports. Some may wonder about the time taken for these current reports to see the light of day – but that would be to underestimate what is required to transition from preclinical research activities in an academic setting to offering a bona fide clinical service on the NHS (with the spanner of COVID-19 thrown into the works for good measure). Others will wonder whether supporting the desire to have biological children merits all this time and effort, when ‘unmet clinical need’ is the focus and budgetary constraints are the norm. But this evaluation unnecessarily attempts to marginalise a human activity – ‘having children’ – that is actually central to the health and wellbeing of a significant proportion of the population. And those ordinary resemblances that parents and children often share also matter to them. Of course, the results of clinical follow-up of the children born using PNT will be a major determinant of the future prospects for mitochondrial donation in the IVF clinic, as this report acknowledges.

    “There will be many responses to this work, but I see these reports, despite their matter-of-fact understatement, as an extraordinary reminder of what well intentioned science, collaborating with medicine, can do to improve the lives of human beings.”

    Mr Stuart Lavery, Divisional Clinical Director Women’s Health and Consultant in Reproductive Medicine/Honorary Associate Professor, University College Hospitals NHS Foundation Trust, said:

    “The concept of nuclear transfer has attracted much commentary and occasionally concern and anxiety.

    “The Newcastle team have demonstrated that it can be used in a clinically effective and ethically acceptable way to prevent disease and suffering.

    “The HFEA has shown that regulation need not always be restrictive, and that permissive regulation can lead to innovation at the highest level, allowing scientists to push boundaries, patients to be successfully treated and the public to be reassured.

    “This truly represents the very best of British science and regulation.”

    Prof Bert Smeets, Professor in Clinical Genomics with focus on Mitochondrial Diseases, said:

    “These are papers, the scientific community has waited for, for a long time, as they describe the experience of the Newcastle team on pronuclear transfer to prevent the transmission of mtDNA disease, for which they got approval in 2017. The papers describe the current experience in PNT and PGT for preventing the transmission of mtDNA disease. It is good to present a reproductive care pathway, although it is not fully complete and some of the criteria might be reevaluated based on the presented data. The care pathway starts with carriers of mtDNA mutations. I would also include women who have affected children with de novo mtDNA mutations. This concerns about 25% of the mtDNA patients. The recurrence risk is low and generally prenatal diagnosis is offered for reassurance. Furthermore, women with a very low mtDNA mutation load, with skewing mtDNA mutations or large scale deletions could also opt for prenatal diagnosis. For a reproductive care pathway for mtDNA disease, these groups should be included as well. It is clear that for the remainder according to the HFEA guidelines PNT should only be offered if PGT is unsuitable. It is great that the PNT as an addition to the reproductive choices for mtDNA disease seems to deliver as 8 children without the mtDNA condition were born. However, there are still concerns, as 2 PNT children had a higher mutation load than the carry-over, which means that reversal can occur and could be a risk for having affected children in future treatments. Also, two children had rare medical complications, which according to the authors were not related to the treatment, as this would then be expected for all of them. I do not think that is true as technical variation occurs and donors will be different. It is good to carefully monitor this, as one of the aims of HFEA guided clinical application is to find-out if PNT by itself is safe, not only to prevent mtDNA disease. The discussion on this is not very strong. Finally, a key unanswered question is why it took so long to come out with these results. Eight births with no mtDNA disease in 7 years deviates largely from the expected150 yearly births, as described by the same group in NEJM in 2015, if all women would opt for this procedure. It seems that the children born are quite recent (only one >18 months), so one wonders if there is a learning curve, change in procedure or whatsoever, explaining the increasing success rate. It would be fair to discuss this in more detail as it would make it much clearer and more realistic which women of the target group will benefit from MD. And that is still a positive message.”

    Comments on the broader story:

    Kevin McEleny, Chair, British Fertility Society, said:

    “These landmark papers provide compelling evidence that mitochondrial donation through pronuclear transfer can massively reduce the transmission of pathogenic mitochondrial DNA variants and are a terrific example of how a regulatory framework can be adapted to permit world-leading scientific discovery. Although the number of babies conceived through this novel treatment is small and their long-term follow-up will be required, the study provides hope to people affected by mitochondrial DNA disease and their loved ones.”

    Sarah Norcross, Director of the Progress Educational Trust (PET), said:

    “We could not be more delighted by the news that eight babies with donated mitochondria have been born in the UK, and that all of these children have made normal developmental progress.

    “Our charity spent many years campaigning for UK law to be changed, to permit the use of mitochondrial donation in treatment. We salute the patients who had the courage to attempt these novel treatments, and we thank the team at Newcastle for justifying patients’ confidence in them.

    “Mitochondrial donation will not necessarily be appropriate for every patient who carries disease-causing mitochondrial DNA mutations – rather, its appropriateness depends on various factors that are explored in detail in the new studies. Importantly, the studies place mitochondrial donation within the context of a broader NHS care pathway, that offers a variety of options for people carrying mitochondrial DNA mutations who wish to have children.

    “Nonetheless, the studies demonstrate that mitochondrial donation is a feasible option – indeed, a positive reproductive choice – for some patients. An important consideration is that women considering mitochondrial donation are advised to start their fact-finding early, because of the decline of egg quality with age.

    “The medical and scientific work at Newcastle, and the policy and legal work that preceded it, have set a high standard for introducing new reproductive technology in a careful and scrupulously regulated way. We are pleased to see that Australia is following a similarly responsible path, having recently introduced its own law that permits the use of mitochondrial donation for the purpose of avoiding mitochondrial disease.

    “The work at Newcastle will no doubt inform – and in future, will perhaps also be informed by – the mitoHOPE pilot programme for mitochondrial donation in Australia.”

    Nick Meade, Chief Executive Genetic Alliance, said:

    “Most rare conditions do not yet have a cure or treatment, so for families affected, reproductive choice techniques are the only opportunities to take control of the impact of the condition. For serious conditions caused by nuclear DNA, these opportunities have existed for many years (through preimplantation genetic testing), with today’s news, we know more families have that opportunity now. These techniques have the potential to work for hundreds of conditions caused by mitochondrial DNA, and they are an example of how innovative research can be applied to take steps forward for multiple rare conditions in parallel. With more than 7,000 rare conditions affecting people in the UK, we need this kind of progress.”

    Beth Thompson, Executive Director for Policy & Partnerships at Wellcome, said:  

    “This is a remarkable scientific achievement, which has been years in the making and we are overjoyed for the families of the eight children born so far.  

    “The pioneering work behind mitochondrial donation is a powerful example of how discovery research can change lives. The UK has led the way and has demonstrated the importance of science grounded in close and careful co-ordination between researchers, funders and regulators – and, very importantly, working closely with families affected. 

    “Wellcome has proudly supported this work since the earliest days, including advocating for legislation and licensing. As the science progresses, we will continue championing brave investment in science and for policy and regulation to keep pace. The success of this research should inspire us move forward on other updates, opening the way for further innovation. The groundwork for review of Human Fertilisation and Embryology Act, for example, has been done, it now needs to move forward. We must ensure the UK stays a world leader in life sciences.” 

    Danielle Hamm, Director of the Nuffield Council on Bioethics, said:

    “Today we have seen the first evidence that for a small number of UK families the use of pronuclear transfer (PNT) to prevent the transfer of maternally inherited mitochondrial DNA disorders has resulted in what everyone hoped it would: children who are thriving and appear free of the devastating symptoms of mitochondrial disease.

    “The Nuffield Council on Bioethics’ landmark ethical review of techniques for the prevention of maternally inherited mitochondrial disorders has been instrumental in creating the right regulatory environment to allow this innovative treatment to reach the clinic and change lives for the better.

    “The HFEA’s licensing conditions followed our recommendation and ensured that PNT is only available through a specialist centre. The establishment of the NHS Highly Specialised Mitochondrial Reproductive Care Pathway has ensured that families referred to the service are fully supported and have access to appropriate information, and that long term follow up of participants has been secured.

    “We welcome this great progress, but continued follow-up is crucially important to inform our understanding of the long-term efficacy of the treatment.”

    Peter Thompson, Chief Executive of the HFEA, said:

    “Ten years ago, the UK was the first country in the world to licence mitochondrial donation treatment to avoid passing the condition to children. For the first time, families with severe inherited mitochondrial illness have the possibility of a healthy child. Although it’s still early days, it is wonderful news that mitochondrial donation treatment has led to eight babies being born.

    “Only people who are at a very high risk of passing a serious mitochondrial disease onto their children are eligible for this treatment in the UK, and every application for mitochondrial donation treatment is individually assessed in accordance with the law. These robust but flexible regulatory processes allow the technique to be used safely for the purposes that Parliament agreed in 2015.”

    Prof Frances Flinter, Chair of the HFEA’s Statutory Approvals Committee, said:

    “We are pleased to see the peer-reviewed papers published in the New England Journal of Medicine that explain what has happened to those patients who the HFEA authorised to have mitochondrial donation treatment at the Newcastle Centre at Life. These are patients for whom there was no other option to have a healthy baby who is genetically related to them, and we are delighted for those families.

    “The HFEA will continue to oversee the safe use of mitochondrial donation treatment and assess each application as families come through the programme. These results are testimony to how the UK continues to be a world leader in the use of new medical techniques to change lives.”

    Comment from the editor of the journal the papers are published in (so NOT third party):

    Eric Rubin, MD, PhD, Editor-in-Chief, The New England Journal of Medicine, said:

    “These studies unite scientific rigor, clinical innovation, and deep ethical reflection to illustrate the full research continuum from bench to bedside. At the New England Journal of Medicine, we chose to publish this work in its full context, not only to highlight the outcomes, but also to surface the critical questions it raises about translating breakthroughs into patient care. Where allowed by government regulations, this research has the potential to prevent serious inherited disease and gives parents truly meaningful new options for their children. Its publication also reminds us that preserving the infrastructure and integrity of biomedical research in the U.S. and around the world is essential if we are to continue delivering such transformative treatments to patients.”

    Comments via colleagues at other international SMCs:

    Prof. Dr. Marcus Deschauer, Head of the Working Group on Rare Hereditary Neurological Diseases and Senior Physician at the Clinic and Polyclinic for Neurology, Klinikum rechts der Isar, Technical University of Munich (TUM), said:

    “To my knowledge, this is the first publication of a larger cohort of families/mothers with mitochondrial DNA (mtDNA) disorders who have given birth to children after pre-implantation genetic diagnosis or mitochondrial donation. The work is therefore very important for assessing the effectiveness and risks of these methods in practice.”

    “Per se, the study includes well-studied families with reliable data, but it was not possible to prevent the transmission of the disease-causing mtDNA variants in all families.””A certain carry-over of mtDNA with a disease-causing variant occurs during pre-cell nucleus transfer. It cannot be ruled out that the proportion of mutated mtDNA will continue to increase over the course of a lifetime after carry-over. However, this is unlikely: for example, in patients with the m.3243A>G variant, the degree of heteroplasmy in the blood decreases over the course of life.“

    ”The follow-up periods are not yet sufficient to assess the risks of later disease. Manifestation of an mtDNA disease at a later stage is conceivable in children.””A pathological mtDNA variant is identified in women who can pass it on by means of molecular genetic testing if the woman has symptoms of a mitochondriopathy. There are also cases in which molecular genetic diagnostics are performed for another indication – such as the search for another genetic disease – and a pathological mtDNA is detected. However, according to the ACMG recommendations, this should not be disclosed by genetic laboratories.“

    ”Until now, the lack of data has made it difficult to advise women with mitochondrial diseases on their desire to have children. The DGN guideline ‘Mitochondrial Diseases’ states: ‘Human genetic counselling is particularly complex when it comes to the desire to have children. Prenatal diagnosis can be routinely performed for nuclear mutations, but is more limited for mutations of mitochondrial DNA. The data on preimplantation diagnosis as a means of preventing or reducing the risk of inheritance of pathogenic mitochondrial DNA mutations is extremely limited, and the method is subject to the Preimplantation Diagnosis Ordinance in Germany. These two studies from Newcastle are helpful for counselling.“

    ”Whether a woman with mtDNA disease can expect an uncomplicated pregnancy also depends on the manifestation/severity of the woman’s disease. In cases of significant muscle weakness (including respiratory muscle weakness), this may increase during pregnancy. Natural childbirth may be difficult, making a caesarean section necessary.”

    “If the mitochondrial donation procedure were also permitted in Germany, this would be an option for selected women with an mtDNA disease to significantly reduce the risk of passing on a disease-causing mtDNA variant with a heteroplasmy level above a disease-causing threshold. This would increase the chances of healthy children for families.”

    “However, the data from Newcastle do not suggest that the methods used can guarantee that the disease will not be passed on. In some mtDNA variants, the severity of the disease clearly depends on the degree of heteroplasmy in the blood, so that a reduction in the degree of heteroplasmy in such cases could lead to a milder form of the disease in children.”

    “In the short term, there are no good therapeutic methods for treating mtDNA diseases, so preventing the transmission of mtDNA diseases is the better option. I also consider it difficult to successfully treat children who have inherited an mtDNA variant in the medium term, as gene therapy must reach the DNA in the mitochondria. There is the example of 5q-associated spinal muscular atrophy, in which infants diagnosed in newborn screening can be treated very successfully. Unfortunately, this is not expected to be the case for mtDNA diseases in the near future.””I consider it unlikely that the two children who were symptomatic have a maternally inherited mitochondriopathy. In the case of the child with epilepsy, I would even classify this as very unlikely. I consider the authors’ assessment that the reproductive technology procedure itself or pregnancy complications or metabolic disorders in the mother may be responsible for the symptoms of the two children to be plausible.”

     

    Nuno Costa-Borges, researcher and embryologist, scientific director and CEO of Embryotools, Barcelona Science Park, says:

    “As a pioneering center in mitochondrial replacement therapies (MRT), Embryotools welcomes the recent publication by Hyslop et al. in The New England Journal of Medicine, reporting outcomes from pronuclear transfer (PNT) to prevent the transmission of mitochondrial DNA (mtDNA) disease. The study reports the birth of eight babies—four girls and four boys, including one set of identical twins—born to seven women at high risk of transmitting severe mtDNA disorders. Importantly, all infants are healthy and show no signs of mitochondrial disease. However, the detection of low-level postnatal mtDNA heteroplasmy (“reversal”) in 3 of the 8 infants (5%–16%) deserves particular discussion.

    “Due to UK regulations that prohibit testing for heteroplasmy in embryos, the timing of this reversal could not be pinpointed. Their analysis relied on arrested embryos and blood samples from newborns, which limits interpretation. In contrast, our recent pilot trial using maternal spindle transfer (MST)—a form of MRT where mitochondrial replacement occurs in the oocyte before fertilization—in infertile patients led to seven live births, two of which also showed reversal, a comparable frequency. However, our approach included direct assessment of heteroplasmy in blastocysts and, longitudinally, in multiple tissues including amniotic fluid. This allowed us to accurately define that reversal occurred between the blastocyst stage and mid-gestation (~15 weeks), reinforcing the importance of prenatal testing to detect reversal early and guide clinical decision-making. In our study, all infants are also healthy and have been followed up showing no adverse events.

    “This phenomenon—mtDNA ‘reversal’—has previously been described in human cells in vitro but not in MRT-derived children. Minimal levels of maternal mtDNA carryover can expand substantially, potentially compromising the efficacy of MRTs to prevent mitochondrial disease. The biological mechanisms underlying this selective amplification remain unclear but appear to occur early in development, and instances may therefore be detectable using prenatal testing. It is worth noting that the impact of mtDNA reversal in infertility treatments is likely less concerning, as maternal mtDNA in these cases does not carry pathogenic mutations. Moreover, with appropriate matching of mtDNA haplotypes between the mother and donor, the biological consequences of low-level heteroplasmy could be further minimized or even rendered clinically irrelevant.

    “Currently, only the UK and Australia have regulated the use of MRT to prevent transmission of mtDNA mutations. We believe that other countries should adopt similar regulatory models. In particular, MRT should also be contemplated for infertility treatment. Infertility is a disease recognized by the WHO, and MRT can offer a genetic link to the mother for patients who would otherwise rely on egg donation. This justification aligns with the ethical principles underpinning MRT for disease prevention. As a pioneer group in this technology, Spain should lead in regulating these applications to ensure patient safety and prevent reproductive tourism to countries where such techniques may be offered without appropriate oversight.

    “In light of these findings, we reaffirm the urgent need to continue performing well-regulated, larger, long-term studies to fully evaluate the safety, efficacy, and clinical implications of MRTs. Ongoing research under appropriate oversight is essential to ensure the responsible development of these technologies, improve genetic counseling, and support informed decision-making by patients and clinicians alike.

    “We also advocate for thoughtful regulatory evolution that upholds patient autonomy, scientific excellence, and the principle of reproductive justice.”

    Dr. Dunja M. Baston-Büst, Deputy Head of the IVF Laboratory, UniCareD Cryobank, and UniKiD Research, University Hospital Düsseldorf, Germany, said:

    “Since there are currently no curative therapies for mitochondrial diseases, advances in assisted reproductive technology open up new possibilities for reducing the transmission of such variants. Preimplantation genetic diagnosis, which is commonly used to detect defects in nuclear DNA, can also be used to identify embryos with a low proportion of maternal pathogenic mitochondrial DNA variants, thereby reducing the risk of disease.

    “The replacement of the donor’s zygote pronuclei with the patient’s pronuclei was successful in 127 of 160 cases (79.4 per cent). Of the 127 embryos resulting from this, 122 (96.1 per cent) were still intact on the following day (day 1). The number of intact zygotes per pre-nuclear transfer performed (33 procedures in total) ranged from zero to seven.

    “In 37 of the 39 patients (95 per cent) in the preimplantation diagnosis group, the embryos were assessed on the third day after intracytoplasmic sperm injection (ICSI). For preimplantation diagnosis, a blastomere was biopsied on day three of embryonic development and transfer was usually performed in the fresh cycle after analysis of the mitochondrial DNA from the blastomere.

    “Implementation in Germany is not possible under the current legal requirements (Embryo Protection Act), as egg donation is prohibited.

    “The earlier and more severe a mitochondrial disease occurs, the earlier patients can be identified. Patients in Germany receive comprehensive human genetic or interdisciplinary counselling in accordance with the current S1 guideline ‘Mitochondrial Diseases’. A decision regarding the options for reproductive measures and possible preimplantation diagnosis is made in consultation with the patients and depending on the degree of heteroplasmy. Pre-implantation genetic screening is not possible in Germany due to the ban on egg donation. The alternatives are egg donation abroad or adoption.

    “A patient registry for mitochondrial diseases was established in Germany in 2009. It would be beneficial for reproductive medicine if reproductive outcomes were also collected there, or analysis results if preimplantation diagnosis was performed. Unfortunately, there is no cross-linking between the registries.
    “Furthermore, the search for biomarkers is generally supported in Germany in order to increase the diagnostic accuracy for mitochondrial diseases.

    “For reproductive medicine, I currently see no application of the technology presented in the study in Germany without a comprehensive revision of the Embryo Protection Act and the legalization of egg donation.

    “The new EU SOHO Regulation will come into force in the next few years. Its main purpose is to provide greater protection for the genetic background of children born from egg and sperm donation (in addition to the amendments to the sperm donation register), so that many questions will still arise in the case of three-parent constellations.

    “In mitochondrial donation using pre-nucleation transfer, the nuclear genome is transferred from a fertilized egg cell of the affected woman to an enucleated, fertilized egg cell from a healthy donor. The pronuclei are removed individually from the patients’ zygotes and, after brief treatment with a fusion agent (haemagglutinating virus from the Japanese shell), are placed together under the zona pellucida (protective shell around the egg cell; editor’s note) of the enucleated donor egg cell. Based on findings from preclinical studies, it is standard practice to freeze (vitrify) the eggs of patients for whom pre-nuclear transfer is planned, as donor eggs are not always available at the same time and in sufficient quantities.

    “Pathological variants of mitochondrial DNA can be either homoplasmic (present in all mitochondrial DNA copies) or heteroplasmic (present in only some of the copies). Homoplasmic variants are passed on completely to all offspring, but their expression (penetrance) can vary from individual to individual.

    “Clinical pregnancies were confirmed in eight of 22 patients (36 per cent) who underwent intracytoplasmic sperm injection (ICSI) as part of preimplantation genetic testing, and in 16 of 39 patients (41 per cent) who underwent ICSI as part of preimplantation genetic diagnosis (PGD). Pronuclear transfer resulted in eight live births and one ongoing pregnancy. PGD resulted in 18 live births.

    “Heteroplasmy levels in the blood of the eight infants after pronuclear transfer ranged from undetectable to 16 per cent. Compared to the enucleated zygotes, the proportion of diseased maternal mitochondrial DNA was reduced by 95 to 100 percent in six newborns and by 77 to 88 per cent in two newborns. Heteroplasmy data were also available for ten of the 18 infants after preimplantation genetic diagnosis, with values ranging from undetectable to seven percent.

    “For reasons that are still unclear, the small amount of transferred maternal mitochondrial DNA can rise to homoplasmic levels in about 20 per cent of embryonic stem cell lines derived from embryos after mitochondrial donation. In addition, one in six infants born after maternal spindle transfer for the treatment of infertility had elevated heteroplasmy levels (40 to 60 per cent) of maternal mtDNA. These observations raise the question of whether mitochondrial donation can reliably prevent the transmission of diseased mitochondrial DNA in all cases, especially in homoplasmic variants.

    “Approximately one in 5,000 people develop a mitochondrial disease, making it one of the most common hereditary diseases, although the symptoms can often vary greatly. The symptoms of mitochondrial diseases are very diverse and can affect various organs, for example the muscles with muscle weakness and pain, the nervous system with encephalopathy, epilepsy and neurological disorders, the heart with heart muscle disease, the eyes with blindness and visual impairment, the ears with hearing loss and the endocrine system with diabetes mellitus.

    “Other examples of mitochondriopathies with named syndromes include: autosomal dominant optic atrophy (ADOA) with slowly progressive, usually bilateral, central vision loss; Kearns-Sayre syndrome with cardiac conduction disorders, degenerative changes in the retina, and external ophthalmoplegia; chronic progressive external ophthalmoplegia, which is an incomplete form of Kearns-Sayre syndrome and is characterized by external ophthalmoplegia; MERRF syndrome with cerebellar ataxia, myoclonus, generalized seizures, short stature, and dementia; MELAS syndrome with seizures, dementia, and headaches.

    “In addition to the disease entities listed here, there are a number of other, sometimes very rare syndromes that can be classified as mitochondriopathies but have often been little researched or not yet described.”

    Dr Holger Prokisch, Head of the Mitochondrial Genetics Research Group, Helmholtz Centre Munich – German Research Centre for Health and Environment, Munich, said:“The field of mitochondrial medicine has been eagerly awaiting the results of this study. The robust data describe a real breakthrough for women with a (nearly) homoplasmic pathogenic mitochondrial DNA (mtDNA) variant in terms of their ability to probably have healthy genetically related children. The risk of the children to develop the disease after preimplantation genetic testing is minimal. All gene variants tested require very high heteroplasmy for the disease to manifest, or are typically homoplasmic.“”There is an observation in the literature that in a few cases, the mother’s mutated DNA is revised. Interestingly, this also involves an LHON mutation (Leber’s hereditary optic neuropathy) [3] [4], which is almost always homoplasmic in the population and, according to recent data, has a low penetrance of less than five percent for LHON disease [5] (only five percent of gene carriers also develop the disease; editor’s note). In this respect, the selection of mutation carriers for this study with four LHON mutations is not entirely fortunate. The homoplasmy of the LHON variants suggests that they may offer a selective advantage [6]. Since mitochondrial transfer does not eliminate the mutation, there is a risk that the mutation will be passed on to the next generation. This often leads to significant shifts in heteroplasmy, sometimes to the detriment of patients. However, disease-causing variants tend to have a selection pressure [6].“Human studies show no risk of incompatibility between the donor mtDNA and the parents’ nuclear DNA.””There is no newborn screening for mitochondrial DNA mutations. Women are identified as mutation carriers when they or one of their children develop the disease. Prediction or risk assessment for the next generation is difficult for mtDNA mutations in the mother. Many centers for mitochondrial diseases work with the group in Newcastle to provide information about the options available there or to offer preimplantation genetic diagnosis.”[3] Hudson G et al. (2019): Reversion after replacement of mitochondrial DNA. Nature. DOI: 10.1038/s41586-019-1623-3.
    [4] Kang E et al. (2016): Mitochondrial replacement in human oocytes carrying pathogenic mitochondrial DNA mutations. Nature. DOI: 10.1038/nature20592.
    [5] Mackey DA et al. (2022): Is the disease risk and penetrance in Leber hereditary optic neuropathy actually low?. The American Journal of Human Genetics. DOI: 10.1016/j.ajhg.2022.11.014.
    [6] Kotrys AV et al. (2024): Single-cell analysis reveals context-dependent, cell-level selection of mtDNA. Nature. DOI: 10.1038/s41586-024-07332-0.

    Prof. Dr. Nils-Göran Larsson, Group Leader “Maintenance and expression of mtDNA in disease and ageing”, Department of Medical Biochemistry and Biophysics, Karolinska-Institut, Stockholm, Schweden, said:
    “The study in NEJM is very important and represents a breakthrough in mitochondrial medicine. It should be remembered mitochondrial diseases can be devastating and cause substantial suffering in affected children, sometimes leading to an early death. Families are profoundly affected and the paper in NEJM describe how birth of affected children can be prevented by mitochondrial donation.

    “This advanced procedure is not a disease-treatment but rather an intervention that minimizes the transmission of mutated mtDNA from mother to child. For affected families this is a very important reproductive option. The paper describes a relatively small series of 8 babies born after mitochondrial donation by pronuclear transfer. The paper is carefully done and of very high quality but as always in science the results need to be confirmed by independent studies. Also, long-term clinical follow-up studies of born babies will give additional information about the safety and efficacy of mitochondrial donation.”

    “Before this procedure was applied to human reproduction there was a very long development and evaluation process. There has been a lot of constructive discussion in the scientific community, and the UK Parliament approved legislation allowing mitochondrial donation in 2015.”

    “Mitochondrial donation by the pronuclear transfer procedure always leads to carry-over of some mitochondria from the mother and mutant mtDNA can be transferred. The data presented in the NEJM paper shows that mutant mtDNA was not detected in blood of 5 of the born children. However, in three children, low levels of mutant mtDNA were detected in blood. These low levels of mutant mtDNA are unlikely to cause mitochondrial disease but additional follow-up studies are needed. As pointed out by the authors, the mitochondrial donation by pronuclear transfer should be regarded as a risk-reduction strategy. As always, when it comes to new medical procedures there is a need for validation by independent studies. Also, additional long-term follow-up studies of children born after mitochondrial donation will be needed.”

    “The authors report that the transferred mtDNA has no mutations and the donor mtDNA is therefore unlikely to cause disease or impact ageing. During normal ageing, mtDNA acquires mutations (somatic mutations), e.g., during the massive cell division when the embryo is formed and develops. These mutations are typically present at low levels but accumulate to high levels in a subset of cells in many different ageing tissues. The mitochondrial donation involves transfer of mtDNA without mutations and there is no reason to believe that the donor mtDNA will additionally impact the ageing process.”

    “When it comes disease-causing mtDNA mutations that are present in all copies (i.e., homoplasmic mtDNA mutations) there is currently no alternative to mitochondrial donation to prevent transmission of mutated mtDNA from mother to child. It is possible that alternate methods will be available in the future, e.g., correction of mutant mtDNA by gene editing techniques. There are currently a few promising pharmacological therapies for mitochondrial disease, e.g., nucleoside therapy for mtDNA depletion disorders. It is likely that more treatments will be available in the near future because this field is rapidly developing.”

    Prof. Dr. Heidi Mertes, Associate Professor in Medical Ethics, Department of Philosophy and Moral Sciences, Ghent University, Belgien, said:

    “I am happy to see that the first results from the Newcastle University group are now finally published, after being granted a license by the HFEA in 2017, and that the eight resulting children are in good health. However, while the results show that the technique is feasible and can lead to a substantial reduction of the mutation load in the resulting children, it also shows that we need to tread very carefully.”

    “In line with previous research by the group of Nuno Costa-Borges [1], this research confirms the possibility of reversal (meaning that although there is only a small fraction of the intended mother’s mitochondrial DNA (mtDNA) in the embryo, this fraction sometimes increases substantially as the foetus develops), which could still result in mitochondrial diseases in the resulting children. Fortunately, preliminary research does indicate that while the mutation loads appear to increase between the embryonic phase and birth, they appear to remain stable after birth.”

    “These are very important results as there was a lot of uncertainty over the safety of MRT. Using PGT when possible and reserving MRT for those cases in which PGT cannot offer a solution was a prudent approach given the experimental nature of MRT. It will be interesting to see more data in the future on whether reversal is more frequent in MRT or PGT, so that the safest procedure can be selected.”

    “Although the heteroplasmy-levels are limited in this study, it does show that reversal is a real danger for the offspring, which can have serious health implications. At least three things follow from this.”

    “First, people entering into this and future clinical trials will need to be extensively counselled that this is not a risk-elimination treatment, but a risk-reduction treatment.”
    “Second, we need more research into the mechanisms that trigger reversal, so that it can be prevented before this technique is implemented in routine care + We need follow-up research in the children born after MRT.”

    “Third, it is important to keep in mind that by framing this as a risk-reduction strategy, we are ignoring the possibility of conceiving through a traditional egg donation procedure. While genetic parenthood is evidently important to many people, the trade-off that we are making here is that between a genetically related child with a high risk of mitochondrial disease (natural conception), a genetically related child with a reduced risk of mitochondrial disease (PGT or MRT) and a non-genetically related child with the near-absence of a risk of mitochondrial disease (through donor conception). If people who would have chosen for donor conception now opt for MRT, this is actually a risk-increasing technology, rather than a risk-reducing one.”

    “This strategy lowers the risk of mitochondrial disorders in the children when the point of comparison is natural reproduction by the parents, but the safest option is still donor conception, which eliminates the risk of passing on the mitochondrial condition, rather than reducing it.”

    “While the donor plays an essential role in the birth of the child, attributing them a parenthood-status based on a small genetic contribution appears unwarranted. At the same time it would be correct to call them a ‘genetic progenitor’ or ‘genetic contributor’.”

    “While the group of Nuno Costa-Borges ([1] [2]) received a lot of backlash for performing their MRT clinical trial in people with repeated IVF failure, rather than people with mitochondrial diseases, we must acknowledge in hindsight that given the phenomenon of reversal, their approach might have been the more prudent one. In their study they observed reversal in one infant going from

    [1] Costa-Borges N et al. (2023): First pilot study of maternal spindle transfer for the treatment of repeated in vitro fertilization failures in couples with idiopathic infertility. Fertility and Sterility. DOI: 10.1016/j.fertnstert.2023.02.008.
    [2] Savash M et al. (2025): Mitochondrial DNA ‘reversal’ is common in children born following meiotic spindle transfer, potentially reducing the efficacy of mitochondrial replacement therapies. Konferenzabstract.

    Prof David Thorburn, co-Group Leader of Brain & Mitochondrial Research at Murdoch Children’s Research Institute and the University of Melbourne, said:

    “Mitochondrial donation was legalised in the UK in 2015 and in Australia in 2022. It was clearly a complex process in the UK to develop the approvals processes, the clinical and lab pathways, cope with delays from COVID and accumulate sufficient outcomes to publish them without impinging on the privacy of the families involved.So it is very exciting to see the first publications describing results for the first 8 babies born in the UK program. The initial results demonstrate that the approach is effective in reducing the risk of having a child with mitochondrial DNA disease for women who are at high risk. For about three quarters of couples participating in the pronuclear transfer method, at least one suitable embryo was generated. About 40% of these couples had a baby and all were healthy and had undetectable or low levels of the abnormal mitochondrial DNA. Three babies had short-term symptoms that resolved and did not appear to relate to mitochondrial disease. All babies are developing normally to date, with the oldest 5 years of age.The studies emphasise that longer-term followup needs to be performed, and the efficiency of the method could be further improved to achieve higher pregnancy rates. They demonstrate the value of offering the program in conjunction with other reproductive options, such as pre-implantation genetic testing, which can be effective in women with lower risk. I regard these results as very encouraging and supporting the ongoing development and use of mitochondrial donation in the UK and Australia.

    Dr Santiago Restrepo Castillo, biomedical engineer and postdoctoral researcher at the University of Texas at Austin (USA), said:

    “Mitochondrial diseases are a group of chronic metabolic disorders that can be fatal. These diseases are caused by mutations in the human genome, which consists of nuclear DNA and mitochondrial DNA. In particular, metabolic disorders caused by mutations in mitochondrial DNA, which affect one in five thousand people, are maternally inherited and currently incurable. In recent years, there have been major advancements in the development of strategies for the treatment or prevention of genetic disorders caused by mutations in nuclear DNA. In contrast, similar strategies for diseases caused by alterations in mitochondrial DNA have remained largely understudied. Aiming to establish a preventive strategy for metabolic diseases caused by mitochondrial DNA mutations, the authors of this pair of studies published in the New England Journal of Medicine developed an integrated program of preimplantation genetic testing and pronuclear transfer (PGT and PNT, respectively). In this program, female patients carrying mitochondrial mutations underwent PGT to identify embryos with low levels of mitochondrial DNA mutations. In cases where an embryo with these characteristics was identified, the embryo was implanted in the patient and the course of the pregnancy was monitored. In addition, in cases where it was not possible to identify embryos with low levels of genetic alterations, the patients underwent PNT, a procedure in which mitochondrial DNA without mutations is obtained from a donor. Encouragingly, through this integrated PGT and PNT program, at the time of publication, the authors have already demonstrated a significant reduction in the maternal transmission of mitochondrial mutations in eight cases. Furthermore, the children born from these cases have shown normal development. In conclusion, this study represents a major advancement in the field of medical genetics and genomics. Understanding the current limitations of mitochondrial gene editing, which would allow genetic alterations to be corrected in different contexts, the authors chose to explore a procedure that cuts the problem off at the root by preventing the transmission of the mutated genetic material. Furthermore, this pair of studies demonstrates clinical benefits in children who, without the integrated PGT and PNT program, would likely have been born with debilitating or fatal genetic mutations. It will be exciting to see if the benefits are maintained over time, and it will be critical to further develop this integrated process to increase its success rates”.

    Prof Lluís Montoliu, Research Professor at the National Biotechnology Centre (CNB-CSIC) and at the CIBERER-ISCIII, Spain, says:

    “In 2016, John Zhang, a specialist doctor at an assisted reproduction clinic in New York called the New Hope Fertility Center, crossed the border into Mexico to perform a procedure that was banned in the US and not yet regulated in Mexico. A couple from Jordan had come to this clinic hoping to have viable offspring. The couple had already had two children who had died from Leigh syndrome, one of several mitochondrial diseases that are often devastating and untreatable. Mitochondria (our energy factories) are usually inherited from the mother, from the egg. The mother had approximately 25% of her mitochondria affected, and these were the ones she had passed on to her two deceased children. Dr. Zhang did not use the procedure pioneered in the UK because of the couple’s Muslim faith, which opposed the destruction of human embryos. Instead, he chose to extract the nucleus from the mother’s egg (actually the metaphase plate, an incomplete nuclear division, which is the stage at which all eggs are ready for fertilization) and transferred it to the egg of another woman (with healthy mitochondria), from which he had also previously removed the nucleus. Once the nucleus from the mother had been transferred to the egg of the second woman, he used this resulting egg to perform in vitro fertilization with sperm from the father to obtain embryos. Dr. Zhang created five embryos in this way, only one of which developed normally, was implanted in the mother’s uterus, and resulted in the birth of a healthy baby. It was the first newborn obtained using the “three-parent technique”: two mothers and one father.

    “In the United Kingdom, the Human Fertilisation and Embryology Authority (HFEA) had approved another procedure in 2015, technically different but also called the “three-parent technique,” to solve problems related to mitochondrial diseases. In this case, the father’s sperm is used to fertilize (through intracytoplasmic sperm injection, ICSI) two eggs, one from the mother carrying the affected mitochondria and one from another woman with healthy mitochondria. After fertilization begins, the two pronuclei (paternal and maternal) that appear temporarily are destined to fuse and form the first nucleus of the zygote. Before this happens, researchers can extract the two pronuclei from the in vitro fertilization between the mother’s egg and the father’s sperm and transfer them to the egg of the woman fertilized by the same sperm from the father, from which the pronuclei will have been previously removed. The result is that the egg with the woman’s healthy mitochondria hosts the two pronuclei of the couple, whose baby will be born without the mitochondrial genetic disease and will be genetically from both the father and the mother. The healthy mitochondria will come from the female donor. In this procedure, which is methodologically somewhat more aggressive than the previous one but less risky, one embryo is destroyed to create another, something that the Muslim couple assisted by Dr. Zhang considered unacceptable. The first baby in the United Kingdom obtained through the authorized British three-parent procedure was born in 2023.

    “Ten years later [after the approval of this technique in the UK], a team of British and Australian doctors and researchers published the results of applying the British “three-parent” technique to 22 women carrying pathogenic mutations in their mitochondria (and therefore at high risk of having children born with these incurable diseases) in the prestigious New England Journal of Medicine (NEJM). Of the 22 women treated, only 8 gave birth (36%), and one more pregnancy is still in progress. The eight babies born are healthy, with no signs or very low levels of affected mitochondria, which are not sufficient to cause the disease. So far, all eight children are doing well. Only a couple of them developed minor clinical problems, initially unrelated to the procedure, which were resolved with treatment or spontaneously. In addition, the researchers applied a second technique (preimplantation genetic testing, or PGT) to women with heteroplasmy (a mixture of healthy and affected mitochondria) to assess the percentage of affected mitochondria in babies obtained through in vitro fertilization and select those with lower values of affected mitochondria. In this case, they obtained 16 pregnancies from 39 women (41%) with the result of 18 babies born with a percentage of affected mitochondria of less than 7%.

    “In Spain, our Law 14/2006 of May 26 on assisted human reproduction techniques does not explicitly refer to this technique (which did not exist when this legislation was passed), so sensu stricto the procedure is neither expressly prohibited nor explicitly authorized in our country. Essentially, it is not regulated. The legal and ethical doubts that remain have so far prevented the three-parent technique from being applied in Spain.However, this new study shows that the technique has a remarkable success rate (36%) that could well be offered to couples in which the mother is a carrier of affected mitochondria to have offspring free from terrible mitochondrial diseases. Personally, I believe that we should allow this technique in our country in assisted reproduction clinics that have adequate training in this sophisticated method of embryo intervention.”

    Dr Paul Wuh-Liang Hwu, Professor, College of Medicine, Pediatrics, National Taiwan University, Taipei, Taiwan / Distinguished Research Fellow, China Medical University Hospital, Taichung, Taiwan, said:

    In this week’s New England Journal of Medicine, two research articles published by groups of researchers from the UK describe the success of mitochondrial donation treatments for mitochondrial DNA (mtDNA) diseases. Each human cell contains a few hundred mitochondria. The mitochondrion is a double membrane-bound organelle, and each mitochondrion contains a few copies of double-stranded, circular DNA molecules of around 16,500 genetic units (base pairs).

    “Mitochondria are responsible for energy (ATP) production, fatty acid oxidation, and some other functions for the cells. Pathological variations or deletions of mitochondrial DNA can impair mitochondrial function, and when the proportion of defective mitochondria (heteroplasmy level) is high, cause serious symptoms involving the brain, muscle, and metabolism. During reproduction, all mitochondria are inherited from the mother (the egg). However, the level of defected mitochondria in offspring can be very different from their mothers, leaving reproduction planning almost impossible.

    “In the two studies, mitochondrial donation by pronuclear transfer (PNT) was conducted to reduce the reproductive risk of women with mitochondrial diseases. Both the mitochondrial donor and patient eggs were fertilized first.
    The nucleus of the donor’s fertilised egg was removed and discarded, leaving behind a fertilised egg without a nucleus but with healthy mitochondria. The nucleus from the patient’s fertilised egg was then transferred into this enucleated donor egg.

    “The PNT zygote was then cultured and implanted to continue pregnancy. All live births were in good health and with low levels of defective mitochondria. PNT has been widely used in animal research and now proved to be safe and efficient in humans. This breakthrough gives a reproductive choice for women affected with mitochondrial diseases, which is very important for the patients and their families. However, this study also broke the ban for continuing pregnancy of genetically manipulated human embryos. One argument is that PNT does not really touch the genetic materials but only provides normal mitochondria. The excellent outcome of this study also eases the concerns of nuclear/mitochondrial genome compatibility and other safety issues. Nevertheless, one may still worry if this technology will be abused to improve human physiological quality, for example, creating a body with more efficient energy production. Then, how about adding a little bit of normal, or good, DNA to the nuclear genome, if we can do that safely?

    “As doctors and researchers who take care of patients with genetic disease, we welcome inventions, including reproduction medicine, that can help patients. Certainly, before the safety of new treatments can be confirmed, they should be used in patients with no other choices, or with a favorable benefit over risk. Recently, gene therapies, including gene editing treatments, are rapidly developing, offering hope to patients who previously have no option for treatment. However, we need to ask people to restrain themselves, not to apply PNT or gene therapy to improve the health of people without a medical condition, but to let these new treatments be developed to rescue lives of patients.”

    Prof Lee Chung-His Professor, Graduate Institute of Health and Biotechnology Law, Taipei Medical University, Taipei, Taiwan, said:

    Pronuclear Transfer Technology: Advancing with Cautious Innovation and International Consensus. While early clinical results show promise in reducing the level of pathogenic mitochondrial  DNA in newborns, the application of Pronuclear transfer (PNT) raises significant ethical and regulatory questions that must be addressed through both national oversight and international dialogue. From a bioethical standpoint, germline modification—defined as altering genetic material in a way that affects future generations—has long been met with caution. This is because it involves irreversible changes to the human genome, with potential consequences not only for the individuals born from such interventions but also for society’s understanding of what it means to be human.

    “Pronuclear transfer, however, occupies a unique space in this debate. It targets mitochondrial DNA, which, although essential for cellular energy production, contributes relatively little to traits traditionally associated with identity, such as physical appearance, personality, or intelligence. Because of this limited influence on key phenotypic characteristics, PNT is viewed by some as an acceptable “ethical testing ground” for germline-level intervention. Rather than resorting to high-risk gene therapy after the onset of a hereditary disease, using PNT technology to reduce the likelihood of disease is a more ethically acceptable option. It provides a possible pathway to explore the responsible use of reproductive technologies without crossing the bright-line boundaries typically drawn around nuclear DNA modification.

    “Nonetheless, mitochondrial DNA modification is not without ethical complexity. Even if its direct functional role is narrower, it still involves heritable changes and the creation of embryos with genetic contributions from three individuals—the intended mother and father, and a mitochondrial donor. This raises questions about identity, kinship, and the rights of the resulting child, especially regarding disclosure and autonomy. Moreover, the long-term health effects of such interventions remain unknown. To prevent a gradual erosion of ethical boundaries, transparent ethical review processes and long-term clinical monitoring must be established as foundational requirements for any country considering the use of PNT.

    “From a clinical perspective, preimplantation genetic testing (PGT) should remain the first-line option for reducing the risk of mitochondrial disease transmission. PGT is a more established and less invasive method that allows for the selection of embryos with minimal or undetectable levels of pathogenic mitochondrial DNA. In many cases, this approach has proven effective and carries fewer biological and ethical uncertainties than PNT. In contrast, PNT is a more complex and experimental procedure that combines nuclear DNA from the parents with mitochondrial DNA from a donor egg, and it may result in lower fertilization rates or higher embryonic loss. Therefore, in keeping with the precautionary principle in bioethics, PNT should be considered only when PGT is not feasible or has been shown to be ineffective.

    “The United Kingdom currently leads in the clinical implementation of PNT, having established a strict licensing and regulatory regime through the Human Fertilisation and Embryology Authority (HFEA). The UK’s model reflects a commitment to enabling scientific advancement while maintaining ethical vigilance. However, reproductive technologies such as PNT are inherently transnational. If only a few countries offer access to such procedures, it may prompt “reproductive tourism”, whereby patients travel abroad to seek unregulated or less strictly governed treatments, potentially undermining safety standards and ethical norms.

    “For this reason, a coordinated international approach is urgently needed. The World Health Organization (WHO) and the World Medical Association (WMA) are well-positioned to initiate global discussions and help formulate shared ethical guidelines and governance frameworks. These discussions should encompass not only scientific and medical dimensions but also social, cultural, and legal implications. Establishing minimum ethical standards and oversight mechanisms will help ensure that the benefits of PNT are pursued responsibly and that global health equity and ethical integrity are preserved.”

    Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease’ by Louise A. Hyslop et al. and ‘Mitochondrial Donation in a Reproductive Care Pathway for mtDNA Disease’ by Robert McFarland et al. was published in The New England Journal of Medicine at 22:00 UK time on Wednesday 16th July. 

    DOI: 10.1056/NEJMoa2415539

    DOI: 10.1056/NEJMoa2503658

    Declared interests

    Dr David J Clancy: No interests to declare

    Prof Joanna Poulton: Nothing to declare

    Prof Dusko Ilic: No conflicts of interest

    Prof Dagan Wells: I don’t think I have any declarations relevant to this.

    Dr Andy Greenfield: Andy was a member of the board of the Human Fertilisation & Embryology Authority (HFEA) from 2009 to 2018; he was a member of its Scientific & Clinical Advances Advisory Committee (SCAAC) and Chair of its Licence Committee. He chaired the 3rd and 4th preclinical scientific reviews of the safety and efficacy of mitochondrial donation, in 2014 and 2016. Andy chairs the Independent Advisory Committee of the MitoHOPE Program in Australia. He is also a member of the board of the Human Tissue Authority (HTA), the Regulatory Horizons Council (RHC), the Advisory Committee on Novel Foods and Processes (ACNFP) and Singapore’s Ministry of Health Regulatory Advisory Panel. Andy’s programme of research in developmental genetics was funded by the Medical Research Council at its Harwell Unit from 1996 to 2021. All opinions expressed are his own and not necessarily shared by any organisations with which he is associated.

    Mr Stuart Lavery: No DOIs

    Prof Bert Smeets: I am scientific advisor for the HFEA on PNT applications.

    Sarah Norcross: PET – https://www.progress.org.uk/ – is a charity that improves choices for people affected by infertility and genetic conditions, and that campaigned for the introduction of the Human Fertilisation and Embryology (Mitochondrial Donation) Regulations 2015 into UK law.

    Beth Thompson: Wellcome funded research into mitochondrial donation and co-funded the clinical trial to assess the safety and effectiveness of the treatment.

    Danielle Hamm: The Nuffield Council on Bioethics conducted an ethical review of new techniques that aim to prevent the transmission of maternally-inherited mitochondrial DNA disorders in 2012. The report and key findings of the review are available here.

    HFEA: As of 1 July 2025, 35 patients have been given approval for mitochondrial donation treatment by the HFEA Statutory Approvals Committee. These decisions are made on an individual case by case basis where there are no other options for the families involved and in strict accordance with the law. The published papers set out that 25 of those patients have undergone pronuclear transfer (mitochondrial donation treatment.)

    Prof. Dr. Marcus Deschauer: “Apart from the fact that I spent six months as a researcher in the Mitochondrial Research Group over 20 years ago and subsequently collaborated with the group on scientific projects, and that I am of course well acquainted with some of the co-authors of the two papers, I have no conflicts of interest.”

    Dr. Dunja M. Baston-Büst: “I have no conflict of interest.”

    Dr Holger Prokisch: “I have no conflicts of interest.”

    Prof. Dr. Nils-Göran Larsson: “I have no conflicts of interest with this work.”

    Prof. Dr. Heidi Mertes: “I have no conflicts of interest.”

    Prof David Thorburn: David has declared he has no financial conflicts of interest and has the following unpaid positions:

    Board Member of the Mito Foundation (the major relevant mito advocacy group) and he played a prominent role in their advocacy for legalising mitochondrial donation in Australia.

    He is also a Member of the MitoHOPE Executive, funded by the Medical Research Future Fund to deliver an Australian clinical trial of mitochondrial donation.

    Dr Santiago Restrepo Castillo: No conflicts of interest

    Prof Lluís Montoliu: He declares that he has no conflicts of interest

    For all other experts, no reply to our request for DOIs was received.

    MIL OSI United Kingdom

  • MIL-Evening Report: The secret stories of trees are written in the knots and swirls of your floorboards. An expert explains how to read them

    Source: The Conversation (Au and NZ) – By Gregory Moore, Senior Research Associate, School of Agriculture, Food and Ecosystem Sciences, The University of Melbourne

    Magda Ehlers/Pexels, CC BY

    Have you ever examined timber floorboards and pondered why they look the way they do? Perhaps you admired the super-fine grain, a stunning red hue or a swirling knot, and wondered how it came to be?

    Or perhaps you don’t know what tree species your floorboards are made from, and how to best look after them?

    Finely polished floorboards reveal detail about the timber that can be much harder to detect in unpolished boards or other sawn timbers.

    “Reading” the knots, stubs and other characteristics of floorboards can reveal what type of tree produced it and how it grew. It can also reveal fascinating details about the lives of the trees they once were.

    Reading floorboards can reveal what type of tree produced it, and how it grew.
    Greta Hoffman/Pexels, CC BY

    Telling soft from hard

    A variety of tree species are used to make timber floors. Hardwood species include the pale cream of Tasmanian oak, the honeyed hues of spotted gum and the deep red of jarrah.

    Other times, softwood such as pine or spruce is used. Such species are often fast-growing, and prized for their availability and affordability.

    Hardwoods are, by definition, flowering trees, while softwoods are from cone-bearing trees. Paradoxically, not all softwoods are soft or hardwoods hard. The balsa tree, for example, is a fast-growing hardwood tree renowned for its soft wood.

    It’s not always easy to tell if a floor is hardwood or softwood, but there are discernible differences in their appearance.

    Softwood such as pine or spruce is often fast-growing.
    Geography Photos/Universal Images Group via Getty Images

    Tales in the grain

    The real differences between softwood and hardwood lie in the anatomy and structure of the “xylem tissues” that make up the wood. These tissues transported water and nutrients from the roots to the rest of the plant when the tree was alive.

    The arrangement of xylem tissue in the tree largely determines the “grain” in your floorboards. The grain is the appearance of wood fibres in the timber. The grain can be straight, wavy or spiralled.

    In floorboards with straight grains, a tree’s growth history may be clear. As a tree trunk grows in diameter, it typically produces a layer of bark on the outside and a lighter layer of xylem tissue on the inside. When a tree is cut horizontally, the growth appears as rings. In a tree cut lengthwise (which happens when floorboards are milled) the growth appears as long lines in the timber.

    If the lines in floorboards are very close together, this indicates the tree grew slowly. Wider lines suggest the tree grew rapidly.

    Vessels in a tree’s xylem transport water from the roots to the rest of the plant. Hardwood tree species tend to have large vessels. This gives hardwood floorboards a coarser-grained and less uniform appearance. In contrast, softwood species such as conifers have smaller, dispersed vessels and produce more fine-grained, smoother timber.

    Close lines in floorboards indicate the tree grew slowly.
    Magda Ehlers/Pexels, CC BY

    Knotty histories

    Knots in floorboards occur when a branch dies or is cut, then tissue grows over the stub. The bigger the missing branch, the more substantial the knot.

    Knots in floorboards can reveal much about the source tree. Pine, for example, often features multiple small knots originating from a common point. This reflects the growth pattern of young plantation pines, where several branches grow out from the trunk at the same height from the ground.

    Often, the distance between knots tells us how quickly the tree grew. The greater the distance between the knots, the faster the tree grew in height.

    Knots in floorboards occur when a branch dies or is cut.
    eminumana/Pexels, CC BY

    Clever chemical defence

    The presence of a tree’s “defence chemicals”, known as polyphenols, can be seen clearly in some floorboards.

    Polyphenols in floorboards sometimes appear as dark brown verging on black.
    Author provided

    Polyphenols protect plants against stressors such as pathogens, drought and UV radiation.

    The chemicals contribute to the red hue in some floorboards. Because polyphenols have a preservative effect, they can also make timber more durable.

    Dark reddish or brown timbers containing a high concentration of polyphenols include mahogany, merbau, red gum, ironbark and conifers such as cedar and cypress.

    In cases where a tree is burnt by fire, or attacked by insects or fungus, it produces a lot of polyphenols at the site of the damage.

    In these cases, the presence of polyphenols in floorboards can be very obvious – sometimes appearing as a section that is dark brown verging on black.

    Keeping your floorboards for longer

    It’s widely known that living trees store carbon, and that this helps limit climate change. It’s less well known that timber floorboards also store carbon. And as long as that timber is preserved – and not destroyed by fire, decay or wood rot – that carbon will stay there.

    If floorboards have to be removed, try to make sure the timber is reused or repurposed into other products.

    And if you are installing a new polished timber floor, or already have one, there are steps you can take to make it last for a long time.

    Softwood boards will benefit from a hard surface coating, especially in high-use areas.

    Reducing the exposure of the floor to bright sunlight can preserve the colour of the floorboards and prolong the life of the coating and the timber itself.

    Large knots in floorboards can twist and start to protrude from the surface. To ensure the floor remains even and safe, and to prevent the board from splitting, secure the knot to a floor joist with a nail or glue.

    And take the time to understand the lessons embedded in your floorboards. They have much to teach us about biology and history, if we take the time to read them.

    Gregory Moore does not work for, consult, own shares in or receive funding from any company or organisation that would benefit from this article, and has disclosed no relevant affiliations beyond their academic appointment.

    ref. The secret stories of trees are written in the knots and swirls of your floorboards. An expert explains how to read them – https://theconversation.com/the-secret-stories-of-trees-are-written-in-the-knots-and-swirls-of-your-floorboards-an-expert-explains-how-to-read-them-250776

    MIL OSI AnalysisEveningReport.nz

  • MIL-OSI Africa: TOP AFRICA NEWS Named Best Environment & Natural Resources News Platform 2025 by MEA Markets

    Source: APO

    TOP AFRICA NEWS (www.TOPAFRICANEWS.com) has been recognized as the Best Environment & Natural Resources News Platform 2025 by MEA Markets, highlighting its significant contribution to environmental journalism across Africa.

    This latest accolade caps a series of distinguished awards for the platform, including SME of the Year (2022), Best International Publication Service Provider (2023), and Best Marketing Service Provider (2024), demonstrating consistent excellence and leadership in the region’s media landscape.

    Founder and Managing Director Mr. DUSABEMUNGU Ange de la Victoire expressed pride in the achievement, stating, “Being named the best platform in this vital field underscores our dedication to covering critical environmental issues affecting Africa. It motivates us to continue delivering impactful, accurate, and insightful journalism that can influence policy and inspire sustainable change across the continent.”

    He emphasized the platform’s mission, saying, “At TOP AFRICA NEWS, our goal remains to amplify Africa’s stories on issues like natural resources, conservation, and sustainable development—topics that are pivotal for the continent’s future. This award reaffirms our role as a trusted voice for Africa’s environment and natural resources sectors.”

    Available on www.TOPAFRICANEWS.com, the website provides comprehensive coverage of topics ranging from agriculture and tourism to youth engagement and peacebuilding, aiming to inform and empower communities across Africa.

    As climate and environmental challenges grow more urgent, TOP AFRICA NEWS pledges to sustain its focus on delivering high-quality news that drives awareness, action, and sustainable development across Africa.

    Distributed by APO Group on behalf of TOP AFRICA NEWS.

    Additional link: https://apo-opa.co/4kHbEw8

    Media contact: 
    vickange@gmail.com  

    About TOP AFRICA NEWS: 
    TOP AFRICA NEWS is a Private shareholder Digital News Website managed by AFRICA NEWS DIGEST Ltd, a Domestic Company registered in Rwanda Development Board. Available on www.TOPAFRICANEWS.com, this website publishes stories from across Africa focusing on Environment, Natural resources, Livestock and Agriculture, Tourism and conservation, Youth, Sports and Culture, Peace Building, Health, Infrastructure and ICT, Security, Education, Business and Banking. The main objective of this website is to tell the World the real Africa’s Story from the real and reliable sources. We Publish News Stories, Supplements stories, advertorials, Feature stories among many others. We are based in Kigali, Rwanda.

    Media files

    .

    MIL OSI Africa

  • MIL-OSI USA: Padilla, Chu, Colleagues Join Union Workers to Announce Legislation to Protect Workers from Extreme Heat

    US Senate News:

    Source: United States Senator Alex Padilla (D-Calif.)

    Padilla, Chu, Colleagues Join Union Workers to Announce Legislation to Protect Workers from Extreme Heat

    WATCH: Padilla pushes for enforceable workplace heat stress protections after hottest year on record

    WASHINGTON, D.C. — Today, on the heels of another harsh heat wave across California, U.S. Senator Alex Padilla (D-Calif.) and Representative Judy Chu (D-Calif.-28) joined union workers from the United Farm Workers (UFW), American Federation of State, County and Municipal Employees, and United Steelworkers to announce their bipartisan, bicameral legislation to implement federal enforceable workplace heat stress protections.

    Co-leads of the legislation include U.S. Senators Edward J. Markey (D-Mass.) and Catherine Cortez Masto (D-Nev.), and Representatives Robert C. “Bobby” Scott (D-Va.-03), Ranking Member of the House Committee on Education and Workforce, and Alma Adams (D-N.C.-12).

    To address the increasing risks from extreme temperatures, the lawmakers introduced the Asunción Valdivia Heat Illness, Injury, and Fatality Prevention Act, legislation to protect the safety and health of indoor and outdoor workers who are exposed to dangerous heat conditions in the workplace. The legislation would protect workers against occupational exposure to excessive heat by requiring the Occupational Safety and Health Administration (OSHA) to establish an enforceable federal standard to protect workers in high-heat environments with commonsense measures like paid breaks in cool spaces, access to water, limitations on time exposed to heat, and emergency response for workers with heat-related illness. The bill also directs employers to provide training for their employees on the risk factors that can lead to heat illness and guidance on the proper procedures for responding to symptoms.

    The bill is named in honor of Asunción Valdivia, who died in 2004 after picking grapes for 10 hours straight in 105-degree temperatures. Mr. Valdivia fell unconscious, but instead of calling an ambulance, his employer told Mr. Valdivia’s son to drive his father home. On his way home, he died of heat stroke at the age of 53.

    “Asunción Valdivia’s death was completely preventable, yet his story is sadly not unique. As the planet continues to grow hotter, there is still no federally enforceable heat safety standard for workers. That’s not just dangerous for the farm workers and construction workers who work all day outside in the sun — it’s also dangerous for the factory and restaurant workers in boiling warehouses and kitchens,” said Senator Padilla. “Every family deserves to know that even on the hottest day, their loved one will come back home. A national heat safety standard would provide that peace of mind and finally give workers the safety they deserve.”

    “Even as heat waves become more frequent, longer-lasting, and more severe, red state politicians are rolling back heat protections and child labor protections across the country. It’s not rocket science—you cannot be pro-worker if you are anti-heat protection,” said Senator Markey. “Our legislation would provide workers with basic, effective protections: access to water, access to shade, time limits on high heat exposure, and procedures for emergency medical response. Every worker deserves to know when they clock in that they will return home safe at the end of their shift.  The thermometer is rising and the clock is ticking. Republicans want to sacrifice working Americans. Let’s save our workers instead.”

    “From farmhands to construction workers, America’s essential workforce is doing important work while under extreme heat conditions,” said Senator Cortez Masto. “Temperatures continue to reach record highs in Nevada and across the United States. We must act now to protect our communities’ vital workers.” 

    “As we continue to experience record-breaking summer heat waves, we’re also seeing a distressing increase in cases of workers collapsing and even losing their lives due to excessive heat. I will never forget people like Asunción Valdivia or Esteban Chavez Jr., who passed away in Pasadena, California in 2022 after a day of delivering packages in 90-degree heat in a truck without air conditioning. Unfortunately, their tragic deaths were entirely preventable,” said Representative Chu. “Whether on a farm, driving a truck, or working in a warehouse, workers like Asunción and Esteban keep our country running while enduring some of the most difficult conditions—often without access to water or rest. To protect our workforce and save lives, we must pass this bill into law and establish comprehensive and enforceable federal standards addressing heat stress on the job.”

    “This summer, Americans across the country are grappling with some of the hottest temperatures on record. Yet workers in this country still have no legal protection against excessive heat—one of the oldest, most serious, and most common workplace hazards. Heat illness affects workers in our nation’s fields, warehouses, and factories, and climate change is making the problem more severe every year,” said Ranking Member Scott, House Committee on Education and Workforce. “This legislation will require OSHA to issue a heat standard on a much faster track than the normal OSHA regulatory process. I was proud to advance this important bill in 2022, and I urge Chairman Walberg and Committee Republicans to do so again this Congress. Workers deserve nothing less, particularly as heat-related illnesses and deaths rise.”

    “As we face record temperatures, it has never been more important that we protect our workers facing extreme heat in the workplace,” said Representative Adams. “Last year, a North Carolina postal worker Wendy Johnson lost her life to heat illness after spending hours in the back of a postal truck on a 95-degree day with no air conditioning. Her death was entirely preventable, and Wendy should still be with us today. I’m proud to introduce this bill so we can honor her memory and ensure every worker has the protections from extreme heat that Wendy deserved.” 

    According to the National Oceanic and Atmospheric Administration (NOAA), 2024 was the warmest year on record for the United States. The past decade, including 2024, was the hottest on record, marking a decade of extreme heat that will only get worse. Heat-related illnesses can cause heat cramps, organ damage, heat exhaustion, stroke, and even death. Between 1992 and 2017, heat stress injuries killed 815 U.S. workers and seriously injured more than 70,000. The Washington Center for Equitable Growth estimates hot temperatures caused at least 360,000 workplace injuries in California from 2001 to 2018, or about 20,000 injuries a year. The failure to implement simple heat safety measures costs U.S. employers nearly $100 billion every year in lost productivity.

    From 2011-2020, heat exposure killed at least 400 workers and caused nearly 34,000 injuries and illnesses resulting in days away from work; both are likely vast underestimates. Farm workers and construction workers suffer the highest incidence of heat illness. And no matter what the weather is outside, workers in factories, commercial kitchens, and other workplaces, including ones where workers must wear personal protective equipment (PPE), can face dangerously high heat conditions all year round.

    The Asunción Valdivia Heat Illness, Injury, and Fatality Prevention Act has the support of a broad coalition of over 250 groups, including: Rural Coalition, International Brotherhood of Teamsters, AFL-CIO, UNITE HERE!, Communication Workers of America, Alianza Nacional de Campesinas, Sierra Club, United Farm Workers, Farmworker Justice, Public Citizen, International Union of Bricklayers and Allied Craftworkers, United Food and Commercial Workers International Union, Union of Concerned Scientists, United Steelworkers, National Resources Defense Council, American Lung Association, and Health Partnerships.

    “Every worker safety rule in America is written in blood,” said UFW President Teresa Romero. “The UFW has been fighting for heat safety protections for decades. Over 20 years later, Asuncion Valdivia’s death still hurts. There are so many other farm workers — many whose names we do not know — who have also been killed by extreme heat on the job in the years since. Enough is enough. Every farm worker deserves access to water, shade, and paid rest breaks — it’s past time for Congress get this done.”

    “Too many workers – including AFSCME members – have lost their lives on the job as a result of blistering heat waves and record-breaking temperatures,” said AFSCME President Lee Saunders. “As the number of heat-related illnesses and fatalities continue to rise, it is well past time we adopt nationwide safeguards to better protect the workers who maintain our infrastructure, keep our streets clean, harvest our food, and keep our economy moving. We at AFSCME thank Senator Padilla and Representative Chu for introducing the Asunción Valdivia Heat Illness, Injury, and Fatality Prevention Act, which will ensure essential workers who brave the heat can do their jobs safely and effectively, and most importantly, make it home alive.”

    “For the Steelworkers Union, we represent workers in manufacturing settings and in a host of other areas where not only is it hot outside, but the areas that they work around are as hot as up to 3,000 degrees and they must wear protective equipment. The Asunción Valdivia Heat, Illness, Injury, and Fatality Prevention Act is important because it will provide a basic standard for not just outdoor, but indoor workplaces as well to ensure that there is proper rest breaks and the ability to stay cool. The Steelworkers are absolutely supportive of this bill and are going to work with Republicans and Democrats to ensure that heat illness is the last thing a worker should worry about,” said Roy Houseman, Legislative Director of United Steelworkers. 

    “Everyone deserves safe working conditions, but powerful corporations have not done enough to protect their workers from hot working environments, exacerbated by the climate crisis,” said Liz Shuler, President of the AFL-CIO. “Extreme heat is increasingly causing indoor and outdoor workers to collapse or even die on the job, and our union family has already lost too many members to preventable, work-related heat illness. The Occupational Safety and Health Administration (OSHA) must issue a strong heat rule, not a weak one, to ensure workers have specific protections they need and to be able to raise unsafe working conditions without fear of retaliation.”

    “It’s long past time for meaningful legislation to protect Teamsters and other workers from the effects of prolonged heat exposure and dangerous heat levels while at work,” said Teamsters General President Sean M. O’Brien. “Paid breaks in cool spaces, access to water, and limitations on time exposed to heat are simple common sense steps that should be mandated immediately. Waiting to implement these measures is unacceptable and will result in the further loss of lives.”

    “Workers in America are facing unprecedented dangers from climate-driven heat and extreme weather, and things are only getting worse. It is far past time for a strong national standard to protect workers from illness and death caused by exposure to extreme heat. The provisions mandated in this bill, including temperature triggers, acclimatization, water, shade and paid rest breaks, would save countless lives. They represent a common sense and common decency approach that employers could quickly adopt. American workers deserve no less, and they urgently need it. Today, OSHA is in the final stage of issuing a final rule on this issue. It is imperative that the rule maintain the integrity and high standards called for in the Asuncíon Valdivia Heat Illness, Injury, and Fatality Prevention Act. We applaud Senators Padilla, Markey, and Cortez Masto and Representatives Chu, Adams, and Scott, as well as the dozens of Senators and Congresspersons who have joined them in this long effort. It’s time to bring a high quality, protective standard to the finish line for American workers,” said Ernesto Archila, Climate and Financial Regulation Policy Director, Public Citizen.

    “Every summer high temperature records get broken in states across the country, and while public health officials urge residents to stay inside and stay safe millions of workers have to report for work. From fields to warehouses, airports to schools, construction sites to manufacturing plants, and many more industries, too many workers are at risk of not getting home safely at the end of the day due to exposure to heat on the job. We know how to prevent these dangers. In fact, both outdoor and indoor workers in states like Oregon, California, and Maryland have strong, enforceable protections in place already. And in Washington, Colorado, and Minnesota at least some categories of workers are being kept safe from heat. But millions labor in other states where there are no protections; worker safety is left to the federal government in these states, and absent strong rules workers are left to protect themselves and hope for the best. We must extend workplace protections from heat to all workers. The National Employment Law Project thanks Senator Padilla and Representative Chu, as well as the dozens of Senators and Congresspersons who have cosponsored the Asunción Valdivia Heat Illness, Injury, and Fatality Prevention Act of 2025,” said Anastasia Christman, Senior Policy Analyst, National Employment Law Project.

    The bill is cosponsored by Senators Angela Alsobrooks (D-Md.), Tammy Baldwin (D-Wis.), Richard Blumenthal (D-Conn.), Lisa Blunt Rochester (D-Del.), Cory Booker (D-N.J.), John Fetterman (D-Pa.), Ruben Gallego (D-Ariz.), Kirsten Gillibrand (D-N.Y.), Martin Heinrich (D-N.M.), Mazie Hirono (D-Hawaii), Mark Kelly (D-Ariz.), Ben Ray Luján (D-N.M.), Jeff Merkley (D-Ore.), Patty Murray (D-Wash.), Jack Reed (D-R.I.), Bernie Sanders (I-Vt.), Brian Schatz (D-Hawaii), Adam Schiff (D-Calif.), Chris Van Hollen (D-Md.), Elizabeth Warren (D-Mass.), Peter Welch (D-Vt.), Sheldon Whitehouse (D-R.I.), and Ron Wyden (D-Ore.).

    Senator Padilla has acted urgently to address the threats posed by extreme heat as the climate crisis becomes more severe. Padilla successfully called on OSHA to establish the first-ever federal safety standard to protect workers from the severe risks of excessive heat, implementing key provisions from the Asunción Valdivia Heat Illness, Injury, and Fatality Prevention Act. Padilla and his colleagues also led 112 members of Congress in calling on the Biden Administration to implement a workplace federal heat standard as quickly as possible. The letter urged OSHA to model the standard after the provisions in the Asunción Valdivia Heat Illness, Injury, and Fatality Prevention Act. Additionally, Padilla and Markey’s Preventing Health Emergencies and Temperature-related (HEAT) Illness and Deaths Act advanced out of the Senate Committee on Commerce, Science, and Transportation last year.

    Padilla previously joined union members and workers from UFW and the Kern, Inyo, and Mono Counties Central Labor Council, AFL-CIO in Forty Acres, California in 2023 to announce his legislation to implement an enforceable federal workplace heat standard.

    A one-pager on the Asunción Valdivia Heat Illness, Injury, and Fatality Prevention Act is available here.

    A section-by-section of the bill is available here.

    Full text of the bill is available here.

    MIL OSI USA News

  • MIL-OSI USA: Senators Rosen, Hyde-Smith, Kelly and Reps. Houlahan, Baird Introduce Bipartisan, Bicameral Legislation to Support Workers Entering or Returning to STEM Careers

    US Senate News:

    Source: United States Senator Jacky Rosen (D-NV)

    Legislation Would Help Businesses Bring On Mid-Career Workers Seeking To Return To Or Transition Into STEM Jobs
    WASHINGTON, DC – Today, U.S. Senators Jacky Rosen (D-NV), Cindy Hyde-Smith (R-MS), and Mark Kelly (D-AZ) introduced the STEM Restoring Employment Skills through Targeted Assistance, Re-entry, and Training (RESTART) Act. This bipartisan legislation would provide funding to support mid-career internships, known as “returnships,” for workers seeking to return to or transition into the STEM workforce. Representatives Chrissy Houlahan (D-PA) and Jim Baird (R-IN) have also introduced identical bipartisan legislation in the U.S. House of Representatives.
    “When we invest in STEM education and workforce development, we can open the door to successful careers in some of the most in-demand industries,” said Senator Rosen. “I’m glad to introduce this bipartisan bill to help give workers the training and tools they need to enter new STEM careers. I’ll keep working across party lines to make sure all Nevadans have the skills needed to fill good-paying jobs.” 
    “Many skilled professionals step away from the workforce, but face significant barriers when trying to return, especially in technical fields where innovation moves fast,” said Senator Hyde-Smith. “Our legislation equips small and mid-sized businesses with the tools to tap into this valuable talent pool.  This will help hardworking Americans reconnect with meaningful careers while growing the STEM workforce in states like Mississippi and beyond.”
    “Arizona’s 21st century economy depends on a strong STEM workforce, and that means making sure talented workers who’ve taken time away or are looking to transition into STEM fields have a real pathway back in,” said Senator Kelly. “This effort will help small businesses tap into an underutilized talent pool while giving Arizonans the support they need to reenter the workforce and succeed in high-paying careers.”
    “As a former Air Force engineer and chemistry teacher, I know that building a strong STEM workforce is essential not only for creating good-paying jobs, but also for safeguarding our national security,” said Representative Houlahan. “Whether it’s biotechnology, quantum computing, or clean energy, the global race for innovation is accelerating, and we can’t afford to leave talent on the sidelines. The bipartisan STEM RESTART Act will help mid-career professionals and those returning to the workforce enter high-demand STEM fields so we can strengthen our economy, compete globally, and protect America’s leadership in emerging technologies. I’m proud to reintroduce this commonsense legislation, which is a win for both businesses and workers across our Commonwealth and country.”
    “If we want to maintain our global competitive edge and continue to lead the world in innovation, we must ensure we have a well-equipped STEM workforce now and empower future generations in STEM fields,” said Congressman Baird. “A robust STEM workforce is also vital to our economic prosperity and national security, especially when up against the threat of Communist China. I thank my colleagues in the House and Senate for their work on this bipartisan legislation to equip Hoosiers who want to return to the STEM workforce with the tools they need to fill job openings and build the greatest economy in history.”
    “The STEM RESTART Act is a forward-thinking investment in our nation’s workforce,” said Chris Heavey, Interim President of the University of Nevada, Las Vegas. “By supporting mid-career professionals reentering the STEM fields, this bill strengthens innovation, expands opportunity, and ensures that talent and experience are not left behind.”
    “The Society of Women Engineers is thrilled to see the STEM RESTART Act reintroduced in 2025. As the nation continues to rebuild a strong and inclusive STEM workforce, this legislation is more critical than ever. Hundreds of thousands of STEM professionals have stepped away from technical careers in recent years, and research shows most want to return—but face steep barriers. Grants for structured ‘returnships’ give mid-career professionals real, paid pathways back into meaningful STEM roles,” said Karen Horting, Executive Director & CEO of the Society of Women Engineers. “SWE and our 50,000 plus members fully support this bipartisan, bicameral effort to bridge talent gaps, bolster small and midsize businesses, and drive innovation. We urge lawmakers to pass the STEM RESTART Act as soon as possible and reaffirm our collective commitment to supporting women and others who pause their careers, as well as the country’s economic growth and global competitiveness.”
    The STEM RESTART Act has been endorsed by the Society of Women Engineers, STEM Education Coalition, AnitaB.org, Nevada System of Higher Education, College of Southern Nevada, Vegas Chamber, Henderson Chamber of Commerce, Nevada State University, and University of Nevada, Las Vegas.
    Senator Rosen has been a leader in advocating for tech innovation and improving access to STEM careers. She helped pass the bipartisan CHIPS and Science Act, which invests $52 billion in domestic computer chip manufacturing to help address the current shortage. Additionally, Rosen helped write the broadband section of the Bipartisan Infrastructure Law, which is delivering $65 billion to make high-speed internet more available and affordable to Americans. In 2020, Senator Rosen’s bipartisan Building Blocks of STEM Act, which breaks down barriers to allow more young girls to study computer science, was signed into law.  

    MIL OSI USA News

  • MIL-OSI USA: Rosen, Cortez Masto Demand Trump Administration Release Nearly $7 Billion for K-12 Education

    US Senate News:

    Source: United States Senator Jacky Rosen (D-NV)

    Washington, DC – U.S. Senators Jacky Rosen (D-NV) and Catherine Cortez Masto (D-NV) joined Senator Ruben Gallego (D-AZ) in a letter to the U.S. Department of Education Secretary Linda McMahon demanding answers over the Trump administration’s decision to withhold nearly $7 billion in federal funding for K-12 public schools, including more than $60 million for schools in Nevada. The Senators urged the Department to restore the funding and provide clarity for schools and educators. On July 1, schools across the country reported they were unable to access their federal funding after the Department of Education abruptly froze nearly $7 billion in grants, even though the funds were appropriated by Congress and already factored into school budgets. In Nevada, affected programs include after-school programs, English-learner services, professional development, and migrant education. At least fourteen percent of Nevada students are English-Language Learners.
    “These funds, which represent longstanding investments in K–12 education, support a wide range of priorities such as teacher recruitment, after-school programs, English learner instruction, school-based mental health services, and academic enrichment,” the Senators wrote. “Withholding funds for these important programs will disrupt essential services and undermine the support structures that students, families, and educators rely on every day.”
    Read the full letter HERE.
    Senator Rosen has been forcefully pushing back on Donald Trump’s attempt to dismantle public education. She spoke out against President Trump’s plan to dismantle the Department of Education, calling it “an illegal, irresponsible attack on students and families.” She also recently joined an amicus brief against the unconstitutional dismantling of the Department, warning of its harmful impact on Nevada schools. In April, Senator Rosen condemned the Trump Administration’s proposal to eliminate Head Start funding, calling the cuts “outrageous and cruel” and pledging to defend early childhood education programs that help Nevada families thrive.

    MIL OSI USA News