Category: COVID-19 Vaccine

  • MIL-OSI: CD47 Targeted Cancer Immunotherapy Drugs Clinical Trials FDA Approval Insight

    Source: GlobeNewswire (MIL-OSI)

    Delhi, Sept. 26, 2024 (GLOBE NEWSWIRE) — Global CD47 Inhibitor Drug Clinical Trials Insight & Market Opportunity Outlook 2028 Report Highlights

    • Global & Regional Market Opportunity Outlook
    • Insight On More Than 100 CD47 Inhibitor Drugs In Clinical Trials
    • Global CD47 Inhibitors Clinical Trials Insight By Company, Country, Indication & Phase
    • Orphan, Fast Track, Breakthrough Therapy Designation Insight
    • Key Drugs Initiation & Completion Year
    • CD47 Clinical Application & Development Outlook By Indication
    • CD47 Inhibitor Drugs Clinical Developments & Trends By Country
    • Global CD47 Inhibitor Drug Market Dynamics

    Download Report:

    https://www.kuickresearch.com/report-cd47-antibody-cd47-inhibitor-cd47-function-cd47-expression-cd47-t-cells-cd47-marker-anti-cd47-antibody

    Traditionally, cancer management has primarily relied on surgery, radiation therapy, and chemotherapy. While these treatments have demonstrated significant efficacy in eradicating primary tumors, they are accompanied by systemic toxicities and high rates of relapse, which represent major limitations. The increasing prevalence of cancer and the shortcomings of conventional therapies have driven the demand for novel targeted therapies that can address these limitations while enhancing specificity and targeting capabilities against the disease. One such innovative approach involves targeting the CD47 surface checkpoint, which can inhibit cancer proliferation.

    Cancer immunotherapy has emerged as a promising strategy capable of overcoming the challenges associated with traditional cancer treatments. This novel therapy aims to harness the immune system’s ability to recognize, target, and destroy cancer cells. Preliminary and clinical studies have shown that CD47 proteins are overexpressed in various tumor types. A primary factor contributing to the hallmark characteristics of cancer is the inhibition of macrophage phagocytosis due to the blockade of the CD47/SIRPα interaction, which sends a “don’t eat me” signal to macrophages. Consequently, multiple antibodies targeting the CD47 checkpoint are currently in development to reduce cancer cell proliferation.

    Moreover, CD47-targeted therapies aim to utilize various components of the immune system, acting at different stages of the immune response to enhance the body’s natural defense against target cells. In support of this hypothesis, numerous clinical studies are underway. For example, HX009 is a recombinant humanized anti-CD47/PD-1 bifunctional antibody under development and clinical investigation by Waterstone Hanxbio. An ongoing Phase 1/2 clinical trial is assessing HX009 as a novel treatment for patients advanced solid tumors.

    The therapeutic landscape of immunotherapy now includes a range of agents, such as monoclonal antibodies, immune checkpoint inhibitors, vaccines, antibody-drug conjugates, and more, all aimed at improving outcomes for cancer patients through combination therapies. For example, the novel CD47 inhibitor evorpacept (ALX148) is currently being evaluated in several clinical trials as part of various combination regimens. Specifically, evorpacept is being tested in combination with Cetuximab and Pembrolizumab for the treatment of colorectal cancer, with Venetoclax and Azacitidine for acute myeloid leukemia, and with Rituximab and Lenalidomide for various types of B-cell non-Hodgkin lymphoma.

    Furthermore, regulatory bodies have been supportive towards the growing class of CD47-targeting therapies, as suggested by the recent IND clearances and the awarding of drug designations. FDA granted the fast track designation to PT217, a bispecific antibody targeting CD47 and DLL3, in April 2024, while China’s NMPA also accepted Immuneonco’s clinical trial application to conduct pivotal phase 3 clinical studies for its CD47 inhibitor IMM-01, in combination with the PD-1 Inhibitor tislelizumab. All these factors indicate that the CD47 market is expanding rapidly and is expected to grow further due to the rising incidence of cancer, which is projected to increase in the coming years.

    Additionally, the involvement of multiple pharmaceutical companies in the field of CD47-targeted immunotherapy has spurred growth in clinical research. Various organizations, hospitals, and centers, such as The First Affiliated Hospital of Soochow University, Cancer Hospital Chinese Academy of Medical Sciences, and Zhejiang Cancer Hospital, are conducting clinical trials to address cancer-related ailments.

    In summary, immunotherapy targeting the CD47 protein has emerged as a breakthrough therapy in cancer management, demonstrating promising responses in patients. Although no therapies have yet been approved for the commercial market, several CD47-targeted immunotherapies are anticipated to enter the market soon, driven by a surge in clinical trials and research in this area. Currently, the United States leads the CD47 immunotherapy sector; however, developing countries like China are increasingly engaging in numerous preclinical and clinical studies in this domain, fueled by technological advancements, a rising cancer patient population, and expanding collaborations.

    The MIL Network

  • MIL-OSI USA: HARRISBURG – Shapiro Administration to Encourage Pennsylvanians to Get Updated Vaccines as Respiratory Virus Season Begins

    Source: US State of Pennsylvania

    September 27, 2024Harrisburg, PA

    ADVISORY – HARRISBURG – Shapiro Administration to Encourage Pennsylvanians to Get Updated Vaccines as Respiratory Virus Season Begins

    Pennsylvania Department of Health Secretary Dr. Debra Bogen and Pennsylvania Insurance Department Commissioner Michael Humphreys will join area pharmacists at the See-Right Pharmacy in Harrisburg to stress the importance of getting their annual vaccinations against COVID-19, flu and RSV to safeguard their health as respiratory virus season begins.

    The vaccinations are updated to protect against severe illness from new virus variants circulating in Pennsylvania, and the United States. Health care providers recommend flu and COVID-19 vaccinations for people six months of age and older; older adults and pregnant women are encouraged to get RSV vaccinations.

    Vaccinations are especially important for high-risk groups including people 65 and older, people with certain medical conditions, and people at a higher risk of developing complications from respiratory illness.

    WHO:
    Department of Health Secretary Dr. Debra Bogen
    Pennsylvania Insurance Department Commissioner Michael Humphreys
    Victoria Elliott, RPh, MBA, CAE, CEO of PA Pharmacists Association
    Paul Bowers, PharmD, Pharmacy Manager at See-Right Pharmacy

    WHEN:
    September 27, 2024; 1:00 PM

    WHERE:
    See-Right Pharmacy
    2647 North 6th Street
    Harrisburg, PA 17110

    VISUALS:
    Secretary Bogen and Commissioner Humphreys will receive the updated COVID-19 vaccine as part of the event.

    MEDIA RSVP: Media interested in attending must RSVP with the name of the reporter and photojournalist to ra-dhpressoffice@pa.gov.

    MEDIA CONTACT:
    Mark O’Neill, ra-dhpressoffice@pa.gov
    Diego Sandino, Insurance, ra-in-press@pa.gov

    MIL OSI USA News

  • MIL-OSI USA: FDA Approves New Drug to Treat Niemann-Pick Disease, Type C

    Source: US Department of Health and Human Services – 3

    For Immediate Release:

    Today, the U.S. Food and Drug Administration approved Aqneursa (levacetylleucine) for the treatment of neurological symptoms associated with Niemann-Pick disease type C (NPC) in adults and pediatric patients weighing at least 15 kilograms. 

    “This is the second treatment the FDA has approved for NPC within the span of a week. Today’s action further underscores the agency’s commitment to support development of new treatments for rare diseases,” said Janet Maynard, M.D., M.H.S., director of the Office of Rare Diseases, Pediatrics, Urologic and Reproductive Medicine, in the FDA’s Center for Drug Evaluation and Research. “This approval again demonstrates the FDA’s commitment to work with the scientific community to overcome the unique challenges that may arise with rare disease drug development.”

    NPC is a rare genetic disease that results in progressive neurological symptoms and organ dysfunction. It is caused by changes in either the NPC1 or NPC2 gene, affecting the necessary transport of cholesterol and other lipids within a cell. As a result, these cells do not function as they should, ultimately causing organ damage. On average, individuals affected by this devastating disease only live for about 13 years.

    The safety and efficacy of Aqneursa for the treatment of NPC were evaluated in a randomized, double-blind, placebo-controlled, two-period, 24-week crossover study. The duration was 12 weeks for each treatment period. The study enrolled 60 patients. To be eligible for the study patients had to be 4 years of age or older with a confirmed diagnosis of NPC and at least mild disease-related neurological symptoms. Participants could receive miglustat, an enzyme inhibitor, as background treatment in the study. 

    The primary efficacy outcome was a modified version of the Scale for the Assessment and Rating of Ataxia (SARA), referred to as the functional SARA (fSARA). The fSARA consists of the gait, sitting, stance and speech disturbance domains of the original SARA with modifications to the scoring responses. On average, participants treated with Aqneursa for 12 weeks showed a better outcome in the fSARA score compared to when they were treated with placebo.

    The prescribing information contains a warning that Aqneursa may cause embryo-fetal harm if used during pregnancy. Females should inform their healthcare provider of a known or suspected pregnancy before taking Aqneursa.

    The most common side effects are abdominal pain, difficulty swallowing, upper respiratory tract infections and vomiting.

    Aqneursa should be taken orally up to three times per day, with or without food. The recommended dose varies depending on the individual’s body weight, as outlined in the prescribing information.

    The FDA granted Aqneursa Priority Review, Fast Track, Orphan Drug and Rare Pediatric Disease designations for this application.

    The FDA granted approval of Aqneursa to IntraBio Inc.

    Related Information

    ###

    Boilerplate

    The FDA, an agency within the U.S. Department of Health and Human Services, protects the public health by assuring the safety, effectiveness, and security of human and veterinary drugs, vaccines and other biological products for human use, and medical devices. The agency also is responsible for the safety and security of our nation’s food supply, cosmetics, dietary supplements, products that give off electronic radiation, and for regulating tobacco products.


    Inquiries

    Consumer:
    888-INFO-FDA

    MIL OSI USA News

  • MIL-OSI USA: FDA Roundup: September 24, 2024

    Source: US Department of Health and Human Services – 3

    For Immediate Release:

    Today, the U.S. Food and Drug Administration is providing an at-a-glance summary of news from around the agency: 

    • Today, the FDA held a ribbon-cutting ceremony to highlight the completion of the 64,000 square foot expansion and renovation of the National Forensic Chemistry Center (NFCC)  located in Cincinnati, Ohio.  The goal of this revitalization effort was to improve FDA’s mission readiness nationally and help attract and retain highly qualified employees. The NFCC is a specialty laboratory that serves as the FDA’s national forensic laboratory providing specialized laboratory services in analytical chemistry and molecular/ microbiology related to adulteration/contamination, counterfeiting, and product tampering of FDA regulated commodities including drugs, dietary supplements, foods, cosmetics, veterinary feeds, and medical devices.
    • On Monday, the FDA issued a safety advisory cautioning pet owners that samples of two Answers Pet Food products made by Lystn LLC tested positive for Salmonella, a third product tested positive for Listeria monocytogenes (L. mono), and a fourth product tested positive for Salmonella and L. mono. The FDA collected and tested unopened retail samples of products after receiving three consumer complaints of illness in dogs that ate the products. The affected products are sold frozen in 4-pound (half-gallon) cartons and consist of certain batches of Answers Pet Food Raw Beef Detailed Formula for Dogs, Answers Pet Food Raw Beef Straight Formula for Dogs, and Answers Pet Food Straight Chicken Formula for Dogs. Information to help consumers identify affected batches of product can be found in the Product Information section of the advisory. These products should not be fed to pets.
    • On Friday, the FDA approved isatuximab-irfc (Sarclisa) with bortezomib, lenalidomide, and dexamethasone for adults with newly diagnosed multiple myeloma who are not eligible for autologous stem cell transplant (ASCT).  The most common adverse reactions (≥20%) were upper respiratory tract infection, diarrhea, fatigue, peripheral sensory neuropathy, pneumonia, musculoskeletal pain, cataract, constipation, peripheral edema, rash, infusion-related reaction, insomnia, and COVID-19 infection. Full prescribing information for Sarclisa will be posted on Drugs@FDA.
    • On Friday, the FDA issued a safety advisory cautioning pet owners that FDA samples of five Darwin’s Natural Pet Products raw cat and dog food made by Arrow Reliance, Inc. tested positive for Salmonella and a sixth FDA sample tested positive for Salmonella and L. mono. Affected products are sold in frozen 2-pound packages and consist of certain lots of Darwin’s Natural Selections Antibiotic & Grain-Free Chicken Recipe for Cats and Darwin’s Natural Selections Antibiotic & Grain-Free Chicken Recipe for Dogs. These product lots should not be fed to pets. For specific product information and to learn about potential signs of illness, see the FDA Advisory.

    Related Information

    ###

    Boilerplate

    The FDA, an agency within the U.S. Department of Health and Human Services, protects the public health by assuring the safety, effectiveness, and security of human and veterinary drugs, vaccines and other biological products for human use, and medical devices. The agency also is responsible for the safety and security of our nation’s food supply, cosmetics, dietary supplements, radiation-emitting electronic products, and for regulating tobacco products.


    Inquiries

    Consumer:
    888-INFO-FDA

    MIL OSI USA News

  • MIL-OSI USA: FDA Roundup: September 20, 2024

    Source: US Department of Health and Human Services – 3

    For Immediate Release:

    Today, the U.S. Food and Drug Administration is providing an at-a-glance summary of news from around the agency: 

    • Today, the FDA and NIH announced “Advancing Smoking Cessation: FDA and NIH Priorities” – a joint public meeting focused on advancing innovation of smoking cessation products to help both adults and youth. The meeting will be held October 21, 2024, and will feature presentations and panel discussions on several smoking cessation-focused topics, as well as an opportunity for public comment on several topics related to cessation.
    • On Thursday, the FDA approved Zenrelia (ilunocitinib tablets), a new animal drug used to control pruritus (itching) associated with allergic dermatitis and to control atopic dermatitis (environmental allergies) in dogs at least 1 year of age.

      Zenrelia is safe and effective when used according to the label. However, the product labeling carries a boxed warning stating that dogs should not be vaccinated at least 28 days before and after treatment with Zenrelia, due to the risk of fatal vaccine-induced disease and inadequate immune response to vaccines.

    • On Thursday, the FDA approved Rybrevant (amivantamab-vmjw) with carboplatin and pemetrexed for adult patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) exon 19 deletions or exon 21 L858R substitution mutations whose disease has progressed on or after treatment with an EGFR tyrosine kinase inhibitor. Full prescribing information for Rybrevant will be posted on Drugs@FDA. 
    • On Wednesday, the FDA’s Center for Veterinary Medicine announced that it is supporting a collaborative agreement to the Reagan-Udall Foundation for the FDA to conduct a strengths, weaknesses, opportunities, and threats (SWOT) analysis. This SWOT analysis aims to research the challenges within, and unmet needs of, the animal health, animal food and veterinary industries, and explain the economic impact of these gaps.
    • On Wednesday, the FDA’s Center for Veterinary Medicine announced the establishment of four Animal and Veterinary Innovation Centers (AVICs) and recipients of funding for work to advance regulatory science and further development of innovative products and approaches to better support animal health and veterinary interventions. These AVICs further the goals outlined in the FDA’s Animal and Veterinary Innovation Agenda (AVIA), which describes the agency’s plans to spur innovation to better protect human and animal health. The three areas of concentration for the AVICs focus on:
      • Highly Pathogenic Avian Influenza (HPAI) and emerging zoonotic disease threats or One Health issues; 
      • Intentional genomic alternations (IGAs) in animals and the advancement of regulatory science in this field, with a focus on IGAs that support agricultural resilience, food security, animal health, or public health; and 
      • Unmet veterinary medical needs in both minor and major species that create a significant animal or public health burden.
    • On Wednesday, the FDA updated the outbreak advisory, Investigation of Illnesses: Diamond Shruumz-Brand Chocolate Bars, Cones, & Gummies to include additional cases.
    • On Tuesday, the FDA approved Kisqali (ribociclib) with an aromatase inhibitor for the adjuvant treatment of adults with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative stage II and III early breast cancer at high risk of recurrence. Additionally, the FDA also approved the Kisqali Femara Co-Pack (ribociclib and letrozole co-pack,) for the same indication. Full prescribing information for Kisqali and Kisqali Femara Co-Pack will be posted on Drugs@FDA. 
    • On Tuesday, the FDA approved Keytruda (pembrolizumab) with pemetrexed and platinum chemotherapy as first-line treatment of unresectable advanced or metastatic malignant pleural mesothelioma (MPM). Full prescribing information for Keytruda will be posted on Drugs@FDA.

    Related Information

    ###

    Boilerplate

    The FDA, an agency within the U.S. Department of Health and Human Services, protects the public health by assuring the safety, effectiveness, and security of human and veterinary drugs, vaccines and other biological products for human use, and medical devices. The agency also is responsible for the safety and security of our nation’s food supply, cosmetics, dietary supplements, radiation-emitting electronic products, and for regulating tobacco products.


    Inquiries

    Consumer:
    888-INFO-FDA

    MIL OSI USA News

  • MIL-OSI Global: Airdropping vaccines to eliminate canine rabies in Texas – two scientists explain the decades of research behind its success

    Source: The Conversation – USA – By Rodney E. Rohde, Regents’ Professor & Chair, Medical Laboratory Science, Texas State University

    Rabies is a fatal disease for both animals and people. CDC/Barbara Andrews

    Rabies is a deadly disease. Without vaccination, a rabies infection is nearly 100% fatal once someone develops symptoms. Texas has experienced two rabies epidemics in animals since 1988: one involving coyotes and dogs in south Texas, and the other involving gray foxes in west central Texas. Affecting 74 counties, these outbreaks led to thousands of people who could have been exposed, two human deaths and countless animal lives lost.

    In 1994, Gov. Ann Richards declared rabies a state health emergency. The Texas Department of State Health Services responded by launching the Oral Rabies Vaccination Program to control the spread of these wildlife rabies outbreaks.

    Since 1995, the program has distributed over 53 million doses of rabies vaccine over 758,100 square miles (nearly 2 million square kilometers) in Texas by hand or aircraft. Rabies cases in dogs and coyotes went from 141 to 0 by 2005, and rabies cases in foxes went from 101 to 0 by 2014. By 2004, one canine rabies variant was effectively eliminated from Texas, and another variant was substantially controlled.

    We are researchers who began studying wildlife rabies and oral vaccination in the 1980s. From providing a proof of concept in using oral vaccines in raccoons to being among the first to use new rabies vaccines in the 1990s, we were on the ground floor of efforts to contain this deadly virus.

    Decades of vaccine research led to one of the most successful public health projects in Texas. And we’re hopeful it could provide a road map for the use of mass wildlife vaccination to prevent future outbreaks.

    Developing the oral rabies vaccine

    The Texas Oral Rabies Vaccination Program benefited greatly from the work of multiple researchers over prior decades.

    The mid-20th century saw several major developments in rabies control. With the failure of efforts to poison or trap infected animals, virologist and veterinarian George Baer at the U.S. Centers for Disease Control and Prevention recognized the need for a different strategy to prevent and control wildlife rabies. His and his colleagues’ work in the 1960s led to the concept of oral rabies vaccination. While orally vaccinating wildlife would help combat infection at its source, it was previously thought to be logistically unfeasible given the large range of target animals.

    By the late 1970s, European researchers began the first field trials to orally vaccinate foxes against rabies. Small plastic containers were filled with vaccines and placed into baits, such as chicken heads. Over 50,000 of these vaccine-laden baits were distributed over four years in fox habitats in forests and fields.

    Early vaccine baits were coated with fishmeal crumbles and cod liver oil.
    Maki et al/Veterinary Research, CC BY-ND

    Researchers in Canada also began similar field trials in Ontario. During the 1980s, an average of 235 rabid foxes per year were reported in the area. Baits containing oral rabies vaccine were dropped annually from 1989 to 1995 and successfully eliminated the fox variant of rabies from the whole area.

    Recombinant oral rabies vaccine

    The first generation of these vaccines used live viruses modified in an attempt to not cause severe disease. Although effective and generally safe, the original rabies vaccines had to be kept in cool temperatures and had the rare risk of causing rabies in animals.

    In the early 1980s, scientists developed recombinant rabies vaccines, which use a separate virus to express the genes of the rabies virus. A collaboration between a nonprofit institute, the U.S. government, and the pharmaceutical industry led to the development of a recombinant viral vaccine that produced a rapid immune response against rabies without the possibility of causing rabies.

    In 1984, preliminary work in laboratory animals showed the promise of using an oral form of the recombinant vaccine to vaccinate animals. However, the concept of using genetically modified organisms was in its infancy among both scientists and the general public. While the vaccine was safe and effective in captive raccoons and foxes, major questions loomed over how it might affect other species once released into the environment.

    After years of work improving the vaccine’s design and testing its safety in several nonhuman species, the first European trial was held on a military base in Belgium. With data supporting it could safely and effectively control wildlife in Luxembourg and France, the vaccine was licensed to control fox rabies in 1995.

    In the U.S., similar studies of the oral recombinant rabies vaccine were conducted. The first trial began in 1990 at Parramore Island off the Virginia coast, and a year of intensive monitoring found no significant adverse effects on the environment or any wildlife species. A second yearlong study on the mainland near Williamsport, Pennsylvania, had similarly positive results.

    After the vaccine was successfully used to control raccoon rabies in tests in several other East Coast states, it was approved for use on raccoons in 1997.

    In 1998, the U.S. Department of Agriculture’s Animal and Plant Health Inspection Service and the U.S. Fish and Wildlife Service received funding to expand existing oral wildlife vaccination projects to states of strategic importance, to prevent the spread of specific rabies viruses, and to coordinate interstate projects.

    Results in Texas

    In Texas, the oral recombinant vaccine is now primarily distributed by hand and by approximately 75 separate helicopter flights annually.

    The Texas Department of State Health Services rabies laboratory worked alongside the CDC to create the Regional Rabies Virus Reference Typing Laboratory. One of us was recruited to both distribute the vaccine in the field and to develop molecular typing tools to discriminate between different types of rabies virus variants in the lab. These techniques allowed us to identify where different rabies virus variants were emerging at any given moment.

    The Texas Oral Rabies Vaccination Program continues to monitor and control rabies cases in the state.

    Our lab was also the first in the nation outside of the CDC to assist other U.S. states and countries in testing their specimens for rabies virus variants. These techniques helped researchers monitor where the rabies epizootic was ongoing or retreating due to wildlife vaccination and new forms of spread.

    With the constant threat of emerging and reemerging infectious diseases like COVID-19 and influenza, the prospect of mass vaccination of wild animals may be one way to address future pandemics. Though there is much work ahead of us, we have hope that we may one day have the option of using mass wildlife vaccination to reduce or eliminate infectious diseases like rabies.

    Rodney E. Rohde has received funding from the American Society of Clinical Pathologists, American Society for Clinical Laboratory Science, U.S. Department of Labor (OSHA), and other public and private entities/foundations. Rohde is affiliated with ASCP, ASCLS, ASM, and serves on several scientific advisory boards.

    Charles E. Rupprecht consults for global academic, governmental, industrial and NGO organizations. He receives funding from academic, governmental, industrial, and NGO sources.

    ref. Airdropping vaccines to eliminate canine rabies in Texas – two scientists explain the decades of research behind its success – https://theconversation.com/airdropping-vaccines-to-eliminate-canine-rabies-in-texas-two-scientists-explain-the-decades-of-research-behind-its-success-238508

    MIL OSI – Global Reports

  • MIL-OSI USA: NFL and FEMA Launch National Strategy to Build Resilience in Communities, Designate Venues as Mission Ready Locations During Disasters

    Source: US Federal Emergency Management Agency

    Headline: NFL and FEMA Launch National Strategy to Build Resilience in Communities, Designate Venues as Mission Ready Locations During Disasters

    NFL and FEMA Launch National Strategy to Build Resilience in Communities, Designate Venues as Mission Ready Locations During Disasters

    WASHINGTON — Stadiums and venues provide a central and accessible location to help communities respond to extreme weather crises, providing safe storage and shelter in times of need. With these events becoming more frequent, severe and expensive, FEMA Administrator Deanne Criswell and NFL Chief Security Officer Cathy Lanier today announced that FEMA and the NFL are launching a new strategy to build resilience in communities through a program that will designate NFL stadiums and fields as mission capable venues that can be used during response and recovery missions. Through Mission Ready Venues, a public-private partnership, NFL stadiums are recognized for their capabilities to better sustain public safety and be a source of support for the communities they serve. The designation identifies the ways the stadium or venue could be used for response and recovery activities during declared emergencies or disasters. 

    “During large-scale emergencies, like the COVID-19 pandemic, hurricanes, or tornados, we’ve seen how large music, sports and entertainment venues can serve as a safe space for communities,” said FEMA Administrator Deanne Criswell. “This new strategy we’re launching with the NFL is a groundbreaking opportunity to help our partners use these venues for emergency response and recovery needs, while keeping communities safe and making them more resilient. While we are starting with the NFL, all venues across sports organizations and leagues can become assets to their communities, and I encourage them to join in this collaborative effort as we grapple with the impacts of the climate crisis.”

    “Stadiums are valuable community assets that are often used in times of disasters,” said NFL Chief Security Officer Cathy Lanier. “This designation reflects the role that many stadiums play, not only on Sundays, but especially in times of need. We are proud to work with FEMA and first responders at the local and state level to ensure disaster response agencies have the information and tools they need to help a community recover when disaster strikes.”

    According to the NYU School of Professional Studies and the U.S. Conference of Mayors, stadiums and arenas can improve the public health and well-being of their communities—including pandemic response during COVID-19. The initial stadiums to receive designations include MetLife, home of the Jets and the Giants in East Rutherford, New Jersey, Lumen Field, home of the Seahawks in Seattle, Washington, Acrisure Stadium, home of the Steelers in Pittsburgh, Pennsylvania and Raymond James Stadium, home of the Buccaneers in Tampa, Florida. SoFi Stadium, home of the Rams and the Chargers in Los Angeles, California is under review. 

    Given the size, capabilities and locations of large sports venues, these existing community assets can serve the public in a variety of ways including emergency shelters, staging areas, commodity distribution sites, evacuation pick up points, disaster recovery centers, mass vaccination and testing, temporary hospitals and more. FEMA and the NFL recognized this unique opportunity for collaboration and are enlisting the support of venue owners, operators and the tenants of these facilities to work with government officials in the planning and preparation for emergency or disaster response and recovery efforts. To receive an official Mission Ready Venue designation, venues must undergo a comprehensive assessment to determine what capabilities the venue may be able to support in emergency and disaster response and recovery efforts. The designation highlights the following attributes of selected venues:

    • Provide Safety and Security: Stadiums are usually centrally located, close to major roadways and transportation hubs and critical services like hospitals. If used to respond to a disaster, the designation will save valuable time and resources and will further enhance coordination between the public and private sectors during disaster response and recovery.
    • Provide Accessibility: Stadiums are also compliant with Americans with Disabilities Act and can support persons with disabilities and others with access or functional needs. Additionally, 73% of NFL venues are accessible by mass transportation. This provides an avenue to promote equitable service to underserved populations to access potentially critical lifesaving/life-sustaining services after an event.  
    • Strengthen Community Resilience: Stadiums and arenas are a focal point of communities and help strengthen social networks by enhancing connections between residents with home team pride. These Mission Ready Venues can boost morale amidst disaster. By providing a more robust and resilient environment, these venues can enhance social networks amongst survivors while providing ample opportunities to establish connections with the venue’s main tenants.
    • Ensure Unity of Effort: Coordination of stadium resources and services can support survivors and responders and help stabilize an incident quickly. Since stadiums are fixed locations, resources and services can be deployed quickly. This promotes the community’s physical and economic recovery.

    Mission Ready Venue designations are for five-year increments with a yearly check-in to ensure continued readiness of the venue. Redesignation will be necessary every five years and designation does not supersede any agreements with state, local or private sector entities. 

    amy.ashbridge

    MIL OSI USA News

  • MIL-OSI USA: VIDEO RELEASE: Sen. Johnson’s Full Roundtable Discussion, American Health and Nutrition: A Second Opinion

    US Senate News:

    Source: United States Senator for Wisconsin Ron Johnson

    WASHINGTON – On Monday, U.S. Sen. Ron Johnson (R-Wis.) led a roundtable discussion titled, American Health and Nutrition: A Second Opinion. Sen. Johnson and a panel of experts provided a foundational and historical understanding of the changes that have occurred over the last century within agriculture, food processing, and healthcare industries which impact the current state of national health.  

     

    Watch the full four-hour discussion here. 

    PARTICIPANTS: 

    Dr. Casey Means

    Dr. Casey Means is a medical doctor, New York Times bestselling author, tech entrepreneur (Levels), aspiring regenerative gardener, and outdoor enthusiast. While training as a surgeon, she saw how broken and exploitative the healthcare system is and left to focus on how to keep people out of the operating room. 

    Dr. Jordan Peterson

    Dr. Jordan B. Peterson is a renowned psychologist, author, and online educator. His bestselling books, including “12 Rules for Life” and “Beyond Order,” have sold millions of copies worldwide. Dr. Peterson’s lectures and podcasts consistently attract large audiences, providing valuable insights into topics such as mythology, psychology, and personal development.

    Calley Means

    Calley Means is the co-founder of Truemed, a company that enables tax-free spending on food and exercise. He recently started an advocacy coalition with leading health and wellness companies called End Chronic Disease. Earlier in his career, he was a consultant for food and pharma companies and is now exposing practices they use to weaponize our institutions of trust. 

    Mikhaila Fuller

    Mikhaila Fuller is a podcaster, lifestyle and diet blogger, the Co-Founder and CEO of Peterson Academy, and the founder of Fuller Health and The Lion Diet. The Lion Diet is a therapeutic and plant free ketogenic diet that can be used to treat autoimmunity and psychiatric disorders. On “The Mikhaila Peterson Podcast,” she discusses health, cultural phenomena, politics, and other topics.

    Alex Clark

    Alex Clark is a food activist, advocate for healthier food systems, and host of the “Culture Apothecary” podcast. She is committed to educating consumers on the importance of organic farming and the dangers of harmful additives in food products. Clark’s mission is to inspire positive change in both personal health choices and industry standards, driving the movement toward cleaner, more responsible food production.

    Vani Hari (Food Babe)

    Vani Hari, known as the “Food Babe,” is a food activist, author, and speaker committed to improving food quality and safety. She has built a powerful platform through her blog, advocating for transparency in food labeling, and the removal of harmful chemicals from processed foods. Her activism has spurred significant changes in the food industry, encouraging consumers to make healthier, more informed choices while prompting companies to adopt cleaner practices. 

    Jillian Michaels

    Jillian Michaels is a globally recognized fitness expert, entrepreneur, and best-selling author. With her no-nonsense approach to health, she has inspired millions through her fitness programs, books, and digital platforms. Best known for her role on “The Biggest Loser,” Michaels promotes a balanced approach to fitness and nutrition, emphasizing long-term health and self-empowerment.

    Max Lugavere

    Max Lugavere is a leading health and wellness advocate, filmmaker, and New York Times bestselling author of “Genius Foods.” His work focuses on the link between diet, lifestyle, and brain health, and he has become a trusted voice in educating people about how nutrition impacts cognitive function.

    Dr. Chris Palmer

    Dr. Chris Palmer, MD is a Harvard-trained psychiatrist, researcher, and author of “Brain Energy,” where he explores the groundbreaking connection between metabolic health and mental illness. He is a leader in innovative approaches to treating psychiatric conditions, advocating for the use of diet and metabolic interventions to improve mental health outcomes. Dr. Palmer’s work is reshaping how the medical field views and treats mental health disorders. 

    Brigham Buhler

    Brigham Buhler is the founder and CEO of Ways2Well, a healthcare company that provides personalized preventative care through telemedicine. With a strong background in the pharmaceutical industry, Buhler has focused on making healthcare more accessible by harnessing the power of technology to deliver effective and tailored treatments. His vision for improving health outcomes has positioned him as a leader in modern, patient-centered healthcare solutions.

    Courtney Swan

    Courtney Swan is a nutritionist, real food activist, and founder of the popular platform “Realfoodology.” She advocates for transparency in the food industry, promoting the importance of whole foods and clean eating. Swan is passionate about educating the public on the benefits of a nutrient-dense diet, and she encourages sustainable, chemical-free farming practices to ensure better health for people and the planet.

    Jason Karp

    Jason Karp is the Founder and CEO of HumanCo – a mission-driven company that invests in and builds brands focused on healthier living and sustainability. In addition to HumanCo, Jason is the Co-Founder of Hu Kitchen, known for creating the #1 premium, organic chocolate in the U.S.. Prior to HumanCo, Jason spent over 21 years in the hedge fund industry where he was the Founder and CEO of an investment fund that managed over $4 billion. Jason graduated summa cum laude from the Wharton School of the University of Pennsylvania.

    Grace Price

    Grace Price is an 18-year-old citizen scientist and health activist. Grace gained recognition for her documentary Cancer: A Food-Borne Illness, which challenged the commonly held belief that cancer is a genetic disease. The main focus of her work is advocating for the health of her generation through exposing the corruption behind big food and pharmaceutical conglomerates. 

    Dr. Marty Makary

    Dr. Marty Makary MD, MPH is a surgeon and public policy researcher at Johns Hopkins University. He writes for The Washington Post and The Wall Street Journal and is the author of two New York Times bestselling books, “Unaccountable” and “The Price We Pay.” He has been an outspoken opponent of broad vaccine mandates and some COVID restrictions at schools. Dr. Makary holds degrees from Bucknell University, Thomas Jefferson University, and Harvard University. 

    MIL OSI USA News

  • MIL-OSI USA: Acrisure Stadium to Become a Mission Ready Venue

    Source: US Federal Emergency Management Agency

    Headline: Acrisure Stadium to Become a Mission Ready Venue

    Acrisure Stadium to Become a Mission Ready Venue

    Serving as a Vital Location During Disasters and Part of the NFL and FEMA’s National Strategy to Make Venues Mission Capable During Disasters

    PENNSYLVANIA — Stadiums and venues provide a central and accessible location to help communities respond to extreme weather crises, providing safe storage and shelter in times of need. With these events becoming more frequent, severe, and expensive, FEMA Administrator Deanne Criswell and NFL Chief Security Officer Cathy Lanier today announced that Acrisure Stadium in Pittsburgh, Pennsylvania, home of the Pittsburgh Steelers and University of Pittsburgh Panthers football, and a venue for touring concerts and events, will be among the first NFL venues to be designated as a Mission Ready Venue that can be used during response and recovery missions. Through Mission Ready Venues, a public-private partnership, Acrisure Stadium will increase its capabilities to better sustain public safety and be a source of support for the southwestern Pennsylvania community. The designation identifies the ways Acrisure Stadium could be used for response and recovery activities during declared emergencies or disasters.

    “We’re honored that Acrisure Stadium is among the first four NFL stadiums selected for Mission Ready Venue designation,” said James V. Sacco, Vice President of Stadium Operations & Management for Acrisure Stadium. Working collaboratively with the facility owner – the Sports and Exhibition Authority – this designation positions the stadium to partner seamlessly with local, state and federal government officials to serve the Pittsburgh community in a time of crisis or disaster. 

    During large-scale emergencies, like the COVID-19 pandemic, hurricanes, or tornadoes, we’ve seen how large music, sports and entertainment venues can serve as a safe space for communities,” said FEMA Administrator Deanne Criswell. “This new strategy we’re launching with the NFL is a groundbreaking opportunity to help our partners use these venues for emergency response and recovery needs, while keeping communities safe and making them more resilient. While we are starting with the NFL, all venues across sports organizations and leagues can become assets to their communities, and I encourage them to join in this collaborative effort as we grapple with the impacts of the climate crisis.”

    “Stadiums are valuable community assets that are often used in times of disasters,” said NFL Chief Security Officer Cathy Lanier. “This designation reflects the role that many stadiums play, not only on Sundays, but especially in times of need. We are proud to work with FEMA and first responders at the local and state level to ensure disaster response agencies have the information and tools they need to help a community recover when disaster strikes.” 

    According to the NYU School of Professional Studies and the U.S. Conference of Mayors, stadiums and arenas can improve the public health and well-being of their communities —including pandemic response during COVID-19. 

    “Identifying facilities in the community that can be used to support emergency management functions before a disaster or emergency occurs is critically important to ensuring an effective response and recovery,” said Pennsylvania Emergency Management Agency (PEMA) Director Randy Padfield. “The private sector has always been a committed partner and their willingness to participate in programs like this strengthens planning efforts at the local, state and federal level.”

    Given the size, capabilities, and locations of large sports venues, these existing community assets can serve the public in a variety of ways including emergency shelters, staging areas, commodity distribution sites, evacuation pick up points, disaster recovery centers, mass vaccination and testing, temporary hospitals and more. FEMA and the NFL recognized this unique opportunity for collaboration and are enlisting the support of venue owners, operators, and the tenants of these facilities to work with government officials in the planning and preparation for emergency or disaster response and recovery efforts. To receive an official Mission Ready Venue designation, venues must undergo a comprehensive assessment to determine what capabilities the venue may be able to support in emergency and disaster response and recovery efforts. The designation highlights the following attributes of selected venues: 

    • Provide Safety and Security: Stadiums are usually centrally located, close to major roadways and transportation hubs, and critical services like hospitals. If used to respond to a disaster, the designation will save valuable time and resources and will further enhance coordination between the public and private sectors during disaster response and recovery. 
    • Provide Accessibility: Stadiums are also compliant with Americans with Disabilities Act and can support persons with disabilities and others with access or functional needs. Additionally, 73% of NFL venues are accessible by mass transportation. This provides an avenue to promote equitable service to underserved populations to access potentially critical lifesaving/life sustaining services after an event. 
    • Strengthen Community Resilience: Stadiums and arenas are a focal point of communities and help strengthen social networks by enhancing connections between residents with home team pride. These Mission Ready Venues can boost morale amidst disaster. By providing a more robust and resilient environment, these venues can enhance social networks amongst survivors while providing ample opportunities to establish connections with the venue’s main tenants.
    • Ensure Unity of Effort: Coordination of stadium resources and services can support survivors and responders and help stabilize an incident quickly. Since stadiums are fixed locations, resources and services can be deployed quickly. This promotes the community’s physical and economic recovery.

    Mission Ready Venue designations are for five-year increments with a yearly check-in to ensure continued readiness of the venue. Redesignation will be necessary every five years and designation does not supersede any agreements with state, local or private sector entities.

    ###

    FEMA’s mission is helping people before, during, and after disasters. FEMA Region 3’s jurisdiction includes Delaware, the District of Columbia, Maryland, Pennsylvania, Virginia and West Virginia. Follow us on X at x.com/FEMAregion3 and on LinkedIn at linkedin.com/company/femaregion3

    erika.osullivan

    MIL OSI USA News

  • MIL-OSI Global: How better community engagement can improve emergency management in Canada

    Source: The Conversation – Canada – By Sayra Cristancho, Associate Professor, Department of Surgery and Faculty of Education Scientist, Centre for Education Research & Innovation, Western University

    Environmental, social and public health emergencies are becoming more frequent and severe around the world. The rapid pace at which emergencies are occurring, compounded by social crises like homelessness, addictions and mental health, are over-stressing our emergency management systems. However, as a society we cannot let this reality become an excuse.

    In response, the World Health Organization (WHO) has called for community engagement. And yet, despite a thriving legacy of volunteerism, Canada is lagging behind. Canada is the only G7 country without a national health security and emergency agency. And without such coordinating agency, communities are left to scramble when emergencies strike.

    When emergencies arise, the Canadian Armed Forces (CAF) are often called up to provide much needed support. However, the military is supposed to be called upon only when demand exceeds provincial capacity. Yet provinces have come to view the CAF as their first, rather than their last resort. Every time the CAF is called for assistance, it diverts time and resources away from attending to Canada’s national security tasks.

    If not the CAF, then what should be the source of this labour? There are four basic models Canada could follow. One of them pertains to mobilizing volunteer and skilled labour at the community level. The reality is that ordinary citizens always find their way to get involved, making emergency management a community concern. This is what the WHO refers to as a “whole-of-society approach.”

    Those in charge of devising the national emergency management strategy are confronted with two major uncertainties: the evolution of grass-roots initiatives to tackle community emergencies, and the lack of integration of those initiatives into emergency management systems.

    Community volunteers still feel that they work as “add-ons” rather than from within emergency management plans. The massive participation of citizens during forest fires and flood emergencies, and the increasing involvement of ordinary citizens in volunteer emergency response groups confirm that Canada enjoys a vibrant civil society. With its access to local networks, and its ability to mobilize others, community volunteers represent a unique and cost-effective resource.

    The Cobourg Community Centre Clinic

    Volunteers in communities across Canada are emotionally invested to help and engage during emergencies, particularly when they perceive poor coordination or lapses in authority by official response organizations.

    This was the case, as colleagues and I recently documented, of the Cobourg Community Centre (CCC) COVID-19 vaccination response in Ontario.

    This community initiative involved 600 volunteers who stepped up to help their community build and run a vaccination clinic when the community sensed that vaccination plans were not moving quickly enough. The Cobourg Rotary Club in partnership with the Northumberland Hills Hospital devised this initiative which involved retrofitting the community centre to serve as a clinic, organizing, and managing volunteer tasks, and assisting health-care providers in distributing vaccines.

    We interviewed volunteers, health-care providers, Rotary club members, public health unit staff, hospital staff, local businesses and city employees to capture the stories behind the clinic. These stories became the catalyst for positioning the CCC as a model of community engagement for crisis response.

    Several lessons were identified but likely the most insightful one for formal emergency agencies and government was the realization that emergency response is not always a complex and difficult task. In the case of the CCC, it was not difficult to drive seniors to the vaccination clinic. It was not difficult for volunteers to assist with documentation at the mobile clinics. It was not difficult for retired teachers to use stuffed toys so children wouldn’t be scared by the vaccine. And it was not difficult for local businesses to donate materials and labour so that the clinic was built according to protocol.

    Therefore, instead of making emergency response seem unduly complex for volunteers, emergency agencies ought to welcome their involvement. In fact, it might even be wise for emergency agencies to learn about the way community volunteers respond – since it seems they can be effective – to welcome their input, and thus enhance a community’s emergency response capacity.

    Three strategies communities can implement to get started

    If you and others would like to help prepare your community to become an effective partner to official emergency responders, here are some strategies to help organize your efforts:

    1. Foster ongoing relationships with community partners, not just during crisis.

    Remember that everyone brings expertise to the table and that partnerships may involve groups you don’t always think of. Therefore, welcome community partners as part of task forces. It helps the community see a different side of government organizations despite their reputation for being slow to pivot, or too bureaucratic.

    2. Maintain a repository of community members’ skills, don’t leave it to chance.

    During crisis, this repository or database will facilitate decision-making regarding distribution of tasks among volunteers and discover unique skills that otherwise would go unnoticed in a large community.

    3. Communicate through diverse channels, even if it feels redundant.

    Emergencies are emotionally draining for everyone. Frequent feedback and debriefing help strengthening engagement and morale. Therefore, use multiple and existing channels, such as huddles, newsletters, appreciation events, etc., and encourage community leaders to spread information to the larger community.

    Communities have shown that they play a vital role to large and small emergency responses: from COVID-19 tracing and vaccination, to organizing post-flood volunteer recovery efforts via digital platforms. However, community initiatives are often not recognized by emergency response organizations, and as a result community volunteers are often under-utilized.

    This tension over how to engage community volunteers to effectively respond to crisis and work with formal emergency response teams requires we all change how we think.

    Contemporary emergency management demands all hands-on deck. As the Cobourg Community Centre clinic initiative demonstrated, instead of warding off community volunteers, the focus should be on ensuring they are ready to respond and educated on the scope of their involvement.

    Throughout her academic career, Sayra Cristancho has received tri-council research funding from the Canadian government as we all research funding from the Royal College of Physicians and Surgeons of Canada and internal research funding from Western University.

    ref. How better community engagement can improve emergency management in Canada – https://theconversation.com/how-better-community-engagement-can-improve-emergency-management-in-canada-239042

    MIL OSI – Global Reports

  • MIL-OSI USA: Lumen Field to Become a Mission Ready Venue

    Source: US Federal Emergency Management Agency

    Headline: Lumen Field to Become a Mission Ready Venue

    Lumen Field to Become a Mission Ready Venue

    BOTHELL, Wash – Stadiums and venues provide a central and accessible location to help communities respond to extreme weather crises, providing safe storage and shelter in times of need. With these events becoming more frequent, severe, and expensive, FEMA Administrator Deanne Criswell and NFL Chief Security Officer Cathy Lanier today announced that Lumen Field in Seattle, Washington, home of the Seahawks, will be among the first NFL venues to be designated as a Mission Ready Venue that can be used during response and recovery missions. Through Mission Ready Venues, a public-private partnership, Lumen Field will increase its capabilities to better sustain public safety and be a source of support for the community they serve. The designation identifies the ways Lumen Field could be used for response and recovery activities during declared emergencies or disasters.

    “The Seahawks and Lumen Field are proud to be one of the first NFL stadiums to be designated a Mission Ready Venue,” said Zach Hensley, Seattle Seahawks Vice President of Operations and General Manager of Lumen Field. “A commitment to community is fundamental to our organization, and the unique attributes that allow us to host more than two million guests each year can be an invaluable resource to the larger Pacific Northwest region in times of need.”

    “During large-scale emergencies, like the COVID-19 pandemic, hurricanes, or tornados, we’ve seen how large music, sports and entertainment venues can serve as a safe space for communities,” said FEMA Administrator Deanne Criswell. “This new strategy we’re launching with the NFL is a groundbreaking opportunity to help our partners use these venues for emergency response and recovery needs, while keeping communities safe and making them more resilient. While we are starting with the NFL, all venues across sports organizations and leagues can become assets to their communities, and I encourage them to join in this collaborative effort as we grapple with the impacts of the climate crisis.”

    “I’m pleased to have Lumen Field designated as a Mission Ready Venue,” said FEMA Region 10 Administrator Willie G. Nunn. “In a time of crisis, it’s important that we all work together and look at all options to support disaster survivors. Lumen Field is well-known in our community as a place to congregate for Seahawks games and other community events. When a large disaster strikes, it’s great to know that Lumen Field can play a pivotal role in helping our community.” 

    “Stadiums are valuable community assets that are often used in times of disasters,” said NFL Chief Security Officer Cathy Lanier. “This designation reflects the role that many stadiums play, not only on Sundays, but especially in times of need. We are proud to work with FEMA and first responders at the local and state level to ensure disaster response agencies have the information and tools they need to help a community recover when disaster strikes.” 

    According to the NYU School of Professional Studies and the U.S. Conference of Mayors, stadiums and arenas can improve the public health and well-being of their communities —including pandemic response during COVID-19. 

    “Seattle is proud that Lumen Field is designated as a disaster response and recovery venue,” said Curry Mayer, Director, Seattle Office of Emergency Management. “Lumen Field was successfully used as a mass vaccination site during the COVID pandemic. Lumen has all the amenities needed to serve the public and is easily accessible for Seattle’s communities.”

    Given the size, capabilities, and locations of large sports venues, these existing community assets can serve the public in a variety of ways including emergency shelters, staging areas, commodity distribution sites, evacuation pick up points, disaster recovery centers, mass vaccination and testing, temporary hospitals and more. FEMA and the NFL recognized this unique opportunity for collaboration and are enlisting the support of venue owners, operators, and the tenants of these facilities to work with government officials in the planning and preparation for emergency or disaster response and recovery efforts.  To receive an official Mission Ready Venue designation, venues must undergo a comprehensive assessment to determine what capabilities the venue may be able to support in emergency and disaster response and recovery efforts. The designation highlights the following attributes of selected venues: 

    • Provide Safety and Security: Stadiums are usually centrally located, close to major roadways and transportation hubs, and critical services like hospitals. If used to respond to a disaster, the designation will save valuable time and resources and will further enhance coordination between the public and private sectors during disaster response and recovery. 
    • Provide Accessibility: Stadiums are also compliant with Americans with Disabilities Act and can support persons with disabilities and others with access or functional needs. Additionally, 73% of NFL venues are accessible by mass transportation. This provides an avenue to promote equitable service to underserved populations to access potentially critical lifesaving/life sustaining services after an event. 
    • Strengthen Community Resilience: Stadiums and arenas are a focal point of communities and help strengthen social networks by enhancing connections between residents with home team pride. These Mission Ready Venues can boost morale amidst disaster. By providing a more robust and resilient environment, these venues can enhance social networks amongst survivors while providing ample opportunities to establish connections with the venue’s main tenants.
    • Ensure Unity of Effort: Coordination of stadium resources and services can support survivors and responders and help stabilize an incident quickly. Since stadiums are fixed locations, resources and services can be deployed quickly. This promotes the community’s physical and economic recovery.

    Mission Ready Venue designations are for five-year increments with a yearly check-in to ensure continued readiness of the venue. Redesignation will be necessary every five years and designation does not supersede any agreements with state, local or private sector entities. 

    ###

    Follow FEMA Region 10 on X and LinkedIn for the latest updates and visit FEMA.gov for more information.

    FEMA’s mission is helping people before, during, and after disasters.

    natalie.shaver

    MIL OSI USA News

  • MIL-Evening Report: Why are we seeing more pandemics? Our impact on the planet has a lot to do with it

    Source: The Conversation (Au and NZ) – By Olga Anikeeva, Research Fellow, School of Public Health, University of Adelaide

    ImageFlow/Shutterstock

    Pandemics – the global spread of infectious diseases – seem to be making a comeback. In the Middle Ages we had the Black Death (plague), and after the first world war we had the Spanish flu. Tens of millions of people died from these diseases.

    Then science began to get the upper hand, with vaccination eradicating smallpox, and polio nearly so. Antibiotics became available to treat bacterial infections, and more recently antivirals as well.

    But in recent years and decades pandemics seem to be returning. In the 1980s we had HIV/AIDS, then several flu pandemics, SARS, and now COVID (no, COVID isn’t over).

    So why is this happening, and is there anything we can do to avert future pandemics?

    Unbalanced ecosystems

    Healthy, stable ecosystems provide services that keep us healthy, such as supplying food and clean water, producing oxygen, and making green spaces available for our recreation and wellbeing.

    Another key service ecosystems provide is disease regulation. When nature is in balance – with predators controlling herbivore populations, and herbivores controlling plant growth – it’s more difficult for pathogens to emerge in a way that causes pandemics.

    But when human activities disrupt and unbalance ecosystems – such as by way of climate change and biodiversity loss – things go wrong.

    For example, climate change affects the number and distribution of plants and animals. Mosquitoes that carry diseases can move from the tropics into what used to be temperate climates as the planet warms, and may infect more people in the months that are normally disease free.

    We’ve studied the relationship between weather and dengue fever transmission in China, and our findings support the same conclusion reached by many other studies: climate change is likely to put more people at risk of dengue.

    COVID was not the first pandemic, and is unlikely to be the last.
    Jaromir Chalabala/Shutterstock

    Biodiversity loss can have similar effects by disrupting food chains. When ranchers cleared forests in South America for their cattle to graze in the first half of the 20th century, tiny forest-dwelling, blood-feeding vampire bats suddenly had a smörgåsbord of large sedentary animals to feed on.

    While vampire bats had previously been kept in check by the limited availability of food and the presence of predators in the balanced forest ecosystem, numbers of this species exploded in South America.

    These bats carry the rabies virus, which causes lethal brain infections in people who are bitten. Although the number of deaths from bat-borne rabies has now fallen dramatically due to vaccination programs in South America, rabies caused by bites from other animals still poses a global threat.

    As urban and agricultural development impinges on natural ecosystems, there are increasing opportunities for humans and domestic animals to become infected with pathogens that would normally only be seen in wildlife – particularly when people hunt and eat animals from the wild.

    The HIV virus, for example, first entered human populations from apes that were slaughtered for food in Africa, and then spread globally through travel and trade.

    Meanwhile, bats are thought to be the original reservoir for the virus that caused the COVID pandemic, which has killed more than 7 million people to date.

    Climate change can affect the distribution of animals which carry disease, such as mosquitoes.
    Kwangmoozaa/Shutterstock

    Ultimately, until we effectively address the unsustainable impact we are having on our planet, pandemics will continue to occur.

    Targeting the ultimate causes

    Factors such as climate change, biodiversity loss and other global challenges are the ultimate (high level) cause of pandemics. Meanwhile, increased contact between humans, domestic animals and wildlife is the proximate (immediate) cause.

    In the case of HIV, while direct contact with the infected blood of apes was the proximate cause, the apes were only being slaughtered because large numbers of very poor people were hungry – an ultimate cause.

    The distinction between ultimate causes and proximate causes is important, because we often deal only with proximate causes. For example, people may smoke because of stress or social pressure (ultimate causes of getting lung cancer), but it’s the toxins in the smoke that cause cancer (proximate cause).

    Generally, health services are only concerned with stopping people from smoking – and with treating the illness that results – not with removing the drivers that lead them to smoke in the first place.

    Similarly, we address pandemics with lockdowns, mask wearing, social distancing and vaccinations – all measures which seek to stop the spread of the virus. But we pay less attention to addressing the ultimate causes of pandemics – until perhaps very recently.

    Often we treat the proximate causes of illness, but not the ultimate causes.
    Basil MK/Pexels

    A planetary health approach

    There’s a growing awareness of the importance of adopting a “planetary health” approach to improve human health. This concept is based on the understanding that human health and human civilisation depend on flourishing natural systems, and the wise stewardship of those natural systems.

    With this approach, ultimate drivers like climate change and biodiversity loss would be prioritised in preventing future pandemics, at the same time as working with experts from many different disciplines to deal with the proximate causes, thereby reducing the risk overall.

    The planetary health approach has the benefit of improving both the health of the environment and human health concurrently. We are heartened by the increased uptake of teaching planetary health concepts across the environmental sciences, humanities and health sciences in many universities.

    As climate change, biodiversity loss, population displacements, travel and trade continue to increase the risk of disease outbreaks, it’s vital that the planetary stewards of the future have a better understanding of how to tackle the ultimate causes that drive pandemics.

    This article is the first in a series on the next pandemic.

    Olga Anikeeva receives funding from Green Adelaide.

    Jessica Stanhope receives funding from the Ecological Health Network and Green Adelaide. She is affiliated with the Environmental Physiotherapy Association.

    Peng Bi receives funding from the Australian Research Council, National Health and Medical Research Council, National Climate Change Adaptation Research Facility, AusAID,

    Philip Weinstein receives funding from competitive external granting bodies. He is affiliated with Nature Foundation, Australian Entomological Society, and the South Australian Museum.

    ref. Why are we seeing more pandemics? Our impact on the planet has a lot to do with it – https://theconversation.com/why-are-we-seeing-more-pandemics-our-impact-on-the-planet-has-a-lot-to-do-with-it-226827

    MIL OSI AnalysisEveningReport.nz

  • MIL-OSI NGOs: Concrete action needed in fight against antimicrobial resistance

    Source: Médecins Sans Frontières –

    • Governments must take bold action to make meaningful progress against drug resistance worldwide.
    • Drawing on our years of experience tackling drug resistance, we urge governments to build on their commitments at the second-ever United Nations High Level Meeting on antimicrobial resistance.

    Geneva/New York – Ahead of the second-ever United Nations (UN) High Level Meeting on antimicrobial resistanceAMR — when microbes like bacteria, viruses, and fungi evolve and survive despite the antimicrobial medicines, such as antibiotics, used against them — can make medical care less effective and much more difficult, prolonged, and costly for patients and treatment providers. (AMR) tomorrow, where world leaders will come together to agree on commitments to advance the global response to AMR, Médecins Sans Frontières (MSF) calls on governments to take swift, bold action to translate this political declaration into meaningful progress against drug resistance.

    Headway against AMR since the first declaration nearly a decade ago has been inadequate and inequitable, with low- and middle-income countries – and humanitarian contexts, in particular – least equipped to respond despite bearing the highest burdens of drug-resistant infection. Drawing on years of experience tackling drug resistance around the world, MSF urges governments to build on the commitments made and take an ambitious set of follow-on steps to empower those most affected by AMR to prevent, detect, and respond to it.

    AMR is a leading cause of death worldwide, and contributed to to 4.95 million deaths in 2019 alone, with recent estimates showing the threat is still growing at alarming rates, possibly contributing to 8.2 million deaths annually by 2050.https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)01867-1/fulltext

    “We are seeing staggering rates of drug-resistant infections in many of the low-resource and humanitarian settings where we work, in large part because healthcare workers don’t have what they need to prevent, detect, and respond to AMR,” says Dr Christos Christou, International President of MSF. “The UN Political Declaration on antimicrobial resistance is a welcome step towards strengthening the global AMR response and expresses important aspirations for global equity and solidarity.” 

    “Considering the magnitude of the challenge of AMR though, and how few of the hardest-hit countries have been able to fund and implement national action plans, the declaration text should have been much more concrete and ambitious,” he says. “The declaration must now go beyond words on paper: governments must not only enact and be accountable to the commitments they’ve made, but they must also build on and refine them to ensure low-resource and humanitarian settings are no longer left behind.”

    People in low- and middle-income countries experience the highest rates of AMR and infectious diseases globally, but are the least likely to have access to healthcare, including the medicines, vaccines, and diagnostics they need. In humanitarian settings, other factors compound the AMR crisis. Conflicts or natural disasters, for example, can result in traumatic injuries that can easily become infected and force people to take refuge in overcrowded settings where resistant bacteria can spread easily.

    In the political declaration, governments acknowledged the importance of addressing AMR in humanitarian settings like those in which MSF works, as well as several issues that MSF has highlighted as key priorities in responding to AMR. However, the commitments made to address these issues should have been bolder and more precisely calibrated to address global inequities. MSF recommends that governments build on and refine these commitments in the following ways:

    • The declaration’s commitment to include affected communities and humanitarian organisations in the governance of platforms and mechanisms to address AMR must now be put into practice. Only by ensuring the inclusive participation of these groups in global AMR initiatives can an effective roadmap for reaching the most underserved settings take shape. For example, if established, the proposed Independent Panel on Evidence for Action Against AMR must adhere to principles of impartiality, transparency, and accountability to all countries, and prioritise research in and for communities most affected by AMR. This is important, because communities in conflict-affected, fragile and humanitarian settings are more vulnerable to AMR, but evidence needed to inform the response in these settings is acutely lacking.
    • The declaration recognizes the need for strengthening laboratory capacity and commits to “improve access to diagnosis and care,” but this broad commitment must be made more specific and precise in follow-on agreements and accountability frameworks to ensure expanded and equitable availability of quality-assured microbiology laboratories. Access to microbiology laboratories is a critical foundation for preventing, detecting and controlling AMR more effectively, but many places with high rates of AMR do not have quality laboratories. 
    • The commitment to increased international financing and technical assistance to enable low- and middle-income countries to implement national action plans to address AMR must result in stronger and more ambitious funding, as the currently proposed US$100 million to see 60 per cent of countries achieve funded plans to tackle AMR by 2030 is not sufficient to address a health issue of this magnitude.
    • The commitment to ensure timely and equitable access to affordable medical tools, including antimicrobials and diagnostic tests, must translate into concrete action. The significant global gaps in access to medical tools must be tracked and quantified to guide efforts to achieve more equitable access, and resources allocated accordingly for both access strategies and antimicrobial stewardship programs. Furthermore, when governments provide funding for research and development for new antimicrobials, they should prioritise public and nonprofit initiatives, as these facilitate access, stewardship, and collaborative approaches to research. Funders must also attach upfront conditions ensuring equitable global access to any resulting medical tools into agreements when providing the “push” and “pull” funding called for in the declaration.

    “To effectively combat AMR globally, governments must address the significant discrepancies in the amount of evidence for action available in high-income and low-resource settings,” said Dušan Jasovský, Antimicrobial Resistance Pharmacist with the MSF Access Campaign. “This means that the Independent Panel on Evidence for Action Against AMR proposed in the declaration must prioritise research in communities most affected by AMR, which are often in humanitarian or low-resource settings where there is currently the least evidence to guide action.”

    “This panel is in a great position to inform a response to drug resistance in the hardest-hit areas based on interventions that work, but to do so it must operate with transparency, accountability, and impartiality, backed by ambitious financial means of implementation, and in close collaboration with affected communities,” says Jasovský.

    MSF is a leading actor in preventing, detecting, and responding to AMR in humanitarian settings, with infection prevention and control, and stewardship initiatives across multiple contexts and 50 sites with planned or existing access to diagnostic microbiology in 20 countries worldwide. MSF has developed an interdisciplinary approach to addressing AMR which includes targeted training and support for infection prevention and control, and antimicrobial stewardship, and in some cases also efforts to provide access to microbiology lab-based diagnosis.

    MIL OSI NGO

  • MIL-Evening Report: Politics with Michelle Grattan: Richard Holden says no interest rate fall likely for 12 months

    Source: The Conversation (Au and NZ) – By Michelle Grattan, Professorial Fellow, University of Canberra

    For many Australians, the COVID-19 pandemic has become a fading memory as the world has moved away from lockdowns and masks. However, its lasting impacts, including persistent inflation, remain.

    Academic economists Steven Hamilton and Richard Holden, in their just-published book, Australia’s Pandemic Exceptionalism, examine how Australia fared in handling the COVID crisis in its economic and health policies.

    We’re joined on the podcast by Holden to talk about the book and also Australia’s economic outlook, during what has been a big week for economic news.

    On COVID, Hamilton and Holden found a mixed picture: Australia scored highly in its economic response but fell down on its vaccine procurement and provision of RATs.

    I think Treasury gave excellent advice to the Treasurer [Josh Frydenberg]  and he not only […] took that advice but was able to sell it to a sometimes sceptical cabinet. […] So I think it was good advice and strong leadership on the economic front. On the health front, I think the advice was really quite poor at times. I mean we make quite a point of Scott Morrison’s use of the phrase when it comes to vaccines “It’s not a race” when clearly it was a race. It was a race against the virus. It was a race to get vaccinated. It was a race to be able to reopen our economy.

    On the RBA and inflation, Holden agrees with this week’s decision to hold rates but believes they should have risen earlier at least once more:

    I have argued […] that late last year or early this year, the Reserve Bank should have raised rates at least one more time to get us closer to what happened in peer jurisdictions overseas, to try and beat inflation faster. The Reserve Bank has taken a different approach. They want to have interest rates peak, maybe a full percentage point lower than in places like the US, and they’re willing to tolerate inflation for longer.

    At least they’re not caving into political pressure from people like Jim Chalmers and Wayne Swan to precipitously cut interest rates and I give the governor, Michele Bullock, great credit for standing firm on that, including in her press conference remarks [on Tuesday].

    On when interest rates will start moving down, Holden gives a grim assessment:

    My view is the most likely case is very late in 2025, somewhere about 12 months from today. Again, it’s going to depend on the inflation numbers and I’d like nothing more [than] for us to be well inside the target band and for interest rates to be able to be moderated.

    I think it’s a real shame that we took a different strategy in Australia to what peer jurisdictions overseas did, which was raise rates more aggressively, take our medicine, have tamed inflation and now be cutting rates. That’s the story in the US and several other jurisdictions.

    Holden warns against RBA Governor Michele Bullock making predictions of future rate moves:

    Governor Bullock, I think, is at risk of repeating, albeit a milder version of, the mistake that Philip Lowe made in providing forward guidance. Now it’s not as dramatic as saying interest rates are not going to rise until 2024, which was sort of three years of forward guidance or thereabouts. Governor Bullock has fallen into, I think, a little bit of a trap by saying over six weeks ago that she and her colleagues on the board didn’t think that interest rates would be cut this calendar year.

    I don’t really understand what the virtue of her doing that was. I think that was probably, in hindsight, something that she may regret. [Although] I don’t think it will do any real damage because I think it’s a prediction that’s incredibly likely to come true.  

    On the government potentially making changes to negative gearing, Holden outlines why it could be a good idea:

    Getting rid of negative gearing would put potential owner-occupiers on a level playing field with investors at an auction. I think it’ll be very good news for people trying to move from the rental market into being owner-occupiers; I think it’ll be good news for the classic Australian dream. To be fair about it, the existence of negative gearing is something that puts downward pressure on rents. So negative gearing, in a funny way, is good for renters who are always going to rent but bad for renters who want to buy. So there are pros and cons.

    It was a good idea eight or nine years ago. I think it’s still a good idea today and I think it’s interesting that the government seems to be at least floating the test balloon.

    Michelle Grattan does not work for, consult, own shares in or receive funding from any company or organisation that would benefit from this article, and has disclosed no relevant affiliations beyond their academic appointment.

    ref. Politics with Michelle Grattan: Richard Holden says no interest rate fall likely for 12 months – https://theconversation.com/politics-with-michelle-grattan-richard-holden-says-no-interest-rate-fall-likely-for-12-months-239820

    MIL OSI AnalysisEveningReport.nz

  • MIL-OSI Submissions: UN Political Declaration on antimicrobial resistance essential step, but concrete action from governments now critical

    Source: Médecins Sans Frontières

    AMR remains a leading cause of death worldwide nearly a decade after UN member states agreed to make it a priority.

    Geneva/New York, 25 September 2024 – Ahead of the second-ever United Nations (UN) High Level Meeting on antimicrobial resistance* (AMR) tomorrow, where world leaders will come together to agree on commitments to advance the global response to AMR, Médecins Sans Frontières/Doctors Without Borders (MSF) called on governments to take swift, bold action to translate this political declaration into meaningful progress against drug resistance. 

    Headway against AMR since the first declaration nearly a decade ago has been inadequate and inequitable, with low- and middle-income countries – and humanitarian contexts, in particular – least equipped to respond despite bearing the highest burdens of drug-resistant infection. 

    Drawing on years of experience tackling drug resistance around the world, MSF urged governments to build on the commitments made and take an ambitious set of follow-on steps to empower those most affected by AMR to prevent, detect, and respond to it. AMR is a leading cause of death worldwide, and contributed to 4.95 million deaths in 2019 alone, with recent estimates showing the threat is still growing at alarming rates, possibly contributing to 8.2 million deaths annually by 2050.

    “We are seeing staggering rates of drug-resistant infections in many of the low-resource and humanitarian settings where we work, in large part because healthcare workers don’t have what they need to prevent, detect, and respond to AMR,” said Dr Christos Christou, International President of MSF. 

    “The UN Political Declaration on antimicrobial resistance is a welcome step towards strengthening the global AMR response and expresses important aspirations for global equity and solidarity. Considering the magnitude of the challenge of AMR though, and how few of the hardest-hit countries have been able to fund and implement national action plans, the declaration text should have been much more concrete and ambitious. 
    “The declaration must now go beyond words on paper: governments must not only enact and be accountable to the commitments they’ve made, but they must also build on and refine them to ensure low-resource and humanitarian settings are no longer left behind.”

    People in low- and middle-income countries experience the highest rates of AMR and infectious diseases globally, but are the least likely to have access to healthcare, including the medicines, vaccines, and diagnostics they need. In humanitarian settings, other factors compound the AMR crisis. Conflicts or natural disasters, for example, can result in traumatic injuries that can easily become infected and force people to take refuge in overcrowded settings where resistant bacteria can spread easily.

    In the political declaration, governments acknowledged the importance of addressing AMR in humanitarian settings like those in which MSF works, as well as several issues that MSF has highlighted as key priorities in responding to AMR. However, the commitments made to address these issues should have been bolder and more precisely calibrated to address global inequities. MSF recommends that governments build on and refine these commitments in the following ways:

    The declaration’s commitment to include affected communities and humanitarian organisations in the governance of platforms and mechanisms to address AMR must now be put into practice. Only by ensuring the inclusive participation of these groups in global AMR initiatives can an effective roadmap for reaching the most underserved settings take shape. 

    For example, if established, the proposed Independent Panel on Evidence for Action Against AMR must adhere to principles of impartiality, transparency, and accountability to all countries, and prioritise research in and for communities most affected by AMR. 
    This is important, because communities in conflict-affected, fragile and humanitarian settings are more vulnerable to AMR, but evidence needed to inform the response in these settings is acutely lacking.
    The declaration recognizes the need for strengthening laboratory capacity and commits to “improve access to diagnosis and care,” but this broad commitment must be made more specific and precise in follow-on agreements and accountability frameworks to ensure expanded and equitable availability of quality-assured microbiology laboratories. Access to microbiology laboratories is a critical foundation for preventing, detecting and controlling AMR more effectively, but many places with high rates of AMR do not have quality laboratories.
    The commitment to increased international financing and technical assistance to enable low- and middle-income countries to implement national action plans to address AMR must result in stronger and more ambitious funding, as the currently proposed US$100 million to see 60 per cent of countries achieve funded plans to tackle AMR by 2030 is not sufficient to address a health issue of this magnitude.
    The commitment to ensure timely and equitable access to affordable medical tools, including antimicrobials and diagnostic tests, must translate into concrete action. The significant global gaps in access to medical tools must be tracked and quantified to guide efforts to achieve more equitable access, and resources allocated accordingly for both access strategies and antimicrobial stewardship programs. 
    Furthermore, when governments provide funding for research and development for new antimicrobials, they should prioritise public and nonprofit initiatives, as these facilitate access, stewardship, and collaborative approaches to research. Funders must also attach upfront conditions ensuring equitable global access to any resulting medical tools into agreements when providing the “push” and “pull” funding called for in the declaration.

    “To effectively combat AMR globally, governments must address the significant discrepancies in the amount of evidence for action available in high-income and low-resource settings,” said Dušan Jasovský, Antimicrobial Resistance Pharmacist with the MSF Access Campaign. 

    “This means that the Independent Panel on Evidence for Action Against AMR proposed in the declaration must prioritise research in communities most affected by AMR, which are often in humanitarian or low-resource settings where there is currently the least evidence to guide action. This panel is in a great position to inform a response to drug resistance in the hardest-hit areas based on interventions that work, but to do so it must operate with transparency, accountability, and impartiality, backed by ambitious financial means of implementation, and in close collaboration with affected communities.”

    *AMR — when microbes like bacteria, viruses, and fungi evolve and survive despite the antimicrobial medicines, such as antibiotics, used against them — can make medical care less effective and much more difficult, prolonged, and costly for patients and treatment providers.

    MSF is a leading actor in preventing, detecting, and responding to AMR in humanitarian settings, with infection prevention and control, and stewardship initiatives across multiple contexts and 50 sites with planned or existing access to diagnostic microbiology in 20 countries worldwide. MSF has developed an interdisciplinary approach to addressing AMR which includes targeted training and support for infection prevention and control, and antimicrobial stewardship, and in some cases also efforts to provide access to microbiology lab-based diagnosis.

    MSF Australia was established in 1995 and is one of 24 international MSF sections committed to delivering medical humanitarian assistance to people in crisis. In 2022, more than 120 project staff from Australia and New Zealand worked with MSF on assignment overseas. MSF delivers medical care based on need alone and operates independently of government, religion or economic influence and irrespective of race, religion or gender. For more information visit msf.org.au

    MIL OSI – Submitted News

  • MIL-OSI United Kingdom: Ready for uni life? Use condoms to keep STIs away

    Source: United Kingdom – Executive Government & Departments

    UKHSA is advising students to use condoms when having sex with new or casual partners

    Sexually transmitted infections (STIs) remain high among young people. The most recent data from UKHSA shows that in 2023, among people aged 15 to 24, there were:

    • 104,107 cases of chlamydia
    • 4,617 cases of genital warts
    • 29,880 cases of gonorrhoea

    These infections spread easily, and those aged 15 to 24 are especially at risk as they are more likely to have frequent partner changes.

    While many STIs can be treated, untreated infections can lead to serious health issues. Chlamydia and gonorrhoea may cause infertility and pelvic inflammatory disease, while syphilis can result in severe, irreversible problems affecting the brain, heart, or nerves.

    Katy Sinka, Head of Sexually Transmitted Infections at UKHSA, said:

    If you’re having sex with someone new, or someone more casually, don’t forget to use a condom.

    With higher STI rates in young people, having sex without a condom can increase your chances of an infection like chlamydia or gonorrhoea. Getting tested regularly will also help detect any infections quickly and protect your own and your partners health.

    Some people will have symptoms of an infection (such as a discharge, pain while urinating or an unusual rash or blisters) but many people do not show symptoms which means people often pass on STIs without realising it. Regular testing for STIs and HIV  is essential – everyone should have an STI screen, including an HIV test, at least once a year if having condomless sex with new or casual partners.

    Testing is free – including for students who have moved here from another country. It can be accessed through local sexual health clinics, university and college medical centres. Many sexual health services in England now offer free STI self-sampling kits for people who aren’t showing any symptoms or signs of an STI and would prefer a routine check-up in the comfort and privacy of their own home. If you notice any unusual symptoms, make sure to contact your local sexual health service and get tested.

    Laura Domegan, Head of Nursing at Brook, said:

    Freshers is always a good time for young people to consider their sexual health, with many of them moving away from home, meeting new people and taking part in all the fun that comes with starting a new college or university. This year it is particularly important, given the recent increase in diagnoses of several STIs, particularly among young people. Thankfully there are very simple steps everyone can take to look after themselves.

    Using condoms is one of the best ways to enjoy safer sex as they’re the only form of contraception that also protects against STIs. People should also get tested if they’ve had unprotected sex or started seeing a new partner. It doesn’t matter how many times you’ve had sex or how many sexual partners you’ve had, anyone can catch an STI. Many STIs do not have symptoms either, so testing is the only way to know if you have one or not.

    We would also encourage students to access their local sexual health services. They will be able to provide you with free condoms, contraception, and STI testing and treatment, as well as the confidential, non-judgement support you need to look after your sexual health. To find your nearest sexual health service visit the Brook Sexual Health Clinic Near Me website.

    UKHSA is also reminding students to ensure they are up to date with their free NHS vaccines, including:

    • MMR
    • MenACWY
    • HPV

    The MenACWY jab can be a lifesaver as it protects against some types of meningitis. The HPV vaccine protects against some forms of cancer and reduces the risk of genital warts. Some students will also be eligible for an mpox vaccine, a hepatitis B vaccine and a hepatitis A vaccine.

    UK Health Security Agency press office

    10 South Colonnade
    London
    E14 4PU

    Updates to this page

    Published 25 September 2024

    MIL OSI United Kingdom

  • MIL-OSI Economics: Tiff Macklem: Economic growth during uncertain times

    Source: Bank for International Settlements

    Good afternoon. I want to thank the Institute of International Finance and the Canadian Bankers Association for inviting me to take part in your 2024 Forum.

    Your focus on growth during uncertainty is timely. Uncertainty feels like the new reality: The uncertainty caused by war in Europe and in the Middle East. The uncertainties arising from geopolitical tensions and economic fragmentation. And the related uncertainties about supply chains, trading relationships and global investment risks.

    Rapid advances in new technologies, particularly artificial intelligence (AI) and its new offspring, Generative-AI, are disrupting business models and creating new uncertainties for firms and workers.

    Uncertainty surrounds the impacts of climate change and the policy frameworks to adapt to and mitigate it.

    There is political uncertainty. And fiscal uncertainty.

    As your theme implies, uncertainty and economic growth do not sit well together: uncertainty impedes growth.

    But with inspired policy, good business decisions and sound risk management, we can manage uncertainty and reduce its impact on households, businesses and growth. We have recent historical evidence.

    Sixteen years ago this month, Lehman Brothers failed, and the financial system froze because nobody knew which banks were safe. Today, the global financial system is much safer thanks to the implementation of sweeping global reforms to increase capital and liquidity buffers, and reduce leverage.

    With the rapid development of new vaccines and with exceptional fiscal and monetary policies, uncertainty about our health and the health of our economies has decreased dramatically since the depths of the COVID-19 pandemic.

    Thanks to decisive monetary policy action and the unblocking of supply chains, uncertainty about costs and inflation are much lower today than two years ago, when inflation peaked above 8% in Canada and was even higher in many other countries.

    In the past few weeks, I have given speeches on the shifting global trade landscape and the economic implications and risks of rapid advances in artificial intelligence. These are two key areas where we can reduce uncertainty through good policy and far-sighted business leadership.

    At the same time, we need to recognize that new uncertainties are a new reality, and we must be ready for the inevitable shocks in a more turbulent world. That puts a priority on risk management and investments in resilience.

    A key function of financial institutions is to help households and businesses manage the risks they face. Financial institutions also have a responsibility to manage their own risks prudently so that they do not themselves become a source of uncertainty and instability.

    As Canada’s central bank, we have a role to play in mitigating and managing risks and uncertainty. Our primary mandate is price stability-in other words, low, stable and predictable inflation. We also have mandates to foster a stable financial system and ensure safe and efficient payments.

    Let me say a few words on financial stability and payments. And then I’ll finish with some thoughts on monetary policy.

    Our financial stability focus is on risks that could lead to system-wide stress. And we publish these findings in our annual Financial Stability Report (FSR).1

    In our most recent FSR, published in May, we reported that Canadian mortgage holders had experienced a modest increase in levels of financial stress. Since then, we’ve observed that arrears on mortgages have continued to rise, although they remain below pre-pandemic levels. It also appears that these households have not leaned on revolving credit products such as lines of credit and credit cards to a greater degree than before the pandemic.

    But there is a notable increase in financial stress among borrowers without a mortgage, mainly renters. During the pandemic, for most credit products, the share of these borrowers missing payments reached historical lows. However, we’re now seeing a larger share of these borrowers lagging behind on credit card and auto loan payments. Over the past year the share of borrowers without a mortgage who carry a credit card balance of at least 90% of their credit limit has continued to climb. And this share is now above typical historical levels. This is concerning.

    Our responsibilities related to payments require us to adapt to increasing digitalization. Innovation in payments continues to accelerate.

    In 2021, the Bank assumed a new mandate for the supervision of retail payment service providers. Starting November 1st of this year, more than 3,000 service providers will need to register with the Bank and follow new rules aimed at safeguarding consumers and protecting the integrity of retail payments.  

    We are also looking at the bigger picture of payment innovation, both in Canada and around the world. As part of this work, in the past few years we’ve built an extensive body of knowledge about the framework and technology behind a possible central bank digital currency (CBDC), including the benefits and risks.

    But recognizing that there is not currently a compelling case to move forward with a CBDC in Canada, the Bank is scaling down its work on a retail central bank digital currency and shifting its focus to broader payments system research and policy development. The Bank will continue to monitor global retail CBDC developments. And the Bank will be ready to ensure Canadians always have a safe and secure supply of public money.

    Now, let me circle back to monetary policy.

    In June, we began lowering our policy interest rate. We cut the policy rate at our last three decisions, for a cumulative decline of 75 basis points to 4.25%.

    Our most recent decision on September 4th reflected two main considerations.

    First, we noted that headline and core inflation had continued to ease as expected. Second, we said that as inflation gets closer to target, we want to see economic growth pick up to absorb the slack in the economy.

    Since then, we’ve been pleased to see inflation come all the way back to the 2% target. It has been a long journey. Now we want to keep inflation close to the centre of the 1%–3% inflation-control band. We need to stick the landing.

    What does this mean for interest rates? With the continued progress we’ve seen on inflation, it is reasonable to expect further cuts in our policy rate. The timing and pace will be determined by incoming data and our assessment of what those data mean for future inflation.

    As always, we try to be as clear as we can about what we are watching as we chart the course for monetary policy.

    Economic growth picked up in the first half of this year, and we want to see it strengthen further so that inflation stays close to the 2% target. Some recent indicators suggest growth may not be as strong as we expected. We will be closely watching consumer spending, as well as business hiring and investment.

    We will also be looking for continued easing in core inflation, which is still a little above 2%. Shelter cost inflation remains elevated but has started to come down, and we are looking for it to moderate further.

    Our next decision is October 23rd. And we will have a revised economic outlook at that time.

    With those introductory thoughts, let’s get the discussion started.

    I would like to thank Russell Barnett, Claudia Godbout and Brian Peterson for their help in preparing these remarks.


    MIL OSI Economics

  • MIL-OSI Europe: Statement by Antonio Tajani, Minister for Foreign Affairs and International Cooperation of Italy in his capacity as Chair of the G7 Foreign Ministers’ Meeting at the High-Level Week of the UN General Assembly (23 September 2024)

    Source: Republic of France in English
    The Republic of France has issued the following statement:

    1. Introduction

    In today’s meeting in New York, in the wake of the Summit of the Future, the G7 Foreign Ministers of Canada, France, Germany, Italy, Japan, the United Kingdom, the United States and the High Representative of the European Union reiterated their commitment to upholding the rule of law, humanitarian principles and international law, including the Charter of the United Nations, and to protecting human rights and dignity for all individuals.

    They re-emphasized their determination to foster collective action in order to preserve peace and stability to address global challenges, such as the climate crisis and to advance the achievement of the 2030 Agenda for Sustainable Development and the Sustainable Development Goals (SDGs).

    In doing so, the G7 members renewed their commitment to the promotion of free societies and democratic principles, where all persons can freely exercise their rights and freedoms.

    2. Summit for the Future

    In the spirit of the renewed determination to strengthen the multilateral system based on the UN Charter’s principles, as reflected in the Pact for the Future adopted at the Summit of the Future by world Leaders, the G7 members committed to continue working with countries and all relevant stakeholders within the UN system through dialogue, mutual understanding and respect in the pursuit of common solutions, with the aim of upholding and reforming the multilateral system so that it better reflects today’s world and is fit to respond to the complex global challenges of the future. They reaffirmed their commitment to work with all UN member states to strengthen the roles of the UNSG as well as the UNGA. They also recommitted to the reform of the UNSC.

    3. Steadfast Support to Ukraine

    The G7 members reaffirmed their unwavering support to Ukraine as it defends its freedom, sovereignty, independence, and territorial integrity, against Russia’s brutal and unjustifiable war of aggression. The G7 members strongly condemned Russia’s blatant breach of international law, including the UN Charter, and of the basic principles that underpin the international order. They strongly condemned the serious violations of international humanitarian law perpetrated by Russia’s forces in Ukraine, which have caused a devastating impact on the civilian population. Violence against civilians, including women, children, and prisoners of war is unacceptable.

    They expressed their outrage at Russia’s repeated attacks against critical infrastructure and they condemned in the strongest possible terms any targeting of civilian buildings and even hospitals. Ensuring the protection and resilience of Ukraine’s energy grid and its power generation capacity remains a fundamental and urgent priority as winter approaches. They welcomed the international conference on energy security held on August 22. .as well as the ongoing coordination of the G7 energy group. They reiterated their commitment to help Ukraine meet its urgent short-term financing needs, as well as support its long-term recovery and reconstruction priorities.

    Russia must end its war of aggression and pay for the damage it has caused to Ukraine. The G7 members reiterated their commitment to explore and use all possible lawful avenues by which Russia is made to meet those obligations.

    The launch of the Extraordinary Revenue Acceleration (ERA) Loans for Ukraine, as mandated by G7 leaders, will make available approximately USD 50 billion in additional funding to Ukraine that will be serviced and repaid by future flows of extraordinary revenues stemming from the immobilization of Russian sovereign assets held in the European Union and other relevant jurisdictions.

    The G7 Foreign Ministers and the High Representative are working, together with Finance Ministers, to operationalize the G7 Leaders’ commitment by the end of the year. They will maintain solidarity in this commitment to providing this support to Ukraine. The G7 members confirmed that, consistent with all applicable laws and their respective legal systems, Russia’s sovereign assets in their jurisdictions will remain immobilized until Russia ends its aggression and pays for the damage it has caused to Ukraine.

    They also committed to strengthening the Ukraine Donor Platform to help coordinate the disbursal of funds and ensure they align with Ukraine’s highest priority needs at a pace it can effectively absorb. This will play a key role in advancing Ukraine’s reforms in line with its European path and in contributing to a successful Ukraine Recovery Conference to be held in Italy in 2025.

    Any use of nuclear weapons by Russia in the context of its war of aggression against Ukraine would be inadmissible. They therefore condemned in the strongest possible terms Russia’s irresponsible and threatening nuclear rhetoric, as well as its posture of strategic intimidation. They also expressed their deepest concern about the reported use of chemical weapons as well as riot control agents as a method of warfare by Russia in Ukraine.

    The G7 members remained committed to holding those responsible accountable for atrocities in Ukraine, in line with international law. They also condemned the seizures of foreign companies and called on Russia to reverse these measures and seek acceptable solutions with the companies targeted by them.

    They condemned Russia’s seizure and continued control and militarization of Zaporizhzhia nuclear power plant, which poses severe risks for nuclear safety and security, potentially affecting the entire international community. They reiterated their support to the International Atomic Energy Agency’s efforts directed at mitigating such risks.

    They underlined once again their support for Ukraine’s right of self-defense and reiterated their commitment to Ukraine’s long-term security, recalling the launch of the Ukraine Compact in Washington on 11 July 2024. They re-affirmed the intention to increasing industrial production and delivery capabilities to assist Ukraine’s self-defense. They highlighted their support to Ukraine in its efforts to modernize its armed forces and strengthen its own defense industry. They expressed their resolve to bolster Ukraine’s air defense capabilities to save lives and protect critical infrastructure.

    They remained committed to raising the costs of Russia’s war of aggression by building on the comprehensive package of sanctions and economic measures already in place. Though existing measures have had a significant impact on Russia’s war machine and ability to fund its invasion, its military is still posing a threat not just to Ukraine but also to international security.

    The G7 members expressed the intention to continue taking appropriate measures, consistent with their legal systems, against actors in China and in third countries that materially support Russia’s war machine, including financial institutions, and other entities that facilitate Russia’s acquisition of items for its defense industrial base.

    They expressed their intention to continue to apply significant pressure on Russian revenues from energy and other commodities. This will include improving the efficacy of the oil price cap policy by taking further steps to tighten compliance and enforcement, including against Russia’s shadow fleet, while working to maintain market stability.

    They especially emphasized the urgency to support Ukraine’s energy security, including by coordinating international assistance through the G7+Ukraine Energy Coordination Group. They underscored the importance to continue working with the Ukrainian authorities and International Financial Institutions through the Ukraine Donor Platform, and by mobilizing private investments and fostering participation of civil society.

    They highlighted the reality of millions of internally displaced Ukrainians and the importance of an inclusive rights-based, gender-responsive recovery, including the reintegration of veterans and civilians with disabilities, and to address the needs of women, children as well as other population groups who have been disproportionately affected by Russia’s war of aggression. They reiterated their condemnation of Russia’s unlawful deportation of Ukrainian children and welcomed coordinated efforts to secure their safe return. They called on Russia to release all persons it has unjustly detained and safely return all civilians it has illegally transferred or deported, starting with children. They welcomed the Ministerial Conference on the Human Dimension of Ukraine’s 10 point peace formula that will be hosted by Canada on October 30-31.

    They reiterated the need to support Ukraine’s agriculture sector, which is critical for global food supply, particularly for the most vulnerable nations, and called for unimpeded exports of grain, foodstuffs, fertilizers and inputs from Ukraine.

    They acknowledged the importance to involve the private sector in the sustainable economic recovery of Ukraine. They welcomed and underscored the significance of Ukraine itself continuing to implement domestic reform efforts, especially in the fields of anti-corruption, justice system reform, decentralization, and promotion of the rule of law. These endeavors are in line with the Euro-Atlantic path Ukraine has embraced. The G7 members were unanimous on the need to continue to support efforts of the Ukrainian government and people in these endeavors.

    They resolutely condemned Russia’s holding of illegitimate ‘elections’ in the occupied Ukrainian Autonomous Republic of Crimea and the city of Sevastopol. Russia’s actions once again demonstrate its blatant disregard for Ukraine’s territorial integrity, sovereignty and independence, and the UN Charter. They called on all members of the international community to refrain from recognizing Russia’s illegitimate actions.

    They welcomed the Summit on Peace in Ukraine that took place in Switzerland on June 15-16 and its focus on the key priorities needed to achieve a framework for peace based on international law, including the UN Charter and its principles, and respect for Ukraine’s sovereignty and territorial integrity. They remained committed to follow up on the Conference through constructive engagement with all international partners to reach a comprehensive, just and lasting peace.

    The G7 members acknowledged that Russia continues to expand its campaigns of foreign information manipulation and interference (FIMI). They condemned Russia’s use of FIMI to support its war of aggression against Ukraine. They reiterated their determination to bolster the G7 Rapid Response Mechanism by developing a collective response framework to counter foreign threats to democracies.

    4. Situation in the Middle East

    The G7 members reiterated their condemnation of Hamas’ horrendous attacks on October 7, 2023. 101 hostages are still in the hands of Hamas. They noted with deep concern the trend of escalatory violence in the Middle East and its repercussions on regional stability and on the lives of civilians shattered by this conflict, from the Gaza Strip to the Israeli-Lebanese Blue Line. Actions and counter-reactions risk magnifying this dangerous spiral of violence and dragging the entire Middle East into a broader regional conflict with unimaginable consequences. They called for a stop to the current destructive cycle, while emphasizing that no country stands to gain from a further escalation in the Middle East.

    They expressed their deep concern about the situation along the Blue Line. They recognized the essential stabilizing role played by the Lebanese Armed Forces and the UN Interim Force in Lebanon in mitigating that risk. They demanded the full implementation of UNSCR 1701 (2006) and urged that all relevant actors implement immediate measures towards de-escalation.

    The G7 members reaffirmed their strong support for the ongoing mediation efforts undertaken by the United States, Egypt and Qatar to reach a resolution between the parties to the conflict in Gaza. They reiterated their full commitment for the implementation of the UNSC Resolution 2735 (2024) and the comprehensive deal outlined by President Biden in May that would lead to an immediate ceasefire in Gaza, the release of all hostages, a significant and sustained increase in the flow of humanitarian assistance throughout Gaza, and an enduring end to the crisis, to secure a pathway to a two-state solution with a safe Israel alongside a sovereign Palestinian state. They urged the parties to the conflict to unequivocally accept the ceasefire proposal, stressing the need for countries in a position to directly influence the parties to cooperate in strengthening mediation efforts. They called for the full implementation of the terms of the ceasefire proposal without delay and without conditions.

    They called on all parties to fully comply with international law, including international humanitarian law. They expressed their deep alarm for the heavy toll this conflict has taken on civilians, deploring all losses of civilian lives equally and noting with great concern that, after nearly a year of hostilities and regional instability, it is mostly civilians, including women and children, who are paying the highest price. Protection of civilians must be an absolute priority for all parties at all times.

    The G7 members expressed concern at the unprecedented level of food insecurity affecting most of the population in the Gaza Strip. Securing full, rapid, safe, and unhindered humanitarian access in all its forms and through all relevant crossing points remains an absolute priority. They urged all parties to allow the unimpeded delivery of aid and ensure protection of humanitarian workers by properly implementing de-confliction measures. They recognized the crucial role played by UN agencies and other humanitarian actors in delivering assistance especially health care for the most vulnerable persons, including the polio vaccination campaign. They expressed their support for UNRWA to effectively uphold its mandate, emphasizing the vital role that the UN Agency plays.

    The G7 members reaffirmed their unwavering commitment, through reinvigorated efforts in the Middle East Peace Process, to the vision of a two-state solution where two democratic states, Israel and Palestine, live side by side in peace within secure and recognized borders, consistent with international law and relevant UN resolutions, and in this regard stress the importance of unifying the Gaza strip with the West Bank under Palestinian Authority. We note that mutual recognition, to include the recognition of a Palestinian state, at the appropriate time, would be a crucial component of that political process. They expressed their concern about the risk of weakening the Palestinian Authority and underlined the importance of maintaining economic stability in the West Bank. They welcomed the EU’s 400 million Euro emergency package for the Palestinian Authority. All parties must refrain from unilateral actions and from divisive statements that may undermine the prospect of a two-state solution, including the Israeli expansion of settlements and the “legalization” of settlement outposts. They condemned the rise in extremist settler violence committed against Palestinians, which undermines security and stability in the West Bank and threatens prospects for a lasting peace. They expressed their deep concern regarding the deteriorating security situation in the West Bank.

    They reiterated their commitment to working together – and with other international partners – to closely coordinate and institutionalize their support for civil society peacebuilding efforts, ensuring that they are part of a larger strategy to build the foundation necessary for a negotiated and lasting Israeli-Palestinian peace. The G7 members called on Iran to contribute to de-escalation of tensions in the region. They demanded that Iran cease its destabilizing actions in the Middle East. They underlined that they stand ready to adopt further sanctions or take other measures in response to further destabilizing initiatives.

    They reiterated their determination that Iran must never develop or acquire a nuclear weapon and that the G7 will continue working together, and with other international partners, to address Iran’s nuclear escalation. A diplomatic solution remains the best way to resolve this issue. As the IAEA remains unable to verify that Iran’s nuclear program is exclusively peaceful, they urged Iran’s leadership to cease and reverse nuclear activities that have no credible civilian justification and to cooperate with the IAEA without further delay to fully implement their legally binding safeguards agreement and their commitments under UNSCR 2231(2015).

    They condemned in the strongest possible terms Iran’s export and Russia’s procurement of Iranian ballistic missiles. Evidence that Iran has continued to transfer weaponry to Russia despite repeated international calls to stop represents a further escalation of Iran’s military support to Russia’s war of aggression against Ukraine. Russia has used Iranian weaponry such as UAVs to kill Ukrainian civilians and strike their critical infrastructure.

    They reiterated that Iran must immediately cease all support to Russia’s illegal and unjustifiable war against Ukraine and halt such transfers of ballistic missiles, UAVs and related technology, which constitute a direct threat to the Ukrainian people as well as European and international security more broadly.

    They reaffirmed their steadfast commitment to hold Iran to account for its unacceptable support for Russia’s illegal war in Ukraine that further undermines global security. In line with their previous statements on the matter, they underscored that they are already responding with new and significant measures.

    They also reiterated their deep concern about Iran’s human rights violations, especially against women and minority groups. They reiterated their call on Iran to allow access to the country to relevant UN Human Rights Council Special Procedures mandate holders.

    De-escalation efforts in the region must also include the immediate and unconditional termination of any attack by the Houthis against international and commercial vessels transiting the Gulf of Aden, the Bab al-Mandeb Strait and the Red Sea. The G7 members reiterated their strong condemnation of these attacks and the right of countries to defend their vessels from attacks. They called for the immediate release by the Houthis of the Galaxy Leader and its crew. They expressed their strong concern about the August 21 attack on the merchant vessel Sounion and the ongoing risk of an environmental catastrophe as salvage operations continue. They welcomed the efforts by the EU maritime operation Aspides and by the US-led Operation Prosperity Guardian to protect vital sea lanes. They appreciated the efforts of those countries that are committed to protect freedom of navigation and trade, as well as maritime security, in line with UNSCR 2722 (2024) and in accordance with international law.

    5. Fostering partnerships with African Countries

    The G7 members reaffirmed their commitment to support African nations in the pursuit of sustainable development as well as the creation of jobs and growth. The focus remains on fostering fair partnerships, built on shared principles, democratic values, local leadership, and practical initiatives.

    They reiterated their intention to align actions with the African Union’s Agenda 2063 and the specific needs of African countries, including plans to improve local and regional food security, infrastructure, trade, and agricultural productivity. They expressed their support for the implementation of the African Continental Free Trade Area, a crucial factor for Africa’s growth in the next decade.

    The G7 members emphasized the need to strengthen mutually beneficial cooperation with African countries and regional organizations. In addition to maintaining financial support for African nations, they expressed their determination to improve the coordination and effectiveness of G7 resources, mobilizing domestic resources and encouraging increased private investments.

    They welcomed the African Union’s permanent membership in the G20, and the creation of an additional Chair for Sub-Saharan Africa on the IMF Executive Board in November.

    They reaffirmed their commitment to the G20 Compact with Africa, a tool aimed at enhancing private investment, driving structural reforms, supporting local entrepreneurship, and fostering cooperation, particularly in the energy sector. The G7 Partnership for Global Infrastructure and Investment (PGII), and initiatives like the EU’s Global Gateway can contribute to promote sustainable, resilient, and economically viable infrastructure in Africa, ensuring transparency in project selection, procurement, and financing. In this framework, they welcomed Italy’s Mattei Plan for Africa.

    They recognized that sustainable development, peace and security and democracy go hand in hand, reaffirming their commitment to help African governments in strengthening democratic governance and respect for human rights, while addressing conditions conducive to terrorism, violent extremism, and instability.

    They expressed their deep concern about the destabilizing activities of the Kremlin-backed Wagner Group and other Russia-supported entities. They called for accountability for all those responsible for human rights violations and abuses.

    6. Indo-Pacific

    The G7 members reiterated their commitment to a free and open Indo-Pacific, based on the rule of law, which is inclusive, prosperous and secure, grounded on sovereignty, territorial integrity, peaceful resolution of disputes, fundamental freedoms and human rights. They reaffirmed the importance of working together with regional partners and organizations, notably the Association of Southeast Asian Nations (ASEAN). They reaffirmed their thorough support for ASEAN centrality and unity. They reaffirmed their intention to work to support Pacific Island Countries’ priorities, as articulated through the 2050 Strategy for the Blue Pacific Continent.

    As they seek constructive and stable relations with China, they recognized the importance of direct and candid engagement to express concerns and manage differences. They reaffirmed their readiness to cooperate with China to address global challenges. They expressed their deep concern at the China’s support to Russia. They called on China to step up efforts to promote international peace and security, and to press Russia to stop its military aggression and immediately, completely and unconditionally withdraw its troops from Ukraine. They encouraged China to support a comprehensive, just and lasting peace based on territorial integrity and the principles and purposes of the UN Charter, including through its direct dialogue with Ukraine. They also expressed their deep concern at China’s ongoing support for Russia’s defense industrial base, which is enabling Russia to maintain its illegal war in Ukraine and has significant and broad-based security implications. They called on China to cease the transfer of dual-use materials, including weapons components and equipment, that are inputs for Russia’s defense sector.

    They recognized the importance of China in global trade. However, they expressed their concerns about China’s persistent industrial targeting and comprehensive non-market policies and practices that are leading to global spillovers, market distortions and harmful overcapacity in a growing range of sectors, undermining our workers, industries and economic resilience and security, as well as impacting on currencies. The G7 members are not decoupling or turning inwards. They are de-risking and diversifying supply chains where necessary and appropriate and fostering resilience to economic coercion. They called on China to refrain from adopting export control measures, particularly on critical minerals, that could lead to significant supply chain disruptions. Together with partners, the G7 members will invest in building their respective industrial capacities, promote diversified and resilient supply chains, and reduce critical dependencies and vulnerabilities.

    They remained seriously concerned about the situation in the East and South China Seas and reiterated their strong opposition to any unilateral attempt to change the status quo by force or coercion. They reaffirmed that there is no legal basis for China’s expansive maritime claims in the South China Sea, and they reiterated their opposition to China’s militarization and coercive and intimidation activities in the South China Sea. They re-emphasized the universal and unified character of the United Nations Convention on the Law of the Sea (UNCLOS) and reaffirmed UNCLOS’s important role in setting out the legal framework that governs all activities in the oceans and the seas. They reiterated that the award rendered by the Arbitral Tribunal on 12 July 2016 is a significant milestone, which is legally binding upon the parties to those proceedings and a useful basis for peacefully resolving disputes between the parties. They reiterated their strong opposition to China’s dangerous use of coast guard and maritime militia in the South China Sea and its repeated obstruction of countries’ high seas freedom of navigation. They expressed deep concern about the dangerous and obstructive maneuvers, including water cannons and ramming, by the China Coast Guard and maritime militia against Philippines vessels.

    The G7 members reaffirmed that maintaining peace and stability across the Taiwan Strait is indispensable to international security and prosperity, and called for the peaceful resolution of cross-Strait issues. There is no change in the basic position of the G7 members on Taiwan, including stated One-China policies. They supported Taiwan’s meaningful participation in international organizations as a member where statehood is not a prerequisite and as an observer or guest where it is.

    They remained concerned by the human rights situation in China, including in Xinjiang and Tibet. They are also worried about the crackdown on Hong Kong’s autonomy and independent institutions, and ongoing erosion of rights and freedoms. They urged China and the Hong Kong authorities to act in accordance with their international commitments and applicable legal obligations.

    The G7 members strongly condemned North Korea’s continuing expansion of its unlawful nuclear and ballistic missile programs in violation of multiple UNSC resolutions and its continuous destabilizing activities. They reiterated their call for the complete denuclearization of the Korean Peninsula and demanded that North Korea abandons all its nuclear weapons, existing nuclear programs, and any other WMD and ballistic missile programs in a complete, verifiable and irreversible manner, in accordance with all relevant UNSC resolutions. They called on North Korea to return to dialogue to promote peace and stability in the Korean peninsula. They urged all UN Member States to fully implement all relevant UN Security Council resolutions. They reiterated their deep disappointment with Russia’s veto last March on the mandate renewal of the UNSC 1718 Committee Panel of Experts.

    They condemned in the strongest possible terms the increasing military cooperation between North Korea and Russia, including North Korea’s export and Russia’s procurement of North Korean ballistic missiles and munitions in direct violation of relevant UNSCRs, as well as Russia’s use of these missiles and munitions against Ukraine. They are also deeply concerned about the potential for any transfer of nuclear or ballistic missiles-related technology to North Korea, in violation of the relevant UNSCRs. They urged Russia and North Korea to immediately cease all such activities and abide by relevant UNSCRs. They urged North Korea to respect human rights, facilitate access for international humanitarian organizations, and resolve the abductions issue immediately.

    They called on China not to conduct or condone activities aimed at undermining the security and safety of our communities and the integrity of our democratic institutions, and to act in strict accordance with its obligations under the Vienna Convention on Diplomatic Relations and the Vienna Convention on Consular Relations.

    7. Regional Issues

    Venezuela

    The G7 members reiterated their deep concern about the situation in Venezuela, following the vote on July 28.

    They emphasized that the announced victory of Maduro lacks credibility and democratic legitimacy, as indicated by reports of the UN Panel of Experts and independent international observers as well as data published by the opposition. They underscored that it is essential for electoral results to be complete and independently verified to ensure respect for the will of the Venezuelan people.

    They expressed their outrage for the arrest warrant and constant threats to the security of Edmundo Gonzalez Urrutia, who decided to seek refuge in Spain. According to the above-mentioned independent reports, Edmundo Gonzalez Urrutia appears to have won the most votes.

    They urged Venezuelan representatives to cease all human rights violations and abuses, arbitrary detentions and widespread restrictions on fundamental freedoms, particularly affecting the political opposition, human rights defenders, and representatives of independent media and civil society. They called for the release of all political prisoners and for a path to freedom and democracy for the people of Venezuela.

    They urged the international community to keep Venezuela high on the diplomatic agenda and they expressed their support for efforts by regional partners to facilitate the Venezuelan-led democratic and peaceful transition that the people of Venezuela have clearly chosen in the polls.

    Haiti

    The G7 members expressed their determination to continue supporting Haitian institutions – including the Transitional Presidential Council (CPT) and the Government of Prime Minister Conille – in their commitment to create the necessary conditions of general security and stability for the convening, by February 2026, of free and fair elections. The expression of popular will would set the foundation for the full restoration of democracy and the rule of law in Haiti.

    They also expressed full support to the Multinational Security Support (MSS) mission, which is providing critical support to the Haitian National Police as they counter criminal gangs engaged in illicit trafficking and inflicting brutal violence upon the population.

    The G7 members emphasized the importance of continued support to the MSS mission through financial contributions to the UN Trust Fund as well as contributions in kind. They expressed their strong appreciation for the commitment of the Government of Kenya – which has already deployed 380 personnel on the ground – to support the Haitian National Police in restoring peace and security.

    They called on all countries that have committed to deploy their contingents to the MSS mission to do so as soon as possible, to consolidate the mission and its fundamental role in the Country. They called on Haiti’s partners to continue their humanitarian assistance to the Haitian people and to expedite their financial and in-kind contributions to the MSS mission to help ensure that the mission is resourced for success.

    They called also on the United Nations Security Council to consider a UN Peace Operation to maintain the security gains of the Haiti National Police and the MSS mission for holding free and fair elections and called on the Secretary-General accordingly to provide support.

    The G7 members welcomed the work of the G7 Working Group on Haiti in monitoring institutional, political, social and security developments in Haiti, with a view to supporting the stabilization of the country and the restoration of full democratic governance.

    Libya

    The G7 members reiterated their unwavering commitment to Libyan stability, sovereignty, independence and unity. They expressed deep concern about recent developments in the country, in particular those involving the leadership of the Central Bank of Libya and the High Council of State, which show the fragility and unsustainability of the present status quo. They urged relevant Libyan parties to rapidly reach the necessary compromises to begin to restore the institutional integrity of the Central Bank of Libya and its standing with the international financial community. They called on Libyan political actors to refrain from taking harmful unilateral actions that create further political tension and fragmentation and make the country vulnerable to harmful foreign interference.

    They noted advances made in the organization of local elections and they called for a free, fair and inclusive participation of all Libyans. It is now imperative to relaunch a Libyan-led and Libyan-owned political process facilitated by the UN towards free and fair presidential and parliamentary elections.

    They expressed their support and commended the efforts made by UNSMIL officer in charge Stephanie Koury in support of the stabilization of Libya. They called on the Secretary General to appoint a new Special Representative without delay.

    Sudan

    The G7 members reiterated their grave concern over the ongoing fighting, mass-displacement and famine in Sudan.

    They condemned the serious human rights violations and abuses against the civilian population, including widespread sexual and gender-based violence, as well as international humanitarian law violations by both sides to the conflict. They called for an immediate end to the escalating violence, which is creating further displacement, and urged the warring parties to ensure the protection of civilians. They reiterated their commitment to holding accountable all those responsible for violations of international law in Sudan.

    They condemned the emergence of famine in Sudan as a direct consequence of efforts to restrict access of humanitarian actors. They noted recent progress in relation to the re-opening of the Chad-Sudan Adre border crossing, in the wake of the Paris Conference and of the Geneva talks. They called for full, rapid, safe, and unhindered humanitarian access both into Sudan and across lines of conflict so aid can reach all those in need.

    They urged all parties to cease hostilities immediately and to engage in serious negotiations aimed at achieving a lasting ceasefire, humanitarian access and protection of civilians without pre-conditions.

    They called on external actors to refrain from fueling the conflict, to respect the UN arms embargo on Darfur, and to play a responsible role in resolving the crisis.

    They welcomed mediation efforts by regional and international actors and organizations to facilitate a durable peace for the country.

    Inclusive, national dialogue, aimed at restoring democracy, re-establishing and strengthening the civilian and representative institutions after the end of the conflict, is a prerequisite for lasting peace. The G7 Members emphasized that it is necessary for representatives of Sudanese civil society, including women, to be fully engaged in the reflection on the political future of the country.

    MIL OSI Europe News

  • MIL-OSI USA: Understanding Mosquito-Borne Diseases in Connecticut

    Source: US State of Connecticut

    Despite the gradual arrival of fall, mosquitos are still active in our state. Paulo Verardi, professor of virology and vaccinology and head of the Department of Pathobiology and Veterinary Science, shares information that can keep Connecticut residents safe from mosquito-borne diseases.

    What types of mosquito-borne diseases are we seeing in Connecticut?

    Mosquito-borne diseases are spread by the bite of infected mosquitoes. In Connecticut, one would immediately think of West Nile virus, by far the most common mosquito-borne virus in the region. However, we have

    additional viruses transmitted by mosquitoes, such as Eastern Equine Encephalitis (EEE) virus, Jamestown Canyon virus, and Cache Valley virus, that luckily are less common. Sometimes Connecticut has imported cases of additional mosquito-borne diseases, such as dengue fever and Zika virus disease. These are acquired when people travel to areas where the virus is circulating, get bitten by an infected mosquito, and then travel back to Connecticut. If you are traveling outside the country in areas like the Caribbean and Central or South America, you should also be aware of chikungunya virus, yellow fever virus, and Oropouche virus, to name a few.

    Why are these diseases appearing more frequently in the state?

    Cases are linked to the proliferation of mosquitoes, which is driven by several factors including precipitation and temperature patterns, as well as alterations in these patterns. Climatic changes seem to also be impacting the distribution of these diseases, especially because warmer temperatures can promote a wider geographical range of disease-transmitting mosquitoes.

    West Nile virus has been in Connecticut since 1999, when it was introduced in New York City, so it is relatively new. On the other hand, evidence of EEE in Massachusetts dates back almost 200 years, and thus it is considered a local disease. West Nile cases in people are not uncommon during every mosquito season, but EEE seems to be impactful only every few years, such as in 2019 when a larger outbreak last occurred.

    West Nile and EEE viruses are actually maintained in nature in reservoir hosts, typically birds, and therefore these are considered zoonotic diseases. This means that the interplay amongst people, animals, plants, and the environment is a major factor determining the prevalence and transmission of these diseases, in what we call the One Health concept.

    What times of year do we need to be concerned about mosquito-borne diseases?

    We ought to be concerned any time of the year when mosquitoes are up and about. Generally, we think of the hot summer months, but transmission can start in the spring and last well into the fall season. A good example is EEE, as cases typically peak in late summer, but transmission can occur as late as October.

    What are the symptoms of these diseases?

    Diseases like West Nile and EEE are caused by viruses, so flu-like symptoms are typical:  fever, headache, fatigue, and in some instances rashes. Most people may not even feel sick at all, while a few others may end up developing inflammation of the brain (encephalitis) or of the membranes around the brain and the spinal cord (meningitis), leading to severe disease symptoms.

    What should someone do if they are sick?

    First, never assume that you may just have a cold, and pay attention to the severity of your symptoms. Consult a health care provider if symptoms do not improve, particularly if you have high fever and headache. Go immediately to an emergency room if symptoms become severe and you suspect any neurological involvement. The key is to be vigilant and proactive.

    It is noteworthy that horses with EEE are severely affected with up to 95% mortality (about half that rate for West Nile fever), and routine vaccination of horses for both diseases is recommended.

    How dangerous/deadly are these diseases?

    Fortunately, for most of us infections are self-contained. Our immune system can keep the invading viruses in check, and all you may experience are mild flu-like symptoms, if any. But symptoms can be more severe and can worsen very quickly. Pay attention to any rashes or severe symptoms, such as high fever, intense headache, stiffness of the neck, and other neurological problems. Encephalitis and meningitis are dangerous and life-threating complications, so a visit to the emergency room is necessary at the onset of neurological signs.

    What actions are state and local governments taking to help?

    Connecticut’s Department of Public Health (DPH) and Department of Agriculture (DoAg) are monitoring the situation in Connecticut and surrounding states closely. The Connecticut Agricultural Experiment Station (CAES) is doing surveillance of mosquitoes, and the Connecticut Veterinary Medical Diagnostic Laboratory (CVMDL) at UConn is monitoring wild and domestic animals (mammals and birds). In some cases, agencies may decide to curtail outdoor activities in certain areas at dusk, as Connecticut did in 2019 when we had high activity of EEE in Eastern Connecticut CT and neighboring states, and mosquito spraying may be recommended in limited areas by the Connecticut’s Department of Energy and Environmental Protection (DEEP).

    How can Connecticut residents protect themselves and help stop the spread of these diseases?

    By preventing mosquito bites:

    • Avoid outdoor activities during dusk and dawn, when mosquitoes are most active
    • Use approved insect repellents
    • Wear long-sleeved shirts and pants when outside
    • Keep mosquitoes out of your house with the appropriate use of window and door screens.

    One can also treat clothing and gear with permethrin, which will help repel both mosquitoes and ticks. Vaccines against some mosquito-borne illnesses such as dengue, yellow fever, chikungunya, and Japanese encephalitis are available for people traveling to high-risk areas. Visit the Center for Disease Control and Prevention (CDC) Traveler’s Health site for further information.

    This work relates to CAHNR’s Strategic Vision area focused on Enhancing Health and Well-Being Locally, Nationally, and Globally.

    Follow UConn CAHNR on social media

    MIL OSI USA News

  • MIL-OSI USA: MetLife Stadium to Become a Mission Ready Venue, Serving as a Vital Location During Disasters and Part of NFL and FEMA’s National Strategy to Make Venues Mission Capable During Disasters

    Source: US Federal Emergency Management Agency

    Headline: MetLife Stadium to Become a Mission Ready Venue, Serving as a Vital Location During Disasters and Part of NFL and FEMA’s National Strategy to Make Venues Mission Capable During Disasters

    MetLife Stadium to Become a Mission Ready Venue, Serving as a Vital Location During Disasters and Part of NFL and FEMA’s National Strategy to Make Venues Mission Capable During Disasters

    New Jersey – Stadiums and venues provide a central and accessible location to help communities respond to extreme weather crises, providing safe storage and shelter in times of need. With these events becoming more frequent, severe, and expensive, FEMA Administrator Deanne Criswell and NFL Chief Security Officer Cathy Lanier today announced that MetLife Stadium in New Jersey, home of the New York Jets and New York Giants, will be among the first NFL venues to be designated as a Mission Ready Venue that can be used during response and recovery missions. Through Mission Ready Venues, a public-private partnership, MetLife Stadium will increase its capabilities to better sustain public safety and be a source of support for the community they serve. The designation identifies the ways MetLife Stadium could be used for response and recovery activities during declared emergencies or disasters.

    “We are honored that MetLife Stadium is one of the first NFL venues designated as a Mission Ready Venue,” said MetLife Stadium President and CEO Ron VanDeVeen. “The stadium will serve as a staging area and safe space that will offer critical support and comfort to our community in the event of a crisis.” 

    “During large-scale emergencies, like the COVID-19 pandemic, hurricanes, or tornados, we’ve seen how large music, sports and entertainment venues can serve as a safe space for communities,” said FEMA Administrator Deanne Criswell. “This new strategy we’re launching with the NFL is a groundbreaking opportunity to help our partners use these venues for emergency response and recovery needs, while keeping communities safe and making them more resilient. While we are starting with the NFL, all venues across sports organizations and leagues can become assets to their communities, and I encourage them to join in this collaborative effort as we grapple with the impacts of the climate crisis.”

    “Public-private partnerships are essential to helping communities during the response and recovery phases of a disaster,” said FEMA Region 2 Administrator David Warrington. “Establishing relationships of this type will not only enhance our nation’s resilience toward the disasters we face today but will be critical in shaping tomorrow due to the ever-changing landscape of emergency management. This collaborative effort with the NFL is a true reflection of whole-community engagement and I welcome the opportunities it will bring.”

    “Stadiums are valuable community assets that are often used in times of disasters,” said NFL Chief Security Officer Cathy Lanier. “This designation reflects the role that many stadiums play, not only on Sundays, but especially in times of need. We are proud to work with FEMA and first responders at the local and state level to ensure disaster response agencies have the information and tools they need to help a community recover when disaster strikes.” 

    According to the NYU School of Professional Studies and the U.S. Conference of Mayors, stadiums and arenas can improve the public health and well-being of their communities —including pandemic response during COVID-19. 

    “Collaborating with our Federal counterparts and the NFL to designate MetLife Stadium as a mission-ready venue for disasters highlights a critical step in strengthening our state’s emergency preparedness,” said Colonel Patrick J. Callahan, Superintendent of the New Jersey State Police and State Director of Emergency Management. “In times of crisis, every second counts. This partnership ensures we have a strategically located, fully equipped facility capable of supporting large-scale emergency operations, allowing us to respond swiftly and effectively to protect the lives and well-being of New Jersey’s residents.”

    Given the size, capabilities, and locations of large sports venues, these existing community assets can serve the public in a variety of ways including emergency shelters, staging areas, commodity distribution sites, evacuation pick up points, disaster recovery centers, mass vaccination and testing, temporary hospitals and more. FEMA and the NFL recognized this unique opportunity for collaboration and are enlisting the support of venue owners, operators, and the tenants of these facilities to work with government officials in the planning and preparation for emergency or disaster response and recovery efforts.  To receive an official Mission Ready Venue designation, venues must undergo a comprehensive assessment to determine what capabilities the venue may be able to support in emergency and disaster response and recovery efforts. The designation highlights the following attributes of selected venues: 

    • Provide Safety and Security: Stadiums are usually centrally located, close to major roadways and transportation hubs, and critical services like hospitals. If used to respond to a disaster, the designation will save valuable time and resources and will further enhance coordination between the public and private sectors during disaster response and recovery. 
    • Provide Accessibility: Stadiums are also compliant with Americans with Disabilities Act and can support persons with disabilities and others with access or functional needs. Additionally, 73% of NFL venues are accessible by mass transportation. This provides an avenue to promote equitable service to underserved populations to access potentially critical lifesaving/life sustaining services after an event.  
    • Strengthen Community Resilience: Stadiums and arenas are a focal point of communities and help strengthen social networks by enhancing connections between residents with home team pride. These Mission Ready Venues can boost morale amidst disaster. By providing a more robust and resilient environment, these venues can enhance social networks amongst survivors while providing ample opportunities to establish connections with the venue’s main tenants.
    • Ensure Unity of Effort: Coordination of stadium resources and services can support survivors and responders and help stabilize an incident quickly. Since stadiums are fixed locations, resources and services can be deployed quickly. This promotes the community’s physical and economic recovery.

    Mission Ready Venue designations are for five-year increments with a yearly check-in to ensure continued readiness of the venue. Redesignation will be necessary every five years and designation does not supersede any agreements with state, local or private sector entities.

    kate.macedo

    MIL OSI USA News

  • MIL-OSI Translation: Bronchiolitis in infants: how to protect yourself this winter?

    MIL OSI Translation. Government of the Republic of France statements from French to English –

    Source: Republic of France in FrenchThe French Republic has issued the following statement:

    Share the page

    Are you interested in this topic?

    Log in to your account and receive an email alert as soon as an article is published by the editorial staff on: Social, health (aid and benefits, disabled person, carers and mediators, patient, medication, etc.)

    Subscribe

    Your subscription has been taken into account

    You will be alerted by email as soon as an article is published by the editorial team on: Social, health (aid and benefits, disabled person, carers and mediators, patient, medication, etc.)

    You can cancel your subscription at any time in your account publicservice.fr .

    Childhood diseases

    Published on September 25, 2024 – Directorate of Legal and Administrative Information (Prime Minister)

    Every winter, bronchiolitis affects around 30% of newborns and infants. To prepare well, the Ministry of Labor, Health and Solidarity is strengthening its awareness campaign. What are the right actions to take and the treatments available? Service-Public.fr answers you.

    Image 1Credits: Kaspars Grinvalds – stock.adobe.com

    Aimed primarily at parents but also at everyone, this campaign reminds us the right gestures to adopt to limit contamination but also to be attentive and act if the first symptoms appear.

    Since the end of 2023, a vaccine for pregnant women and preventive treatments for infants have existed:

    An injection of the Abrysvo vaccine can be administered during pregnancy, between the 7th and 8th months. The vaccine allows the mother to develop antibodies that are transmitted directly to the child, who will be immunized from birth to the first 6 months; 2 preventive treatments can be given to the infant: Synagis, intended for premature or high-risk newborns with heart or lung malformations; Beyfortus, intended for newborns and infants under 1 year old.

    These products are available in pharmacies and maternity wards (except Synagis, available only in maternity wards).

    They are 100% covered by health insurance, subject to some specificities.

    Namely

    80% of parents have received treatment since its introduction and around 5,800 hospitalizations for bronchiolitis have been avoided.

    See also

    EDITOR’S NOTE: This article is a translation. Apologies should the grammar and/or sentence structure not be perfect.

    MIL Translation OSI

  • MIL-OSI Africa: South African women face exclusion from society due to gender-based violence – how they’re fighting back

    Source: The Conversation – Africa – By Amanda Gouws, Professor of Political Science and Chair of the South African Research Initiative in Gender Politics, Stellenbosch University

    When South Africa became a democracy in 1994, a primary goal was to grant citizenship rights to all its people, in particular, to give the majority black South Africans rights they had been denied during colonialism and apartheid. This included the right to vote.

    Apartheid segregated the population into ethnic groups. All but people classified as white were stripped of their rights. The 1996 constitution conferred upon citizens civil liberties such as the right to vote, movement, association and free speech as well as substantive rights such as access to land, health, education and employment.

    But, as I argue in the Palgrave Handbook of Gender and Citizenship, full citizenship is about more than a legal status that grants rights. Full citizenship also means being able to fully participate in a society.

    Based on my research into South African politics and gender politics over the past three decades I argue in a recent chapter that women in South Africa don’t enjoy full citizenship because they face endemic gender-based violence.

    Sexual violence against women has become normalised in South Africa. Everyday spaces are filled with violence, as indicated by the South African Police Service’s quarterly crime statistics.

    I conclude in the book chapter that people who feel excluded turn to protest to claim their rights as citizens. In doing so they become activist citizens.

    Acts of citizenship can occur in many different places – on streets, in courts, at borders, or even through media. They can happen on different scales, from local community action to international movements. These acts may involve protests, organising campaigns, or using digital media to spread awareness. People engaging in these acts might demand a wide range of rights, including political, social, sexual, ecological, or cultural rights.


    Read more: Gender apartheid: oppression of women should be made a crime against humanity – feminist academic explains why


    While legal frameworks to enhance citizenship have changed over the past 30 years in South Africa, deep-seated inequalities and exclusions persist. Law reform cannot address high levels of unemployment (that need to be rectified through economic growth), neither can it address poverty that is endemic because of the legacies of apartheid, such as the exclusion from decent education and health care.

    Acts of citizenship – whether through protest (such as service delivery protest), art, or everyday actions – continue to play a crucial role in expanding the boundaries of who is considered a citizen and what rights citizens can claim.

    By understanding citizenship as something that is actively performed and claimed, rather than simply granted, society can better appreciate the ongoing struggles for equality and recognition.

    Acts of citizenship

    Emotions play a significant role in these citizenship actions, a concept known as “affective citizenship”. Expressions of fear, happiness, loneliness, anger, or grief can all be part of how people assert their rights and demand recognition. These emotional displays can be disruptive or more conventional, but they all focus on exclusions from citizenship.

    Some acts of citizenship involve a “politics of refusal” – rejecting unfair conditions or norms. This refusal can expose hidden issues within citizenship, such as specific forms of gendered violence or discrimination. By disrupting “business as usual”, these acts force society to confront uncomfortable truths.

    It’s important to note that acts of citizenship aren’t always large-scale or dramatic. They can also involve everyday actions that challenge norms or assert rights in smaller ways. What matters is that these acts transform the actors from passive subjects into active citizens claiming their rights.

    Examples include the #EndRapeCulture campaign of 2016, when women protested against pervasive sexual violence on university campuses. At the same time, transgender students also protested against marginalisation.

    Both groups of students used naked protests to show their refusal to be treated as though they were not citizens. Through their campaign, the students rejected behaviour and attitudes that normalise sexual violence on campuses.

    Women students disrupted public spaces by protesting topless or in their underwear, sometimes brandishing sjamboks (plastic whips). These actions expressed anger at university authorities’ failure to address sexual violence. The activists were refusing to be treated as though they were not citizens.

    By using their bodies in these acts of citizenship the protesters made visible the rage many South African women feel about sexual violence committed with seeming impunity. They highlighted how women’s bodies are vulnerable to violence due to neglect by authorities in implementing their own laws, such as the Sexual Offences Act and the Domestic Violence Act.


    Read more: Victory for women’s rights in Ghana as affirmative action law is passed – what must happen next


    For its part the Trans Collective, a group of transgender students at the University of Cape Town, used a provocative art intervention to highlight the erasure or the making invisible of transgender experiences within the broader student movement during the same 2016 period.

    They smeared red paint on photographs at an exhibit about student activism and used their naked, paint-covered bodies to block the entrance of the art gallery at the university to force visitors to confront the physical reality of how transgender rights are often “trampled” or ignored, even within progressive movements.

    Impact

    Acts of citizenship – whether through naked protests, art interventions, or other forms of activism – serve multiple purposes:

    • They make visible groups and issues that are overlooked or deliberately ignored.

    • They challenge conventional understandings of how citizens should behave or what citizenship looks like.

    • They create new spaces for political action and discourse.

    • They force society and authorities to confront uncomfortable truths about exclusion and violence.

    • They assert the agency of marginalised groups in defining and claiming their rights.

    – South African women face exclusion from society due to gender-based violence – how they’re fighting back
    – https://theconversation.com/south-african-women-face-exclusion-from-society-due-to-gender-based-violence-how-theyre-fighting-back-237493

    MIL OSI Africa

  • MIL-OSI Global: South African women face exclusion from society due to gender-based violence – how they’re fighting back

    Source: The Conversation – Africa – By Amanda Gouws, Professor of Political Science and Chair of the South African Research Initiative in Gender Politics, Stellenbosch University

    When South Africa became a democracy in 1994, a primary goal was to grant citizenship rights to all its people, in particular, to give the majority black South Africans rights they had been denied during colonialism and apartheid. This included the right to vote.

    Apartheid segregated the population into ethnic groups. All but people classified as white were stripped of their rights. The 1996 constitution conferred upon citizens civil liberties such as the right to vote, movement, association and free speech as well as substantive rights such as access to land, health, education and employment.

    But, as I argue in the Palgrave Handbook of Gender and Citizenship, full citizenship is about more than a legal status that grants rights. Full citizenship also means being able to fully participate in a society.

    Based on my research into South African politics and gender politics over the past three decades I argue in a recent chapter that women in South Africa don’t enjoy full citizenship because they face endemic gender-based violence.

    Sexual violence against women has become normalised in South Africa. Everyday spaces are filled with violence, as indicated by the South African Police Service’s quarterly crime statistics.

    I conclude in the book chapter that people who feel excluded turn to protest to claim their rights as citizens. In doing so they become activist citizens.

    Acts of citizenship can occur in many different places – on streets, in courts, at borders, or even through media. They can happen on different scales, from local community action to international movements. These acts may involve protests, organising campaigns, or using digital media to spread awareness. People engaging in these acts might demand a wide range of rights, including political, social, sexual, ecological, or cultural rights.




    Read more:
    Gender apartheid: oppression of women should be made a crime against humanity – feminist academic explains why


    While legal frameworks to enhance citizenship have changed over the past 30 years in South Africa, deep-seated inequalities and exclusions persist. Law reform cannot address high levels of unemployment (that need to be rectified through economic growth), neither can it address poverty that is endemic because of the legacies of apartheid, such as the exclusion from decent education and health care.

    Acts of citizenship – whether through protest (such as service delivery protest), art, or everyday actions – continue to play a crucial role in expanding the boundaries of who is considered a citizen and what rights citizens can claim.

    By understanding citizenship as something that is actively performed and claimed, rather than simply granted, society can better appreciate the ongoing struggles for equality and recognition.

    Acts of citizenship

    Emotions play a significant role in these citizenship actions, a concept known as “affective citizenship”. Expressions of fear, happiness, loneliness, anger, or grief can all be part of how people assert their rights and demand recognition. These emotional displays can be disruptive or more conventional, but they all focus on exclusions from citizenship.

    Some acts of citizenship involve a “politics of refusal” – rejecting unfair conditions or norms. This refusal can expose hidden issues within citizenship, such as specific forms of gendered violence or discrimination. By disrupting “business as usual”, these acts force society to confront uncomfortable truths.

    It’s important to note that acts of citizenship aren’t always large-scale or dramatic. They can also involve everyday actions that challenge norms or assert rights in smaller ways. What matters is that these acts transform the actors from passive subjects into active citizens claiming their rights.

    Examples include the #EndRapeCulture campaign of 2016, when women protested against pervasive sexual violence on university campuses. At the same time, transgender students also protested against marginalisation.

    Both groups of students used naked protests to show their refusal to be treated as though they were not citizens. Through their campaign, the students rejected behaviour and attitudes that normalise sexual violence on campuses.

    Women students disrupted public spaces by protesting topless or in their underwear, sometimes brandishing sjamboks (plastic whips). These actions expressed anger at university authorities’ failure to address sexual violence. The activists were refusing to be treated as though they were not citizens.

    By using their bodies in these acts of citizenship the protesters made visible the rage many South African women feel about sexual violence committed with seeming impunity. They highlighted how women’s bodies are vulnerable to violence due to neglect by authorities in implementing their own laws, such as the Sexual Offences Act and the Domestic Violence Act.




    Read more:
    Victory for women’s rights in Ghana as affirmative action law is passed – what must happen next


    For its part the Trans Collective, a group of transgender students at the University of Cape Town, used a provocative art intervention to highlight the erasure or the making invisible of transgender experiences within the broader student movement during the same 2016 period.

    They smeared red paint on photographs at an exhibit about student activism and used their naked, paint-covered bodies to block the entrance of the art gallery at the university to force visitors to confront the physical reality of how transgender rights are often “trampled” or ignored, even within progressive movements.

    Impact

    Acts of citizenship – whether through naked protests, art interventions, or other forms of activism – serve multiple purposes:

    • They make visible groups and issues that are overlooked or deliberately ignored.

    • They challenge conventional understandings of how citizens should behave or what citizenship looks like.

    • They create new spaces for political action and discourse.

    • They force society and authorities to confront uncomfortable truths about exclusion and violence.

    • They assert the agency of marginalised groups in defining and claiming their rights.

    Amanda Gouws receives funding from the NRF through her SARChI Chair in Gender Politics.

    ref. South African women face exclusion from society due to gender-based violence – how they’re fighting back – https://theconversation.com/south-african-women-face-exclusion-from-society-due-to-gender-based-violence-how-theyre-fighting-back-237493

    MIL OSI – Global Reports

  • MIL-OSI Canada: Federal government launches Health Emergency Readiness Canada to strengthen preparedness for future health emergencies

    Source: Government of Canada News (2)

    New agency will provide sustained focus on growing innovation and industrial capacity in the life sciences and biomanufacturing sector to support Canada’s health emergency readiness

    New agency will provide sustained focus on growing innovation and industrial capacity in the life sciences and biomanufacturing sector to support Canada’s health emergency readiness

    September 24, 2024 – Ottawa, Ontario 

    The COVID-19 pandemic has had devastating effects on Canadians and their livelihoods. That’s why the federal government is taking action to be better prepared for future health emergencies and build a stronger life sciences ecosystem in Canada.

    Today, the Honourable François-Philippe Champagne, Minister of Innovation, Science and Industry, and the Honourable Mark Holland, Minister of Health, jointly announced the launch of Health Emergency Readiness Canada (HERC), a new federal organization within Innovation, Science and Economic Development Canada dedicated to protecting Canadians against future pandemics and delivering on Canada’s life sciences and medical countermeasures readiness objectives.

    HERC will serve as Canada’s focal point to help mobilize industry to respond in a coordinated approach to public health needs and to support the growth of a domestic life sciences sector. This new organization will bridge the gap between research and commercialization, meaning Canadians could get faster access to the most relevant and effective vaccines, therapeutics, diagnostics and other products, including when they need them the most.

    Once HERC is fully operational, its key features are expected to include:

    • integrated decision making to build life sciences capacity
    • strengthened partnerships with industry, academia and international counterparts
    • the development and maintenance of a Canadian industrial game plan to mobilize research and industry in the event of a health emergency
    • world-leading innovation to advance next-generation technology platforms

    With the creation of this new agency, Canada joins G7 peers that have created specialized entities to support health emergency readiness, following similar initiatives such as the United States’ Biomedical Advanced Research and Development Authority (BARDA) and the EU’s Health Emergency Preparedness and Response Authority (HERA).

    Media Relations
    Innovation, Science and Economic Development Canada
    media@ised-isde.gc.ca

    MIL OSI Canada News

  • MIL-OSI Translation: Federal government launches Health Crisis Preparedness Canada to help country prepare for future health emergencies

    MIL OSI Translation. Canadian French to English –

    Source: Government of Canada – in French

    The new agency will focus on strengthening innovation and industrial capacity in the life sciences and biomanufacturing sector to help Canada prepare for health emergencies.

    The new agency will focus on strengthening innovation and industrial capacity in the life sciences and biomanufacturing sector to help Canada prepare for health emergencies.

    September 24, 2024 – Ottawa, Ontario

    The COVID-19 pandemic has had a devastating impact on Canadians and their livelihoods. The Government of Canada is taking action to ensure the country is better positioned to respond to future health emergencies, including by building a more robust life sciences ecosystem.

    Today, the Minister of Innovation, Science and Industry, the Honourable François-Philippe Champagne, and the Minister of Health, the Honourable Mark Holland, jointly announced the creation of Health Crisis Preparedness Canada (HCPC), a new federal agency within Innovation, Science and Economic Development Canada that will work to protect Canadians from future pandemics and help the country achieve its medical countermeasures and life sciences goals.

    PCSC will become a national hub for engagement, facilitating the coordination of industry efforts in response to public health needs, while supporting the growth of the national life sciences sector. This new organization will bridge the gap between research and commercialization, ensuring that Canadians can access the most effective vaccines, therapeutics, diagnostics and other products more quickly, particularly when they are needed most.

    When the body is fully operational, it will:

    will integrate decision-making processes to strengthen the capacity of the life sciences sector; strengthen its partnerships with industry, academia and international organizations with a similar mandate; develop and maintain an industrial action plan to mobilize the research sector and industry in the event of a health emergency; and support world-class innovations that will position Canada as a leader in next-generation technology platforms.

    In establishing this body, Canada is following in the footsteps of other G7 countries that have established specialized health emergency preparedness entities, including the Biomedical Advanced Research and Development Authority in the United States and the European Health Emergency Preparedness and Response Authority.

    Audrey MilettePress SecretaryOffice of the Minister of Innovation, Science and Industryaudrey.milette@ised-isde.gc.ca

    Media RelationsInnovation, Science and Economic Development Canadamedia@ised-isde.gc.ca

    EDITOR’S NOTE: This article is a translation. Apologies should the grammar and/or sentence structure not be perfect.

    MIL Translation OSI

  • MIL-OSI USA: Durbin, Wicker Introduce Resolution Commemorating the 30th Anniversary Of the Eradication Of Polio In The Americas

    US Senate News:

    Source: United States Senator for Illinois Dick Durbin

    09.24.24

    WASHINGTON – U.S. Senate Majority Whip Dick Durbin (D-IL) and U.S. Senator Roger Wicker (R-MS) today introduced a resolution commemorating the 30th anniversary of the eradication of polio in the Americas, in which the World Health Organization (WHO) certified the region as being “polio-free” on September 29, 1994.  Nearly 60,000 children in the United States were reported to have polio in 1952, with more than 20,000 cases of paralysis.  The polio vaccine was discovered at the University of Pittsburgh in Pennsylvania by Jonas Salk and his research team between 1952 and 1953.  The resolution is cosponsored by U.S. Senators Jack Reed (D-RI), Kyrsten Sinema (I-AZ), Amy Klobuchar (D-MN), Ron Wyden (D-OR), Tim Kaine (D-VA), Chris Van Hollen (D-MD), Patty Murray (D-WA), Peter Welch (D-VT), and Cory Booker (D-NJ).

    “Polio is a cruel disease, one that has historically caused considerable pain here in the United States, and abroad,” Durbin said. “But thanks to the effort of groups like Chicago’s Rotary International, today, polio remains endemic in only two countries worldwide: Afghanistan and Pakistan.  The complete worldwide eradication of polio is imminently achievable.  I’m pleased to introduce this resolution with my colleague, Senator Wicker, recognizing the important achievements we have made and urging a sustained commitment to finally eradicate this disease once and for all.”

    “We are closer than ever to eliminating polio – thanks in part to consistent U.S. investments over the last 30 years. I will continue working to build on this momentum and strengthen eradication-initiatives, especially in Afghanistan and Pakistan,”Wicker said.

    “The Shot@Life campaign thanks Senators Durbin and Wicker for introducing this bipartisan Resolution and for their longstanding leadership in the fight to end polio,” said Cara Ciullo, Senior Director for Shot@Life.  “The Global Polio Eradication Initiative is a critical leader in the global effort to ensure children everywhere have access to polio vaccinations.  U.S. government support for these activities protects vulnerable children and strengthens global health security, keeping Americans safe at home and abroad.”

    “Rotary is delighted to see this resolution highlighting progress toward ending polio,” said Michael McGovern, Chair of Rotary’s International PolioPlus Committee. “While we celebrate the fact that the Americas have been polio free for more than a generation, we can’t become complacent. Polio anywhere is a risk everywhere. A polio free world is Rotary’s top priority and we are grateful for continued US leadership toward that shared goal.”

    In the resolution, the Senators highlight Rotary International, an international association founded in 1905 in Chicago, Illinois, and now headquartered in Evanston, Illinois, which has made eradicating polio globally one of its top priorities.  Rotary International has been a key contributor to reducing outbreaks of polio worldwide, including contributing more than $2.7 billion in the global fight against polio.  Since 1988 the number of cases of polio around the world has been reduced by 99 percent, as a result of the efforts and support from Rotary International, WHO, the Bill and Melinda Gates Foundation, the United Nations Children’s Fund (UNICEF), the United Nations Foundation, the United States, and other national governments.

     Text of the resolution can be found here.

    -30-



    MIL OSI USA News

  • MIL-OSI United Kingdom: Thousands of deaths could be avoided with new vaccine Older people should take a new vaccine to protect them against Respiratory Syncytial Virus (RSV) according to new research from the University of Aberdeen and the MRC-University of Glasgow Centre for Virus Research.

    Source: University of Aberdeen

    Older person being vaccinatedOlder people should take a new vaccine to protect them against Respiratory Syncytial Virus (RSV) according to new research from the University of Aberdeen and the MRC-University of Glasgow Centre for Virus Research.

    In new research published in Age & Ageing today, a team of scientists led by Professor Roy Soiza, Consultant Geriatrician and Honorary Chair at the University reviewed the evidence on the safety and effectiveness of vaccines against RSV in older and frailer individuals. They found the vaccines to be 86 percent effective in preventing RSV-related lower respiratory tract infections in the first year after vaccination. 

    If uptake of the vaccine reaches 70 percent, evidence suggests that up to 2,800 deaths could be prevented in the UK every year.  Additionally, with at least 70 percent uptake, around 36,000 GP consultations, 4,600 hospitalisations and 1,000 ICU admissions could be avoided.   

    However, the authors warn of a culture of ‘vaccine fatigue’ as well as ‘vaccine hesitancy’ which could impact on the numbers of older people accepting the vaccine.  

    The review paper comes in response to the UK launch of a new vaccination programme against RSV for 75 to 79-year-olds. Known to cause serious lung infections in very young infants, there is growing evidence that RSV can also cause serious chest infections in the elderly population contributing to an estimated 8000 deaths and 175,000 GP interventions every year in the UK.  

    Professor Roy Soiza who led the research at the University of Aberdeen explains: “The NHS is badly stretched, so efforts to reduce the healthcare burden from avoidable communicable diseases such as RSV infection are highly desirable. Although some sections of social media are often dominated by anti-vaccine messages, it is important that reliable public health messages cut through the noise. 

    “Our review found that the vaccines are safe and effective and we are calling on healthcare professionals and carers to encourage those invited to receive the vaccine to take up the opportunity.   

    “There is evidence of effectiveness in preventing RSV-related lower respiratory tract infections of around 86 percent in the first year after vaccination.  

    “Trials have been conducted in people aged over 60 years of age, including those with underlying medical conditions, but the number of volunteers aged 80 or over was too small to be certain of the extent of benefit. Nevertheless, we saw in the covid pandemic that the effectiveness of vaccines in trials of younger and healthier people was replicated in those who were much frailer and older.   

    “We therefore urge those with an interest in the care of older people to encourage those eligible and invited to have the new vaccine to take it.” 

    Dr Sam Ghebrehewet, Head of Immunisation and Vaccination at Public Health Scotland, said: “The recent launch of Scotland’s new RSV vaccination programme marks another significant step forward to protect the health of the population.    

    “RSV can be very serious for those who are more vulnerable, such as older adults. In recent years, we’ve seen an increase in those aged 75 years and over being hospitalised for RSV. That’s why we’re asking all those who are eligible for the RSV vaccine to take up the offer to protect themselves against the more serious complications of an RSV infection.” 

    Antonia Ho, Professor of Infectious Diseases at the MRC-University of Glasgow Centre for Virus Research, who collaborated on the research said: “The availability of the first effective RSV vaccines in the UK is really exciting. Along with existing influenza and covid-19 vaccines, they will allow us to protect vulnerable groups from serious lung infections, and reduce the enormous pressures faced by the NHS in the winter months. 

    “The vaccination catch-up campaign for 76 to 79 years is due to end on 30 September 2024 and I would urge those who are eligible to attend their vaccination appointment.”

    Our review found that the vaccines are safe and effective and we are calling on healthcare professionals and carers to encourage those invited to receive the vaccine to take up the opportunity.” Professor Roy Soiza

    To find out how you can help support medical research at the University of Aberdeen please contact giving@abdn.ac.uk. If you would prefer to make a gift of your time, please contact alumni@abdn.ac.uk to find out more about our alumni volunteering opportunities.

    MIL OSI United Kingdom

  • MIL-OSI Russia: Sobyanin: Lomonosov Cluster Plays Leading Role in Import Substitution Development

    MIL OSI Translation. Region: Russian Federation –

    Source: Moscow Government – Government of Moscow –

    The need for import substitution has become one of the drivers for the development of Moscow production. Work in this direction was discussed by in his blog Sergei Sobyanin.

    “Our comprehensive business support system is designed to provide all necessary assistance to new developments and production of domestic products. The leading role in this matter is given to

    cluster “Lomonosov”, the operator of which is Moscow Innovation Cluster“, the Mayor of Moscow wrote.

    The new building of the scientific valley of the Moscow State University named after M.V. Lomonosov has allowed to unite the most promising innovations of the capital. All necessary conditions for the operation of high-tech productions have been created here.

    More than 60 companies have become residents of the cluster since 2023. They develop high-tech solutions for the medical, space, oil and gas, food and other industries.

    More than two thousand people are employed in production. The enterprises’ revenues exceeded 11 billion rubles last year. They have access to support from the entire innovation ecosystem of the capital, including the “Academy of Innovators” – one of the most successful projects of the capital Department of Entrepreneurship and Innovative Development, which helps develop projects from an idea to a startup.

    Powerful controllers, efficient filters and software for pharmaceuticals

    The developments of the residents of the Lomonosov cluster successfully compete with both domestic and foreign analogues.

    For example, the company “Adaptto” produces controllers – electronic devices for controlling the electric drive of vehicles. Compact and functional devices are two to four times more powerful than similar imported devices. They are used in all types of electric transport (in land, air, water transport), as well as in industry (fans, elevators).

    The company plans to complete new developments in the near future. These include a three-in-one unit (controller, inverter, gearbox) for electric vehicles and hybrid power plants.

    “Pharmaceutical and microelectronic production requires a particularly clean air environment – there literally shouldn’t be a speck of dust in the room,” noted Sergei Sobyanin.

    Aerolife specialists have developed a fundamentally new type of filters. Innovative filters allow achieving the highest level of purification according to class U15. Air is purified by 99.9995 percent with a size of polluting particles greater than 0.1 micrometer. The products have no analogues in Russia, and imported ones are inferior in such characteristics as dust capacity and energy efficiency.

    Aerolife systems are used at microprocessor manufacturing plants in Zelenograd, in the development of new drugs at institutes of the Russian Academy of Sciences, in the production of vaccines at the N.F. Gamaleya National Research Center for Epidemiology and Microbiology (NRCEM), and at more than 20 pharmaceutical companies.

    Serial production of new filters has been launched in the Mosgormash technology park. This year, the company plans to triple its capacity.

    The Simurg computing platform, created by Simurgpharm, is the first drug development software in Russia. It can be used to analyze and predict preclinical and clinical data during drug planning and testing.

    The use of such mathematical models is a mandatory condition for registering new drugs. The platform is registered in the register of domestic software. It was tested jointly with specialists from the companies “Alpharma”, “Biocad” and others and is actively used in educational programs of the First Moscow State Medical University named after I.M. Sechenov and the Scientific and Technological University “Sirius”.

    Wireless communications, seismological equipment and protective coatings

    INWAVE (OOO Microwave Electronics) is a leading domestic manufacturer of control and measuring equipment, wireless communications and antenna systems. Wireless communications solutions include broadband access, radio relay and satellite communications.

    “The company’s technologies are successfully used in the development and production of various radio-electronic products, such as onboard equipment for space systems. Over the past year, with the support of the city, the company has increased its production capacity and is also planning to improve the line of control and measuring equipment, introducing new technologies and materials, which will improve the characteristics and reliability of the products,” the Mayor of Moscow said.

    The Split company produces a hardware and software complex using SplitMultiSeis technology. The system helps to conduct high-quality seismic research on land and at sea. It is used to solve engineering and geological problems, for example, when developing offshore fields or in transition zones. With the help of the complex, more than 100 projects have been implemented in the Arctic seas of Russia, the Black, Caspian, Baltic, Japanese seas, Onega and Ladoga lakes, Lake Baikal and others.

    OOO TSZP develops and implements technologies for surfacing and spraying multifunctional protective coatings from metals, ceramics and metal ceramics. Such coatings allow to extend the service life of products by three to four times, reduce the costs of major repairs by 30 percent and increase the interval between repairs of equipment, as well as provide a sufficient reserve of time for technical re-equipment of enterprises.

    “Innovative technologies for repair and strengthening of hot gas path elements of turbines from General Electric, Siemens, Ansaldo and others, which have successfully replaced foreign analogues, play a major role in import substitution. Over the past year alone, about 300 gas turbine parts have been restored for Moscow enterprises, and five research projects have been conducted to create import-substituting technologies,” wrote Sergei Sobyanin.

    The company’s customers include enterprises in the energy, oil, gas, oil refining, metallurgy, shipbuilding, aircraft manufacturing and other industries.

    Sergei Sobyanin: The Lomonosov Cluster has united the best innovators of the capital

    Please note: This information is raw content directly from the source of the information. It is exactly what the source states and does not reflect the position of MIL-OSI or its clients.

    Please note; This information is raw content directly from the information source. It is accurate to what the source is stating and does not reflect the position of MIL-OSI or its clients.

    https://vvv.mos.ru/major/themes/11748050/

    EDITOR’S NOTE: This article is a translation. Apologies should the grammar and or sentence structure not be perfect.

    MIL OSI Russia News

  • MIL-OSI USA: FACT SHEET: The United  States Commitment to Address the Global Mpox  Outbreak

    US Senate News:

    Source: The White House
    “Now we face the mpox outbreak in Central and Eastern Africa. Mpox is different from COVID-19. But we will act quickly – and bring partners with us. We are prepared to commit at least $500 million – to support African countries to prevent and respond to mpox and donate up to one million doses of mpox vaccines. We call on governments, charities, and businesses to match our pledge – and make this a $1 billion commitment to the people of Africa.” —President Biden, September 24, 2024
    The United States has led global efforts to combat infectious diseases, including mpox, for decades. Most recently in 2022, the Biden-Harris Administration mounted a robust response to the spread of clade IIb mpox by making vaccines available to those at risk, making testing more convenient, and providing treatments to those who needed them both in the United States and worldwide. In response to the ongoing mpox outbreak in Eastern and Central Africa, with several cases outside the region, the United States is acting quickly and decisively to support the response, and to prepare for potential cases domestically. On September 16, the White House welcomed key partners and community stakeholders working on mpox in the United States and around the world to a roundtable with U.S. Government leadership to exchange ideas, feedback and recommendations to inform the U.S. response to this global crisis.
    This week, President Biden announced that the United States is committed to providingat least $500 million dollars, as well as one million mpox vaccine doses, to support African countries to prevent and respond to the current mpox outbreak. These investments will be delivered both bilaterally, through existing relationships with partner countries, as well as through multilateral institutions. United States investments in mpox preparedness and response will address a range of needs outlined in the Mpox Continental Preparedness and Response Plan jointly issued by the Africa Centers for Disease Control and Prevention (Africa CDC) and the World Health Organization (WHO), including training frontline health workers, disease surveillance, laboratory diagnostic supplies and testing, clinical case management, risk communication and community engagement, infection prevention and control, and research. In addition to financial support and vaccines, the U.S. Government has surged dozens of staff, including epidemiologists, laboratorians, and risk communication experts to offer support to the mpox response in DRC and each of the countries surrounding DRC.
    BUILDING STRONGER, RESILIENT HEALTH SYSTEMS
    Investments in building stronger health systems are essential to a rapid and effective emergency response. Longstanding United States support, including through the President’s Emergency Plan for AIDS Relief (PEPFAR), helped to strengthen the systems that are now supporting the mpox response.
    Ongoing global health and health security investments. Since the start of the Biden-Harris Administration, the United States has provided more than $50 billion to support global health and health security. The United States is the largest health donor in the Africa region, allocating more than $2.65 billion in bilateral health funding to countries in Central and Eastern Africa in FY 2023 alone.
    Global health security partnerships. In April 2024, the United States announced formal global health security partnerships with 50 countries, including Burundi, DRC, Kenya, and Uganda. Global health security investments make it possible for the United States to address country-identified gaps in their capacity to prevent, detect, respond to, and recover from health security threats. U.S. assistance to the government of DRC, which began in 2015, has bolstered the DRC’s efforts to contain five Ebola outbreaks since 2020, develop an antimicrobial stewardship work plan, and develop a community feedback system to address infectious disease threats.
    President’s Emergency Plan for AIDS Relief (PEPFAR). For over 20 years, PEPFAR has supported more than 55 countries worldwide, saved more than 25 million lives, enabled 5.5 million babies to be born HIV-free, and prevented millions of new HIV infections. Longstanding PEPFAR investments in creating sustainable HIV care platforms have been leveraged for quick and effective response to cholera, COVID-19, Ebola, H1N1 influenza, tuberculosis, and other health threats. Given the increased risk of severe morbidity and mortality from mpox among people living with HIV, PEPFAR is ensuring program continuity to protect people living with HIV through the use of existing PEPFAR platforms through risk communication, laboratory and surveillance capacity, referral to care, HIV testing, and vaccination delivery to help prevent and respond to mpox.
    SUPPORTING MPOX TESTING, VACCINATION, TREATMENT AND CARE
    Mpox vaccine research and development. Since 2007, the United States, through the Department of Health and Human Services (HHS), has invested more than $2 billion in the JYNNEOS vaccine as part of smallpox preparedness. Additionally, U.S. Government research institutions led the development of the JYNNEOS vaccine through preclinical evaluation, clinical trials, and advanced clinical evaluation platforms. These investments directly led to product licensure for both smallpox and mpox. On September 13, WHO announced pre-qualification of the JYNNEOS vaccine for global use, including in the Africa region in response to ongoing mpox outbreaks.
    Mpox vaccine donation. This week President Biden pledged that the United States will donate up to one million doses of the mpox vaccine. The first U.S.-donated vaccine doses arrived in Nigeria in August (10,000 doses), and in DRC in September (50,000 doses). The next installment of the U.S. commitment, 300,000 vaccine doses, will be available immediately for disbursement in coordination with Gavi, the Vaccine Alliance and the WHO Access and Allocation Mechanism. Additional mpox vaccine doses will be delivered in tranches (totaling up to one million) pending country progress in administering the vaccines, in coordination with Gavi.
    Clinical care and protecting health workers. In DRC, the U.S. Government has procured and delivered medical kits containing antibiotics, oral hydration, and wound care supplies to support government facilities to offer mpox patients relief from their symptoms free of charge, which bolsters community trust and connection with the health care system. The U.S. Government is expanding health care worker capacity to treat mpox and offer psychosocial support to patients, while simultaneously training the workers to protect themselves through use of infection prevention and control best practices.
    Diagnostic tests and training. The U.S. Government is also supporting mpox-affected countries with laboratory expertise and diagnostic supplies. This includes: providing over 40,000 individual test assays and reagents that ensured that countries in the region had the capacity to detect clade I mpox when it crossed their borders; training dozens of laboratory personnel on the use of mpox test kits and procedures to enhance laboratory safety, hygiene, and waste management; strengthening the reach and availability of rapid diagnostic testing capacity; expanding specimen transportation routes; and establishing platforms for laboratory data management.
    Development and testing of effective therapeutics. The United States Government is leading the ongoing “Study of Tecovirimat for Human Mpox Virus” clinical trial for mpox treatment in the United States and other countries affected by clade II mpox.
    Identifying mpox research priorities. To help prioritize mpox research, the United States released an update on mpox research priorities, focusing on four objectives: (1) increasing knowledge about the biology of all clades, including how the virus is transmitted and how people’s immune systems respond to it; (2) evaluating dosing regimens of current mpox vaccines to stretch the vaccine supply and developing novel vaccine concepts; (3) advancing existing and novel treatments, including antivirals and monoclonal antibodies; and (4) supporting strategies for detecting the virus to facilitate clinical care and epidemiological surveillance.
    LEVERAGING STRONG MULTILATERAL PARTNERSHIPS
    As with investments in health systems, building stronger and more effective multilateral institutions between emergencies is essential to ensuring the world is prepared to respond effectively in times of crisis. The United States supports the critical roles of WHO and Africa CDC in leading the mpox response, and we call on those institutions to utilize the strong partnerships that are already in place, including with other multilateral institutions, to protect the health and wellbeing of people living in the affected countries.
    World Health Organization. Among his first acts in office, President Biden declared the United States would reengage with WHO, highlighting our nation’s commitment to advancing multilateral cooperation in a global health crisis. Beyond health emergencies, the United States is collaborating with WHO on a wide range of global health issues such as childhood immunization, nutrition, polio eradication, and strengthening the global health workforce to achieve universal health coverage. Since the beginning of the Biden-Harris Administration, the United States has provided nearly $1.9 billion of support to WHO. In addition, since March 2024, the United States has already provided more than $7.7 million to WHO to support mpox response activities, and $450,000 for building sustainable capacity for mpox elimination in DRC, Burundi, Central African Republic, Republic of Congo, Rwanda, and Uganda. 
    Africa CDC. The United States welcomes and supports the role of Africa CDC as a continent-wide public health institution, established in 2016. In 2022, the U.S. Government signed a Memorandum of Cooperation to Promote Public Health Partnership with the African Union, accompanied by a U.S.-Africa CDC Joint Action Plan outlining shared global health priorities and areas for collaboration. In addition to substantial U.S. bilateral and multilateral support aligned with Africa CDC’s five-year strategic plan and Agenda 2063, the United States provided more than $3 million in direct support to the Africa CDC in the form of in-kind assistance last year alone.
    Gavi, the Vaccine Alliance. Gavi holds essential expertise in effective vaccine procurement, distribution, and administration, which should be leveraged immediately in the mpox response. Since its inception in 2000, the United States Government has invested or announced: 1) over $3.6 billion to improve equitable access to new and underutilized vaccines in low- and middle-income countries; 2) a $4 billion dollar contribution to Gavi’s COVAX Advance Market Commitment; 3) an annual contribution to Gavi’s core budget, including $300 million in 2024 ; 4) and pledged at least $1.58 billion towards USG’s first-ever five-year pledge to Gavi’s next replenishment cycle, subject to Congressional approval. U.S. funding is included in Gavi’s $500 million First Response Fund, which is supporting procurement, delivery, and deployment of 500,000 JYNNEOS doses in response to the mpox outbreak. Finally, affected countries, WHO, Africa CDC, and Gavi recently established the Access and Allocation Mechanism (AAM) as a platform to increase equitable access to mpox response resources and contributions.
    The Quad. The Quad partnership was established in 2020 between the United States, India, Japan and Australia as a global force for good, including working together to help partners address pandemics and disease. During a September 21 Quad Summit, leaders agreed to coordinate efforts to promote equitable access to safe, effective, quality-assured mpox vaccines, including where appropriate expanding vaccine manufacturing in low and middle-income countries.
    Coalition for Epidemic Preparedness Innovations (CEPI). CEPI is working to accelerate the development of life-saving vaccines against emerging disease threats, and to transform capability for rapid countermeasure development in response to future threats.To date, the U.S. Government has invested $117 million through CEPI to accelerated the development of vaccines and other biologic countermeasures against epidemic and pandemic threats. CEPI has funded two scientific studies in Africa (the DRC and Uganda) focused on the JYNNEOS vaccine; it has also supported early clinical development of BioNTech’s next-generation mRNA-based pox vaccine and providing funding to support Bavarian Nordic’s MVA-BN® mpox vaccine clinical trials in DRC, Uganda, and Nigeria through the SMART trial.
    The Global Fund to Fight AIDS, Tuberculosis and Malaria. The Global Fund is working to defeat HIV, TB and malaria and ensure a healthier, safer, more equitable future for all. The U.S. is the largest donor to The Global Fund, and President Biden led the largest Global Fund replenishment ever in 2022. In August 2024, in response to the evolving mpox outbreak, the Global Fund quickly pivoted to update its guidance in order to direct grant funds to help eligible countries to prevent, detect, and respond to mpox outbreaks. Earlier this month, Global Fund committed an additional $9.5 million to support DRC’s mpox response.
    UNICEF. As the lead UN agency for children, UNICEF works in over 190 countries to save children’s lives and to support health and development. To date, the U.S. has provided UNICEF with more than $1.4 million to support clade I mpox preparedness and response activities in DRC, Burundi, and the Republic of Congo. UNICEF supports risk communication and community engagement, clinical services, psychosocial support, and coordination.
    United Nations High Commission for Refugees (UNHCR). As the lead UN agency for refugees, UNHCR provides vital protection and assistance to refugees, asylum-seekers, internally displaced and stateless people. Through UNHCR, the United States has provided nearly $9 million in humanitarian assistance this year to address urgent mpox-related needs among refugees, internally-displaced persons, host communities and other vulnerable populations in 14 countries throughout Africa.
    International Federation of Red Cross and Red Crescent Societies (IFRC). IFRC is the world’s largest humanitarian network working in more than 190 countries through a network of more than 16 million volunteers. To date, the U.S. Government has provided IFRC with $800,000 to support clade I mpox preparedness and response activities in DRC. IFRC supports risk communication and community engagement, clinical services, psychosocial support, and coordination.
    EXPANDING HEALTH EMERGENCY FINANCING
    In addition to ongoing bilateral and multilateral support to build stronger health systems, respond to ongoing health challenges, and pivot to address the current mpox crisis, the United States supports expanded sources of financing for response to health emergencies. Many of these have been developed and launched since the COVID-19 pandemic to address gaps identified through that response.
    The Pandemic Fund. As the only multilateral fund fully focused on prevention and preparedness, the Pandemic Fund has a critical role to play in building capacity to end the current outbreak and prevent the next one. The Pandemic Fund has taken quick action to support mpox preparedness efforts, approving $129 million to support 10 countries impacted by the disease to strengthen laboratory, surveillance, and human resources capacities. The selected projects meet needs articulated in the joint WHO-Africa CDC Mpox Continental Preparedness and Response Plan for Africa. The awards will be implemented over multiple years enabling an effective transition from crisis to long term preparedness. To continue its critical work, the Pandemic Fund is engaged in a concurrent resource mobilization round, with the goal of raising at least $2 billion in new funding through 2026. The United States has committed to provide up to $667 million, subject to Congressional appropriations and the availability of funds.
    Gavi’s Day Zero Financing Facility. The United States has supported Gavi, the Vaccine Alliance in establishing the Day Zero Financing Facility, a suite of tools that will mobilize, for example, up to $2 billion in risk-tolerant surge and contingent capital to enable Gavi to quickly meet the demand for vaccines in a pandemic.
    U.S. Development Finance Corporation (DFC) Health Emergency Financing: The DFC finances private-sector led solutions to health services, supply chain, and technology challenges in low- and middle-income countries. These solutions improve health system resilience and pandemic preparedness through: 1) a $1 billion-dollar rapid financing facility applicable to a full spectrum of vaccines (COVID-19, childhood vaccine-preventable diseases, and future outbreaks); 2) investments in regional, Africa-based vaccine manufacturing, including Aspen Pharmacare (South Africa) and Institute Pasteur de Dakar (Senegal); and 3) a G7 Surge Financing Initiative for Medical Countermeasures that supports Gavi and regional vaccine manufacturers.
    Multilateral development bank (MDB) evolution. MDBs have a key role to play in helping countries address global challenges, such as climate change, pandemics, and fragility and conflict. The United States is working with other shareholders to evolve the visions, incentive structures, operational approaches, and financial capacity of the MDBs to equip these institutions to respond to global challenges with sufficient speed and scale. The United States is pleased to see the close coordination between the World Bank, IMF, and regional development banks with WHO and affected countries on how to best utilize or reprogram resources to aid the mpox response.
    —-
    To learn more about mpox, its signs and symptoms, vaccines, prevention, and treatments, please visit the U.S. CDC website.

    MIL OSI USA News

  • MIL-OSI USA: Podcast: Fall and Winter Respiratory Ailments Await

    Source: US State of Connecticut

    These days, the question “Cold or flu?” doesn’t quite cover it when we start coughing and sneezing in the fall or winter.

    COVID-19 is still here, and we also have to deal with respiratory syncytial virus (RSV), in addition to pneumonia, bronchitis, and sinus infections, and even bird flu is starting to take hold in some parts of the world.

    The good news is, even if we can’t immediately tell these respiratory illnesses apart, the steps we can take to reduce the chances of spreading them apply broadly, namely hand-washing, staying home when sick, masking when symptomatic, and, most importantly for some of the viruses, vaccination.

    When we think about respiratory viruses, really vaccines are becoming a critical part of our toolkit in preventing infections, particularly among those who are at the highest risk for more severe infections. &#8212 Dr. David Banach

    UConn Health infectious diseases experts Nancy Dupont and Dr. David Banach explain on the UConn Health Pulse podcast.

    Listen now:

    Read transcript.

    MIL OSI USA News