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Category: Health

  • MIL-OSI Global: NIH funding cuts will hit red states, rural areas and underserved communities the hardest

    Source: The Conversation – USA – By Prakash Nagarkatti, Professor of Pathology, Microbiology and Immunology, University of South Carolina

    Protesters on the University of Illinois Chicago campus raise concerns over funding cuts for medical research on Feb. 19, 2025. Scott Olson via Getty Images

    The National Institutes of Health is the largest federal funder of medical research in the U.S. NIH funds drive research and innovation, leading to better understanding and treatment of diseases and improved health outcomes.

    The NIH provided more than US$35 billion in grants to over 2,500 universities and other institutions in 2023 to support biomedical research. Thus, it came as a shock to these institutions when the NIH, based on a new Trump administration policy, announced on Feb. 7, 2025, that it intends to cut the funding used to support the grantee institutions by $5.5 billion annually.

    On March 5, a U.S. district judge in Boston issued a nationwide injunction blocking the administration from implementing the proposed cuts to NIH funding, arguing that the planned cuts were unlawful. However, the White House will almost certainly appeal.

    We are a husband-and-wife team of immunologists who have been funded by the NIH for several decades. We believe our research has led to a better understanding of inflammatory and autoimmune diseases. In addition, one of us (Prakash Nagarkatti) served as vice president for research at the University of South Carolina for over a decade, managing all NIH grants awarded to the university.

    While we believe such cuts will be detrimental to the entire country, they will disproportionately hurt states that traditionally have received very low levels of NIH funding, the majority of which are red states that supported Trump’s election to a second term. This is because such states lack resources to develop advanced research infrastructure necessary to compete nationally for NIH funding.

    Several Republican senators have vocally opposed the funding cuts, including Susan Collins of Maine, who said they “would be devastating, stopping vital biomedical research and leading to the loss of jobs.”

    Support for cancer, Alzheimer’s research

    NIH funding is crucial for advancing biomedical research, improving public health and fostering innovation. It has a broad impact on different facets of society.

    The agency funds biomedical research leading to the development of vaccines or new drugs to prevent and treat infectious diseases and clinical disorders. The NIH played a crucial role in funding research on pandemics and global health crises caused by HIV/AIDS and COVID-19.

    In addition, the NIH supports advanced research in focused areas such as cancer, through the establishment of designated centers that offer cancer prevention, diagnosis, clinical trials and advanced treatment. Each year, approximately 400,000 patients receive cancer diagnoses and treatment at such centers.

    Similarly, the NIH supports research in other focused areas, such as Alzheimer’s disease, through the establishment of specialized research centers.

    The NIH also supports Small Business Innovation Research and Small Business Technology Transfer opportunities. These programs stimulate technological innovation by funding small businesses to commercialize new research ideas.

    Moreover, the agency provides funding to train the next generation of biomedical scientists, clinicians and public health professionals. Thus, the NIH awards create jobs at universities, biotechnology companies and related industries. Together, such NIH programs promote local and national economies.

    In 2024, NIH funding generated an estimated US$92 billion in economic activity. Every $100 million in NIH funding generates 76 patents, which creates $598 million in further research and development, as reported by NIH.

    Therefore, any cuts to the agency’s budget will have far-reaching and significant consequences on health outcomes and the economy.

    How the NIH funding process works – and how the cuts will affect research.

    Caps on indirect costs

    When the NIH awards grants, it is divided into two separate categories: the direct costs, which include expenses that are necessary to pursue the proposed work and that are provided to the scientists, and the indirect costs. These cover expenses such as maintenance of lab space, utilities, grant management, federal regulatory compliance, security and other miscellaneous needs. These funds are provided directly to the institution.

    Indirect costs are negotiated between the institution and the federal agency and expressed as a percentage of the direct costs. Because each institution has unique operational expenses, the indirect cost rates vary from 30% to 70%.

    The new policy rolled out by the NIH capped the indirect costs for all institutions at a fixed rate of 15%. In 2023, NIH spent $35 billion to support research at various institutions, of which $9 billion was used to cover indirect costs. Thus, NIH estimates it could save $4 billion by capping indirect costs at 15%.

    Inside an NIH lab in Bethesda, Md., where researchers work on treatments and cures for disease, including cancer.
    Saul Loeb/AFP via Getty Images

    How red states get hurt the most

    There is a significant geographic disparity in NIH funding that most people are unaware of. There are 27 states in the U.S. that receive 94% of NIH funding, while the other 23 states receive only 6%. Moreover, the NIH funding received by the 23 states has remained relatively unchanged for the past 20  years.

    There are many reasons why the latter states are less competitive. These include: lack of large medical centers, hospitals and research-intensive universities; thin and more rural populations; less robust economies; and lack of cutting-edge research infrastructure driven by less investment by the states in research and development.

    It is for these reasons that Congress in 1993 authorized the NIH to start a new program called the Institutional Development Award, or IDeA, to support the 23 states plus Puerto Rico that have traditionally received low levels of NIH funding. Such states are commonly called IDeA states and contain predominantly rural and medically underserved communities.

    These awards, which constitute less than 1% of the total NIH budget, are expected to help these states grow their research infrastructure and make them more competitive nationally.

    The IDeA states are: Alaska, Arkansas, Delaware, Hawaii, Idaho, Kansas, Kentucky, Louisiana, Maine, Mississippi, Montana, Nebraska, Nevada, New Hampshire, New Mexico, North Dakota, Oklahoma, Rhode Island, South Carolina, South Dakota, Vermont, West Virginia, and Wyoming, plus Puerto Rico. All the states but Delaware, Hawaii, Maine, New Hampshire, New Mexico, Rhode Island and Vermont voted for Trump in the 2024 election.

    Indirect costs pay for cutting-edge technologies

    Indirect costs, in addition to supporting the management of specific grants, are also helpful in promoting the institutions’ research infrastructure.

    The indirect costs help purchase and upgrade state-of-the-art research equipment and technologies. They help institutions develop high-performance computing facilities that are critical for research missions and provide access to journals and books through the library facilities. These costs also renovate old labs and help create new cutting-edge facilities such as germ-free facilities for microbiome research.

    Thus, the indirect costs are critical for IDeA states that have limited resources such as state support for pursuing research.

    According to the Higher Education Research and Development Survey, in 2023, non-IDeA states like California invested $548 million and New York over $303 million in R&D. In contrast, IDeA states Kentucky and West Virginia invested $49 million and $15 million, respectively, in R&D.

    Such data clearly demonstrates how challenging it would be for IDeA states to face cuts in NIH funding and advance research infrastructure.

    In our view, it is critical that all states have access to NIH research funding to enable the states to solve the unique challenges they face, such as environmental issues and population health disparities.

    For example, biomedical scientists and clinicians trained by NIH grants are addressing locally relevant issues such as coal workers’ pneumoconiosis, commonly known as black lung disease, which occurs when coal dust is inhaled. This is an occupational hazard linked to the coal industry in West Virginia and Kentucky.

    Similarly, Hawaii, with its tropical climate, has mosquitoes that can carry dengue virus, so dengue infection can pose a unique health and economic problem for this state when compared with the others in the U.S.

    Training the biomedical workforce and physicians in IDeA states also helps with retaining health providers in the state to further address these local challenges and prevents brain-drain to other non-IDeA states.

    IDeA states heavily rely on NIH funds to pursue and advance their research capabilities and address local and general health challenges. For such states, already struggling to receive NIH funding, reducing indirect costs would further exacerbate their disadvantages, increasing the risk of falling behind in medical research, patient care and regional economic growth.

    Prakash Nagarkatti receives funding from NIH.

    Mitzi Nagarkatti receives funding from NIH.

    – ref. NIH funding cuts will hit red states, rural areas and underserved communities the hardest – https://theconversation.com/nih-funding-cuts-will-hit-red-states-rural-areas-and-underserved-communities-the-hardest-250592

    MIL OSI – Global Reports –

    March 8, 2025
  • MIL-OSI United Kingdom: The Council commissions the Activation of Active Travel Programme

    Source: City of Preston

    Preston City Council has successfully commissioned the Activation of Active Travel Programme to four local providers who will support residents to become happier and healthier as they get more active through cycling, wheeling and walking.

    The funding was secured from Lancashire County Council to improve walking, cycling and wheeling facilities with the aim of boosting these forms of active travel.

    The Active Travel programme aims to put in place measures to support and encourage residents to change their behaviour and use existing active travel infrastructure. It will support Preston in achieving its priorities by helping residents, particularly underrepresented groups, to do more cycling, wheeling and walking for everyday journeys.

    The scheme also advances the Council’s Community Wealth Building strategy by enabling collaborative work with local partners to encourage residents to use local assets for community and environmental benefit.

    County Councillor Michael Green, Cabinet member for Health and Wellbeing at Lancashire County Council, said:

    Lancashire County Council allocated £30,000 to support this project, which aims to enhance targeted infrastructure such as cycle lanes, junction improvements, and pavements.

    These improvements align with Lancashire’s Local Cycling and Walking Infrastructure Plans and Highway Masterplan. The project aims to improve access to walking, cycling and wheeling modes of travel, such as wheelchairs and mobility scooters, particularly for hard-to-reach groups who are less likely to engage in physical activity. This initiative is fantastic for the overall health and wellbeing of the community.

    Preston has a large amount of public green spaces ideal for cycling and walking such as Avenham Park, Moor Park and The Guild Wheel.

    Further developments and public realm improvements such as the new tram bridge and Queen’s Street cycle route are also ongoing, funded by central government.

    Councillor Zafar Coupland, Preston City Council Cabinet Member for Health and Wellbeing said:

    This is a wonderful initiative encouraging Preston residents to make the most of the incredible spaces we have on our doorstep. Not only, will this programme encourage people to become more active, but it will also give residents the opportunity to discover places they may not have been to before.

    Together, these projects will build the confidence and skills of residents in the city supporting them to take part in cycling, wheeling and walking. They will particularly target underrepresented and vulnerable groups such as ethnic minority communities, those living in socio-economically deprived communities, and those with a disability or long-term health condition.

    The Activation programme comprises of three projects and four delivery partners:

    Supporting cycle commuting

    This project will be delivered by Preston Pedals, a community organisation that promotes a culture of everyday cycling in Preston for proven benefits for health and wellbeing, as well as tackling climate change.

    Dr. Julie Ridley, Co-director of Preston Pedals Ltd. said:

    Preston Pedals are excited to be awarded the grant for cycle commuting. We’re looking forward to working with volunteer Ride Buddies who will be trained as ride leaders, and we’ll support them to buddy others to cycle more. 

    Together we’ll create commuting routes for everyday cycling on quieter and off road in different parts of Preston, test them out, then turn these user-friendly routes into digital and paper maps for more people to use.

    Accessible cycling events

    This project will be delivered by Wheels for All, who currently have a Hub at UCLan Sports Arena and provide inclusive cycling sessions that embrace all children and adults with disabilities and differing needs to engage with quality cycling activity, using adapted cycles such as handcycles, trikes and wheelchair transporters to assist in building confidence and independence in cycling.

    Ian Tierney, CEO of Wheels for All said:

    Wheels for All is really excited to be part of the Preston Active Travel scheme. Our programme will consist of a series of outreach accessible cycling activities across the city of Preston giving people all abilities the chance to enjoy accessible cycling in their local communities.

    Widening Participation in Walking

    This project will be delivered by Preston Muslim Forum and Lancashire Teaching Hospitals NHS Foundation Trust.

    Preston Muslim Forum seeks to improve the lives and wellbeing of black, Asian and ethnic minority communities in the inner wards of Preston by fostering understanding and co-operation and providing training and skills.

    Lancashire Teaching Hospitals NHS Foundation Trust will support staff, patients and carers to get out for regular walks around Preston and Chorley and South Ribble Hospitals by providing training to walking leaders.

    Neil Pease, Chief People Officer at Lancashire Teaching Hospitals, said:

    We are delighted to have been successful in our bid for funding from Lancashire County Council’s Active Travel Scheme. Our colleagues told us that they would like to increase the amount of physical activity they do at work – and our new walking scheme will be the perfect way to do this.

    As part of the new walking scheme, we will develop a network of trained walk leaders who will help our colleagues to participate in a planned programme of regular walking activities. Our walk leaders will be organising and leading short, pre-planned lunchtime walks around local routes, which will help our colleagues to build their confidence and enjoy the many benefits of exercise as part of their daily lives.

    Thank you to the County Council for enabling us to offer this fantastic opportunity, which we believe has the potential to make a big difference to the health and wellbeing of many colleagues.

    The Active Travel programme promises to be a positive addition to the existing schemes that are already on offer in Preston such as free tennis lessons and football sessions, which have been a proven success in various parks across Preston.

    Additional Information

    Preston City Council actively applies and prioritises the principles of Community Wealth Building wherever applicable and appropriate. Community Wealth Building is an approach which aims to ensure the economic system builds wealth and prosperity for everyone.   

    MIL OSI United Kingdom –

    March 8, 2025
  • MIL-OSI Global: Beyond AI regulation: How government and industry can team up to make the technology safer without hindering innovation

    Source: The Conversation – USA – By Paulo Carvão, Senior Fellow, Mossavar-Rahmani Center for Business and Government, Harvard Kennedy School

    One of President Donald Trump’s first executive orders in his second term called for developing an AI action plan. Photo by Anna Moneymaker/Getty Images

    Imagine a not-too-distant future where you let an intelligent robot manage your finances. It knows everything about you. It follows your moves, analyzes markets, adapts to your goals and invests faster and smarter than you can. Your investments soar. But then one day, you wake up to a nightmare: Your savings have been transferred to a rogue state, and they’re gone.

    You seek remedies and justice but find none. Who’s to blame? The robot’s developer? The artificial intelligence company behind the robot’s “brain”? The bank that approved the transactions? Lawsuits fly, fingers point, and your lawyer searches for precedents, but finds none. Meanwhile, you’ve lost everything.

    This is not the doomsday scenario of human extinction that some people in the AI field have warned could arise from the technology. It is a more realistic one and, in some cases, already present. AI systems are already making life-altering decisions for many people, in areas ranging from education to hiring and law enforcement. Health insurance companies have used AI tools to determine whether to cover patients’ medical procedures. People have been arrested based on faulty matches by facial recognition algorithms.

    By bringing government and industry together to develop policy solutions, it is possible to reduce these risks and future ones. I am a former IBM executive with decades of experience in digital transformation and AI. I now focus on tech policy as a senior fellow at Harvard Kennedy School’s Mossavar-Rahmani Center for Business and Government. I also advise tech startups and invest in venture capital.

    Drawing from this experience, my team spent a year researching a way forward for AI governance. We conducted interviews with 49 tech industry leaders and members of Congress, and analyzed 150 AI-related bills introduced in the last session of Congress. We used this data to develop a model for AI governance that fosters innovation while also offering protections against harms, like a rogue AI draining your life savings.

    Striking a balance

    The increasing use of AI in all aspects of people’s lives raises a new set of questions to which history has few answers. At the same time, the urgency to address how it should be governed is growing. Policymakers appear to be paralyzed, debating whether to let innovation flourish without controls or risk slowing progress. However, I believe that the binary choice between regulation and innovation is a false one.

    Instead, it’s possible to chart a different approach that can help guide innovation in a direction that adheres to existing laws and societal norms without stifling creativity, competition and entrepreneurship.

    Bloomberg Intelligence analyst Tamlin Bason explains the regulatory landscape and the need for a balanced approach to AI governance.

    The U.S. has consistently demonstrated its ability to drive economic growth. The American tech innovation system is rooted in entrepreneurial spirit, public and private investment, an open market and legal protections for intellectual property and trade secrets. From the early days of the Industrial Revolution to the rise of the internet and modern digital technologies, the U.S. has maintained its leadership by balancing economic incentives with strategic policy interventions.

    In January 2025, President Donald Trump issued an executive order calling for the development of an AI action plan for America. My team and I have developed an AI governance model that can underpin an action plan.

    A new governance model

    Previous presidential administrations have waded into AI governance, including the Biden administration’s since-recinded executive order. There has also been an increasing number of regulations concerning AI passed at the state level. But the U.S. has mostly avoided imposing regulations on AI. This hands-off approach stems in part from a disconnect between Congress and industry, with each doubting the other’s understanding of the technologies requiring governance.

    The industry is divided into distinct camps, with smaller companies allowing tech giants to lead governance discussions. Other contributing factors include ideological resistance to regulation, geopolitical concerns and insufficient coalition-building that have marked past technology policymaking efforts. Yet, our study showed that both parties in Congress favor a uniquely American approach to governance.

    Congress agrees on extending American leadership, addressing AI’s infrastructure needs and focusing on specific uses of the technology – instead of trying to regulate the technology itself. How to do it? My team’s findings led us to develop the Dynamic Governance Model, a policy-agnostic and nonregulatory method that can be applied to different industries and uses of the technology. It starts with a legislative or executive body setting a policy goal and consists of three subsequent steps:

    1. Establish a public-private partnership in which public and private sector experts work together to identify standards for evaluating the policy goal. This approach combines industry leaders’ technical expertise and innovation focus with policymakers’ agenda of protecting the public interest through oversight and accountability. By integrating these complementary roles, governance can evolve together with technological developments.

    2. Create an ecosystem for audit and compliance mechanisms. This market-based approach builds on the standards from the previous step and executes technical audits and compliance reviews. Setting voluntary standards and measuring against them is good, but it can fall short without real oversight. Private sector auditing firms can provide oversight so long as those auditors meet fixed ethical and professional standards.

    3. Set up accountability and liability for AI systems. This step outlines the responsibilities that a company must bear if its products harm people or fail to meet standards. Effective enforcement requires coordinated efforts across institutions. Congress can establish legislative foundations, including liability criteria and sector-specific regulations. It can also create mechanisms for ongoing oversight or rely on existing government agencies for enforcement. Courts will interpret statutes and resolve conflicts, setting precedents. Judicial rulings will clarify ambiguous areas and contribute to a sturdier framework.

    Benefits of balance

    I believe that this approach offers a balanced path forward, fostering public trust while allowing innovation to thrive. In contrast to conventional regulatory methods that impose blanket restrictions on industry, like the one adopted by the European Union, our model:

    • is incremental, integrating learning at each step.
    • draws on the existing approaches used in the U.S. for driving public policy, such as competition law, existing regulations and civil litigation.
    • can contribute to the development of new laws without imposing excessive burdens on companies.
    • draws on past voluntary commitments and industry standards, and encourages trust between the public and private sectors.

    The U.S. has long led the world in technological growth and innovation. Pursuing a public-private partnership approach to AI governance should enable policymakers and industry leaders to advance their goals while balancing innovation with transparency and responsibility. We believe that our governance model is aligned with the Trump administration’s goal of removing barriers for industry but also supports the public’s desire for guardrails.

    Carvão advises tech startups and invests in venture capital.

    – ref. Beyond AI regulation: How government and industry can team up to make the technology safer without hindering innovation – https://theconversation.com/beyond-ai-regulation-how-government-and-industry-can-team-up-to-make-the-technology-safer-without-hindering-innovation-251010

    MIL OSI – Global Reports –

    March 8, 2025
  • MIL-OSI Russia: PhysMech and SPbPU PISh “Digital Engineering” presented research at the Winter School on Continuous Media Mechanics

    Translartion. Region: Russians Fedetion –

    Source: Peter the Great St Petersburg Polytechnic University – Peter the Great St Petersburg Polytechnic University –

    Representatives of the Institute of Physics and Mechanics of Peter the Great St. Petersburg Polytechnic University (SPbPU) and the Advanced Engineering School “Digital Engineering” (AES) took part inXXIV Winter School on Continuous Media Mechanics in Perm. The event was held within the framework of the Program for the creation and development of a world-class scientific center “Supersonic” for 2020-2024 with the support of the Ministry of Science and Higher Education of the Russian Federation.

    The event was organized by the Institute of Continuous Media Mechanics of the Ural Branch of the Russian Academy of Sciences – a branch of the Perm Federal Research Center of the Ural Branch of the Russian Academy of Sciences.

    The Winter School on Continuous Media Mechanics is held to build a systematic discussion on current issues in this field and is aimed at developing research activities, including among young specialists. The event included a competition of reports among students, postgraduates and young scientists.

    The XXIV Winter School on Continuous Media Mechanics was attended by 320 people from 21 cities of Russia, including St. Petersburg, Moscow, Yekaterinburg, Novosibirsk, Izhevsk, Kazan, Samara and others. The event featured 319 reports in eight sections, the abstracts of which were included in the collection of papers on the results of the school.

    The main topics of the event program:

    computational continuum mechanics, physics and mechanics of meso- and nanostructured systems, mechanics of functional materials, convection, hydrodynamic stability and turbulence, hydrodynamics of non-Newtonian fluids and fluids with special properties, fundamental and applied magnetohydrodynamics, continuum mechanics in biology and medicine, mining mechanics, monitoring of natural and man-made systems.

    Scientists, postgraduates, and students of the Institute of Physics and Mechanics of SPbPU presented the results of research and development by research teams on current issues in computational continuum mechanics, mechanics of functional materials, hydrodynamic stability, physics and mechanics of meso- and nanostructured systems, chemomechanics, fundamental and applied hydrodynamics, and gas dynamics. The research results contribute to the development of engineering applications of microelectronics, hydrogen technologies, modern electronic and optoelectronic devices, boiler equipment, methods for testing thermal conductivity at the nanoscale, and calculations of fracture mechanics parameters.

    Plenary reports:

    Krivtsov Anton-Irzhi Miroslavovich, Director of the Higher School of Theoretical Mechanics and Mathematical Physics of the Physics and Mechanical Institute of SPbPU, Head of the Laboratory of Modeling of Production Technologies and Processes of the PISh SPbPU, Corresponding Member of the Russian Academy of Sciences, Associate Professor, Doctor of Physical and Mathematical Sciences. Topic of the report: “Using Approaches Based on the Bernoulli-Euler and Schrödinger Gas Dynamics Kinetics Equations to Describing Transport Processes”; Freidin Alexander Borisovich, Senior Researcher, Professor of the Higher School of Mechanics and Control Processes of the Physics and Mechanical Institute of SPbPU, Doctor of Physical and Mathematical Sciences. Topic of the report: “Related Problems of Chemomechanics: Statements and Solutions”.

    Sectional reports:

    Belyaev Aleksandr Konstantinovich, Director of the Higher School of Mechanics and Control Processes of the Institute of Physics and Mechanics of SPbPU, Corresponding Member of the Russian Academy of Sciences, Associate Professor, Doctor of Physical and Mathematical Sciences. Topic of the report: “Models of Hydrogen Motion in an Extruder at Low Temperatures”; Kovalev Igor Alekseevich, student of the Institute of Physics and Mechanics of SPbPU. Topic of the report: “Dislocation Relaxation of Stresses in a Cylindrical Quantum Ring Near the Free Surface”; Kuzkin Vitaly Andreevich, Professor of the Higher School of Theoretical Mechanics and Mathematical Physics of the Institute of Physics and Mechanics of SPbPU, Doctor of Physical and Mathematical Sciences. Topic of the report: “Ballistic Thermoelasticity of Nonlinear Chains”; Savikovsky Artem Viktorovich, postgraduate student of the Institute of Physics and Mechanics of SPbPU. Topic of the report: “Calculation of Stress Intensity Factors through Jk-Integrals for Anisotropic Materials”; Sedova Yulia Sergeevna, postgraduate student of the Physics and Mechanical Institute of SPbPU. Topic of the report: “Analysis of the results of testing ring samples of boiler tubes using mechanical models of hydrogen embrittlement”; Ivanova Alexandra Borisovna, postgraduate student of the Physics and Mechanical Institute of SPbPU. Topic of the report: “Related problems of chemomechanics for an elastic and viscoelastic reaction product”.

    The winners of the competition of reports among students, postgraduates and young scientists were awarded diplomas for the presentations of student Igor Kovalev, postgraduates Artem Savikovsky, Alexandra Ivanova and Yulia Sedova, as well as professor of the Higher School of Theoretical Mechanics and Mathematical Physics of the Physical-Mechanical Institute of SPbPU Vitaly Kuzkin.

    The laureates were awarded at a meeting of the Academic Council of the Physics and Mechanics Institute of SPbPU. Acting Director of the Physics and Mechanics Institute of SPbPU Nikolay Ivanov congratulated the winners and presented them with diplomas.

    The council members highly appreciated the contribution of young scientists to the development of their research areas.

    It is gratifying that such a representative delegation from the Polytechnic University participated in the Perm Winter School. Young scientists and venerable professors confirmed the high level of the St. Petersburg school of mechanics. We wish everyone further success, and especially students who are just starting their path in science, – noted Nikolay Georgievich.

    The team of the Advanced Engineering School of SPbPU “Digital Engineering” demonstrated research in the field of continuum mechanics, implemented using systems digital engineering technologies for the tasks of medicine, healthcare, construction, automotive and aircraft manufacturing.

    Sectional reports:

    Antonova Olga Vladimirovna, Associate Professor of the Higher School of Advanced Digital Technologies of the Advanced Engineering School of SPbPU “Digital Engineering”, Candidate of Technical Sciences. Topic: “Application of hyperelastic material models to describe the mechanical behavior of high-tech medical devices and biological tissues”; Sadovchenko Ekaterina Alekseevna, Master’s student of the Primorsky Polytechnical School of SPbPU, engineer in the Applied Research and Development direction of the Engineering Center (CompMechLab®) of Primorsky Polytechnical School of SPbPU. Topic: “Modeling the process of installing dental implants using finite element analysis”; Nezhinskaya Liliya Sergeevna, Master’s student of the Primorsky Polytechnical School of SPbPU, engineer in the Applied Research and Development direction of the Engineering Center (CompMechLab®) of Primorsky Polytechnical School of SPbPU. Topic: “Study of elastic-plastic properties of meta-biomaterials. Full-scale and virtual tests” in the section “Physics and mechanics of meso- and nanostructured systems”; Ivanov Maxim Vyacheslavovich, engineer of the Department of development of cars and equipment of the Engineering Center (CompMechLab®) of PISh SPbPU, assistant of the Higher School of Advanced Digital Technologies, graduate of the Advanced Engineering School of SPbPU “Digital Engineering”. Topic: “Optimization of the bearing capacity of metal panels with a tetrahedral filler”.

    In the course of Olga Antonova’s research, an analysis was conducted of the features of the application of hyperelastic models of materials to describe the behavior of various medical devices and biological tissues used in modern medical practice, primarily in the field of cardiology.

    In the future, the obtained results can be used as a basis for modeling the processes of installing coronary and endobiliary stents, prosthetic rings for annuloplasty, optimizing the methods of these medical interventions, as well as in developing recommendations for medical workers, concluded Olga Vladimirovna.

    Ekaterina Sadovchenko spoke about the methodology for modeling the process of installing dental implants in bone blocks of different densities using the finite element method.

    The research presented by Liliya Nezhinskaya within the framework of the XXIV Winter School on Continuous Media Mechanics will allow the formation of mathematical models of meta-biomaterials of various topologies for their further application in the development of products in the field of tissue engineering for the treatment of bone defects.

    It should be noted that the project represents a part research, supported by the Russian Science Foundation, which is carried out by a research group led by the Vice-Rector for Digital Transformation of SPbPU, Head of the SPbPU Digital Engineering School Alexey Borovkov.

    Maxim Ivanov spoke about a project to optimize the load-bearing capacity of metal panels with a tetrahedral filler, which is part of his PhD thesis. Layered panels with such a filler are actively used in construction, the automotive industry, and aircraft manufacturing. The results obtained can be used to optimize the technological process of manufacturing a filler of complex shape.

    The presentations of Liliya Nezhinskaya and Ekaterina Sadovchenko were also noted at the competition of reports among students, postgraduates and young scientists. The winners received diplomas.

    The research of the participants of the XXIV Winter School on Continuous Media Mechanics was highly appreciated by the scientific committee, which noted their relevance and practical focus while maintaining the fundamental nature of the approaches used.

    Please note: This information is raw content directly from the source of the information. It is exactly what the source states and does not reflect the position of MIL-OSI or its clients.

    MIL OSI Russia News –

    March 8, 2025
  • MIL-OSI Asia-Pac: Hong Kong and Macao cohost investment promotion seminar to encourage Macao enterprises to expand overseas via Hong Kong (with photos)

    Source: Hong Kong Government special administrative region

    Hong Kong and Macao cohost investment promotion seminar to encourage Macao enterprises to expand overseas via Hong Kong (with photos)
    ******************************************************************************************

    The Chief Executive, Mr John Lee, met with the Chief Executive of the Macao Special Administrative Region, Mr Sam Hou-fai, at Government House last month to exchange views on further promoting Hong Kong’s co-operation with Macao and the high-quality development of the Guangdong-Hong Kong-Macao Greater Bay Area (GBA). To implement and enhance co-operation between the two places, Invest Hong Kong (InvestHK) cohosted an investment promotion seminar with the Commerce and Investment Promotion Institute of the Macao Special Administrative Region in Macao yesterday (March 6), receiving about 90 local representatives from various sectors, including manufacturing, branding, retail, food and beverage (F&B), import and export trading, as well as chambers and associations. The seminar aimed to update Macao enterprises on Hong Kong’s latest business environment and new opportunities, especially in retail, F&B and trade sectors, encouraging them to leverage Hong Kong’s unique advantages to expand overseas.     Entitled Macao Enterprises Expansion Series – Hong Kong’s New Business Opportunities Seminar (Retail, F&B and Trade), the seminar marked the first collaboration between the two promotion agencies in 2025, aiming to enhance learning from each other and strengthen co-operation between the two cities, as well as to explore new business opportunities in the GBA.     “Hong Kong and Macao share a strong bond as dynamic and complementary economies within the GBA,” said Associate Director-General of Investment Promotion at InvestHK Mr Arnold Lau. “Macao goods have long been a favourite among Hong Kong consumers, showcasing the strong cultural and economic ties between the two vibrant cities. By expanding into Hong Kong, Macao enterprises can extend their reach not only to the local market, but also promote their products to the international and Mainland visitors passing through Hong Kong. Moreover, Hong Kong has many trade shows that attract international buyers. The city is an ideal platform for Macao enterprises to connect to the world and expand globally,” he explained.     At the seminar, the President of the Commerce and Investment Promotion Institute of the Macao Special Administrative Region, Mr Vincent U, said, “Hong Kong and Macao have maintained close business co-operation and commercial ties for many years, including holding joint investment promotion activities to promote opportunities in the GBA. Building on this long-standing collaboration, we aim to further strengthen two-way investment co-operation and explore more opportunities for Hong Kong-Macao collaborations and the development of the GBA market.”     The Head of Consumer Products of InvestHK, Ms Angelica Leung, and the Head of Tourism and Hospitality of InvestHK, Ms Sindy Wong, highlighted the latest industry trends and shared case studies respectively with Macao enterprises during the seminar, helping them to gain a better understanding of Hong Kong’s market and advantages. They also provided information on the latest government policies, including details on industry events and available funding support to help businesses expand, enhance competitiveness through digital transformation and explore international markets. Macao enterprises that have a presence in Hong Kong also shared their practical insights at the event, encouraging local enterprises to raise brand awareness and “go global” via Hong Kong.     InvestHK will continue to collaborate with related Macao organisations to jointly promote business opportunities in Hong Kong, assisting local enterprises to expand overseas via the city.

    Ends/Friday, March 7, 2025Issued at HKT 10:00

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    MIL OSI Asia Pacific News –

    March 8, 2025
  • MIL-OSI Asia-Pac: Medicine shop salesman convicted of engaging in commercial practice involving misleading omission for selling Chinese herbal medicine

    Source: Hong Kong Government special administrative region

    Medicine shop salesman convicted of engaging in commercial practice involving misleading omission for selling Chinese herbal medicine
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    A medicine shop salesman was earlier convicted of engaging in a commercial practice involving a misleading omission in the sale of a Chinese herbal medicine, in contravention of the Trade Descriptions Ordinance (TDO), at the West Kowloon Magistrates’ Courts on February 21. After being remanded in custody for 14 days, the salesman was sentenced to 120 hours’ community service order today (March 7) and must compensate the victim in the case by an amount of $11,000.     Customs earlier received information from a Mainland visitor alleging that a staff member of a medicine shop in Mong Kok misled him in the course of selling a Chinese herbal medicine. After an investigation, it was revealed that the staff member did not disclose the pricing unit of the medicine despite the visitor’s inquiry, misleading the visitor to believe that the unit price of the medicine was calculated per catty. After the medicine was ground into powder, the staff member revealed that it was priced per mace and cost $22,400 in total, which was 160 times higher than what was expected. Eventually the visitor was forced to purchase a portion of the medicine at around half the price.     Customs has long been concerned about visitors being misled into making purchases by unfair trade practices and has established a Quick Response Team to handle urgent complaints lodged by short-haul visitors. The complaints will be promptly referred to investigators to handle with priority.     Customs reminds traders to comply with the requirements of the TDO. Consumers should procure products from reputable traders. They are also reminded to check carefully the total price and unit price of the goods before making a payment, and to retain the transaction receipts and related records, which can be used as the basis for follow-up action in case a complaint is lodged in the future.       Under the TDO, any trader who engages in a commercial practice that omits or hides material information or provides material information in a manner that is unclear, unintelligible, ambiguous or untimely, and as a result causes, or is likely to cause, an average consumer to make a transactional decision, commits an offence of misleading omissions. The maximum penalty upon conviction is a fine of $500,000 and imprisonment for five years.     ???     Members of the public may report any suspected violation of the TDO to Customs’ 24-hour hotline 182 8080 or its dedicated crime-reporting email account (crimereport@customs.gov.hk) or online form (eform.cefs.gov.hk/form/ced002).

    Ends/Friday, March 7, 2025Issued at HKT 15:08

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    MIL OSI Asia Pacific News –

    March 8, 2025
  • MIL-OSI Asia-Pac: Prime Minister Shri Narendra Modi inaugurates and launches various development works worth over Rs 2580 crore in Silvassa,Union Territory of Dadra and Nagar Haveli and Daman and Diu

    Source: Government of India (2)

    Prime Minister Shri Narendra Modi inaugurates and launches various development works worth over Rs 2580 crore in Silvassa,Union Territory of Dadra and Nagar Haveli and Daman and Diu

    Dadra and Nagar Haveli, Daman and Diu, are our pride, our heritage: PM

    Dadra and Nagar Haveli, Daman and Diu have reached a saturation level in several schemes: PM

    Jan Aushadhi means guarantee of affordable treatment! The mantra of Jan Aushadhi is – lower prices, effective medicines: PM

    We all should reduce 10% of the cooking oil in our food,manage with 10% less oil every month,This will be a significant step towards reducing obesity: PM

    Posted On: 07 MAR 2025 5:59PM by PIB Delhi

    The Prime Minister Shri Narendra Modi launched various development works worth over ₹2580 crore in Silvassa, Union Territory of Dadra and Nagar Haveli and Daman and Diu today. He also inaugurated the Namo Hospital in Silvassa earlier to the event. Addressing the gathering, the Prime Minister expressed his gratitude towards the dedicated workers of the Union Territory of Dadra and Nagar Haveli, Daman and Diu for giving him the opportunity to connect and engage with the region. He acknowledged the warmth and the long-standing connection he has had with the people, sharing that his bond with the region is decades old. He highlighted the progress the region has made since his government came to power in 2014, transforming the potential of Dadra and Nagar Haveli, Daman and Diu into a modern and progressive identity.

    “The natural beauty of Silvassa and the love of its people, as well as Dadra and Nagar Haveli, Daman and Diu, you all know how long my connection with you has been. This decades-old bond, the joy I feel when I come here, only you and I understand it”, Shri Modi added. The Prime Minister mentioned that when he first visited, the area was vastly different, with people questioning what could come of a small coastal region. However, he always had faith in the people of this place and their capabilities. The Prime Minister pointed out that under the leadership of his government, this faith has been transformed into progress, turning Silvassa into a cosmopolitan city, thriving with new opportunities for all its residents.

    Shri Modi also shared an example of Singapore, which, in its early days, was a small fishing village. He emphasized that the transformation of Singapore happened due to the strong willpower of its people.  The Prime Minister encouraged the citizens of the Union Territory to adopt a similar resolve for development, assuring them that he would stand by them, but they too must take the initiative to move forward.

    “Dadra and Nagar Haveli, Daman and Diu is not just a Union Territory but a source of pride and heritage. This is why we are transforming the region into a model state known for its holistic development”,  Shri Modi emphasized. The Prime Minister stated how he envisions the region to be recognized for its high-tech infrastructure, modern healthcare services, world-class educational institutes, tourism, blue economy, industrial progress, new opportunities for youth, and women’s participation in development.

    Shri Modi noted that under the leadership of Shri Praful Patel and with the support of the central government, the region is fast progressing towards these goals. Over the last 10 years, significant progress has been made in development. The region is now emerging on the national map with a distinct identity in terms of development. Various government schemes, such as One Nation One Ration Card, Jal Jeevan Mission, BharatNet, PM Jan Dhan Yojana, PM Jeevan Jyoti Bima, and PM Suraksha Bima, have brought substantial benefits to the people, especially the underprivileged and tribal communities.

    The Prime Minister announced that the next goal is to achieve 100% saturation in initiatives like Smart Cities Mission, Samagra Shiksha, and PM Mudra Yojana. He highlighted that for the first time, the government is reaching out directly to people with these welfare schemes, ensuring that every citizen benefits from the government’s plans.

    The Prime Minister  highlighted the transformation of Dadra and Nagar Haveli, Daman and Diu in infrastructure, education, employment, and industrial development. He pointed out that earlier, youth from the region had to go outside for higher education, but today, the region is home to six national-level institutes. These include Namo Medical College, Gujarat National Law University, IIIT Diu, National Institute of Fashion Technology, Institute of Hotel Management and Catering Technology, and the Daman Engineering College. These institutions have made Silvassa and the region a new education hub. “To further benefit the youth, seats have been reserved for them in these institutes. Earlier, I was happy to see that this is a region where education is provided  in four different mediums: Hindi, English, Gujarati, and Marathi. Now, I am also proud to say that children in primary and junior schools here are studying in smart classrooms”, Shri Modi added.

    Shri Modi said that in recent years, modern healthcare services have expanded significantly in the region. “In 2023, I  had the opportunity to inaugurate Namo Medical College here. Along with this, a new hospital with a capacity of 450 beds has been added, which was also inaugurated today. The healthcare facilities in Silvassa will greatly benefit the tribal community in the region”, Shri Modi underscored. 

    The Prime Minister  highlighted the significance of today’s healthcare projects, as it coincides with Jan Aushadhi Diwas. He emphasized that Jan Aushadhi ensures affordable treatment. Under this initiative, the government is providing quality hospitals, free treatment under Ayushman Bharat, and affordable medicines through Jan Aushadhi centers. More than 15,000 Jan Aushadhi centers across the country offer medicines at up to 80% lower prices. Around 40 Jan Aushadhi centers are benefiting the people of Dadra and Nagar Haveli, Daman and Diu. The government aims to open 25,000 Jan Aushadhi centers nationwide in the future. “Since the launch of this initiative, nearly ₹6,500 crore worth of affordable medicines have been provided to the needy, saving over ₹30,000 crore for the poor and middle class. This initiative has made the treatment of several critical diseases more affordable, demonstrating the government’s sensitivity to the needs of ordinary citizens”, Shri Modi emphasised.

    The Prime Minister addressed the rising concern of lifestyle diseases, particularly obesity, which has become a major health threat. He referred to a recent report predicting that by 2050, over 440 million Indians will suffer from obesity. “This alarming figure indicates that one in every three people could face serious health issues due to obesity, potentially making it a life-threatening condition”, Shri Modi stated.

    To combat this, the Prime Minister urged everyone to take proactive steps to reduce obesity. He emphasized the importance of reducing the consumption of cooking oil by 10% each month, asking people to commit to using 10% less oil in their daily cooking. He also encouraged the inclusion of regular physical activity, like walking a few kilometers daily, to maintain a healthy lifestyle and prevent obesity. “India is committed to achieving the vision of a developed nation. Only a healthy nation can achieve such a goal”, Shri Modi emphasised.

    Shri Modi highlighted the rapid industrial growth in Dadra and Nagar Haveli, Daman and Diu over the past decade. With the launch of the Mission Manufacturing initiative in the recent budget, the region is poised to benefit significantly. Hundreds of new industries have started, and several existing industries have expanded, attracting thousands of crores in investment. These industries are providing large-scale employment opportunities, especially for the tribal community, women, and marginalized groups. “The Gir Adarsh Jeevika Yojana has been implemented to empower SC, ST, OBC, and women, while new self-employment opportunities have been created with the establishment of small dairy farms”, Shri Modi added.

    The Prime Minister underscored that tourism has also emerged as a major source of employment. The region’s beaches and rich heritage are attracting tourists from both India and abroad. Developments like the Ram Setu, Namo Path, Tent City in Daman, and the popular Night Market are enhancing the region’s appeal. Shri Modi stated that a large bird sanctuary has been established, and plans for an eco-resort in Dudhani are underway. Coastal promenade and beach development work is being carried out in Diu. “The Diu Beach Games in 2024 boosted interest in beach sports, and the Blue Flag certification has made the Ghoghla Beach in Diu a popular tourist destination. Additionally, a cable car project is being developed in Diu, offering spectacular views of the Arabian Sea, making the region one of India’s top tourist destinations”, Shri Modi added.

    Highlighting the significant connectivity improvements in Dadra and Nagar Haveli, Daman and Diu, Prime Minister Shri Narendra Modi  said that a bullet train station is being built near Dadra, and the Mumbai-Delhi Expressway passes through Silvassa. Over the past few years, several kilometers of new roads have been constructed, with over 500 kilometers of road work currently underway, involving investments worth thousands of crores. “The region is also benefiting from the UDAN scheme, and the local airport is being upgraded to enhance connectivity. The government is committed to ensuring comprehensive development and improving infrastructure in the region”, Shri Modi added.

    The Prime Minister  expressed his happiness that Dadra and Nagar Haveli, Daman and Diu are becoming models of development, good governance, and ease of living. He pointed out that in the past, people had to visit government offices repeatedly to resolve their issues, but now most government-related tasks can be completed with just one click on their mobile phones. This new approach has greatly benefited the tribal areas that were neglected for decades. Special camps are being organized in villages to listen to people’s problems and resolve them on the spot. The Prime Minister congratulated Shri Praful Patel and his team for these efforts and assured the people that the government will continue working towards the development of the region.“I congratulate the people of Dadra and Nagar Haveli, Daman and Diu for the successful development projects launched today. I express my heartfelt gratitude for the warm welcome, affection, and respect shown by the citizens of the Union Territory”, the Prime Minister concluded.

    Background

    Boosting healthcare facilities in all corners of the country has been a primary focus of the Prime Minister. In line with this, he inaugurated NAMO Hospital (Phase I) in Silvassa. This 450 bedded hospital, built at the cost of over Rs 460 crore, will significantly strengthen healthcare services in the Union Territory. It will provide state-of-the-art medical care to the people in the region, especially the tribal communities.

    The Prime Minister also inaugurated and  laid the foundation stone of multiple development projects for the UT worth over Rs 2580 crore at Silvassa. These include various village roads and other road infrastructure, schools, health and wellness centres, Panchayat and administrative buildings, Anganwadi centres, water supply and sewage infrastructure among others. These projects aim to improve connectivity, promote industrial growth, encourage tourism, create employment opportunities and aim at enhancing public welfare initiatives in the region.

    Gir Adarsh Aajeevika Yojana aims to boost economic empowerment of women belonging to scheduled castes (SCs), scheduled tribes (STs), other backward classes (OBCs), minorities and divyangjan in the region through setting up small dairy farms and bringing social and economic changes in their lives. The Sylvan Didi scheme is an initiative to uplift women street vendors by providing them with aesthetically designed carts, with co funding from PM SVANIDHI scheme.

     

    दादरा और नगर हवेली, दमण और दीव… ये प्रदेश हमारा गर्व है… हमारी विरासत है। pic.twitter.com/CN1ZjijEOH

    — PMO India (@PMOIndia) March 7, 2025

    दादरा और नगर हवेली, दमण और दीव… ये कई योजनाओं में सैचुरेशन की स्थिति में पहुंच गए हैं: PM @narendramodi pic.twitter.com/xRjJqsmScw

    — PMO India (@PMOIndia) March 7, 2025

    जनऔषधि यानी- सस्ते इलाज की गारंटी!

    जनऔषधि का मंत्र है- दाम कम, दवाई में दम! pic.twitter.com/4GscUrLDb9

    — PMO India (@PMOIndia) March 7, 2025

    हम सभी को अपने खाने के तेल में 10% की कटौती करनी चाहिए।

    हमें हर महीने 10% कम तेल में काम चलाने का प्रयास करना है।

    मोटापा कम करने की दिशा में ये एक बहुत बड़ा कदम होगा: PM @narendramodi pic.twitter.com/61lgZ4XAFc

    — PMO India (@PMOIndia) March 7, 2025

    A landmark day for Dadra and Nagar Haveli and Daman and Diu as key development projects are being launched. Speaking at a programme in Silvassa. https://t.co/re1Am2n62t

    — Narendra Modi (@narendramodi) March 7, 2025

     

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    (Release ID: 2109163) Visitor Counter : 78

    MIL OSI Asia Pacific News –

    March 8, 2025
  • MIL-OSI Asia-Pac: Cluster of Human Metapneumovirus in United Christian Hospital

    Source: Hong Kong Government special administrative region

    Cluster of Human Metapneumovirus in United Christian Hospital
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    The following is issued on behalf of the Hospital Authority:     The spokesperson for United Christian Hospital made the following announcement today (March 7):     Mild respiratory symptoms appeared in patients in a female psychiatric ward starting on February 25. Appropriate tests had been arranged for the patients, among which three patients (aged 61 to 70) tested positive for Human Metapneumovirus and met the case definition. Patients are being treated in isolation and are in stable condition.     A full investigation and thorough cleaning and disinfection have been conducted in the ward. Stringent droplet and contact precautions and enhancement of hand hygiene will be carried out.     The hospital will continue to closely monitor the conditions of the patients in the ward. The cases have been reported to the Hospital Authority Head Office and the Centre for Health Protection for necessary follow-up.

    Ends/Friday, March 7, 2025Issued at HKT 18:30

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    MIL OSI Asia Pacific News –

    March 8, 2025
  • MIL-OSI Europe: NRRP steering committee meeting held to verify progress of local healthcare measures

    Source: Government of Italy (English)

    A steering committee meeting for the National Recovery and Resilience Plan (NRRP) was held at Palazzo Chigi today, focusing solely on the Plan’s Health Mission. The purpose of the meeting, chaired by the Minister for European Affairs, the NRRP and Cohesion Policy, Tommaso Foti, and attended by the Minister of Health, Orazio Schillaci, as well as regional presidents and representatives from the Conference of Regions and Autonomous Provinces, was to review in detail the progress of measures at local level. The healthcare-focused steering committee forms part of the enhanced monitoring of NRRP-funded investments, which see regions playing an active role in their implementation, launched by the Government ahead of negotiations with the European Commission regarding possible adjustments aimed at fully implementing the Plan.

    In order to achieve the objectives required for the ninth and tenth (and final) instalment of the NRRP, the meeting reviewed implementation of strategic projects, such as: community homes and hospitals; major healthcare equipment; building renovation work and safety upgrades to ensure safe hospitals; and, digitalisation of I and II level emergency departments (‘DEA’). These measures are of significant importance to strengthen Italy’s entire national health system and improve citizens’ quality of life.

    The meeting focused on the strategic investments included in the Plan’s Health Mission aimed at enhancing primary care, speeding up service delivery and improving healthcare at local level, with regional authorities, as implementing bodies, having the delicate task of finalising, testing and activating all the planned measures, in accordance with the Plan’s conditions.

    In order to help regional authorities verify schedules and achieve the planned objectives, a certification has been created to certify implementation status and the achievement of the Plan’s milestones and targets. This thorough review process by the Government will allow regional authorities to indicate any areas requiring attention in relation to the specific implementation of their measures, and to propose possible solutions and targeted actions to achieve the objectives provided for.

    The NRRP task force within the Presidency of the Council of Ministers, working in conjunction with the Ministry of Health, ensures the utmost cooperation with the authorities in charge of implementing measures, providing appropriate support for the preparation of the certifications. Without prejudice to the milestones and targets to be achieved for the ninth and tenth instalments, official 2024 figures confirm the launch of 480 ‘local operational centres’ (‘Centrali Operative Territoriali’, ‘COT’), the first community homes and hospitals opened throughout Italy and approximately 2,500 pieces of major healthcare equipment, which will play a crucial role in reducing regional divides and in making the services provided by the national health system more efficient.

    MIL OSI Europe News –

    March 8, 2025
  • MIL-OSI Russia: In Novosibirsk, the results of the school track of the National Technology Olympiad in the profile “Genome Editing” were summed up

    Translartion. Region: Russians Fedetion –

    Source: Novosibirsk State University – Novosibirsk State University –

    The final stage of the National Technology Olympiad (NTO) in the profile “Genomic Editing” has ended in Novosibirsk. 51 schoolchildren from 18 regions of Russia aged 14 to 17 took part in the final stage. The organizers of the profile “Genomic Editing” are Novosibirsk State University, SUNC NSU, Advanced Engineering School of NSU and the Institute of Chemical Biology and Fundamental Medicine of the Siberian Branch of the Russian Academy of Sciences. The partner of the profile is the regional center “Altair”.

    The final stage of the profile “Genome Editing” was invented at Novosibirsk State University and has been held here for the seventh year. The finalists of the Olympiad used technologies for managing the properties of biological objects to edit the properties of green fluorescent protein. All stages of the Olympiad took place in the premises of the leisure and educational centers of the NSU SUNC, which are among the first-priority facilities modern campus of NGThey were built within the framework of the national project “Youth and Children.

    During the week, schoolchildren solved Olympiad problems proposed by researchers from Novosibirsk State University, the Institute of Chemical Biology and Fundamental Medicine of the Siberian Branch of the Russian Academy of Sciences. All final tasks were practice-oriented and aimed at implementing the country’s scientific and technical development strategy.

    — Holding the National Technology Olympiad in the field of “Genome Editing” in Novosibirsk is a logical choice. It is here, in the heart of Siberian science, that one of the strongest genetic schools in the country was formed. Akademgorodok, institutes of the Siberian Branch of the Russian Academy of Sciences, such as the Institute of Chemical Biology and Fundamental Medicine, the Institute of Cytology and Genetics of the Siberian Branch of the Russian Academy of Sciences, have been setting the tone in molecular biology and genetics research for decades. This is a unique environment where schoolchildren can already immerse themselves in the atmosphere of advanced science, work with leading scientists and adopt their experience. The finalists have proven that they are capable of solving problems at the level of current scientific trends. Such projects not only strengthen the continuity of generations in science, but also emphasize the role of Novosibirsk as a center of attraction for young talents ready to change the future of bioengineering and medicine. I am sure that these guys will continue the traditions of the Siberian scientific school, and their ideas will become the basis for breakthrough discoveries in Russia. The Novosibirsk Region Government will continue to build a system of support for gifted children and stimulate their early involvement in science, including through specialized classes with in-depth study of disciplines and the Altair regional center, commented Vadim Vasiliev, Minister of Science and Innovation Policy of the Novosibirsk Region.

    Sergey Sedykh, PhD in Biology and head of the master’s program “Advanced Engineering Solutions for Biotechnology and Medicine” at the NSU PIS, noted the high level of training of schoolchildren from the Novosibirsk Region, who won prizes in both the team and individual championships at the Olympiad.

    The head of the project office of the National Technology Olympiad, Dmitry Kutsenko, gave a welcoming speech at the closing of the final.

    — Dear participants, I am glad that you dared to take part in our event. You applied and reached the final. I want you to take the maximum from this Olympiad, regardless of what place you will have in the end. I think that we will be glad to see you next year on the school and student tracks. I would like to separately note the leadership of the Novosibirsk Region in the number of applications — the gap was more than ten thousand people from another region. It seems that this is the result of the fruitful work of the organizers and the university management, — Dmitry Kutsenko emphasized.

    Rector of Novosibirsk State University Mikhail Fedoruk also addressed the finalists:

    — I sincerely congratulate the winners, those guys who received an invitation to the summer school of the NSU SUNC. But I think that you are all winners, because you had a few days to come into contact with the most wonderful place on Earth. Of course, we are waiting for you here again, waiting as schoolchildren, students, research workers. Therefore, I sincerely congratulate you on this wonderful event. The most important thing is that you found friends, perhaps for life. And I think that the memory of the Olympics will remain with you for the rest of your lives.

    The organizers note that the results shown by the schoolchildren demonstrate the importance of the NTO Olympiad in developing the scientific and technical potential of the younger generation and the need to support students who are interested in modern technologies.

    According to the terms of the NTO Olympiad, victory gives applicants a 100-point discount on the Unified State Exam when entering the country’s leading engineering universities.

    Results of the track “Genome editing” NTO

    10-11 grades

    Winners:

    Maria Kuznetsova, Krasnoyarsk region

    Timofey Nikonov, Irkutsk region

    Prize winners:

    Polina Kotovshchikova, Primorsky Krai

    Victoria Krivich, Omsk region

    Maria Polovnikova, Novosibirsk region

    Ekaterina Chernukhina, Moscow

    Anastasia Sidorkina, Perm region

    Roman Kobzar, St. Petersburg

    Winning Team: Le Gen da

    Polina Kotovshchikova, Primorsky Krai

    Maria Polovnikova, Novosibirsk region

    Ekaterina Chernukhina, Moscow

    8-9 grades

    Winner:

    Yulia Chechenina, Novosibirsk region

    Prize winners:

    Matvey Dubovsky, Novosibirsk region

    Alexandra Parshikova, Novosibirsk region

    Marina Lazareva, Leningrad region

    Winning Team: Molecular Machines

    Yulia Chechenina, Novosibirsk region

    Matvey Dubovsky, Novosibirsk region

    Alexandra Parshikova, Novosibirsk region

    Please note: This information is raw content directly from the source of the information. It is exactly what the source states and does not reflect the position of MIL-OSI or its clients.

    MIL OSI Russia News –

    March 8, 2025
  • MIL-OSI Asia-Pac: CSIR-NIScPR, India and CNRS, France Organised Indo-French Seminar on Open Science

    Source: Government of India (2)

    Posted On: 07 MAR 2025 5:20PM by PIB Delhi

    The CSIR-National Institute of Science Communication and Policy Research, New Delhi (CSIR-NIScPR), in collaboration with the CNRS- Department for Open Research Data, Open Science, Publications, Research Data and High Performance Computing, Paris (CNRS-DDOR), organized a two-day Indo-French Seminar on “Open Horizons: Integrating Open Access, Open Data, and Computational Innovation” on March 5-6, 2025 at CSIR-NIScPR, Satsang Vihar Campus, New Delhi-110067.

    Glimpses of Indo-French Seminar

    This significant seminar was organized to deliberate on how India and France are taking a stride towards open access, open data and open science; how digital technologies and Open Source platform offer great promise in implementing an information-driven approach to advance science, promote collaborations, increase transparency and utilize tools for partnerships between science and society. The seminar was attended by researchers, scientists, and policymakers from India and France; provided a unique opportunity for open access information sharing and networking opportunities.

    The inaugural session was attended by esteemed dignitaries from India and France with Dr. Antoine Petit, Chairman and CEO, CNRS, France; Prof. Ranjana Aggarwal, Director, CSIR-NIScPR; Prof. Nitin Seth, Director, CEFIPRA; Dr. Srinivasa Reddy, Director, CSIR-IICTon the dais.

    “We are delighted to organize this event with CNRS, France, to promote open science and research data sharing,” said Prof. Ranjana Aggarwal, Director, CSIR-NIScPR setting the tone for the conference. Describing the relevance of the event she said, “This seminar marks an important step towards fostering international collaboration and advancing sharing of scientific research for all sections of the society.” She also mentioned “One Nation One Subscription” initiative of Indian Government and its role in providing open access to larger number of stakeholders.

    Prof. Nitin Seth, Director, Indo-French Centre for the Promotion of Advanced Research (CEFIPRA) recollected how they started with 1-2 calls annually to now with so many several dedicated partnerships in S&T between the two countries. He also shared his views about the expectations from this seminar. “Open access made scientific knowledge accessible, it brings a lot of opportunities”, Dr. Srinivasa Reddy, Director CSIR-IICT shared his thoughts in theinaugural session. He also mentioned the collaborations CEFIPRA has had with CSIR-IICT from last several years.

    From the National Centre for Scientific Research (CNRS), Dr. Antoine Petit, Chairman and CEO; Dr. Sylvie Rousset, Senior Scientist & Head, Open Research Data Department (DDOR) gave a brief of CNRS and DDOR, its objectives functions and roles they are playing in making open access of articles and data, a norm in scientific research. Dr. Kasturi Mandal, CSIR-NIScPR and Dr. Sylvie Rousset, CNRS-DDOR provided the overview of the program of two days seminar like topics of discussions, and takeaways from the sessions.

    The first session of the seminar was designed on theme “Policies for Open Access, Open science in France and in India” was, chaired by Prof. Vivek Kumar Singh, Senior Adviser, NITI Aayog, Govt. of India. Dr. Marin Dacos from the French Ministry of Higher Education and Research discussed the benefits of open science like increase in academic efficiency, reproducibility, prevention of duplication, and increasing citation. He also shared highlights of French open science policies in the country. Dr. Remya Haridasan from the PSA Office, Govt. of India, discussed flagship ‘One Nation One Subscription’ (ONOS) initiative in detail like why it was needed, the impact it has on science dissemination and the hurdles faced by the stakeholders during the implementation. The other speakers who shared their thoughts on open science and data includes Dr. Sylvie Rousset and Mr. Mukesh Pund Chief Scientist, CSIR-NIScPR.

    The second session was based on topic “Open Access: A Diversity of Routes”. The session was chaired by Prof. Anirban Chakraborti, School of Computational and Integrative Sciences (SCIS), JNU, New Delhi. Dr. Bénédicte Kuntziger, CCSD, CNRS, during his talk said, “At CCSD, we promote open access through HAL, the French national open access repository, ensuring long-term, barrier-free access to publications. Notably, 167,751 full-text documents were deposited in 2024 alone, bringing the total to over 1.4 million full-text documents available through HAL as on January 2025”, he added. Dr. Françoise Rousseau, Couperin Consortium shared the model through which they negotiate with major science publishers to advance open science. Other speakers including Dr. Subbiah Arunachalam from DST-CPR, IISc Bangalore, presented an overview of open access in India, highlighting the country’s progress in promoting open access to research and Dr. Geetha Vani Rayasam, Head, CSIR-HRDG presented a perspective on open source and drug discovery, highlighting the potential of open source approaches in accelerating drug discovery and development.

    The third session of day 1 was extension of session 2 under the theme “Open Access: A Diversity of Routes (Part II)”. Session was chaired by Dr. Laurence El Khouri from CNRS-DDO. The speakers including Dr. Lidia Borrell-Damian, Science Europe discussed the benefits of Diamond Action Plan which proposes to align and develop common resources for the entire Diamond OA ecosystem. Prof. Rajeswari Raina from Shiv Nadar University asked researchers and policy makers to think step ahead while saying it’s not about one scheme, one nation or one sector, we have to see the global aspects and thus need to set the horizons and limits of open access at global level. Dr. Raphael Tournoy from Episciences discussed the importance of Overlay Journals.

    All the sessions of day 1 concluded with Q&A, where experts answered questions from the audience and shared their insights on the future of open science. This was followed by Felicitation of the guests and speakers of the event.

    The second day of the India-France seminar on Open Science and Research Data concluded successfully, featuring insightful discussions and presentations on computational innovation, research evaluation, and open data sharing.The day’s proceedings began with a session on “R&D in Computational Innovation and Open Source Software,” chaired by Dr. Avinash Kshitij, Principal Scientist, CSIR-NIScPR. The speakers included- Prof. Roberto Di Cosmo, INRIA, who discussed the “Software Heritage initiative. Prof. P. K. Suri, Delhi Technological University, delivered a talk on “Data Standardization in Agricultural.Dr. Sridhar Gautam, ICAR-Indian Institute of Horticultural Research, spoke on “Advancing R&D with Open Source Software, Open Access, and Open Data”.Sh. G Mayli Muthu Kumaran Deputy Director General, National Informatics Center (NIC) discuss on the computational innovation and open source and elaborated on the initiative towards the R&D in computational innovation at NIC. This was followed by a session on “Reforming the Evaluation of Research,” which featured presentations from:Dr. Lidia Borrell-Damian, Science Europe, discussed “Reforming Research Assessment and CoARA Initiative”. Dr. Vinayak, Principal Scientist, CSIR-NIScPR spoke on “Some New Methods for Measuring Phases of Science.” Dr. Moumita Koley from IISc, Bengaluru, discussed on the topic “Rethinking Research Assessment: Building an Efficient and Innovative Research Ecosystem in India” and Dr. Nishy. P, CSIR-NIIST, spoke on “Open Source for Research Evaluation and Future Trends”.

    The seminar also featured a session on “Open Data Sharing,” with presentations from Ms. AlkaMisra, Deputy Director General, NIC, who discussed the “Open Data sharing initiative of Govt. of India”. Dr. Marin Dacos, French Ministry of Higher Education and Research, presented “An ecosystem for sharing and opening research data” and Dr. Naresh Kumar, Chief Scientist, CSIR-NIScPR, presented his talk on “Sharing data in Science.

    The seventh session of the seminarhaving a panel discussion on “Future for Open Science, Open Data, and Open Source,” featuring experts from various fields, including Dr. Sujit Bhattacharya; Dr. Laurence El Khouri, CNRS-DDOR; Dr. Roberto Di Cosmo, INRIA Software Heritage; Dr. Deepali Kuberkar, Tata Memorial Hospital; Dr. Kasturi Mandal, CSIR-NIScPR, New Delhi; Dr. Yogesh Dhoble, CSIR-IPU, New Delhi and Dr. Sandhiya Lakshmanan, CSIR-NIScPR.

    The Indo-French Joint Seminar concluded with the valedictory session during which Dr. Naresh Kumar, Scientists, CSIR-NIScPR delivered the welcome address and highlights of the two-days intense deliberation on the Open Science, Open Source and Open Data in the R&D in Computational Innovation. Prof. Anirban Chakraborti from JNU address the need of balanced approach in moving towards the conduct of Open Science, Dr. Laurence and Dr Avinash Kshitij summarise the two-days deliberation amongst the 6 different topics, Mr.Mukesh Pund, CSIR-NIScPR shows his gratitude towards the Indian and French speakers, scholars, delegates and the all individuals involved in different roles during his address for Vote of Thanks.

     

    About CSIR-NIScPR

    The CSIR-National Institute of Science Communication and Policy Research (NIScPR) is a premier institute in India, engaged in science communication, STI based policy studies and research.

    About CNRS

    The French National Centre for Scientific Research (CNRS) is a government-funded research organization, dedicated to advancing scientific knowledge and innovation in France and globally.

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    MIL OSI Asia Pacific News –

    March 8, 2025
  • MIL-OSI Asia-Pac: PM to visit UT of Dadra and Nagar Haveli and Daman and Diu, and Gujarat on 7th – 8th March

    Source: Government of India (2)

    PM to visit UT of Dadra and Nagar Haveli and Daman and Diu, and Gujarat on 7th – 8th March

    PM to inaugurate and lay the foundation stone of multiple development projects for the UT worth over Rs 2,580 crore at Silvassa

    PM to inaugurate NAMO Hospital (Phase I) in Silvassa

    PM to launch Surat Food Security Saturation Campaign and distribute the benefits of National Food Security Act to over 2.3 lakh beneficiaries in Surat

    On the occasion of International Women’s Day, PM to participate in Lakhpati Didi programme at Navsari

    PM to launch G-SAFAL (Gujarat scheme for Antyodaya Families for Augmenting Livelihoods) and G-MAITRI (Gujarat Mentorship and Acceleration of Individuals for Transforming Rural Income) in Navsari

    Posted On: 07 MAR 2025 7:09AM by PIB Delhi

    Prime Minister Shri Narendra Modi will visit UT of Dadra and Nagar Haveli and Daman and Diu, and Gujarat on 7th – 8th March. He will travel to Silvassa on 7th March and at around 2 PM he will inaugurate the NAMO Hospital (Phase I). At around 2:45 PM, he will also inaugurate and  lay the foundation stone of multiple development projects for the UT worth over Rs 2580 crore at Silvassa. Thereafter, he will travel to Surat and at around 5 PM, he will launch the Surat Food Security Saturation Campaign. On 8th March, Prime Minister will travel to Navsari and at around 11:30 AM, he will interact with Lakhpati Didis which will be followed by a public function which will witness the launch of various schemes.

    PM in UT of Dadra and Nagar Haveli and Daman and Diu

    Boosting healthcare facilities in all corners of the country has been a primary focus of the Prime Minister. In line with this, he will inaugurate NAMO Hospital (Phase I) in Silvassa. This 450 bedded hospital, built at the cost of over Rs 460 crore, will significantly strengthen healthcare services in the Union Territory. It will provide state-of-the-art medical care to the people in the region, especially the tribal communities.

    Prime Minister will inaugurate and  lay the foundation stone of multiple development projects for the UT worth over Rs 2580 crore at Silvassa. These include various village roads and other road infrastructure, schools, health and wellness centres, Panchayat and administrative buildings, Anganwadi centres, water supply and sewage infrastructure among others. These projects aim to improve connectivity, promote industrial growth, encourage tourism, create employment opportunities and aim at enhancing public welfare initiatives in the region.

    Prime Minister will distribute appointment letters under Rozgar Mela. He will also distribute benefits to the beneficiaries under PM Awas Yojana – Urban, Gir Adarsh Aajeevika Yojana and Sylvan Didi scheme.

    Gir Adarsh Aajeevika Yojana aims to boost economic empowerment of women belonging to scheduled castes (SCs), scheduled tribes (STs), other backward classes (OBCs), minorities and divyangjan in the region through setting up small dairy farms and bringing social and economic changes in their lives. The Sylvan Didi scheme is an initiative to uplift women street vendors by providing them with aesthetically designed carts, with co funding from PM SVANIDHI scheme.

    PM in Gujarat

    On 7th March, Prime Minister will launch the Surat Food Security Saturation Campaign Programme in Limbayat, Surat and distribute the benefits under National Food Security Act to over 2.3 lakh beneficiaries.

    Women empowerment has been a cornerstone of the work done by the government. Guided by the vision of the Prime Minister, the government has been committed to taking steps towards their all round development. In line with this, on 8th March, on the occasion of International Women’s Day, Prime Minister will participate in the Lakhpati Didi programme in Vansi Borsi village in Navsari district and interact with the Lakhpati Didis. He will also felicitate 5 Lakhpati Didis with Lakhpati Didi Certificates.

    Prime Minister will launch the G-SAFAL (Gujarat scheme for Antyodaya Families for Augmenting Livelihoods) and G-MAITRI (Gujarat Mentorship and Acceleration of Individuals for Transforming Rural Income) programme of the Government of Gujarat.

    The G-MAITRI scheme will provide financial assistance and handholding support to Startups which are working for creating a conducive environment for rural livelihoods.

    G-SAFAL will provide financial assistance and entrepreneurial training to SHG women of Antyodaya families in two Aspirational districts and thirteen Aspirational Blocks of Gujarat.

     

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    MIL OSI Asia Pacific News –

    March 8, 2025
  • MIL-OSI USA: Grateful Heart Attack Survivor Gives $1.5 Million to UConn School of Medicine

    Source: US State of Connecticut

    Donald Reefe thought something was a little off when he had a nagging ache between his shoulders in December 2023. But he never imagined that a few weeks later he would end up in UConn Health’s Pat and Jim Calhoun Cardiology Center receiving life-saving treatment for a heart attack.

    “I attribute my recovery to the hospital, of course,” says Reefe. “As well as the quick work of the doctors, the nurses, and the support staff.”

    Reefe and his wife of 57 years, Jean, are thanking his care team by leaving a $1.5 million bequest to the UConn School of Medicine. The Donald and Jean Reefe Family Fund for Cardiology will support clinical technology, education, and research at the Calhoun Center.

    Donald and Jean Reefe (contributed photo).

    “I am very grateful to the Reefes for their support and generosity,” says UConn School of Medicine Dean Dr. Bruce T. Liang. “I am proud of our cardiologists, providers, and researchers who bring cutting edge medical advances to benefit our patients”.

    Life-Saving and Compassionate Care

    Reefe knew something was wrong when he awoke one morning and felt pressure in his chest following an intense dizzy spell the night before. He called 911 and was rushed to the emergency room at UConn Health. Dr. Michael A. Azrin led the care team.

    “Dr. Azrin came in and knew right away what was going on,” Reefe explains. “I don’t know how he determined it so quickly. I remember him saying the stent I needed was available and then I went right to the catheterization lab. It couldn’t have been more than 20 minutes from when I first arrived.

    “I looked at the doctor, he looked at me, and I had that almost overwhelming feeling that I was in good hands. I trusted him.”

    “They are very in tune with the patient and the family, which you don’t see everywhere,” Jean Reefe adds. “The doctor came up to me after and we had a real conversation. I never had a feeling they weren’t listening to us.”

    Recognizing and Preventing Heart Disease

    Heart disease, especially heart attack and stroke, is the leading cause of death in both men and women in the U.S. Don’t ever ignore or delay emergency care for these heart attack warning signs:

    Sudden chest pain, heaviness, or tightness/squeezing
    Shortness of breath
    Sweating or lightheadedness
    Dizziness
    Nausea
    Indigestion, heartburn, or an esophageal burning sensation.

    Dr. Maxwell Eder, assistant professor of cardiology in the School of Medicine, advises three ways to prevent heart disease.

    First, eat a daily diet rich in fruits, vegetables, and high in fiber.

    Second, stay active weekly with brisk walking or other vigorous exercise. The official recommendation for exercise by the American Heart Association (AHA) is 150 minutes of moderate aerobic activity or 75 minutes of vigorous activity per week with strength training two days per week.

    Lastly, don’t ever smoke, or quit smoking now.

    MIL OSI USA News –

    March 8, 2025
  • MIL-OSI Global: Ilona Maher and the myth of feminine fragility – how one rugby player is reshaping sport

    Source: The Conversation – UK – By Sheree Bekker, Associate Professor, Department for Health, University of Bath

    American rugby player Ilona Maher has risen to global fame. Not just because of her athletic ability (though that is remarkable, winning an Olympic bronze in 2024 in the USA rugby sevens team, and now signing a professional contract with England’s Bristol Bears), but because of what she represents.

    Maher received widespread attention during the Paris Olympics as she shared her journey to sporting success and acceptance on TikTok. It’s a streak she’s continued with a recent turn on the US reality contest Dancing With the Stars, in which she finished second.

    Now in Bristol to play 15-a-side rugby in preparation for the 2025 World Cup, Maher’s popularity (she has 3.4 million followers on Tiktok, more than any other rugby player in the world, of any gender) signals a generational shift. One that is increasingly rejecting outdated notions of femininity, fragility and women’s place in sport.

    Maher is unapologetically big, strong and bold, embodying traits that women have historically been told they shouldn’t possess. She doesn’t shy away from expressing herself. Instead, she has expanded the western cultural model of what strength and confidence can look like.

    On Dancing with the Stars, Maher reversed conventional gender roles by lifting her partner during routines. After the show, she spoke candidly about the financial challenges of being a professional athlete in women’s rugby. She highlighted how lack of investment in the sport has forced her to find additional ways to sustain her career, such as participating in the dance show.

    Maher lifted her partner on Dancing with the Stars.

    Breaking barriers

    This rebellion against gender norms is both personal and political. Sport has long been a site of this struggle for women.

    Participation itself was once radical, as women had to fight just to step onto the field. When American runner Bobbi Gibb broke the rules to run the Boston Marathon in 1966, it was a subversive act that sparked backlash. She ran without permission, having been told women weren’t capable enough, and completed the race easily.

    In our new book, Open Play: The Case for Feminist Sport, we explain how women who excelled in physically demanding sports were often vilified for threatening the traditional gender norms that placed them in passive or nurturing roles, rather than active, competitive ones.

    Athletes who showed strength, endurance and skill in these domains challenged deeply ingrained stereotypes of women as physically inferior and fragile. As a result, they faced intense scrutiny, both socially and publicly. Their achievements were often dismissed as anomalies, and they were frequently subject to sexist criticism, questioning their femininity or even whether they were “real” women at all.

    Maher, too, has faced this misogynistic criticism, with online trolls questioning her gender identity. She has spoken openly about the shame she felt as a child, growing up in a body which defied traditional expectations of femininity that are defined by smallness. Yet by confronting these prejudices, she offers the world a new example of what a woman’s body – and a woman’s power – can look like and do.

    Feminism and sport

    Feminism has historically focused on achieving equality in social, political and economic realms. Yet thinkers like Mary Wollstonecraft recognised early on that physicality was central to maintaining men’s dominance. Wollstonecraft argued in 1792 that women’s perceived physical inferiority wasn’t natural, but a product of their subjugation.

    Sport has since become a pivotal arena for challenging the myth of feminine fragility, which persists in part because of the supposedly objective proof that men outperform women in many physical feats. But Wollstonecraft’s insights remain relevant: men and women still do not compete on equal terms. Women’s sports receive a fraction of the funding, resources and cultural support of men’s.

    And the inequalities extend far beyond economic and cultural support. Women are often discouraged from participating in sport, and shamed if they excel.

    We argue that the segregation of women’s sport, often framed as necessary to “protect female athletes”, actually perpetuates inequality. Around the world, women are still barred from competing against men no matter how exceptional they are, while men retain access to the best facilities, funding and opportunities.

    In our book, we argue that this structural segregation reinforces the myth of women’s inferiority while denying women and other athletes with marginalised gender identities the chance to push boundaries and showcase their full potential. Ending this segregation would challenge the narrative of feminine fragility and open the best of sport to everyone.

    We believe that Maher embodies this challenge. Her fans see in her a bold rejection of outdated gender stereotypes and a celebration of what women can achieve when given the chance. But her visibility also threatens those invested in maintaining traditional hierarchies. The backlash she faces is a reminder of how high the stakes are.

    Sheree Bekker is Co-Director of the Feminist Sport Lab. She is also affiliated with the UK Collaborating Centre on Injury and Illness Prevention in Sport, an International Olympic Committee Research Centre.

    Stephen Mumford is Co-Director of the Feminist Sport Lab.

    – ref. Ilona Maher and the myth of feminine fragility – how one rugby player is reshaping sport – https://theconversation.com/ilona-maher-and-the-myth-of-feminine-fragility-how-one-rugby-player-is-reshaping-sport-248395

    MIL OSI – Global Reports –

    March 8, 2025
  • MIL-OSI Asia-Pac: Union Home Minister and Minister of Cooperation, Shri Amit Shah inaugurates the Sri Vishweshathirtha Memorial Hospital in Bengaluru, Karnataka

    Source: Government of India

    Union Home Minister and Minister of Cooperation, Shri Amit Shah inaugurates the Sri Vishweshathirtha Memorial Hospital in Bengaluru, Karnataka

    Sri Vishweshathirtha Memorial Hospital will serve as a modern center for free treatment for the poor and marginalized, providing services to people for many years to come

    The Pejawar Mutt has earned a respected place across the country by promoting national unity, preventing forced conversions, supporting the Ram Mandir movement, and serving Sanatan Dharma

    Sri Vishweshathirtha Swamiji, who took sanyas at the age of 8, dedicated his life to society, religion, and community

    Swamiji combined religious teachings with modern education and dedicated his entire life to education, service, healthcare, and the promotion of the Vedas

    Sri Vishweshathirtha Swamiji made a significant contribution in preventing the division of Hindu society into castes in South India

    Sri Krishna Seva Ashram Trust, established by the revered Sri Vishweshathirtha Swamiji, has always worked for the service of the poor and marginalized people in society

    Posted On: 07 MAR 2025 4:38PM by PIB Delhi

    Union Home Minister and Minister of Cooperation, Shri Amit Shah inaugurated the Sri Vishweshathirtha Memorial Hospital in Bengaluru, Karnataka today.

    In his address, Union Home Minister and Minister of Cooperation Shri Amit Shah said that today, the 150-bed Multi-Speciality Sri Vishweshathirtha Memorial Hospital has been inaugurated in Bengaluru, Karnataka, on a 2-acre land at a cost of ₹60 crore. He mentioned that this modern center for free treatment for the poor and underprivileged sections of society will serve people for many years to come. He said that 60 per cent of the beds in this hospital have been reserved for the poor, and the center is equipped with several state-of-the-art services. Shri Shah mentioned that the Sri Krishna Seva Ashram Trust has always worked for the service of the poor and marginalized sections of society. He noted that this trust was founded by the revered Sri Vishweshathirtha Swamiji, and today his successor, Sri Vishwprasannteerth Swamiji, is carrying forward this tradition. He added that the Sri Krishna Medical Center, Sri Krishna Netralaya, Dental Center, and Sri Vishwprasannteerth Memorial Clinic have been established. He emphasized that there cannot be a better treatment center for the poor in Bengaluru than this one.

    Union Home Minister and Minister of Cooperation Minister said that the Pejawar Mutt is not only a prominent mutt in Karnataka and South India but also in all of India, serving as a beacon of light. He mentioned that under the leadership of Sri Sri Vishweshathirtha, the Pejawar Mutt has earned a respected place across the country for its long-standing efforts in promoting national unity, preventing forced conversions, supporting the Ram Mandir movement, and serving Hindutva and Sanatan Dharma throughout South India and the nation. Shri Shah added that the Pejawar Mutt, located in Udupi, is one of the eight Mutts and has played a significant role in guiding many people on the path of devotion to Lord Krishna, following the teachings of Sri Madhvacharya.

    Shri Amit Shah said that finding a saint like Sri Vishweshathirtha Swami is extremely rare in today’s times. He mentioned that Swamiji lived his life for society, religion, and community, taking sanyas at the age of 8 and dedicating his eight decades of life to spirituality. He added that Swamiji was always at the forefront not only in serving Hinduism but also in serving society and the nation. Shri Shah further stated that Prime Minister Shri Narendra Modi conferred the Padma Vibhushan on Swamiji in 2020.

    Union Home Minister said that Swamiji has always worked for national unity. He mentioned that Swamiji played a significant role in preventing the division of Hindu society into castes in South India. He added that Swamiji dedicated his entire life to education, service, healthcare, and the propagation of the Vedas. Shri Shah also said that Swamiji worked to combine religious teachings with modern education. He mentioned that today, Swamiji’s tradition is continuing, and the Udupi Mutt holds great expectations for the country. He highlighted that the Pejawar Mutt played a crucial role in the religious ceremonies of Lord Ram’s consecration at the Ram Mandir. Shri Shah further stated that when Shri Narendra Modi became the Prime Minister of India in 2014, Swamiji was one of the prominent saints who went to Delhi to bless him.

    Shri Amit Shah said that Prime Minister Shri Narendra Modi has focused a great deal on the health and wellness of the people over the past 10 years. He mentioned that campaigns like Swachh Bharat Abhiyan, Fit India Movement, Nutrition Mission, Mission Indradhanush, Ayushman Bharat Yojana, and Jal Jeevan Mission are different components of the Healthy India campaign. He emphasized that cleanliness can manage health, fitness can make health eternal, and only nutritious and balanced food can keep the human body healthy. Shri Shah further stated that Mission Indradhanush covers all types of vaccinations, the Jal Jeevan Mission has ensured fluoride-free water reaches every home, and under the Ayushman Bharat scheme, Prime Minister Modi has provided free treatment up to ₹5 lakh for 60 crore people. He also mentioned that these health initiatives will not succeed unless religious and service-oriented organizations actively promote them. He concluded by stating that the hospital built in memory of Swamiji will play a significant role in keeping society healthy.

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    Read this release in: Hindi

    MIL OSI Asia Pacific News –

    March 8, 2025
  • MIL-OSI Asia-Pac: Celebration of 75th Anniversary of NSS by National Statistics Office (Field Operations Division), Regional Office, Sambalpur, MoSPI, Govt. of India

    Source: Government of India

    Posted On: 07 MAR 2025 4:48PM by PIB Delhi

    As part of celebration of 75th Anniversary of NSS, commemorating its transformative role in shaping India’s evidence-based policy making, an awareness campaign was organized by National Statistics Office (Field Operations Division), Govt. of India, Regional Office, Sambalpur at the 20th Annual Conference of Indian Association for Social Science and Health (IASSH) organized by Sambalpur University at Biju Patnaik Auditorium.The campaign was organized on 05.03.2025 and 06.03.2025. Publicity materials were displayed and distributed among the 250 nos. of participants of the conference.

    A plenary sessionwas conducted by NSO(FOD) RO, Sambalpur on the theme “Data for Development” on 06.03.2025. The session was chaired by Prof R. Nagarajan, IIPS Mumbai & Prof. Pradeep Kumar Panda from AIPH University, Bhubaneswar was the co-chair. Sh. Rahul Kumar Patel, Deputy Director & Regional Head, NSO(FOD) RO Sambalpur was the speaker. Importance of NSS data for policy formulation and decision making for the development and nation building were highlighted. A documentary about evolution of NSS during the last 75 years was also displayed. Information onrecently completed as well as ongoing surveys such as Periodic Labour Force Survey (PLFS), Household consumption Expenditure Survey (HCES), Annual Survey of Unorganized Sector Enterprise (ASUSE), Annual Survey of Industries (ASI), Socio-economic survey 80thround (Health & Telecom), Pilot study on Annual Survey of Service Sector Enterprises (ASSSE), Price Collection, Forward Looking Survey on Private Corporate Sector Capex Investment Intentions etc.,wasshared with the participants.As the participants were mostly the post-graduate students, researchers, academicians etc., hence process to access the unit level data of various surveys under NSO was also explained for the benefit of the participants. 

    Prof. R. Nagarajan and Prof. Pradeep Kumar Panda congratulated NSS for completing 75 years of successful data collection, dissemination and also stressed the importance of NSS data and how it has helped Govt, researchers, policy makers in decision making, economic growth and resource allocation.

    Shri S.C.Bhoi, SSO, Shri K.Padhan, SSO, Shri J.K.Singh, JSO, Shri P.Panigrahi, SS, Shri Balaram Behera, SE and Shri R.K.Mohanty, ASS of NSO (FOD), RO, Sambalpur were also present on the occasion.

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    MIL OSI Asia Pacific News –

    March 8, 2025
  • MIL-OSI United Kingdom: International Women’s Day: Liz Saville Roberts calls for stronger protections against violence and harassment at work

    Source: Party of Wales

    ‘We must use all the powers we have at our disposal to keep women safe’ – Liz Saville Roberts MP

    Today (Thursday 6 March), ahead of International Women’s Day, Plaid Cymru’s Westminster leader, Liz Saville Roberts MP has delivered a speech in Parliament urging stronger protections against gender-based violence and harassment in the workplace.

    Highlighting the urgent need for action, Ms Saville Roberts introduced the Health and Safety at Work etc. Act 1974 (Amendment) Bill, which is set for its second reading on 7 March.

    Developed in collaboration with the Suzy Lamplugh Trust and Rights of Women, the Bill seeks to amend the Health and Safety at Work etc. Act 1974 to place a legal requirement on employers to take proactive measures to prevent violence and harassment in the workplace.

    It also provides enhanced protections for women and girls and requires the Health and Safety Executive (HSE) to develop and publish a comprehensive framework on workplace violence and harassment.

    Currently, the HSE does not classify gender-based violence as a workplace hazard and is not regarded as the primary authority for issues such as harassment, bullying, or domestic abuse in professional settings. This Bill would change that, ensuring that gender-based violence is addressed as a serious workplace safety issue.

    During a debate in the House of Commons to note International Women’s Day, Liz Saville Roberts MP said:

    “When we talk about a gender equal society, let’s be clear about where we mean. In the home, in public spaces, in the workplace.

    “A 2023 TUC poll found that three in five women had experienced sexual harassment, bullying or verbal abuse in the workplace.

    And reports of sexual assault, rape, stalking and coercive control from colleagues make up 56% of calls made to Rights of Women’s Sexual Harassment at Work advice line. But as it stands, protections are limited.

    “The Workers Protection Act 2023 created a “preventative duty” for employers to take reasonable steps to prevent sexual harassment in the workplace.

    “But an automatic investigation into a breach of this duty only takes place after an individual successfully brings a claim of sexual harassment. And many other forms of gender-based violence in the workplace are excluded.

    “Meanwhile, the Health and Safety at Work Act 1974 already places a duty on employers to ensure the health, safety, and welfare of employees at work.

    “So why not use the toughest mechanism we have in the workplace to tackle workplace gender-based harassment and violence too?

    “That’s exactly what my Health and Safety at Work etc. Act 1974 (Amendment) Bill, developed with the brilliant Suzy Lamplugh Trust and Rights of Women, seeks to do.”

    Ms Saville Roberts closed:

    “If these are the differences we wish to make to women’s lives in the workplace, let us use all the powers we have at our disposal and make them work for women more effectively than they presently do.”

    MIL OSI United Kingdom –

    March 8, 2025
  • MIL-OSI United Kingdom: £7 million pilot now underway across all ten local authorities to help residents stay in work

    Source: City of Salford

    • Greater Manchester is one of 15 areas selected to pilot the WorkWell service, running until 31st March 2026.
    • Awarded £7million in Government funding to offer tailored support for people struggling to stay in work due to health issues or disabilities, as well as for those who have recently left work due to poor health, helping them return to employment.
    • Part of the city-region Live Well initiative, WorkWell ensures access to health and wellbeing support across every neighbourhood in Greater Manchester.
    • If you’re struggling to stay in work due to health issues, contact WorkWell today. Visit your local council website or call for more information and support.
    • The pilot aims to help around 8,000 local people.

    How WorkWell works?

    The WorkWell service takes a personalised approach by matching individuals with a dedicated work and health coach. These coaches help people access the right services to improve their wellbeing and job prospects. They offer guidance on overcoming barriers to work and can refer individuals to healthcare professionals for support with physical and mental health needs, including musculoskeletal conditions (MSK) and anxiety. By offering early support, such as physiotherapy, talking therapies, and lifestyle advice, WorkWell helps people stay well and prevent their health needs from getting worse.

    Additionally, coaches support individuals in building skills, finding suitable job opportunities, and creating tailored CVs and cover letters. They guide participants through interview preparation, offering practical advice to build confidence. Coaches also explore flexible work options that meet personal needs and connect individuals to local community groups for extra resources and support. These services are available both by phone and in person, providing flexible access to support.

    WorkWell is delivered in partnership by NHS Greater Manchester, the Greater Manchester Combined Authority (GMCA), local authorities, health organisations, and community groups. It forms part of a £64 million national programme from the Department for Work and Pensions (DWP) and the Department of Health and Social Care (DHSC) to improve health and employment outcomes across the country.

    A key part of Greater Manchester’s Live Well commitment

    The WorkWell pilot is an essential part of Greater Manchester’s broader Live Well commitment, which aims to tackle health, social, and economic inequalities by transforming how public services are delivered. Live Well is focused on ensuring that everyone has access to the right support, resources, and opportunities to lead a healthy, fulfilling life.

    Through combining personalised job and health support within local communities, WorkWell builds on the success of Greater Manchester’s flagship Working Well programme, which has already supported over 80,000 residents and helped nearly 30,000 people into employment.

    Greater Manchester’s Live Well Plan has also been awarded a £10 million funding boost to tackle inequalities, improve health, and support people in returning to work. This investment is part of the city-region’s ongoing commitment to helping those facing employment barriers due to health challenges. Funded through the “Get Britain Working White Paper”, the boost will build on initiatives like WorkWell, offering tailored support to individuals with health-related barriers to employment.

    Providing early support to prevent long-term unemployment

    Early intervention is key. Findings from the Working Well: Work and Health Programme show that people unemployed for up to six months have the highest chance of finding a job (49.7%). However, this likelihood decreases the longer someone is out of work, dropping to just 13.6% after ten years. By acting early, WorkWell aims to prevent long-term job losses due to health conditions.

    Who can access WorkWell?

    • WorkWell is available to anyone aged 16 or older, who is eligible to work in the UK.
    • Open to self-referrals or referrals via GPs and pharmacists, employers, or community organisations.
    • Available to Greater Manchester residents or anyone registered with a GP or JobCentre Plus in the area.

    NHS Greater Manchester and the Greater Manchester Combined Authority are encouraging local employers to learn more about WorkWell and how they can support employees with health conditions to remain in work. Employers can access guidance on workplace adjustments and additional resources.

    Mark Fisher, Chief Executive of NHS Greater Manchester, said:
    “This is really welcome news for Greater Manchester and the people who live here. Unfortunately, too many people in our city-region are unable to work due to poor health, and this has a profound impact on their lives and wellbeing.

    “The longer people are out of work, the harder it is to get back into employment. That’s why being part of the WorkWell pilot is so important. Over the next two years, we will support at least 8,000 local people to remain in or return to work – something we know is truly life-changing.

    “This is not something we can do alone. To reach as many people as possible, we will build upon existing support services and work closely with our ten local authorities, the GMCA, and Greater Manchester’s vibrant voluntary sector. Most importantly, we will do this in partnership with local people to make a positive impact on their health and lives.”

    Mayor of Greater Manchester and Co-Chair of Greater Manchester Integrated Care Partnership, Andy Burnham said:
    “WorkWell is already improving people’s lives and is a key part of our effort to better connect health and employment support. By bringing these services together, we’re helping residents find work and build a better future.

    “The early success stories from WorkWell show what’s possible when we bring together our brilliant community groups, voluntary organisations, and the NHS. This is about removing barriers people face and making sure everyone in Greater Manchester gets the right support at the right time to improve their health and find good jobs. I’m proud that Greater Manchester is leading the way with this initiative.

    Mayor Burnham added, “The extra £10 million funding for Live Well, as part of the ‘Get Britain Working White Paper’ initiative, highlights our commitment to making Greater Manchester a city-region where everyone has access to the support needed to lead healthier lives and succeed in the workplace. This investment will have a real impact for those facing health challenges”.

    Accessing WorkWell

    If you or someone you know is facing health challenges that make it difficult to stay in work, don’t wait – reach out to WorkWell today! Visit your local council website and search for ‘WorkWell’, or head to the Greater Manchester Combined Authority website for more information on available services. You can also call your local council on their usual contact numbers. They will help you access the support you need.

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    Date published
    Friday 7 March 2025

    Press and media enquiries

    MIL OSI United Kingdom –

    March 8, 2025
  • MIL-OSI United Kingdom: Triple combination medicine deutivacaftor/tezacaftor/vanzacaftor approved for cystic fibrosis

    Source: United Kingdom – Government Statements

    Press release

    Triple combination medicine deutivacaftor/tezacaftor/vanzacaftor approved for cystic fibrosis

    In two randomised phase 3 studies involving 480 participants aged 12 years and over, ivacaftor/tezacaftor/vanzacaftor was found to be as effective at improving lung function as a currently approved triple combination therapy, and more effective at reducing sweat chloride levels. 

    The Medicines and Healthcare products Regulatory Agency (MHRA) has approved the triple combination medicine deutivacaftor/tezacaftor/vanzacaftor (brand name Alyftrek) to treat cystic fibrosis (CF) in people aged six years and older who have specific mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene that have been shown in trials to respond to the therapy. This includes F508del, which is the most common cystic fibrosis causing mutation.  

    Cystic fibrosis is an inherited condition caused by a faulty CTFR gene, which helps regulate the flow of water and chloride in and out of the lungs and other organs. This causes sticky mucus to build up in the lungs and digestive system, which can lead to lung infections and problems with digesting food.  

    Deutivacaftor/tezacaftor/vanzacaftor is a CFTR “modulator”, meaning it is designed to correct the malfunctioning protein made by the CTFR gene in people with cystic fibrosis. 

    Julian Beach, MHRA Interim Executive Director, Healthcare Quality and Access, said:

    “Keeping patients safe and enabling their access to high quality, safe and effective medical products are key priorities for us.  

    “We confirm that the appropriate regulatory standards for the approval of this medicine have been met. 

    “As with all products, we will keep its safety under close review.” 

    David Ramsden, Cystic Fibrosis Trust Chief Executive, said:  

    “Today’s MHRA approval is another important step in making sure as many people with CF as possible can benefit from the best available treatments. 

    “We now hope that NICE will move quickly to complete its assessment of the medicine to enable it to be prescribed on the NHS. 

    “Today is good news, but we never forget that these medicines are not a cure, and do not work for some people. Cystic Fibrosis Trust will not stop until everyone with CF can live a life that’s not limited by their condition.” 

    Deutivacaftor/tezacaftor/vanzacaftor is administered as a tablet once a day.  

    Food or drink containing grapefruit should be avoided during treatment.  

    In two randomised phase 3 studies involving 480 participants aged 12 years and over (studies 121-102 and 121-103), ivacaftor/tezacaftor/vanzacaftor was found to be as effective at improving lung function as ivacaftor/tezacaftor/elexacaftor (Kaftrio), a currently approved triple combination therapy, and more effective at reducing sweat chloride levels.  These findings are supported by additional data from an open‑label, phase 3 study (study 121-105, Cohort B1). 

    The most common side effects in the clinical trials were headache (15.8%) and diarrhoea (12.1%). For the full list of all side effects reported with this medicine, see Section 4 of the Patient Information Leaflet (PIL) or the Summary of Product Characteristics (SmPC) available on the MHRA website.  

    As with any medicine, the MHRA will keep the safety and effectiveness of deutivacaftor/tezacaftor/vanzacaftor under close review.  Anyone who suspects they are having a side effect from this medicine are encouraged to talk to their doctor, pharmacist or nurse and report it directly to the Yellow Card scheme, either through the website (https://yellowcard.mhra.gov.uk/) or by searching the Google Play or Apple App stores for MHRA Yellow Card.  

    Notes to editors   

    1. The new marketing authorisation was granted via a national route on 7 March 2025 to Vertex Pharmaceuticals (Europe) Limited. 

    2. More information can be found in the PIL and SmPC which will be published on the MHRA Products website within 7 days of approval.   

    3. For more information about cystic fibrosis, visit here.   

    4. The Medicines and Healthcare products Regulatory Agency (MHRA) is responsible for regulating all medicines and medical devices in the UK by ensuring they work and are acceptably safe.  All our work is underpinned by robust and fact-based judgements to ensure that the benefits justify any risks.   

    5. The MHRA is an executive agency of the Department of Health and Social Care.   

    6. For media enquiries, please contact the newscentre@mhra.gov.uk, or call on 020 3080 7651.

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    Updates to this page

    Published 7 March 2025

    MIL OSI United Kingdom –

    March 8, 2025
  • MIL-OSI USA: Attorney General James Sues Trump Administration over Mass Firings of Federal Workers

    Source: US State of New York

    EW YORK – New York Attorney General Letitia James and a coalition of 19 other attorneys general today filed a lawsuit against the Trump administration for illegally firing thousands of probationary federal workers, including hundreds in New York. The administration is required to provide advance notice of mass layoffs to employees and states so that states can mobilize resources needed to process unemployment claims and care for unemployed workers. However, as Attorney General James and the coalition argue in their lawsuit, the administration has directed federal agencies to conduct immediate mass terminations of probationary employees without following the law. The resulting unlawful layoffs have upended workers’ lives, disrupted essential services, and forced states to scramble to provide resources for recently fired workers.

    “Whether it’s providing health care to our veterans, keeping our communities safe, or ensuring our children get a quality education, federal employees provide essential services every day,” said Attorney General James. “The Trump administration’s illegal mass firings of federal workers are a slap in the face to those who have spent their careers serving our country. Thousands of workers across New York and the nation are now struggling to pay rent, put food on the table, and care for their loved ones. Today, I am joining my fellow attorneys general in defending the rights of workers who serve our communities and stopping the chaos and confusion this unjust policy is causing.” 

    In New York, these illegal layoffs have impacted workers throughout the state. In the last week of February, 372 federal workers had filed for unemployment in New York. More than 1,000 Department of Veterans Affairs (VA) employees nationwide were fired in February, including workers at VA medical centers in New York. Workers at the U.S. Centers for Disease Control and Prevention (CDC) who were fired included seven staffers assigned to New York City’s Department of Health and Mental Hygiene. In Buffalo and Syracuse, more than 100 Internal Revenue Service (IRS) employees have been fired, leaving New Yorkers without a critical resource for assistance with their tax returns at the height of tax season. The regional office of the National Labor Relations Board (NLRB) in Buffalo also saw major staffing cuts, jeopardizing the rights of workers across Western New York.

    The probationary employees that the Trump administration has targeted are workers who have either been newly hired or have recently been promoted or changed offices. They are generally subject to a probationary period of one or two years.

    In their lawsuit, Attorney General James and the coalition argue that the Trump administration has violated the law by implementing mass layoffs, or Reductions in Force (RIF), without providing states and employees proper advance notice. Federal agencies are required by law to provide at least 60 days of prior written notice before they release any federal civil service employee under a RIF. These notices help states assemble job training programs, staff to process unemployment claims, and other resources to minimize the harm to affected workers and their communities.

    With this lawsuit, Attorney General James and the coalition are seeking a court order to stop further mass layoffs without notice and the reinstatement of all illegally fired federal workers who have been laid off since January 20, 2025.

    “Federal employees are the backbone of our nation’s operations, and their work is absolutely vital to the safety and well-being of every American,” said Congressman Dan Goldman. “The illegal mass firing of probationary employees is an unjust and reckless attack on the very workers who ensure our government functions. The federal workforce deserves our deepest respect, and the targeted layoffs of probationary employees will have a cascading effect, leading to a catastrophic loss of institutional knowledge that will be felt for generations. I applaud New York Attorney General James and the 16 other attorneys general for their bold and decisive action in filing this lawsuit to protect our dedicated federal workers, and, by extension, the integrity of our government.”

    “President Trump and Elon Musk have attacked our dedicated federal workforce, who process benefits for seniors and veterans, protect our natural resources, keep our skies safe, and so much more,” said Congressman Tim Kennedy. “No one is above the law, and today’s lawsuit will help ensure the President is held accountable for disrupting the lives of our civil servants and the hardworking families they serve in Western New York and across the country. I stand by Attorney General James as we come together to combat the Trump Administration’s reckless mass firings.”

    “Workers have rights in the United States, and it’s against the law – and against the interests of the American people who depend on critical services like Social Security – to indiscriminately fire dedicated public workers, including here in Central New York and the Mohawk Valley,” said Congressman John W. Mannion. “Trump and Musk’s efforts to illegally erase a century of hard-fought workplace protections must be stopped. On behalf of every worker in NY-22 – and every senior, veteran, farmer, and constituent who deserves a functioning and responsive government – I wholeheartedly support this legal action by Attorney General James and her counterparts.  We’ll see you in court, Mr. President.”

    “Instead of taking real action to lower costs or keep our communities safe, the Trump administration is gutting the workforce of those who provide care to our veterans, retirement for our seniors, and healthcare to our communities,” said Congressman Joe Morelle. “It’s shameful. I’m proud to support Attorney General James in her efforts to fight back and hold the President accountable.”

    “The Trump-Musk administration’s reckless and unlawful mass firings have been nothing short of a catastrophe—not just for the dedicated federal workers whose livelihoods have been upended, but for the millions of New Yorkers who rely on the essential services they provide,” said Congressman Jerrold Nadler. “If left unchallenged, these firings will undermine the very programs that working families, seniors, and people with disabilities in New York depend on every day. I am grateful that New York Attorney General James has taken swift action to challenge these illegal firings, and I am proud to stand with her and my fellow Congressional Democrats to send a clear message to our federal workers in New York: We stand with you, and we will not stop fighting until these outrageous and harmful actions are fully reversed.”

    Joining Attorney General James in filing today’s lawsuit are the attorneys general of Arizona, California, Colorado, Connecticut, Delaware, Hawaii, Illinois, Maryland, Massachusetts, Michigan, Minnesota, Nevada, New Jersey, New Mexico, Oregon, Rhode Island, Vermont, Wisconsin, and the District of Columbia.

    MIL OSI USA News –

    March 8, 2025
  • MIL-OSI United Kingdom: Chief Inspector of Constabulary reappointed

    Source: Scottish Government

    Craig Naylor in post for a further three years.

    Craig Naylor has been reappointed as His Majesty’s Chief Inspector of Constabulary in Scotland for an additional three years.

    Mr Naylor, who first took up the role in 2022, will continue to lead HM Inspectorate of Constabulary Scotland (HMICS) to deliver a programme of independent inspection, monitoring and evaluation of Police Scotland and the Scottish Police Authority.

    He will also be a source of professional independent advice on police matters, publish reports of inspections and produce an annual report to Ministers on the police service in Scotland.

    Justice Secretary Angela Constance said:

    “The role that HMICS plays in ensuring Scotland’s police officers and staff continue to perform their duties to a high standard, and that their systems and processes are accountable, is absolutely key to Scottish policing.

    “Craig’s first three years in post have been hugely productive, with scrutiny of roads policing, how Police Scotland manages mental health incidents and a series of joint inspections with Health Improvement Scotland among the significant reviews undertaken and published.

    “I am very pleased that Craig is remaining in post for another three years and look forward to the next HMICS scrutiny plan and continued constructive working to help maintain the high standard of policing in Scotland.”

    Mr Naylor said:

    “Over the last three years I have been honoured to serve as HM Chief Inspector of Constabulary in Scotland and I am delighted to have been reappointed for another three years.

    “I feel extremely privileged to lead a dedicated team of very talented inspectors and support staff, working together to help improve policing across Scotland, and look forward to continuing this important role.”

    Background

    Craig Naylor was first appointed as His Majesty’s Chief Inspector of Constabulary in Scotland on 17 March 2022, having been Deputy Director of Investigations at the National Crime Agency. He has more than 30 years policing experience and previously served with Police Scotland, where he held the role of Divisional Commander for Specialist Service and was responsible for firearms, public order, search and dogs. Prior to that, he worked in a number of roles across the former Lothian and Borders Police and the Scottish Crime and Drug Enforcement Agency.

    The appointment is made by Royal Warrant and the post is entirely independent of Government, police and the Scottish Police Authority.

    HM Inspectorate of Constabulary in Scotland is an independent scrutiny body, which has been in existence since the nineteenth century. HM Chief Inspector of Constabulary in Scotland is the senior professional police adviser to Scottish Ministers. The statutory duties of HMICS are set out in Chapter 11 of the Police and Fire Reform (Scotland) Act 2102. For more information on HMICS please go to www.hmics.scot. 

    HMICS have also confirmed that Mark Hargreaves will be vacating the Assistant Inspector of Constabulary post as he retires from Police Scotland. Brian McInulty, currently a Lead Inspector with HMICS, will take on this role on a temporary basis until a new appointment is made.

    MIL OSI United Kingdom –

    March 8, 2025
  • MIL-OSI United Kingdom: expert reaction to study looking at butter or vegetable oils and mortality

    Source: United Kingdom – Executive Government & Departments

    March 6, 2025

    A study published in JAMA Internal Medicine looks at butter and plant based oils intake and mortality.

    Prof Sarah Berry, Professor of Nutritional Sciences, King’s College London, said:

    “The study shows that high butter consumption is linked to increased cancer and total mortality, whereas plant-based oils are linked to a lower risk of overall mortality and death due to cardiovascular disease and cancer.

    “This research is very timely.  Social media is currently awash with influencers promoting butter as a health food and claiming that seed oils are deadly.  This large-scale, long-term study finds the reverse.  The authors produce further evidence that seed oil consumption is linked to improved health and that butter – delicious as it is – should only be consumed once in a while.

    “In a sane world, this study would give the butter bros and anti-seed oil brigade pause for thought, but I’m confident that their brand of nutri-nonsense will continue unabated.”

    Dr Louise Flanagan, Head of Research for the Stroke Association, said: 

    “Stroke is the fourth leading cause of death in the UK and a leading cause of adult disability – but, fortunately, nine out of 10 strokes can be prevented.  High blood pressure is the cause of around half of all strokes.

    “This study covered a wider range of plant oils than previous research to find that greater consumption of rapeseed oil, soybean oil or olive oil is associated with an overall lower risk of death.  It is positive to see other plant oils being considered in this way as olive oil has been a focus of much research in the past.

    “The suggestion to switch from butter to plant oils is achievable for many people.  However, it was only olive oil that was associated with a lower risk of death due to cardiovascular disease, including stroke.  Olive oil is typically more expensive than other oils like rapeseed which means that its potential health benefits could be out of financial reach for some.

    “The study didn’t consider what eating both butter and plant oils means in terms of health risks, which is likely to be what many people naturally do.  This is potentially something which could be considered in future studies.

    “The Stroke Association encourages people to maintain a healthy diet, exercise regularly, not smoke and monitor alcohol intake, which can help to maintain healthy blood pressure.  Anyone with concerns should speak to their GP.”

    Prof Parveen Yaqoob, professor of nutritional science at the University of Reading, said:

    “The link between diets high in saturated fat, particularly animal-based fat such as butter and lard, and higher mortality has been argued for decades.  I have seen American adverts from the 1960s extolling the virtues of American housewives “polyunsaturating” their husbands when they come home from work.  This is a fun historical reminder of the link between the food industry and dietary health messages, as well as showing how much woman have had to fight for social progress.

    “This latest research provides strong additional data to support the ‘healthier fats’ theory.  The research followed a large cohort of health workers in America over many years.  The use of food frequency questionnaires means that we are relying on the participants to remember what they have eaten and how much, which we know can be an unreliable indicator of actual dietary patterns.

    “The scientists for this study highlight that not all vegetable oils are equal.  Although butter was being replaced by corn oil and sunflower oil, which are polyunsaturated, in the 1960s and 70s, the oils they are talking about in the research – olive, canola and soybean – are mainly monounsaturated.  The researchers suggests that these are more beneficial than the polyunsaturated fats, and refer to the Mediterranean diet, which is higher in monounsaturated fats such as olive oil, for that reason.  While many Western diets shifted away from saturated fat to polyunsaturated fat in the 1970s, the oils that we consume more often now contain more monounsaturates, which seem to be more beneficial.  Given that there are some plant-based oils that are high in saturates – such as palm oil and coconut oil – it is important to consider them separately.

    “Recent dietary fads have suggested a re-examination of evidence on dietary fat.  People who are confused about these conflicting messages about their diet should focus on broader, well-established advice, which can be summarised as: eat more fresh vegetables.”

    Prof Tom Sanders, Professor emeritus of Nutrition and Dietetics, King’s College London, said:

    “This important study shows that people who chose to eat butter don’t live as long as those who chose to eat vegetable oils.  It is a well conducted prospective study of 221,054 health professionals who were in their fifties when enrolled and followed up for 33 years.  Dietary intakes were assessed every 4 years.  The study reports that those who had the highest intake of butter were 15% more likely to die prematurely (from both cardiovascular disease and cancer).  In comparison the opposite was true (a 16 % reduction in relative risk of all-cause mortality), for participants who had the highest intake of vegetable oil.  The same relationship was seen for olive oil, soybean oil and canola oil (rapeseed oil).

    “The strength of the study is the long period of follow-up, repeated measures of dietary intake and adjustment in the statistical analysis for other factors such as smoking habit and obesity.  The findings do not apply to sunflower, palm or coconut oils which were not consumed to any significant extent in this study.  The limitations are that this an observational study not a randomised controlled trial.  Furthermore, the findings with regard to health professionals may differ from the general population because they are better informed about healthy lifestyle choices.

    “Butter is high in saturated fat, contains some trans fatty acids but is very low in polyunsaturated fats.  Whereas unhydrogenated soybean, canola and olive oils are low in saturated fatty acids but high in unsaturated fats.  Replacement of butter with these vegetable oils is well documented to lower blood cholesterol, particularly that associated with low density lipoprotein (LDL) by about 10%.  This change in LDL cholesterol would be predicted to reduce the relative risk of death by about 3% which is much less than what was observed in this study.  It remains possible that a higher intake of polyunsaturated fatty acids (especially linoleic acid) from the vegetable oil may have played a role in reducing risk by a variety of mechanisms.  An alternative explanation may be that health professionals who are sensible follow prevailing healthy eating and lifestyle advice compared to those who don’t.

    “The take home message is that it is healthier to choose unsaturated vegetable oils rather than butter.  This is particularly relevant as there has been much negative publicity about vegetable oils on social media, which are based on unfounded claims of potential harmful effects, rather than deaths as described in the present study.”

    Prof George Davey Smith, FRS FMedSci, Professor of Clinical Epidemiology, University of Bristol, said:

    “Yet again these studies show that the exposure that is accompanied by large differences in other adverse health exposures – e.g. more than double the rate of cigarette smoking in the highest quartile vs lowest quartile of butter consumption is associated with worse health outcomes.  That these differences cannot be taken into account by the statistical models the authors use is well known; measurement error and unmeasured factors ensure this.  It is now more than 30 years since these authors published two high profile papers back to back in the New England Journal of Medicine claiming that vitamin E supplement use would reduce heart disease risk by 40%.  The claims were incorrect, but many people believed them – the story was the headline news in the New York Times – and started taking vitamin E supplements.  However randomised trials later showed this was nonsense: there was no benefit.  This is documented in the first few minutes of this recent talk https://www.youtube.com/watch?v=8IgpTT5ZXXU&t=2s  As in the conclusion of my blog1 on the same authors’ “dark chocolate” paper, the interesting question this paper raises is “why do supposedly legitimate journals keep publishing papers like this?”.”

    1 https://ieureka.blogs.bristol.ac.uk/2024/12/04/dark-chocolate-diabetes/

    ‘Butter and Plant-Based Oils Intake and Mortality’ by Yu Zhang et al. was published in JAMA Internal Medicine at 21:00 UK time on Thursday 6 March 2025.

    DOI: 10.1001/jamainternmed.2025.0205

    Declared interests

    Prof Sarah Berry: “Sarah has received funding from the Almond Board of California, Malaysian Palm Oil Board and ZOE (Chief scientist at ZOE Ltd, options and consultancy at ZOE Ltd.).”

    Dr Louise Flanagan: “None.”

    Prof Parveen Yaqoob: “Professor Parveen Yaqoob is Deputy Vice-Chancellor, and Pro-Vice-Chancellor (Research & Innovation) of the University of Reading, and professor of nutritional science in the Department of Food and Nutritional Sciences, which has funding from public bodies, charities and businesses to conduct independent scientific research on food and nutrition.

    The Department has done work on dietary fat, including research co-authored by Parveen as part of the DIVAS project: https://research.reading.ac.uk/ifnh/cases/milk-dairy-consumption-risk-cardiovascular-diseases-cause-mortality/  Mostly government or UKRI funded, with industry partners.  The papers listed from that project list grant numbers.

    Work on reducing saturated fat in dairy was a REF case study, which includes grant numbers from BBSRC and MRC, and had industry partners throughout, which is one of the ways in which the research was considered to have impact.

    https://results2021.ref.ac.uk/impact/eefa0a3d-4ba8-4419-8c28-836e06b41eed?page=1.”

    Prof Tom Sanders: “I am a member of the Programme Advisory Committee of the Malaysia Palm Oil Board which involves the review of research projects proposed by the Malaysia government.

    I also used to be a member of the Scientific Advisory Committee of the Global Dairy Platform up until 2015.

    I did do some consultancy work on GRAS affirmation of high oleic palm oil for Archer Daniel Midland more than ten years ago.

    My research group received oils and fats free of charge from Unilever and Archer Daniel Midland for our Food Standards Agency Research.

    Tom was a member of the FAO/WHO Joint Expert Committee that recommended that trans fatty acids be removed from the human food chain.

    Member of the Science Committee British Nutrition Foundation.  Honorary Nutritional Director HEART UK.

    Before my retirement from King’s College London in 2014, I acted as a consultant to many companies and organisations involved in the manufacture of what are now designated ultraprocessed foods.

    I used to be a consultant to the Breakfast Cereals Advisory Board of the Food and Drink Federation.

    I used to be a consultant for aspartame more than a decade ago.

    When I was doing research at King’ College London, the following applied: Tom does not hold any grants or have any consultancies with companies involved in the production or marketing of sugar-sweetened drinks.  In reference to previous funding to Tom’s institution: £4.5 million was donated to King’s College London by Tate & Lyle in 2006; this funding finished in 2011. This money was given to the College and was in recognition of the discovery of the artificial sweetener sucralose by Prof Hough at the Queen Elizabeth College (QEC), which merged with King’s College London. The Tate & Lyle grant paid for the Clinical Research Centre at St Thomas’ that is run by the Guy’s & St Thomas’ Trust, it was not used to fund research on sugar. Tate & Lyle sold their sugar interests to American Sugar so the brand Tate & Lyle still exists but it is no longer linked to the company Tate & Lyle PLC, which gave the money to King’s College London in 2006.”

    MIL OSI United Kingdom –

    March 8, 2025
  • MIL-OSI China: NHC minister meets with Tunisian minister of health

    Source: People’s Republic of China Ministry of Health

    Lei Haichao, minister of China’s National Health Commission, met with Tunisian Minister of Health Mustapha Ferjani in Beijing on Feb 26. The pair discussed strengthening bilateral cooperation and signed a memorandum of understanding on health exchanges and cooperation between the two countries.

    Lei welcomed Ferjani to China, noting that China and Tunisia enjoy a profound friendship and have maintained long-term friendly cooperation in the health sector.

    He said that China is thoroughly implementing the guiding principles of the 20th National Congress of the Communist Party of China (CPC) and the second and third plenary sessions of the 20th CPC Central Committee, advancing a health-first strategy and further deepening the reform of the medical and health system to build a Healthy China.

    He added that China is ready to work with Tunisia to advance the Partnership Action for Health proposed at the Beijing Summit of the Forum on China-Africa Cooperation in 2024 and deepen practical cooperation in health policy, traditional medicine, public health, digital health and the pharmaceutical industry, so as to promote the building of a global community of health for all.

    Ferjani spoke highly of China’s achievements in the health sector and expressed gratitude for China’s long-term selfless medical assistance. He said Tunisia looks forward to learning from China’s development experience, and deepening bilateral health cooperation to continuously improve the health and well-being of the two peoples.

    MIL OSI China News –

    March 8, 2025
  • MIL-OSI Economics: [World Sleep Day] Recovering From Daylight Savings May Take More Than Three Weeks, Youngest Hit Hardest

    Source: Samsung

    Do you find yourself feeling more tired once the clocks spring forward for Daylight Savings Time (DST)? Well, you’re not alone. Although losing an hour the night of DST may seem insignificant, examining the sleep patterns of global Samsung Health user’s[i] from the US, Canada and more than 40 European countries reveals a ripple effect that causes weeks-long disruptions to sleep patterns, hitting younger age groups the hardest.
     
    DST Takes a Toll on Sleep, With Younger Generations Most Disrupted
    When looking into how much of an impact DST has on people the morning after, one thing is clear, everyone’s sleep patterns are thrown off. In fact, people spent a little too much time counting sheep the night of the time change, falling asleep 33 minutes later than the previous night, waking up 19 minutes earlier. While losing sleep isn’t easy at any age, those in their 20s likely felt it the most thanks to an extremely late bedtime and a seeming inability to sleep in.
     

     
    Moreover, Sleep Score – calculated based on an evaluation of a users’ total sleep time, awake time, sleep cycle, plus physical and mental recovery – was at the worst level for weeks after DST – and again, people in their 20s appeared to be most affected. When examining in the seven-day Sleep Score average, the 20s age group demonstrated the slowest score recovery rate, while older age groups adapted much quicker. By the third week, Sleep Score for all age groups were still not stable as normal, showing fluctuations in the quality of a good night’s rest.
     

     
    Useful Tips To Help You Get a Good Night’s Sleep and a Quicker Recovery
    The transition into DST clearly affects the sleep patterns of all age groups long after the clocks change, but for younger generations, prioritising sleep management during this time couldn’t be more important. In recognition of World Sleep Day, Samsung is sharing useful tips that make understanding your sleep patterns and habits as seamless and effortless as possible for a better night’s rest.
    Creating an ideal sleep environment is critical to a good night’s sleep. Later this month, Samsung Health app update[ii] will make this possible by providing guidance and analysis on the key factors that influence sleep quality, including temperature, humidity, CO2 and illuminance via a Sleep Environment Report[iii] – leveraging SmartThings and the power of Samsung’s extensive device ecosystem. With a better understanding of how your environment affects sleep, easily optimise your room conditions for an improved night’s rest.
     
    In addition to perfecting your sleep environment, understanding how activity can impact energy level is key. Samsung Health app updates also bring enhancements to Energy Score[iv], which provides an indicator of how much energy users can expend throughout the day. In addition to sleep and heart rate, a new detailed factor about activity – Activity Consistency – will help you understand your overall condition in greater detail by evaluating your activity levels over the past four weeks.
     
    It’s also important to understanding how you’re sleeping and making necessary adjustments through sleep training. Sleep Coaching makes this simple by seamlessly tracking your sleep patterns over 7 days and assigning a sleep animal based on the results. With a personalised coaching program, develop healthy habits and routines that set you on a positive path to achieving your sleep goals.
     
    World Sleep Day serves as an important reminder of the importance of sleep. With the latest Samsung Health app updates and the Galaxy ecosystem, Samsung remains committed to helping users optimise their sleep and lead healthier, more balanced life.
    [i]Findings analysed sleep data of Samsung Health users via Galaxy Watch series during DST in the spring of 2024.
    [ii]Certain features may vary by market, carrier or paired device.
    [iii]Sleep Environment Report feature will be available on smartphone with One UI 7 and Samsung Health app version 6.29.5 or higher, and when device is connected to SmartThings.
    [iv]Galaxy AI features track data and require compatible Samsung Galaxy phone, Samsung Health app and Samsung account.

    MIL OSI Economics –

    March 7, 2025
  • MIL-OSI Europe: Academic freedom and democracy under siege: how a Nobel peace prize could help defend them

    Source: Universities – Science Po in English

    Echoing the Stand Up for Science movement, which was organised in the US to defend academic freedom, a call to mobilise in France has been launched for Friday, 7 March. Conferences, rallies and marches are being organised on the initiative of scientists united under the banner of Stand Up for Science France. Sciences Po, along with its partner The Conversation, has been committed from the outset to supporting those who advance research.

    March 7 has been recognized as the “Day of the Stand Up for Science Movement”, launched in 2017 in response to the anti-science actions of the first Trump administration. Under the second, attacks on scientists and scientific inquiry have escalated into a systematic assault–tantamount to a coup d’Etat against science itself.

    While Donald Trump is often portrayed as erratic, his policies in this area have followed a consistent trajectory. His new administration has once again declared ‘war’ on evidence-based national policymaking and science diplomacy in foreign affairs as evidenced by several early actions. Immediately after taking office, Donald Trump issued executive orders freezing or canceling tens of billions in research funding. All National Science Foundation projects have been halted pending review, while the National Institutes of Health faces suspensions under Health and Human Services directives. The US has withdrawn from the Paris Agreement and the World Health Organization, alongside a sweeping review of 90% of USAID-funded projects, signaling a major retreat from climate and global health diplomacy. Federal agencies and universities are in turmoil, leaving thousands of research-professors in limbo amid a politically driven funding freeze. The 2025 March simply calls for the restoration of federal research funding and an end to government censorship and political interference in science.

    The US is the world’s undisputed scientific superpower–for now

    While the Trump administration is not the sole force undermining academia worldwide, its actions are particularly striking coming from the world’s leading scientific superpower. Moreover, the situation is especially concerning because developments in the United States often have a ripple effect, shaping policies in other regions in the years that follow.

    Neither of the world’s top two scientific superpowers–Washington and Beijing–is positioned to champion academic freedom. China, having failed a liberal constitutional tradition and academic independence since the 1920s, restricts academic freedom to the confines of one-party rule. Caught between these rival scientific giants–both partners and competitors–the “old” Europe and like-minded coutries remain the only actors capable of setting new standards for academic freedom.

    A Nobel prize for academic freedom

    A decisive step toward its legal protection would be formal recognition by the Nobel Committees for Peace and Science of academic freedom’s fundamental role–both in ensuring scientific excellence and as a pillar of free, democratic societies.

    For the past decade, the Scholars at Risk association (SAR) has documented a broader global decline in academic freedom in its annual Free to Think Report. The 2024 edition highlights particularly alarming situations in 18 countries and territories (including the United States), which recorded 391 attacks on scholars, students, or institutions across 51 regions in a year. Data from the Academic Freedom Index in Berlin confirm that more than half of the world’s population lives in regions where academic freedom is either entirely or severely restricted. Some of the most concerning conditions are in emerging scientific ecosystems such as Turkey, Brazil, Egypt, South Africa, or Saudi Arabia. The overall trend is deteriorating: only 10 out of 179 countries have improved, while many democratic regimes are increasingly affected.

    Academic freedom in the European Union remains relatively high compared to the rest of the world. However, nine EU member states fall below the regional average, and in eight of them, it has declined over the past decade–signaling a gradual erosion of this fundamental value. Hungary ranks the lowest among EU countries, placing in the bottom 20–30% worldwide. Recent laws have further weakened university autonomy across the EU: financial autonomy in Austria, Italy, Luxembourg, the Netherlands, and Slovakia; organizational autonomy in Slovenia, Estonia, and Denmark; staffing autonomy in Croatia and Slovakia; and academic autonomy in Denmark and Estonia. Moreover, the European Parliament’s first report on academic freedom (2023) highlights emerging threats in France–political, educational, and societal–that impact the freedom of research, teaching, and study.

    Academic freedom, a professional right granted to a few for the benefit of all

    Freedom of expression, a fundamental pillar of academic freedom, has long been established as a human right, overcoming centuries of censorship and authoritarian control. In contrast, academic freedom is a more recent principle, granting scholars–recognized by their peers–the right and responsibility to research and teach freely in pursuit of knowledge. Like press freedom for journalists, it is a right granted to a few for the benefit of all.

    Rooted in medieval Europe, academic freedom has evolved from a privilege granted to students in the Quartier Latin to a recognized principle in international rights frameworks. It gained a collective and concrete dimension in the late 18th and early 19th centuries with the rise of the modern university. Wilhelm von Humboldt, founder of the modern public university in Berlin (1810), articulated the concept of ‘freedom of science’ (Wissenschaftsfreiheit), later enshrined in the Weimar Constitution of 1919, which declared that “art, science, and education are free.” The rise of American universities around the same time reshaped the concept, giving rise to “professional academic freedom.” This was formalized in the American Association of University Professors’ 1915 Declaration of Principles on Academic Freedom and Tenure, which affirmed the scholar’s primary duty to seek and establish truth. Though its roots lie in Germany, academic freedom ultimately became a cornerstone of American academic discourse.

    In the United States, academic freedom draws from multiple sources, with its protection varying by state laws, customs, institutional practices, and the status of higher education institutions. However, U.S. Supreme Court rulings have gradually reinforced its constitutional foundation, particularly after the McCarthy era, by invoking the First Amendment. Landmark cases such as Adler v. Board of Education (1952), Wieman v. Updegraff (1952), and Sweezy v. New Hampshire (1957) helped establish a constitutional doctrine on academic freedom. Finally, Keyishian v. Board of Regents (1967) extended First Amendment protections to academia, ruling that mandatory loyalty oaths violated both academic freedom and freedom of association.

    Interestingly, the American interpretation of academic freedom is currently more restrictive than the German model in certain respects. Article 5(3) of the 1989 Basic Law affirms the “right to adopt public organizational measures essential to protect a space of freedom, fostering independent scientific activity”. In contrast, the U.S. places greater emphasis on prohibitions and prioritizing individual rights over institutional autonomy.

    The ‘right to be wrong’

    Despite local variations, academic freedom is fundamentally tied to a shared vision of the university that upholds freedom of thought, with rationality and pluralism at its core. It includes the genuine “right to be wrong”–the understanding that a scientific opinion may be incorrect or even proven so does not diminish its protection. This stands in stark contrast to the anti-science, scientistic, or techno-nationalist approach, which views knowledge as a tool of power to serve a predetermined truth and objective of dominance. Authoritarian science, driven by power interests, seeks to diminish critical humanities and social sciences while elevating religion. It tends to reject interdisciplinary work, is exclusively mathematized, and is oriented toward a centralized yet deregulated autocratic tech-utopian state model.

    Since 1945, we have operated under the illusion that academic freedom is an indispensable condition for scientific excellence. However, we have recently learned that no systematic link exists between academic freedom and breakthrough scientific innovation in our era of new technologies. Given these circumstances, this proposal advocates for a nomination for the Nobel Peace Prize, for the first time in its history, in recognition of academic freedom.

    The Nobel Prize Committees for Science and Peace share the responsibility of using their prestigious platforms to uphold fundamental scientific and democratic values. They are uniquely positioned to champion humanist science, reinforcing its importance for scholars, students, and civil societies worldwide. Since the 1950s, around 90% of Nobel Prize laureates in scientific fields have either been US citizens or have studied and worked at Ivy League research institutions.

    While some US scientists are contesting actions of the Trump administration in court, academics worldwide should stand in solidarity with their American colleagues in resisting the erosion of science. To strengthen their efforts, they require the support of the Nobel Prize Committees.

    MIL OSI Europe News –

    March 7, 2025
  • MIL-OSI United Kingdom: New evidence reveals that all Londoners are now breathing cleaner air following the first year of the expanded Ultra Low Emission Zone (ULEZ)

    Source: Mayor of London

    1. Roadside Nitrogen Dioxide (NO2) levels, a toxic gas that exacerbates asthma, impedes lung development, and raises the risk of lung cancer, have decreased by a record 27% across the entire capital [1].
    2. Particle emissions (PM 2.5) from vehicle exhausts, are 31% lower in outer London in 2024 than they would have been without the ULEZ expansion. [2]
    3. The environmental impact of ULEZ has been substantial, with carbon emissions equivalent to nearly three million one-way passenger trips between Heathrow and New York saved [3]
    4. Air quality has improved at 99% of air quality monitoring sites across London since 2019, and London’s air quality is improving at a faster rate than the rest of England [4, 5]

    In London, around 4,000 premature deaths per year were previously attributed to toxic air [6]. Air pollution increases the risk of developing asthma, lung cancer, heart disease and stroke, and there is growing evidence that air pollution exposure increases the risk of developing dementia [7]. 

    In April 2019, the Mayor of London launched the world’s first 24-hour Ultra Low Emission Zone (ULEZ) in central London. The zone was expanded across inner London in 2021, and finally to cover the whole capital In August 2023, bringing the air quality and associated health benefits to the five million people living in outer London.

    A new City Hall report, extensively reviewed by an independent advisory group of experts* shows that the ULEZ has led to substantial improvements in air quality in outer London and across the capital. [1]

    Particle emissions (PM2.5) from vehicle exhausts are estimated to be 31% lower in outer London in 2024 than they would have been without the ULEZ expansion. Alongside NO2 and PM2.5 reductions, NOx (Nitrogen Oxides) emissions from cars and vans are also estimated to be 14 per cent lower in outer London. [2]

    The biggest reductions in NO2 levels have been in central London (54%) but there have also been substantial reductions in inner London (29%) and outer London (24%) [1].

    The boroughs that have seen the biggest reductions in NOx emissions due to the ULEZ expansion are Sutton, Merton, Croydon, Harrow and Bromley, where harmful emissions are estimated to be around 15 per cent lower in 2024 than would be expected without the expansion to outer London, which covers a large area of around 1250km2.

    Thanks to all phases of the ULEZ, NOx emissions from road transport are estimated to be 36 per cent lower across London in 2024, a saving of around 3400 tonnes – the equivalent of approximately one year of emissions from all passenger car trips in Los Angeles [8]. 

    The report also shows that the ULEZ has led to savings in carbon emissions.

    Cumulatively between 2019 and 2024, the equivalent of nearly three million one-way passenger trips between Heathrow and New York has been saved in carbon due to ULEZ as a whole [3]. 

    Deprived communities are seeing some of the biggest benefits. For some of the most deprived communities living near London’s busiest roads, there was an estimated 80 per cent reduction in people exposed to illegal levels of pollution in 2023 – this increases to 82 per cent in outer London, compared to a scenario without the ULEZ [9]. 

    Data from the report [2], alongside independent analysis [10] has found that the ULEZ expansion has not impacted footfall or retail and leisure spending in either outer London or London as a whole [8]. Visitor footfall in outer London increased by almost 2 per cent in the year after the London-wide ULEZ expansion.

    The Mayor of London, Sadiq Khan, said: “When I was first elected, evidence showed it would take 193 years to bring London’s air pollution within legal limits if the current efforts continued. However, due to our transformative policies we are now close to achieving it this year. Today’s report shows that ULEZ works, driving down levels of pollution, taking old polluting cars off our roads and bringing cleaner air to millions more Londoners. 

    “The decision to expand the ULEZ was not something I took lightly, but this report shows it was the right one for the health of all Londoners. It has been crucial to protect the health of Londoners, support children’s lung growth, and reduce the risk of people developing asthma, lung cancer and a host of other health issues related to air pollution.   

    “With boroughs in outer London seeing some of the biggest reductions in harmful emissions and London’s deprived communities also seeing greater benefits, this report shows why expanding ULEZ London-wide was so important. 

    “Thanks to ULEZ and our other policies, all Londoners are now breathing substantially cleaner air – but there is still more to do, and I promise to keep taking action as we build a greener, fairer London for everyone.”    

    TfL data also shows that Londoners have continued to upgrade their vehicles to cleaner models with 96.7 per cent of vehicles seen driving in London now ULEZ compliant, up from 91.6 per cent in June 2023 and 39 per cent in February 2017, when changes associated with the ULEZ began. Van compliance in outer London is over 90 per cent for the first time (90.7 per cent). In February 2017, just 12 per cent of vans met the ULEZ standards, demonstrating the schemes’ impact on reducing the number of more polluting older vans driving in London. [2]

    The data also shows there were nearly 100,000 fewer non-compliant vehicles detected in London on an average day in September 2024 compared to June 2023, when the Mayor announced his plans to extend the ULEZ to outer London – a 58 per cent reduction in non-compliant vehicles. This has been aided by the Mayor’s scrappage scheme, which provided around £200m to support Londoners to switch to cleaner vehicles. The scrappage schemes that supported the introduction of the ULEZ to central London, and the expansion to inner London, were successful in removing 15,232 older and more polluting vehicles from London’s roads. Over 54,700 further applications were approved before the scheme closed in September 2024, including over 400 vehicles donated to humanitarian and medical efforts in Ukraine. A ULEZ scrappage scheme evaluation report to be published shortly will set out the full impact of the scheme, including the total numbers of vehicles scrapped, replaced and donated. 

    The ULEZ is the centrepiece of a range of measures the Mayor and TfL is implementing to tackle London’s toxic air, including putting a record number of 1900 zero-emission buses on the roads. Since 2019, air quality has improved in 99 per cent of air quality monitoring sites included in the analysis (8) across London, thanks to these measures and wider transport policies, with 80 per cent of monitoring locations showing average NO2 concentration reductions of more than 10 µg/m3, which is a quarter of the legally permitted annual NO2 concentration.   

    London’s air quality is improving at a faster rate compared to the rest of England (2017-2024). This is particularly notable in outer London where concentrations have improved more rapidly over recent years and are now similar to the rest of England average, which has historically been lower than London [9].  

    Dr Maria Neira, Director, Department of Environment, Climate Change and Health at the World Health Organization: “Improving air quality through initiatives like the Ultra Low Emission Zone in London is crucial for protecting public health and reducing the burden of disease. Cleaner air leads to healthier communities, lower rates of respiratory and cardiovascular illnesses, and a better quality of life for all residents. The World Health Organization commends the efforts of cities like London in implementing measures to reduce emissions from vehicles and improve air quality, which ultimately contribute to a healthier and more sustainable urban environment.”

    Anne Hidalgo, Mayor of Paris, said: “Reducing car traffic is one of our greatest opportunities to address the climate emergency. Under the leadership of Mayor Khan, London is showing us what safer, healthier, and greener communities look like, and the results of London’s clean air zone speaks for itself. I commend Mayor Khan for his commitment, leadership and vision to addressing the climate crisis and protecting the lives and health of city residents. London is demonstrating once again that cities lead the fight against climate change.”

    Rosamund Adoo-Kissi-Debrah CBE, Global Heath Advocate and Founder of the Ella Roberta Foundation said: “I am delighted that the latest analysis since the expansion of ULEZ to outer London shows that air pollution has reduced.  My daughter Ella died from emissions from the South Circular Road close to where we live, and I will not stop until everyone in London can breathe safe, clean air, regardless of where they live in the city.  People’s health, particularly children’s, should always be prioritised by society, and I look forward to hearing what further plans the Mayor has to continue to clean up the air for all Londoners.  ULEZ was an important step, but there is so much more to do, and I will ensure that politicians and decision-makers are held to account, and do all they can to protect people’s health and clean up the air we breathe.”

    Christina Calderato, TfL’s Director of Strategy, said: “Bold and ambitious environmental schemes like the ULEZ are pivotal to making tangible long-term air quality improvements to tackle a public health crisis, as shown in this new report. Everyone in the capital is now breathing cleaner air because of ULEZ. Harmful NO2 concentrations are 27 per cent lower across the city than if there had been no ULEZ. There’s less PM2.5 exhaust emissions and NOx pollutants from cars and vans in outer London – an even greater reduction than reported in the first six months of ULEZ showing the continued success of the scheme.  

    “It is great to see it making a real difference to the air Londoners breathe, and together with our efforts to decarbonise the public transport network, will see generations to come reaping the benefits of a greener, cleaner London.” 

    Dr Gary Fuller, Imperial College London, and Chair of the ULEZ Advisory Group, said: “Each phase of the ULEZ has led to clear improvements in the air pollution next to London’s roads. This is good news for the current and future health of Londoners, as well as those who travel to London for work or leisure.   

    “The analysis in this report benefited from an international advisory group of scientists, all with experience in assessing the impacts of urban clean air policies. We worked with the Mayor’s team to stress-test key parts of the analysis and concluded that the core methodology used in this report, and in previous ULEZ reports, was appropriate and robust. The ULEZ is one of over 300 such schemes across the UK and Europe, and many cities are looking to London’s ULEZ results to inform their own plan.”

    Jemima Hartshorn, Director, Mums for Lungs said: “Today is a good day for children, and all of us: Air pollution has been reduced due to the pioneering measures of our Mayor and we are so glad about that. But air pollution across the country and even London remains too high. Hopefully, the national Government will learn from this success and support Mayors and councils in stopping pollution from diesel and wood burning making us sick.”

    Larissa Lockwood, Director of Policy and Campaigns at Global Action Plan said: “Clean air is a health and social justice issue. This report shows that bold, pro-environment policies can be successful – both in terms of health benefits and electoral success. We celebrate the air quality improvements from ULEZ, urge the Mayor to continue cleaning up the air in London and hope that other political leaders across the UK and the world will be inspired to implement bold measures to tackle air pollution.”

    Izzy Romilly, Sustainable Transport Manager at Possible said: “The largest clean air zone in the world has been a triumph. We’ve slashed pollution, and we’ve protected the lungs of the most vulnerable Londoners, with the biggest benefits being felt in areas of highest deprivation. Now, national government and leaders around the world should learn the lessons of ULEZ and show the same ambition to clean up toxic air. Here in London, these findings should give the Mayor the courage to go further and faster on tackling harmful emissions. We need to see more action on transport and traffic, a serious tax on SUVs, and a diesel phase out by 2030.”

    Jane Burston, CEO at Clean Air Fund said: “The new data shows how the ULEZ is making a real difference to the quality of the air Londoners breathe. It’s especially encouraging to see that the communities living near the busiest roads are seeing substantial benefits one year on. London’s progress provides an inspiring blueprint for others, including those in our Breathe Cities initiative, by showing how tackling air pollution can improve lives, boost public health and address the climate crisis.”

    Barbara Stoll, Senior Director at Clean Cities Campaign said: “Despite fierce opposition – even from the government of the time – the Mayor stood firm, and the results speak for themselves. The ULEZ shows that when city leaders have vision and determination, they can reduce inequities and transform urban life for the better. We urge the Mayor to continue his leadership in championing healthy, climate-friendly transport and to stay committed to making London the world’s first truly electric-vehicle-ready global city.”

    Michael Solomon Williams from Campaign for Better Transport said: “This report shows that clean air zones work and other cities should take encouragement from London’s experience. Reducing the harmful effects of road transport and ensuring there are good public transport, walking and cycling options are key to creating healthier, happier communities.”

    Livi Elsmore, Campaign Manager, Healthy Air Coalition said: “Over a year on from the expansion of the Ultra Low Emission Zone (ULEZ) in London, we are delighted to see significant progress made in cleaning up the capital’s air to protect the health of everyone who lives and works in the capital, and future generations of Londoners.

    “Contributing to as many as 4,000 deaths each year in London, air pollution poses the greatest environmental threat to our health. Measures like the ULEZ are among the most effective tools we have to tackle toxic air and protect public health.

    “And the impact of ULEZ is now clear: toxic nitrogen dioxide emissions are 27% lower than they would be without the scheme.

    “We call on the Mayor of London to continue showing leadership through building a pathway for London to meet the air pollution levels recommended by the WHO, meet London’s transport targets, and take concerted action on unnecessary wood burning in the capital.”

    Henry Gregg, Director of External Affairs, Asthma + Lung UK said: “A year on it’s great to see the ULEZ expansion is having a positive impact on improving the capital’s air quality and helping protect the lung health of millions of people, every day. Expanding ULEZ reduced the number of polluting vehicles on the road and is helping every Londoner, regardless of age, ethnicity or background, breathe cleaner air. Air pollution is a public health emergency that affects us all – particularly the estimated 585,000 people in Greater London who have asthma or Chronic Obstructive Pulmonary Disease (COPD). Air pollution can worsen the symptoms of people with existing lung conditions, such as breathlessness, wheezing and coughing, and potentially lead to life-threating asthma attacks or serious flare-ups. In some cases it can lead to hospitalisation and even death – up to 4,000 early deaths a year in the capital are linked to air pollution. Unfairly, it is often those living in the most deprived communities who are affected the most by breathing in toxic air. There are no safe levels of air pollution and the government must commit to an ambitious Clean Air Act, which could protect people, wherever they live, from the dangers of polluted air.”

    Yvonne Aki-Sawyerr OBE, Mayor of Freetown and Co-Chair of C40 Cities: “Clean air is not a privilege, it’s a fundamental right. The success of London’s clean air zone serves as a powerful testament to the impact of bold action in protecting public health, especially for our most vulnerable communities. As his fellow Co-Chair of C40 Cities, I am proud to stand alongside him, and I urge leaders everywhere to take note of these transformative policies.”

    Giuseppe Sala, Mayor of Milan: “The impact of London’s clean air zone is clear: better air, fewer emissions, and a healthier future for all Londoners. Milan supports and celebrates this achievement, as we work on similar policies to protect the health of our residents and make our cities greener and more liveable for all.” 

    Martin Lutz, formerly Berlin City Government, and member of the ULEZ Advisory Group, said: “With the latest step of extending the ULEZ to the whole city, London has set a global benchmark for how access restrictions for high emission vehicles can effectively reduce air pollution from cars.    

    “This one year report makes a very strong case for the success and health benefits of the ULEZ for Londoners, thanks to the wealth of data and measurements that have been painstakingly collected over the years of the zone’s gradual expansion.”   

    Ludo Vandenthoren, Mutualités Libres (a Belgian mutual health insurance firm), and member of the ULEZ Advisory Group, said: “It was an honour to work on this project alongside experts in the field. The GLA and TfL, with their commitment to the citizens of London, demonstrated great receptiveness to the feedback we provided. We were able to contribute information on the socio-economic aspects and health effects of air quality, offer input on the statistical methodology specific to this topic, and share valuable references for their reports. I am particularly proud that the study from the Belgian Independent Health Insurance Funds on air quality is seen as an inspiring model for their own approach. The London ULEZ is an ambitious initiative that will undoubtedly inspire other cities.”  

    Professor David Carslaw, University of York, and member of the ULEZ Advisory Group, said: “This report represents a detailed evaluation of the emissions and air quality impacts of the London ULEZ. London and its surrounding areas are fortunate in having one of the world’s most comprehensive air quality networks, which provides a strong basis for the evaluation of the air quality impacts of the ULEZ as it has expanded in recent years. The results show the benefits of the ULEZ are widely distributed and have accelerated the improvement in London’s air quality.”  

    Dr Chinthika Piyasena, Consultant Neonatologist in London said: “As a Londoner and clinician, I’ve long advocated for bold action on air pollution because the science is clear: toxic air harms babies before they even take their first breath. Nitrogen dioxide exposure has been linked to an increased risk of stillbirth, babies being born too early or too small, and even impacts brain development. So a year after the full expansion of ULEZ, it’s incredible to see real progress in reducing this pollutant. Every step we take towards cleaner air, is a step toward healthier pregnancies, healthier babies and a healthier future for all Londoners.”   

    Simon Birkett, Founder and Director of Clean Air in London said: “I have campaigned for low emission zones since April 2006 – almost two years before the first phase was implemented in London. I was also the first to call for an inner London low emission zone. It is particularly pleasing therefore that the Mayor’s One-Year report on ULEZ expansion – the ninth phase of low and ultra-low emission zones in London – has shown again that these big solutions work. In fact, together with related measures such as cleaner buses and taxis, they have almost single handedly helped London to slash nitrogen dioxide (“NO2”) concentrations by 2/3 near busy roads, and nearly comply with legal limits and the WHO’s 2005 air quality guideline of 40 micrograms per cubic metre (“mg/m3”) by 2025, probably ahead of smaller UK cities.” 

    Professor Kevin Fenton, London Regional Director, Office for Health Improvement and Disparities and Regional Director of Public Health, NHS London said: “As well as reducing air pollution in outer London, this report also shows that ULEZ and its expansions continue to have a positive impact on air quality across the city. Londoners are now benefiting from improved air quality, and this is particularly true for those communities who live in more deprived areas of London.  

    “In a city where over 480,000 Londoners have a diagnosis of asthma and are more vulnerable to the impacts of air pollution, a 27% reduction in harmful roadside NO2 concentrations across the whole city will bring about invaluable health benefits. And I’m optimistic that Londoners will continue to benefit from better air quality, and subsequently, better health, due to the ULEZ and its expansions.”

    Chris Streather, Medical Director and Chief Clinical Information Officer, NHS England London, said: “It’s encouraging to see that all Londoners have experienced a significant improvement in air quality, and this reduction in pollutants directly contributes to better health outcomes.

    “Vital initiatives like the ULEZ create a healthier urban environment, reducing the risks of respiratory conditions such as asthma and lung cancer, and ultimately lessen the burden on our health system.”

    MIL OSI United Kingdom –

    March 7, 2025
  • MIL-OSI: Alliance Witan PLC – Final Results

    Source: GlobeNewswire (MIL-OSI)

    Alliance Witan PLC (‘the Company’)
    LEI: 213800SZZD4E2IOZ9W55

    7 March 2025

    A landmark year

    Annual results for the year ended 31 December 2024

    Highlights

    • 2024 was a landmark year for the Company, which was promoted to the FTSE 100 after the combination with Witan Investment Trust Plc (‘Witan’).
    • The Company’s share price was 1,244 pence (£12.44) as of 31 December 2024, representing a Share Price Total Return1 of 14.3%.
    • The Company’s Net Asset Value Total Return1 of 13.3%, while strongly positive, trailed our benchmark index, the MSCI All Country World Index (‘MSCI ACWI’), which returned 19.6%.
    • The Company’s average discount narrowed to 4.7% from 5.4% at the end of 2023, which compared favourably with the average discount for the Association of Investment Company’s Global Sector of 7.9%.
    • A fourth interim dividend 6.73p per share was declared on 28 January 2025, bringing the total dividend for the year ended 31 December 2024 to 26.70p per share. This is a 6% increase on the previous year, the 58th consecutive annual increase.

    Dean Buckley, Chair of Alliance Witan, commented:

    “The Company delivered strong outright gains for shareholders in 2024, although in common with most active global equity strategies, we underperformed our benchmark index, MSCI ACWI, where performance was concentrated in a handful of the largest US companies. Even so, the Company’s longer-term performance remains competitive, and demand for our shares was healthy last year, with the Company’s discount narrowing, bucking the industry trend towards widening discounts. We also increased our dividend for the 58th consecutive year.

    “Thanks to the support of both sets of shareholders, we achieved a historic combination with Witan, which places the Company in a strong position to realise economies of scale and offer better liquidity for our shares. With solid performance and a refreshed brand, supported by a marketing campaign that will continue in 2025, the Board is confident that the Company is well placed to continue delivering attractive returns for shareholders”.

    About Alliance Witan PLC

    Alliance Witan aims to be a core investment that beats inflation over the long term through a combination of capital growth and rising dividend. The Company invests in global equities across a wide range of different sectors and industries to achieve its objective. Alliance Witan’s portfolio uses a distinctive multi-manager approach. We blend the top stock selections of some of the world’s best active managers into a single diversified portfolio designed to outperform the market while carefully managing risk. Alliance Witan is an AIC Dividend Hero with 58 consecutive years of rising dividends.

    https://www.alliancewitan.com

    For more information, please contact:

    For more information, please contact:
    Mark Atkinson
    Senior Director
    Client Management, Wealth & Retail
      Sarah Gibbons-Cook
    Director
    Willis Towers Watson   Quill PR
    Tel: 07918 724303   Tel: 07702 412680
    mark.atkinson@wtwco.com   AllianceWitan@quillpr.com

    1. Alternative Performance Measure. Share Price Total Return is the return to shareholders through share price capital returns and dividends paid by the Company and re-invested. Net Asset Value (NAV) Total Return is a measure of the performance of the Company’s NAV over a specified time period. It combines any change in the NAV and dividends paid.

    Financial highlights as at 31 December 2024

    Net Assets Net Asset Value (‘NAV’) per Share
    £5.2bn 1,304.9p
    (2023: £3.3bn) (2023: 1,175.1p)
       
    NAV Total Return1 Share Price
    +13.3% 1,244.0p
    (2023: +21.6%) (2023: 1,112.0p)
       
    Share Price Total Return1 Discount to NAV1
    +14.3% -4.7%
    (2023: +20.2%) (2023: -5.4%)
       
    Earnings per Share (Revenue) Total Dividend per Share
    17.3p 26.7p
    (2023: 18.6p) (2023: 25.2p)

    1. Alternative Performance Measure – see page 116 of the Annual Report for further information.
    Notes:
    NAV per Share including income with debt at fair value.
    NAV Total Return based on NAV including income with debt at fair value and after all costs.
    Source: Morningstar and Juniper Partners Limited (‘Juniper’).

    Chair’s Statement

    • Landmark combination with Witan
    • Another strong year for equities
    • 58th consecutive annual dividend increase
    • Discount narrower than the AIC Global Sector average
    • Named by the AIC as a top 20 best performing investment trust over ten years1

    2024 was a landmark year for your Company. I would like to begin by thanking you for your support for the combination of Alliance Trust and Witan to form Alliance Witan and by welcoming all shareholders who have joined us as a result. This was a pivotal moment in our history, achieving economies of scale and elevating the Company to the FTSE 100. Now, as one of the industry’s leaders, this status will provide better liquidity for our shares and, with good long term investment performance and a strong brand, help us attract new investors. We made a number of commitments to investors as part of the proposals, for example in respect of dividends and costs, and you will see as you read through the Annual Report how we have achieved each of these.

    As I mentioned in the Interim Report for the six months ended 30 June 2024, there has been no change to the Company’s investment strategy, just a larger pool of assets for our Investment Manager, WTW, to manage with the same professionalism that it has brought to the job since April 2017.

    1. https://www.theaic.co.uk/aic/news/press-releases/top-20-best-performing-investment-trusts-for-your-isa

    Investment Performance

    It was another good year for global equity markets, and your Company delivered strong absolute returns. NAV Total Return was 13.3% and, due to a narrowing of the discount, Share Price Total Return was 14.3%. However, we lagged our benchmark index, the MSCI All Country World Index (‘MSCI ACWI’ or ‘Index’), which returned 19.6%. We also marginally underperformed our peers in the AIC Global Sector, which is disappointing, but we were slightly ahead of the much wider, more representative Morningstar peer group of open and closed-ended global equity funds.

    Simply put, our relative performance in 2024 suffered from not having enough exposure to the small number of very large companies that dominated market returns, especially in the US.

    The narrowness of returns from global equity markets has been a common problem for all active managers in recent years, and we take comfort from the fact that, despite this persistent headwind, we are ahead of the Index and have significantly outperformed both peer groups over three years. You can read more about the contributors/detractors to the Company’s investment performance during 2024 in the Investment Manager’s Report on page 9 of the Annual Report.

    Dividend increased for the 58thconsecutive year

    The Board declared a fourth interim dividend of 6.73p per share on 28 January 2025, resulting in a full year dividend of 26.70p, an increase of 6.0% on the prior year. This fulfils the promise we made at the time of the combination of Alliance Trust and Witan to increase dividends for the legacy shareholders of both companies. 2024’s increase marks the 58th consecutive annual increase, which is one of the longest track records in the investment trust industry. Dividends are well supported by revenue and reserves, and the Board is confident annual dividend increases can continue well into the future. Due to our steady approach, the Company has received a ‘Dividend Hero’ investment company award from the Association of Investment Companies (‘AIC’).

    Narrowing discount

    Many investment trusts continued to trade on large discounts to NAV throughout 2024, with the industry average widening to 14.7% from 12.7%.1 I am pleased to report that your Company fared better than most, with its average discount falling to 4.7% from 5.4% over the year. This compared favourably with the average discount for the AIC Global Sector of 7.9%.

    Your Board remains committed to the maintenance of a stable discount. We will continue to use share buybacks as appropriate and invest in promotional activity to widen our shareholder base, to support the management of the discount. During 2024, the Company bought back 4.7 million shares (1.2% of shares in issue2), versus 8.6 million repurchased in 2023. The shares bought back during the year were placed in Treasury. This level of buybacks was significantly below that of our peers, in a year in which industry-wide buybacks hit a record level of £7.5 billion3. The shares held in Treasury can be reissued by the Company at a premium to estimated NAV when there is market demand.

    Board changes

    Following the completion of the combination of Alliance Trust with Witan, we welcomed four new Non-Executive Directors to the Board: Andrew Ross, Rachel Beagles, Shauna Bevan and Jack Perry, all of whom were former directors of Witan.

    Clare Dobie, having served for almost nine years, is retiring as a Director at the conclusion of this year’s Annual General Meeting (‘AGM’), as is Jack Perry, reducing the size of the Board to eight members.

    On behalf of the Board, I would like to thank Clare and Jack for their contributions.

    Annual General Meeting

    The Board looks forward to being able to meet shareholders again at this year’s AGM, which will be held at the Apex City Quay Hotel in Dundee on 1 May 2025. For those shareholders who are not able to attend in person, we will be live streaming the event. As well as the formal business of the meeting, there will be an investor forum afterwards featuring two of our Stock Pickers, Jennison and EdgePoint, as well as members of WTW’s investment team. There will be another in-person investor forum in London in the autumn. In addition, shareholders can engage with the Company and its Stock Pickers via online presentations during the year. Further details of how to attend all these events can be found on the website.

    The Board would strongly encourage shareholders to use the opportunity to have their say and use their vote at the AGM. Further information on the arrangements for the AGM, including information on how to vote either directly through the Registrar or though different platforms, is on pages 134 and 135 of the Annual Report.

    Keep up-to-date

    In these unusual times, the website will provide timely updates to shareholders. Therefore, I would encourage you to visit the website which contains a vast amount of information on investment performance, details of shareholder meetings and investor forums, monthly factsheets, quarterly newsletters, and Stock Picker updates, as well as the Annual and Interim Reports.

    As always, the Board welcomes communication from shareholders and I can be contacted through Juniper Partners (‘Juniper’), the Company Secretary at investor@alliancewitan.com.

    Outlook

    Since the start of President Trump’s second term of office in January, tariffs have created uncertainty about the outlook for equities. Diplomatic tensions over efforts to end the war in Ukraine and conflict in Gaza have also raised geopolitical risks. Furthermore, European bond markets are adjusting to the prospect of increased borrowing to fund higher levels of defence and infrastructure spending.

    While there is a risk that heightened levels of uncertainty will impact on business and consumer confidence, global growth and corporate earnings forecasts are currently healthy, giving some grounds for cautious optimism, about further gains for shareholders, especially if there is a broadening out of market leadership.

    While the Index is highly concentrated, your portfolio has broader exposure to many good businesses that have not yet received the market recognition our Stock Pickers believe they deserve.

    The portfolio will not always outperform the market in every discrete period, but we believe it will continue to add significant value for shareholders in the long run.

    I look forward to meeting as many of you as possible at the AGM in Dundee or the next investor forum in London.

    1. Weighted average discount (excluding 3i Group). Source: Winterflood.
    2. Percentage based on the Company’s issued share capital (excluding shares held in Treasury) as at 1 January 2025.
    3. Source: AIC and Morningstar.

    Dean Buckley
    Chair
    6 March 2025

    Combination with Witan

    The most significant development during the year under review was the combination of the Company with Witan.

    Background

    Following a comprehensive review of management arrangements, the Witan Board concluded that a combination with the Company was in the best interests of Witan’s shareholders. Amongst other things this allowed them continued exposure to a successful multi-manager approach.

    The combination was undertaken by way of a scheme of reconstruction and members’ voluntary liquidation of Witan. The scheme required the approval of both the Company and Witan’s shareholders and took effect on 10 October 2024. It resulted in the Company acquiring approximately £1,539 million of net assets from Witan in consideration for the issue of new ordinary shares to Witan shareholders. The name of the Company became Alliance Witan and the stock exchange ticker ALW.

    Outcome

    The combination was expected to result in substantial benefits for all shareholders and future investors. The outcomes of the key elements of the proposals include:

    • Greater profile and FTSE 100 inclusion: the Company has assets of over £5 billion and is now a FTSE 100 Index constituent.
    • Lower management fees: WTW agreed a new management fee structure; this resulted in an even more competitive blended fee rate for all shareholders.
    • Lower ongoing charges: the new management fee structure and economies of scale have reduced ongoing charges to 0.56% (net of the management fee waiver).
    • No cost to either companies’ shareholders: the costs of the transaction were carefully managed, including the fee waiver from WTW, to ensure that the transaction was completed at no cost to all shareholders.
    • Attractive and progressive dividend policy: the third and fourth interim dividend payments of 2024 were increased to ensure that they were commensurate with Witan’s first interim dividend. It is expected that the dividend will continue to increase in the current year so that shareholders continue to see progression in their income.

    Portfolio Transition

    • The Company received assets including cash and equities from Witan and the Witan loan notes were novated to the Company. Details are provided in note 13 to the Financial Statements.
    • BlackRock Investment Management (UK) Limited managed the portfolio transition. Direct costs of the portfolio transition and Manager changes were less than 0.04% of the Net Asset Value of the enlarged portfolio.

    Investment Manager’s Report

    Market backdrop: equities untroubled by politics

    For the second year running, global equities delivered strong returns in 2024, with economics trumping politics. Despite a record number of elections, conflicts in the Middle East and Ukraine reaching new heights, and a scary moment in Japan when the Nikkei Index of the top 225 blue-chip shares plunged 12% in a day at the beginning of August, investors focused on resilient global growth, falling inflation and interest rates, and healthy corporate profitability.

    Hence, our benchmark index, the MSCI ACWI, returned 19.6% in 2024 following a return of 15.3% in 2023. Since 1987, the Index has returned an average of 8.4% per annum1, so returns of this magnitude in two consecutive years are rare. The ebullient mood of equity investors was reflected in a surge in the prices of less established assets, such as cryptocurrency, with Bitcoin reaching all-time highs of over $100,000. Peanut the Squirrel Coin, a cryptocurrency named after the eponymous pet that New York environmental authorities seized and euthanised on 30 October 2024, at one point commanded a market cap of $1.7 billion.

    However, regional equity market performance was mixed. US markets once again led the way, with the S&P 500 delivering a 27% return when measured in British pounds. Chinese equities rallied briefly following government stimulus, but concerns over the country’s property market and trade tensions persisted. Together with a strong US dollar, these worries led to more subdued returns from emerging markets, which rose about 9%. In Japan, August’s technically driven decline proved temporary, and the Nikkei resumed its ascent to close the year at a record high, although the yen’s depreciation reduced returns for UK-based investors when converted into British pounds. The UK and European markets were more muted, with the FTSE All Share Index and the MSCI Europe ex UK Index returning 9.5% and 1.9% respectively.

    Gains driven by US tech giants

    Giant US technology related stocks were the standout performers, fuelled by investor excitement about generative artificial intelligence (‘AI’) and, from November onwards, hopes that Donald Trump’s victory in the presidential election would weaken regulatory scrutiny. The share prices of the so called “Magnificent Seven” – Apple, Amazon, Alphabet, Meta, Microsoft, NVIDIA and Tesla – increased by 60% on average and were responsible for 43% of MSCI ACWI’s gains. This was less than 2023 when they contributed 53%, but still a huge number emphasising the extreme concentration of index returns in a small number of companies.

    Even so, from mid-year onwards, returns were no longer quite as skewed to the performance of a handful of shares. Although NVIDIA and Tesla returned a massive 176% and 65% respectively, giant tech was not the only game in town. Financial stocks returned 26.5%, and returns from the consumer discretionary, industrial and utility sectors were also well into double figures, pointing to the potential broadening out of market returns as stock-specific drivers came to the fore.

    1. https://www.msci.com/documents/10199/8d97d244-4685-4200-a24c-3e2942e3adeb

    Portfolio performance: strong absolute gains but lagged benchmark index

    Our portfolio’s NAV Total Return was a robust 13.3% but, as with most active managers, it lagged the Company’s benchmark index. The portfolio does, however, remain ahead of the Index over three years (28.0% vs 26.8%), albeit behind over five years (64.7% vs 70.8%). Disappointing though it was not to beat the MSCI ACWI in 2024, we were not alone. AJ Bell calculated that, to the end of November, just 18% of active global equity funds outperformed their passive peers, largely due to their inability to match high Index weightings in the “Magnificent Seven”. The sheer size of these companies in the Index is mind boggling. NVIDIA, Microsoft and Apple, for example, represent 13% of the MSCI ACWI as at 31 December 2024 and, together, are bigger than the entire stock markets of several sizeable countries.

    The skew of the Index towards mega-cap companies has been a challenge, to varying degrees, since the start of our multi-manager strategy in April 2017. As a broadly diversified strategy, with capital spread between 8-12 Managers, all with different approaches to investing, our portfolio naturally has a structural bias away from stocks that on rare occasions represent such a large proportion of our global benchmark. While we have some exposure to most of the “Magnificent Seven”, it would require a lot of the Managers to choose them as one of their best ideas for us to be at Index weight, never mind be overweight.

    The Index may have been hard to beat in recent years, but market concentration poses significant risks for passive strategies. At the end of 2024, the Index on average allocated around 150 times as much capital to each of Apple, NVIDIA and Microsoft as it did to the average stock, akin to us placing about 95% of the portfolio in one manager’s hands and 0.5% each in the other ten.

    We do not believe this is the right way to manage risk for shareholders, bearing in mind that index trackers are not investing lots of money in these companies because they are good businesses trading at good valuations, but because they are very big. If US large-cap stocks continue to dominate, tracker funds may continue to outperform active funds. But if sentiment on the technology sector turns sour, passive funds with big stakes will be hit much harder.

    Not owning enough NVIDIA was painful

    The strong outperformance of our portfolio versus our benchmark in 2023 continued into the first quarter of 2024, when the biggest contribution came from not owning, at that time, poorly performing Tesla and Apple. But thereafter stock selection became more challenging, particularly within the “Magnificent Seven”. Although we benefitted from owning Amazon and Microsoft, we moved from an overweight to an underweight position in NVIDIA in the first quarter after its extraordinary outperformance, which then made it our biggest single detractor last year as that outperformance continued. Having helped us in the first quarter, the lack of exposure to Tesla and Apple, which both recovered strongly as the year progressed, counted against us from then on. Overall, our positions in the “Magnificent Seven” accounted for a third of the portfolio’s underperformance versus the Index in 2024.

    The remainder of the portfolio’s underperformance came from a combination of being underweight in large-cap stocks in general and stock specific issues elsewhere, in some cases due to partial reversals of performance in 2023. For example, stock selection in financials detracted in large part due to our relative lack of exposure to strongly performing US banks such as JP Morgan and Goldman Sachs. In the consumer discretionary sector, the share price of UK-based drinks company Diageo, owned by Veritas Asset Management (‘Veritas’) and Metropolis Capital (‘Metropolis’), continued to suffer from a post-Covid cyclical downturn, falling 8.5%, although both Managers believe the company will eventually recover lost ground when structural trends reassert themselves. Novo Nordisk, the Danish weight loss drugs company, was another notable detractor, as its shares fell 14% after disappointing test results. Our Stock Pickers see this as a temporary decline in a growing market in which Novo Nordisk has a leading position. Hence, it was one of our biggest purchases in 2024 (see table below).

    Indeed, our Stock Pickers express a high degree of confidence in the latent value of many of their holdings. By far the most important long run ingredient underpinning share price performance is strong fundamentals, such as market-leading products or services, solid profit margins, plentiful cashflow and strong management.

    Top 10 purchases and sales

    Top 10 purchases Value £m   Top 10 sales Value £m
    UnitedHealth Group 50.2   Alphabet 84.3
    Novo Nordisk 48.8   NVIDIA 71.3
    Synopsys 47.5   Fiserv 39.0
    Microsoft 45.0   Aena 37.9
    Netflix 41.5   Ebara 36.1
    Philip Morris 41.4   TotalEnergies 35.0
    Enbridge 39.4   PayPal 33.8
    AT&T 39.0   Bureau Veritas 33.4
    American Electric Power 37.3   KKR 33.2
    Eli Lilly 36.6   Taiwan Semiconductor 32.2

    Source: Juniper.
    The purchases and sales are calculated by taking the net value of all transactions (buy and sells) for each holding held within the portfolio over the period. The tables exclude any non-equity holdings such as ETFs and any transfers from the combination with Witan.

    Even so, in the short run, market sentiment can have a larger impact on share prices than fundamentals. When we break down the portfolio performance against the Index into fundamentals and sentiment, the portfolio’s strong absolute performance has been mainly as a result of company fundamentals, whereas the Index’s absolute performance has been more driven by market sentiment.

    A full breakdown of the contributors to our Total Return in 2024 is shown in the following table.

    Contribution analysis

    Contribution to Return in 2024 %
    Benchmark Total Return 19.6
    Asset Allocation -1.1
    Stock Selection -5.3
    Gearing and Cash 0.6
    Investment Manager Impact -5.8
    Portfolio Total Return 13.8
    Share Buybacks 0.1
    Fees/Expenses -0.6
    Taxation -0.1
    Change in Fair Value of Debt 0.4
    Timing Differences -0.2
    NAV Total Return including Income, Debt at Fair Value 13.3
    Change in Discount 1.0
    Share Price Total Return 14.3

    Source: Performance and attribution data sourced from WTW, Juniper, MSCI Inc, FactSet and Morningstar as at 31 December 2024. Percentages may not add due to rounding.

    In the table below, we also list the top five contributors and detractors to portfolio performance during the year relative to the portfolio’s benchmark.

    Sands, Vulcan and Lyrical were the top performers

    As we would expect from such a diverse line up, performance among our Managers was mixed. This is by design, as we do not want the portfolio to be biased towards any one approach of investing, which might make returns vulnerable to a sudden switch from one style to another. This happened in 2022 when growth stocks began to suffer significantly as central banks raised interest rates to combat inflation. Sands Capital (‘Sands’), Vulcan Value Partners (‘Vulcan’), and Lyrical Asset Management (‘Lyrical’) were the top performers last year. Sands and Vulcan both benefitted from owning tech giants. Sands held NVIDIA while Vulcan held Amazon, but Sands’ largest contributor to relative performance was Axon Enterprise, an industrial business which makes tasers, body cameras and other software products. Its share price surged by 134% last year.

    Top five stock contributors to performance

    Stock Sector Country Average Active Weight (%) Total Return in Sterling (%) Attribution Effect Relative to Benchmark (%)
    Amazon Consumer Discretionary United States 1.0 47.0 0.2
    Axon Enterprise Industrials United States 0.2 134.2 0.2
    Salesforce Information Technology United States 0.4 29.8 0.2
    NRG Energy Utilities United States 0.4 80.6 0.2
    Nestle Consumer Staples Switzerland -0.4 -25.9 0.2

    Bottom five stock detractors to performance

    Stock Sector Country Average Active Weight (%) Total Return in Sterling (%) Attribution Effect Relative to Benchmark (%)
    NVIDIA Information Technology United States -1.8 176.1 -1.2
    Broadcom Information Technology United States -0.5 113.4 -0.6
    Novo Nordisk Health Care Denmark 0.8 -14.0 -0.6
    Tesla Consumer Discretionary United States -0.8 65.4 -0.6
    Apple Information Technology United States -3.9 32.8 -0.4

    Source: WTW.

    The tables above illustrate the top five contributors and detractors to returns relative to benchmark in 2024. It aims to explain at a stock level which companies drove relative returns. For example, the Alliance Witan portfolio was underweight relative to benchmark in NVIDIA, Broadcom, Tesla and Apple. These stocks had very strong returns, which hurt our portfolio’s relative performance. Conversely, not having an exposure to Nestle helped our relative performance given the stock was held in the benchmark and was down over the year. Our overweight position in Amazon, Axon Enterprise, Salesforce and NRG Energy contributed positively to relative returns given their strong performance. The average active weight is the arithmetic simple average weight of the stock in the portfolio minus the arithmetic simple average weight of the stock in the benchmark over the period.

    Vulcan’s largest contributor to our performance was KKR, the US-based private equity group, which returned 82%, prompting Vulcan to take profits. Its holding in Salesforce also did well, rising nearly 30%.

    Lyrical, a deep-value style investor, benefitted from owning several less talked-about US-based companies, which all rebounded from cheap valuations. These included NRG Energy, Ameriprise Financials and eBay.

    Of our Managers, the most notable laggard was Sustainable Growth Advisors (‘SGA’), which was disappointing given its focus on large cap growth stocks which, as a group, had the strongest price momentum. SGA suffered from holding Novo Nordisk, and two of its other positions, ICON and Synopsys also stood out as detractors. The recent poor performance of SGA follows a long period of outperformance, so returns since we appointed SGA remain strong. Value Managers Metropolis and ARGA Investment Management (‘ARGA’), the latter replacing Jupiter Asset Management (‘Jupiter’) in April, also struggled in the recent market environment, which has generally favoured growth managers.

    Portfolio changes: two new Managers added after combination with Witan

    As well as adding ARGA for Jupiter in the first half of the year, following Ben Whitmore’s decision to leave Jupiter to set up his own business, there were two further changes to the Manager line-up during the integration of Witan’s portfolio. Altogether, this contributed to an unusually high level of turnover of 98.5% of the portfolio in 2024. Both Alliance Trust and Witan already had GQG Partners (‘GQG’) and Veritas in common, which meant that there were some in-specie transfers of stocks. Additionally, the combination of Alliance and Witan presented us with an opportunity to introduce Jennison Associates (‘Jennison’) to the portfolio at a low cost.

    Based in the US, Jennison specialises in investing in innovative, fast-growing businesses. It had been one of Witan’s most successful managers and blending it with our other Managers increased the diversity of holdings in growth companies. We also took the opportunity to replace Black Creek Investment Management (‘Black Creek’) with EdgePoint Investment Group (‘EdgePoint’), while we were using a transition manager to keep costs down to a minimum.

    This change was prompted by succession planning at Black Creek. We had been monitoring Black Creek for some time due to the departure of a senior team member for health reasons and the uncertainty surrounding the timing of founder Bill Kanko’s retirement. With a similar investment style to Black Creek, EdgePoint seeks to buy good, undervalued businesses and hold them until the market fully realises their potential.

    Through the combination, we inherited a small number of investment trust and private equity fund holdings, representing less than 3% of the combined portfolio. These are specialist funds with portfolios focused on, among other things, early-stage life sciences, valuable intellectual property, innovative internet platforms and renewable infrastructure assets. Collective investments such as these are not normally part of our investment strategy. However, they are all trading at prices we believe are well below their intrinsic value, so rather than sell them at a loss, we will hold them until we can achieve attractive values.

    Beyond that, the combination did not lead to any change in our investment approach. We retain high conviction in our line-up of Managers and their ability to pick winning stocks, although we keep them under constant review for any red flags and have access to a deep bench of talented replacements should these be needed.

    Gearing: remaining cautious

    Our gross gearing stood at 8.4% at the end of 2024 (4.9% net of underlying Manager and central cash), slightly above the level of 7.1% at the start of the year, reflecting the improving outlook for equities as the year progressed. However, given the strong performance from equity markets, it is still towards the lower end of the typical range of 7.5 to 12.5%.

    Market outlook: multiple risks warrant diversification

    As 2025 began, the mood among investors was upbeat, with many hoping President Trump’s promises of deregulation and tax cuts would be supportive of equity markets. If returns can spread beyond a narrow group of highly valued US mega-cap technology stocks, it could provide firmer foundations for another good year for shares. The strong start to the year for European equities certainly offered hope for geographical diversification.

    However, on-off tariffs and geopolitical tensions loom large, creating considerable uncertainty. This was reflected in an increase in equity market volatility in February.

    In the first 2 months of 2025, the benchmark index rose by 2.2% suggesting that investors were still willing to look through some of the risks while forecast global growth and corporate earnings remain healthy. But confidence is fragile and, with valuations in the US still close to a record high despite February’s pullback, the market is vulnerable to setbacks.

    In this environment, we believe bottom-up stock picking, based on company fundamentals, should be a more reliable way to add value for shareholders in the long term than making bold, top-down market calls. So, we will continue to position the portfolio to maintain balanced regional, sector and style exposures, that are similar to the Index weightings by periodically adjusting Manager allocations. This should provide stability and reduce risk, while we rely on our Managers to add value by seeking out the best companies in each market segment.

    While retaining some exposure to US mega-cap tech stocks that may continue delivering attractive returns, our portfolio is not reliant on them. It also contains many stocks that have remained in the shadows but have been performing well operationally and have excellent prospects not yet reflected in their share prices.

    Hidden gems: stock picks with high potential

    We asked our eleven Stock Pickers for examples of strong but underappreciated companies in the portfolio

    Lyrical highlighted five of its US holdings that have underperformed the S&P 500 Index since the start of 2024 but, at the same time, have grown their forecast earnings per share by more than the Index. These are healthcare providers Cigna and HCA, WEX and Global Payments, which both provide business-to-business payment technology, and Gen Digital, which is a leading provider of cyber security and identity protection.

    “Interestingly, even on this list there is inconsistency by the market,” says Lyrical. “Cigna has the worst stock performance, but the second-best earnings per share (‘EPS’) growth. Gen Digital has the slowest EPS growth in the group, but the best performance”.

    ARGA cited Accor, the global hotel business, which has transitioned to an “asset light” business model by selling most of its hotels, while maintaining the lucrative franchise and management agreements attached to these properties. While Sands Capital sees potential in the share prices of Sika, a maintenance and building refurbishment specialist.

    “Investment results have been weak despite solid fundamental results,” says Sands. “We believe that investors have focused on slower than historical organic growth, caused by several factors, including the real estate crisis in China, slowdown in electric vehicle production, and a pause in green building incentives.”

    Sands Capital also mentioned Roper Technologies, a diversified industrial technology company, and Keyence, a leading designer of high-end factory automation based in Japan, as attractive businesses with share price appreciation potential.

    Vulcan highlighted CoStar Group, an information provider to the commercial and residential real estate industries, and Everest Group, a global insurance and reinsurance business, while GQG mentioned the UK-based pharmaceutical company AstraZeneca, the Brazil-based oil and gas company Petrobras, Bank Mandiri in Indonesia, and the Indian tobacco company ITC.

    SGA backed Danaher, the US industrial group, Intuit, which provides do-it-yourself accounting software for small businesses, and HDFC Bank in India. Jennison highlighted Reddit, the online social media platform.

    “Reddit is targeting 49% growth in the third quarter of 2024 and consensus is at 41% in Q4, but then market estimates are fading down to around 20% in 2025, which we think is overly conservative and creates an opportunity for investment today.”

    Veritas’s nominations for underappreciated businesses were Amadeus, the Spanish software company focusing on air travel, The Cooper Companies, which makes contact lenses, and Thermo Fisher Scientific, the world’s largest scientific equipment provider.

    Japan specialist Dalton’s best stocks included Bandai Namco, a multinational that publishes video games and makes toys, Shimano, the bicycle equipment manufacturer, and Rinnai, one of the global leaders in water heaters. Metropolis highlighted Andritz, the Austrian headquartered business supplying industrial equipment to the pulp and paper, metals and hydropower industries, Crown Holdings, which makes aluminium drinks cans, and Admiral, the UK insurer.

    Finally, EdgePoint, the newest addition to our Manager line-up, pointed to Dayforce, a global human resources software company, Nippon Paints Holdings in Japan, Franco-Nevada, a gold-focused royalty company in Canada, and Qualcomm, which invented significant pieces of the underlying technology required for mobile phones.

    “The market looks at Qualcomm as a handset supplier and the stock moves in relation to expected handset sales over the following quarters,” says EdgePoint. “We consider Qualcomm to be one of the world’s leading designers of energy-efficient processors at a point in time when demand for energy-efficient processing is growing rapidly across a wide range of industries. Some of the major opportunities for Qualcomm over the next 5 years include artificial intelligence, automobiles, personal computers and smartphones.”

    Altogether, these fundamentally strong businesses combine with others to create a robust, multi-manager portfolio that offers attractive long-term growth with lower risk than a single manager strategy, and therefore a more comfortable ride through the ups and downs of the market. Such companies may have remained below the radar in 2024, when investors became giddy with the stellar returns from the US technology shares, but we look forward to their attributes receiving the recognition from the market that they deserve.

    Craig Baker, Stuart Gray, Mark Davis
    Willis Towers Watson
    Investment Manager

    The securities referred to above represent the views of the underlying managers and are not stock recommendations.

    Summary of Portfolio
    As at 31 December 2024

    A full list of the Company’s Investment Portfolio can be found on the Company’s website, www.alliancewitan.com

    Top 20 holdings

    Name £m %
    Microsoft 236.3 4.3
    Amazon 197.4 3.6
    Visa 156.2 2.8
    UnitedHealth Group 116.4 2.1
    Alphabet 107.7 1.9
    Diageo 92.4 1.7
    Meta 88.6 1.6
    NVIDIA 82.7 1.5
    Aon 75.1 1.4
    Novo Nordisk 73.1 1.3
    Netflix 70.9 1.3
    Mastercard 70.7 1.3
    Eli Lilly 69.9 1.3
    Salesforce 61.5 1.1
    HDFC Bank 58.2 1.1
    Safran 53.3 1.0
    Taiwan Semiconductor 49.9 0.9
    Petrobras 48.1 0.9
    State Street 48.0 0.9
    Philip Morris 47.6 0.9

    The 20 largest stock positions, given as a percentage of the total assets. Each Stock Picker selects up to 20 stocks.*
    Top 20 holdings 32.9%
    Top 10 holdings 22.2%

    * Apart from GQG Partners, which also manages a dedicated emerging markets mandate with up to 60 stocks.

    Dividend

    We have paid our shareholders a rising dividend for 58 consecutive years. Providing that level of reliability is something of which we are extremely proud. We carefully manage the Company’s dividend. For instance, should there be a year in which income is unexpectedly high, we may retain some of that income to help fund future dividends. Due to our steady approach, the Company has received a ‘Dividend Hero’ investment company award from the Association of Investment Companies (‘AIC’).

    Our dividend policy

    Subject to market conditions and the Company’s performance, financial position and outlook, the Board will seek to pay a dividend that increases year on year. The Company expects to pay four interim dividends per year, on or around the last day of June, September, December and March, and will not, generally, pay a final dividend for a particular financial year.

    While shareholders are not asked to approve a final dividend, given the timing of the payment of the quarterly payments, each year they are given the opportunity to share their views when they are asked to approve the Company’s Dividend Policy.

    Fourth interim dividend

    As previously announced, a fourth interim dividend of 6.73p per ordinary share will be paid on 31 March 2025 to those shareholders who were on the register at close of business on 28 February 2025.

    Increased dividend

    The Company has increased its total dividend for the year ended 31 December 2024 to 26.7p per ordinary share (2023: 25.2p), a 6.0% increase on the previous year.

    Dividend 2024 (p) 2023 (p) % increase
    1st Interim 6.62 6.18 7.1
    2nd Interim 6.62 6.34 4.4
    3rd Interim 6.73 6.34 6.2
    4th Interim 6.73 6.34 6.2

    Reserves

    It is the Board’s intention to utilise distributable reserves as well as portfolio income to fund dividend payments. Further details of the dividend payments for the year to 31 December 2024 and information on distributable reserves can be found in notes 7 and 2(b)(x) of the Financial Statements, respectively.

    Ongoing Charges and Discount

    Ongoing charges1

    The Company’s ongoing charges ratio (‘OCR’) decreased to 0.56% (including the impact of the investment management fee waiver) (2023: 0.62%). Total administrative expenses were £3.9m (2023: £2.9m) and investment management expenses were £18.4m (2023: £16.3m). Further details of the Company’s expenses are provided in note 4 of the Financial Statements on page 90 of the Annual Report. The Company’s costs remain competitive for an actively managed multi-manager global equity strategy.

    Maintaining a stable discount1

    One of the Company’s strategic objectives is to maintain a stable share price discount to NAV. The Company has the authority to buy back its own shares in the market if the discount is widening and to hold these shares in Treasury.

    During the year under review, the Company’s share price traded at an average discount of 4.7% (2023: 6.0%). As at 31 December 2024, the Company’s share price discount was 4.7% (2023: 5.4%). The average discount (unweighted) for the AIC Global Sector was 7.9%.

    Share issuance and buybacks

    As a result of the combination with Witan, 120,949,382 new ordinary shares were issued for assets valued at £1.5bn implying an effective issue price of £12.7459246 per share.

    The Company bought back 1.2%* (2023: 3.0%) of its issued share capital during the year, purchasing 4,722,000 shares which were placed in Treasury. The total cost of the share buybacks was £57.0m (2023: £86.6m). The weighted average discount of shares bought back in the year was 5.7%. Share buybacks contributed a total of 0.1% to the Company’s NAV performance in the year.

    1. Alternative Performance Measure – see page 116 of the Annual Report for details.
    * Percentage based on the Company’s issued share capital (excluding shares held in Treasury) as at 31 December 2024.

    What We Do

    How WTW manages the portfolio

    WTW as Investment Manager has overall responsibility for managing the Company’s portfolio. It is the Investment Manager’s job to select a diverse team of expert Stock Pickers, each of whom invest in a customised selection of 10-20 of their ‘best ideas’. WTW then allocates capital to them, relative to the risks the Stock Picker represents. For example, small-cap stocks are typically more risky than large-cap stocks, so on average a small-cap specialist would tend to receive less capital than a Stock Picker who focuses on large-cap stocks. However, the allocations do not remain static; WTW keeps them under constant review and varies them over time according to market conditions, with the goal of keeping our exposures to different parts of global stocks markets well balanced.

    Stock Pickers are encouraged to ignore the benchmark and only buy a small number of stocks in which they have strong conviction, while WTW manages risk through the Stock Picker allocations. On their own, each of the Stock Picker’s high-conviction mandates has the potential to perform well. This is supported by WTW’s experience of managing high-conviction portfolios and academic evidence1. But concentrated selections of stocks can be volatile and risky, so WTW mitigates these dangers by blending Stock Pickers with complementary investment approaches or styles, which can be expected to perform differently in different market conditions. This smooths out the peaks and troughs of performance associated with concentrated single-manager strategies.

    Several of the Stock Pickers in the current portfolio have been with the Investment Manager since inception of the multi-manager strategy, though it does actively monitor and rearrange the line-up where necessary.

    WTW invests a lot of time and effort on identifying skilled Stock Pickers for the Company’s portfolio, undertaking extensive qualitative and quantitative analysis. This due diligence process focuses on:

    • The investment processes, resources and decision-making that make up the Stock Picker’s competitive advantage;
    • The culture and alignment of the organisation that leads to sustainability of that competitive advantage;
    • Their approach to responsible investment. WTW aims to appoint Stock Pickers who actively engage with the companies in which they invest and have an effective voting policy. When necessary, they challenge the Stock Pickers and guide them towards better practices; and
    • The operational infrastructure that minimises risk from a compliance, regulatory and operational perspective.

    1. Sebastian & Attaluri, Conviction in Equity Investing, The Journal of Portfolio Management, Summer 2014.

    The Investment Manager’s views are formed over extended periods from multiple interactions with the Managers, including regular meetings. They look beyond past performance numbers to try to understand the ‘competitive edge’. This involves examining and interrogating processes for selecting stocks, adherence to this process through different market conditions, team dynamics, training and experience. Performance track records are just a single data point, and, without the context of the additional information, they are unlikely to persuade WTW that a Stock Picker is skilled.

    Once selected, the Investment Manager tends to form long-term partnerships with the Stock Pickers, generally only taking them out of the portfolio if something fundamental changes, such as the departure of a key individual from the business or a change in business strategy or fortunes. With highly active, concentrated portfolios, periods of short-term underperformance are to be expected and are not a reason to doubt a Stock Picker if they are adhering to their philosophy and process. WTW does, however, keep a constant eye out for talent and may bring new Managers into the portfolio at the expense of an incumbent if they are a better fit.

    Responsible investment

    WTW believes that Environmental, Social and Governance (‘ESG’) factors have the potential to impact financial risk and return. As long-term investors, WTW aims to incorporate these factors into its investment process.

    As stewards of the Company’s assets, WTW seeks to integrate responsible investment into its process for managing the portfolio. ESG factors can influence returns, so these risk factors are taken into account in WTW’s investment processes, including assessing how Managers evaluate ESG risk in their decisions over what stocks to purchase. Climate change poses potential significant risks to investment returns from many companies, which is why both WTW and the Company have stated an intention to manage the assets with a goal of achieving Net Zero greenhouse gas emissions from the portfolio by 2050, with an interim intention of reducing portfolio emissions by approximately 50% by 2030, relative to 2019.

    In 2024, we saw an increase in the portfolio’s weighted average carbon intensity (which measures carbon emissions as a proportion of revenue) from 71.9tCO2e/$M sales to 117. 9tCO2e/$M sales. Over the year, some higher-emitting stocks came into the portfolio including, industrial company Alaska Air and materials company Alcoa Ord, and our allocation to the higher-emitting Utilities sector went up slightly with purchases of companies such as Southern Ord and American Electric Power. We are monitoring our progress against our Net Zero goal, and our Managers and EOS at Federated Hermes (‘EOS’) continue to engage with the companies in the portfolio on climate related issues.

    Progress towards Net Zero will not be linear. Emissions from the portfolio are dependent on holdings, which can change from year to year as WTW’s Stock Pickers seek value for investors. If companies are perceived as being at higher financial risk by being slow to adapt to a Net Zero world, we expect to use stewardship, such as voting and engagement, to encourage positive changes to business practices. WTW believes this is preferable to excluding companies from the portfolio, since exclusion merely passes the responsibility of ownership to other investors who may be less scrupulous about adherence to ESG standards or regulation.

    As well as engaging with companies on climate change, WTW’s Stock Pickers, together with stewardship provider EOS, focused on a wide range of other issues last year.

    Overall, EOS engaged with 97 companies in the portfolio on 515 issues and objectives throughout the year. Key areas of engagement included board effectiveness, climate change, human and labour rights and human capital, biodiversity, digital rights and AI. Of these engagements, the environmental category accounted for 29% of the total number of engagements, with 63% of environmental engagements relating to climate change. Meanwhile the Stock Pickers cast votes at 3,346 resolutions in 2024. Of these resolutions, they voted against company management on 386 and abstained from voting on 38 occasions.

    How We Manage Our Risks

    In order to monitor and manage risks facing the Company, the Board maintains and regularly reviews a risk register and heat map. The risk register details all principal and emerging risks thought to face the Company at any given time. The principal risks facing the Company, as determined by the Board, are Investment, Operational and Legal and Regulatory Non-Compliance.

    As part of its review process, the Board considers input on the principal and emerging risks facing the Company from its key service providers WTW and Juniper. Any risks and their associated risk ratings are then discussed, and the risk register and heat map updated accordingly, with additional measures put in place to monitor, manage and mitigate risks as required. During the period the Board carefully reviewed the risks associated with the implementation of the combination and the post transaction integration risks.

    Principal risks

    The principal risks facing the Company, how they have changed during the year and how the Board aims to monitor and manage these risks are detailed below.

    Risk and potential impact Risk rating How we monitor and manage the risk
    Market risk: loss on the portfolio in absolute terms, caused by economic and political events, interest rate movements and fluctuation in foreign exchange rates. Increased due to geopolitical and macro-economic uncertainty
    • The Board sets investment guidelines and the Investment Manager selects Stock Pickers and styles to provide diversification within the portfolio.
    • The Board receives regular updates from the Investment Manager and monitors adverse movements and impacts on the portfolio.
    • An explanation of the different components of market risk and how they are individually managed is contained in note 18 to the Financial Statements.
    Investment performance: relative underperformance makes the Company an unattractive investment proposition. Stable
    • The Company’s investment performance against its investment objective, relevant benchmark and closed and open ended peer group are reviewed and challenged where appropriate by the Board at every Board meeting.
    • The Board receives regular reporting from the Investment Manager to allow it to review the approach to ESG and climate risk factors embedded within the investment process from the Company’s perspective.
    Strategy and market rating: demand for the Company’s shares decreases due to changes in demand for the Company’s strategy or secular changes in investor demand. Stable
    • The Board regularly reviews the share register and receives feedback from the Investment Manager and broker on all marketing and investor relations and shareholder meetings, to keep informed of investor sentiment and how the Company is perceived in the market.
    • The Board monitors the Company’s share price discount and, working with the broker undertakes periodic share buybacks as appropriate to meet its strategic objective of maintaining a stable discount.
    • The proposed combination with Witan and the benefits to ongoing investors in terms of scale and investor proposition were reviewed and thoroughly considered to ensure the enlarged Company would be an attractive proposition for both current and prospective shareholders.
    Capital structure and financial risk: inappropriate capital or gearing structure may result in losses for the Company. Stable
    • The Board receives regular updates on the capital structure of the Company including share capital, borrowings, structure of reserves, compliance with ongoing covenants and shareholder authorities, to allow ongoing monitoring of the appropriate structure.
    • The Board reviews and manages the borrowing limits under which the Investment Manager operates. As part of the Witan combination, additional borrowing was novated to the Company. These additional facilities provide an increased blend of interest rates and maturity dates.
    • Shareholder authority is sought annually in relation to share issuance and buybacks to facilitate ongoing management of the share capital.
    Operational
    All of the Company’s operations are outsourced to third party service providers. Any failure in the operational controls of the Company’s service providers could result in financial, legal or regulatory and reputational damage for the Company.
    Operational risks include cyber security, IT systems failure, inadequacy of oversight and control, climate risk and ineffective disaster recovery planning.
    Stable
    • The Board monitors the services provided by the key services suppliers and formally reviews the performance of each on an annual basis, including the review of audited internal control reports where appropriate. No material issues were raised as part of the evaluation process in 2024.
    • Cyber security continues to be a key focus for the Board. Reports on the cyber security, IT testing environment and disaster recovery testing of each key service provider are reviewed by the Board annually.
    • Any breaches in controls which have resulted in errors or incidents are required to be immediately notified to the Board along with proposed remediation actions.
    Legal and regulatory
    Failure to adhere to all legal and regulatory requirements could lead to financial and legal penalties, reputational damage and potential loss of investment trust status. Stable
    • The Board has contracted with its key service suppliers, including the Investment Manager and Juniper, in relation to its ongoing legal and regulatory compliance. The Board receives quarterly reports from each supplier to monitor ongoing compliance. The Company has complied with all legal and regulatory requirements in 2024.
    • Any breaches in controls which have resulted in errors or incidents are required to be immediately notified to the Board, along with proposed remediation actions.
    • The review of the Annual Report by the independent auditors provides additional assurance that the Company has met all legal and regulatory requirements in respect of those disclosures.

    Emerging risks

    Emerging risks are typified by having a high degree of uncertainty and may result from sudden events, new potential trends or changing specific risks where the impact and probable effect is hard to assess. As the assessment becomes clearer, the risk may be added to the risk matrix of ‘known’ risks.

    The Board is currently monitoring a number of emerging risks: geopolitical tension continues to be an emerging risk for the Company due to ongoing conflicts across the world. Along with increased populism and nationalism, these risks may impact individual economies and global markets. Although covered in the operational risk section above, the Board recognises the increased risk that cybercrime and the misuse of AI poses to the Company.

    Geopolitical events such as the conflicts in the Middle East region, coupled with the potential breakdown of post war alliances and potential new trade tariffs and changes to US economic and international policies introduced by President Trump, could bring uncertainty and fragility to capital markets in 2025, including persistent or reacceleration of inflationary pressures.

    Stakeholder Engagement – Section 172 Statement

    The Directors have a number of obligations including those under section 172 of the Companies Act 2006. These obligations relate to how the Board takes account of various factors in making its decisions – including the impact of its decisions on key stakeholders. The Board is focused on the Company’s performance and its responsibilities to stakeholders, corporate culture and diversity, as well as its contributions to wider society, and it takes account of stakeholder interests when making decisions on behalf of the Company.

    As an externally-managed investment trust, the Board considers the Company’s key stakeholders to be existing and potential new shareholders and its service providers.

    Full details on the primary ways in which the Board engaged with the Company’s key stakeholders can be found on pages 30 to 35 of the Annual Report.

    Dean Buckley
    Chair
    6 March 2025

    Viability and Going Concern Statements

    Viability Statement

    The Board has assessed the prospects and viability of the Company beyond the 12 months required by the Going Concern accounting provisions.

    The Board considered the current position of the Company and its prospects, strategy and planning process as well as its principal and emerging risks in the current, medium and long term, as set out on pages 27 to 29 of the Annual Report. After the year-end but prior to approval of these Accounts, the Board reviewed its performance against its strategic objectives and its management of the principal and emerging risks facing the Company.

    The Board received regular updates on performance and other factors that could impact on the viability of the Company.

    The Board has concluded that there is a reasonable expectation that the Company will be able to continue in operation and meet its liabilities as they fall due for at least the next five years; the Board expects this position to continue over many more years to come. The Company’s Investment Objective, which was approved by shareholders in April 2019, is to deliver a real return over the long term, through a combination of capital growth and a rising dividend, and the Board regards the Company’s shares as a long-term investment. The Board believes that a period of five years is considered a reasonable period for investment in equities and is appropriate for the composition of the Company’s portfolio.

    In arriving at this conclusion, the Board considered:

    • Financial strength: As at 31 December 2024 the Company had total assets of £5.6bn, with net gearing of 4.9% and gross gearing of 8.4%. At the year-end the Company had £182.7m of cash or cash equivalents.
    • Investment: The portfolio is invested in listed equities across the globe. The portfolio is structured for long-term performance; the Board considers five years as being an appropriate period over which to measure performance.
    • Liquidity: The Company is closed-ended, which means that there is no requirement to realise investments to allow shareholders to sell their shares. The Directors consider this structure supports the long-term viability and sustainability of the Company, and have assumed that shareholders will continue to be attracted to the closed-ended structure due to its liquidity benefit. During the year, WTW carried out a liquidity analysis and stress test which indicated that around 93% of the Company’s portfolio could be sold within a single day and a further 6% within 10 days, without materially influencing market pricing. WTW performs liquidity analysis and stress testing on the Company’s portfolio of investments on an ongoing basis under both current and stressed conditions. WTW remains comfortable with the liquidity of the portfolio under both of these market conditions. The Board would not expect this position to materially alter in the future.
    • Dividends: The Company has significant accumulated distributable reserves which together with investment income can be used to support payment of the Company’s dividend. The Board regularly reviews revenue forecasts and considers the long-term sustainability of dividends under a variety of different scenarios. The Company has sufficient funds to meet its Dividend Policy commitments.
    • Reserves: The Company has large reserves (at 31 December 2024 it had £3.7bn of distributable reserves and £1.5bn of other reserves).
    • Discount: The Company has no fixed discount control policy. The Company will continue to buy back shares when the Board considers it appropriate, to take advantage of any significant widening of the discount and to produce NAV accretion for shareholders.
    • Significant Risks: The Company has a risk and control framework which includes a number of triggers which, if breached, would alert the Board to any potential adverse scenarios. The Board has developed and reviewed various scenarios based on potentially adverse events as set out in note 18 on pages 100 to 107 of the Annual Report.
    • Borrowing: In consideration of the combination with Witan, the Company’s borrowing facilities were reviewed to ensure they remained appropriate. The Company’s available bank borrowing facilities were consequently increased by £50m; and £155m of fixed rate loan notes were novated from Witan as part of the combination. The Company’s weighted average borrowings costs have reduced by 0.3%. All borrowings are secured by floating charges over the assets of the Company. The Company comfortably meets its banking covenants.
    • Security: The Company retains title to all assets held by the Custodian which are subject to further safeguards imposed on the Depositary.
    • Operations: Throughout the year under review, the Company’s key service providers continued to operate in line with service level agreements with no significant errors or breaches having been recorded.

    Going Concern Statement

    In view of the conclusions drawn in the foregoing Viability Statements, which considered the resources of the Company over the next 12 months and beyond, the Directors believe that the Company has adequate financial resources to continue in existence for at least the period to 31 March 2026. Therefore, the Directors believe that it is appropriate to continue to adopt the Going Concern basis in preparing the financial statements.

    Directors’ Responsibilities

    The Directors are responsible for preparing the Annual Report and the Financial Statements in accordance with UK-adopted international accounting standards and applicable law and regulations.

    Company law requires the Directors to prepare Financial Statements for each financial year. Under that law the Directors are required to prepare the Financial Statements in accordance with UK-adopted international accounting standards. Under company law the Directors must not approve the Financial Statements unless they are satisfied that they give a true and fair view of the state of affairs of the Company and of the profit or loss for that period.

    In preparing these Financial Statements, the Directors are required to:

    • Select suitable accounting policies and then apply them consistently;
    • Make judgements and accounting estimates that are reasonable and prudent;
    • State whether they have been prepared in accordance with UK-adopted International Accounting Standards, subject to any material departures disclosed and explained in the Financial Statements;
    • Prepare the Financial Statements on the Going Concern basis unless it is inappropriate to presume that the Company will continue in business; and
    • Prepare a Directors’ Report, a Strategic Report and Directors’ Remuneration Report which comply with the requirements of the Companies Act 2006.

    The Directors are responsible for keeping adequate accounting records that are sufficient to show and explain the Company’s transactions, and disclose with reasonable accuracy at any time the financial position of the Company and enable them to ensure that the Financial Statements comply with the Companies Act 2006.

    They are also responsible for safeguarding the assets of the Company and hence for taking reasonable steps for the prevention and detection of fraud and other irregularities. The Directors are responsible for ensuring that the Annual Report and Financial Statements, taken as a whole, are fair, balanced and understandable and provides the information necessary for shareholders to assess the Company’s position, performance, business model and strategy.

    Website publication

    The Directors are responsible for ensuring the Annual Report and the Financial Statements are made available on a website. Financial Statements are published on the Company’s website in accordance with legislation in the United Kingdom governing the preparation and dissemination of Financial Statements, which may vary from legislation in other jurisdictions. The maintenance and integrity of the Company’s website is the responsibility of the Directors. The Directors’ responsibility also extends to the ongoing integrity of the Financial Statements contained therein.

    Report of Directors and Responsibility Statement

    The Report of the Directors on pages 36 to 69 of the Annual Report (other than pages 61 to 63 which form part of the Strategic Report) of the Annual Report and Accounts has been approved by the Board. The Directors have chosen to include information relating to future development of the Company and relationships with suppliers, customers and others, and their impact on the Board’s decisions on pages 30 to 35 of the Annual Report.

    Each of the Directors, who are listed on pages 37 to 40 of the Annual Report, confirm to the best of their knowledge that:

    • The Financial Statements, prepared in accordance with the applicable set of UK adopted International Accounting Standards, give a true and fair view of the assets, liabilities, financial position and profit or loss of the Company;
    • The Annual Report includes a fair view of the development and performance of the business and the position of the Company, together with a description of the principal risks and uncertainties that the Company faces; and
    • In the opinion of the Board, the Annual Report and Financial Statements taken as a whole, are fair, balanced and understandable and provides the information necessary to assess the Company’s position, performance, business model and strategy.

    On behalf of the Board

    Dean Buckley
    Chair
    6 March 2025
    Statement of Comprehensive Income for the year ended 31 December 2024
      Year to 31 December 2024 Year to 31 December 2023
      Revenue Capital Total Revenue Capital Total
    £000            
    Income         72,463 354 72,817 69,591 1,678 71,269
    Gains on investments held at fair value through profit or loss – 449,551 449,551 – 578,715 578,715
    Losses on derivatives – (206) (206) – – –
    Gains/(losses) on fair value of debt – 16,708 16,708 – (11,371) (11,371)
    Total 72,463 466,407 538,870 69,591 569,022 638,613
    Investment management fees (5,381) (13,058) (18,439) (5,074) (11,228) (16,302)
    Administrative expenses (3,661) (281) (3,942) (2,558) (344) (2,902)
    Finance costs (3,221) (9,662) (12,883) (2,380) (7,141) (9,521)
    Foreign exchange losses – (1,010) (1,010) – (3,737) (3,737)
    Profit before tax 60,200 442,396 502,596 59,579 546,572 606,151
    Taxation (6,545) (5,348) (11,893) (6,231) (251) (6,482)
    Profit for the year 53,655 437,048 490,703 53,348 546,321 599,669

    All profit for the year is attributable to equity holders.

           
             
    Earnings per share (pence per share) 17.30 140.95 158.25 18.55 189.98 208.53

    All revenue and capital items in the above statement derive from continuing operations.

    The ‘Total’ column of this statement is the profit and loss account of the Company and the ‘Revenue’ and ‘Capital’ columns represent supplementary information prepared under guidance issued by the Association of Investment Companies. The Company does not have any other comprehensive income and hence profit for the year, as disclosed above, is the same as the Company’s total comprehensive income.

    Statement of Changes in Equity for the year ended 31 December 2024
            Distributable reserves  
    £000 Share
    capital
    Share premium account Capital redemption reserve Realised capital reserve Unrealised capital reserve Revenue reserve Total distributable reserves Total equity
                     
    At 1 January 2023 7,314 – 11,684 2,669,933 103,754 102,334 2,876,021 2,895,019
    Total comprehensive income:                
    Profit for the year – – – 75,430 470,891 53,348 599,669 599,669
    Transactions with owners, recorded directly to equity:                
    Ordinary dividends paid – – – – – (71,378) (71,378) (71,378)
    Unclaimed dividends returned – – – – – 14 14 14
    Own shares purchased (208) – 208 (86,636) – – (86,636) (86,636)
    Balance at 31 December 2023 7,106 – 11,892 2,658,727 574,645 84,318 3,317,690 3,336,688

    Total comprehensive income:

                   
    Profit for the year – – – 458,122 (21,074) 53,655 490,703 490,703
    Transactions with owners, recorded directly to equity:                
    Issue of ordinary shares in respect of the combination with Witan 3,024 1,535,877 – – – – – 1,538,901
    Costs in relation to the combination – (4,947) – – – – – (4,947)
    Ordinary dividends paid – – – – – (82,414) (82,414) (82,414)
    Unclaimed dividends returned – – – – – 9 9 9
    Own shares purchased – – – (56,987) – – (56,987) (56,987)
    Balance at 31 December 2024 10,130 1,530,930 11,892 3,059,862 553,571 55,568 3,669,001 5,221,953

    The £553.6m (2023: £574.6m) of unrealised capital reserve arising on the revaluation of investments is subject to fair value movements and may not be readily realisable at short notice, as such it may not be entirely distributable. The unrealised capital reserve includes unrealised gains on borrowings of £22.8m (2023: £5.5m) and gains on unquoted investments of £3.5m (2023: £nil) which are not distributable.

    Balance Sheet as at 31 December 2024
      2024 2023
    £000    
    Non-current assets            
    Investments held at fair value through profit or loss 5,402,381 3,482,329
      5,402,381 3,482,329
    Current assets    
    Outstanding settlements and other receivables 11,282 9,321
    Cash and cash equivalents 182,725 84,974
      194,007 94,295
    Total assets 5,596,388 3,576,624
    Current liabilities    
    Outstanding settlements and other payables (13,057) (9,792)
    Bank loans (45,245) –
      (58,302) (9,792)
         
    Total assets less current liabilities 5,538,086 3,566,832
         
    Non-current liabilities    
    Fixed rate loan notes held at fair value (299,276) (215,144)
    Bank loans (15,000) (15,000)
    Deferred tax provision (1,857) –
      (316,133) (230,144)
    Net assets 5,221,953 3,336,688
         
    Equity    
    Share capital 10,130 7,106
    Share premium account 1,530,930 –
    Capital redemption reserve 11,892 11,892
    Capital reserve 3,613,433 3,233,372
    Revenue reserve 55,568 84,318
    Total equity 5,221,953 3,336,688
    All net assets are attributable to equity holders.
     
    Net asset value per ordinary share attributable to equity holders (£) £13.05 £11.75

    The Financial Statements were approved by the Board of Directors and authorised for issue on 6 March 2025.

    They were signed on its behalf by:

    Jo Dixon
    Chair of the Audit and Risk Committee

    Cash Flow Statement for the year ended 31 December 2024
      2024 2023
    £000    
    Cash flows from operating activities    
    Profit before tax 502,596 606,151
         
    Adjustments for:    
    Gains on investments (449,551) (578,715)
    Losses on derivatives 206 –
    (Gains)/losses on fair value of debt (16,708) 11,371
    Foreign exchange losses 1,010 3,737
    Finance costs 12,883 9,521
    Operating cash flows before movements in working capital 50,436 52,065
    (Increase)/decrease in receivables (2,274) 1,599
    Decrease in payables (43) (36)
    Net cash inflow from operating activities before tax 48,119 53,628
    Taxes paid (10,701) (6,654)
    Net cash inflow from operating activities 37,418 46,974
         
    Cash flows from investing activities    
    Proceeds on disposal of investments 4,697,547 1,600,165
    Purchases of investments (4,702,449) (1,489,643)
    Settlement of derivative financial instruments (206) –
    Net cash (outflow)/inflow from investing activities (5,108) 110,522
    Net cash inflow before financing 32,310 157,496
         
    Cash flows from financing activities    
    Dividends paid – equity (82,414) (71,378)
    Unclaimed dividends returned 9 14
    Net cash acquired following the combination with Witan 177,581 –
    Costs paid in relation to the combination with Witan (4,947) –
    Purchase of own shares (56,987) (88,060)
    Repayment of bank debt (59,000) (63,500)
    Drawdown of bank debt 104,874 15,000
    Issue of loan notes – 60,632
    Finance costs paid (12,033) (10,357)
    Net cash inflow/(outflow) from financing activities 67,083 (157,649)
         
    Net increase/(decrease) in cash and cash equivalents 99,393 (153)
    Cash and cash equivalents at the start of the year 84,974 88,864
    Effect of foreign exchange rate changes (1,642) (3,737)
    Cash and cash equivalents at end of the year 182,725 84,974

    The financial information set out above does not constitute the Company’s statutory Financial Statements for the years ended 31 December 2024 or 2023, but is derived from those Financial Statements. Statutory accounts for 2023 have been delivered to the Registrar of Companies and those for 2024 will be delivered following the Company’s Annual General Meeting. The auditors have reported on those accounts; their reports were unqualified, did not draw attention to any matters by way of emphasis without qualifying their report and did not contain statements under s498(2) or (3) Companies Act 2006.

    The same accounting policies, presentations and methods of computation are followed in these Financial Statements as were applied in the Company’s last annual audited Financial Statements, other than those stated in the Annual Report.

    Basis of accounting

    The Financial Statements have been prepared in accordance with UK-adopted international accounting standards (‘IASs’).

    The Financial Statements have been prepared on the historical cost basis, except that investments and fixed rate notes are stated at fair value through the profit and loss. The Association of Investment Companies (‘AIC’) issued a Statement of Recommended Practice: Financial Statements of Investment Companies (‘AIC SORP’) in July 2022. The Directors have sought to prepare the Financial Statements in accordance with the AIC SORP where the recommendations are consistent with International Financial Reporting Standards (‘IFRS’). The Company qualifies as an investment entity.

    1. Income    
    An analysis of the Company’s revenue is as follows:    
         
    £000 2024 2023
    Revenue:    
    Income from investments    
    Listed dividends – UK 10,125 12,836
    Listed dividends – Overseas 60,838 55,761
      70,963 68,597
    Other income    
    Bank interest 1,475 987
    Other income 25 7
      1,500 994
    Total allocated to revenue 72,463 69,591
         
    Capital:    
    Income from investments    
    Listed dividends – UK 23 –
    Listed dividends – Overseas 331 1,678
    Total allocated to capital 354 1,678
    Total income 72,817 71,269
    2. Dividends    
    Dividends paid during the year    
         
    £000 2024 2023
    2022 fourth interim dividend 6.00p per share – 17,498
    2023 first interim dividend 6.18p per share – 17,849
    2023 second interim dividend 6.34p per share – 18,028
    2023 third interim dividend 6.34p per share – 18,003
    2023 fourth interim dividend 6.34p per share 18,003 –
    2024 first interim dividend 6.62p per share 18,799 –
    2024 second interim dividend 6.62p per share 18,676 –
    2024 third interim dividend 6.73p per share 26,936 –
      82,414 71,378
         
    Dividends payable for the year

    We also set out below the total dividend payable in respect of the financial year, which is the basis on which the requirements of Section 1158/1159 of the Corporation Tax Act 2010 are considered.

    £000 2024 2023
    2023 first interim dividend 6.18p per share – 17,849
    2023 second interim dividend 6.34p per share – 18,028
    2023 third interim dividend 6.34p per share – 18,003
    2023 fourth interim dividend 6.34p per share – 18,003
    2024 first interim dividend 6.62p per share 18,799 –
    2024 second interim dividend 6.62p per share 18,676 –
    2024 third interim dividend 6.73p per share 26,936 –
    2024 fourth interim dividend 6.73p per share, payable 31 March 2025 26,933 –
      91,344 71,883
    3. Earnings per share
    The calculation of earnings per share is based on the following data:
     
      2024 2023
    £000 Revenue Capital Total Revenue Capital Total
    Ordinary shares            
    Earnings for the purpose of earnings per share being net profit attributable to equity holders 53,655 437,048 490,703 53,348 546,321 599,669
                 
    Number of shares            
    Weighted average number of ordinary shares in issue during the year   310,079,630   287,573,436

    The Company has no securities in issue that could dilute the return per ordinary share. Therefore the basic and diluted earnings per ordinary share are the same.

    4. Related party transactions

    There are amounts of £1,222 (2023: £1,222) and £34,225 (2023: £34,225) owed to AT2006 and The Second Alliance Trust Limited, respectively, at year-end.

    There are no other related parties other than those noted below.

    Transactions with key management personnel

    Details of the Non-Executive Directors are disclosed on pages 37 to 40 of the Annual Report.

    For the purpose of IAS 24 ‘Related Party Disclosures’, key management personnel comprised the Non-Executive Directors of the Company.

    Details of remuneration are disclosed in the Remuneration Report on pages 55 to 60 of the Annual Report.

    £000 2024 2023
    Total emoluments 337 350
         

    ANNUAL REPORT

    The Annual Report will be available in due course on the Company’s website www.alliancewitan.com. It will also be made available to the public at the Company’s registered office, River Court, 5 West Victoria Dock Road, Dundee DD1 3JT and at the offices of the Company’s Registrar, Computershare Investor Services PLC, Edinburgh House, 4 North St Andrew Street, Edinburgh EH2 1HJ after publication.

    In addition to the full Annual Report, up-to-date performance data, details of new initiatives and other information about the Company can be found on the Company’s website.

    ANNUAL GENERAL MEETING

    This year’s AGM will be held on 1 May 2025 at 11.00 a.m. at the Apex City Quay Hotel & Spa, 1 West Victoria Dock Road, Dundee DD1 3JP.

    The Board remains committed to maintaining a physical AGM, with shareholders and Directors present in person. However, the AGM will also be streamed live to shareholders. A web link will be provided for those shareholders wishing to join the AGM via the live stream. Information on how to obtain the link will be published on the Company’s website in due course.

    The MIL Network –

    March 7, 2025
  • MIL-OSI NGOs: Three vaccinations that are critical to women’s health

    Source: Médecins Sans Frontières –

    Hepatitis E, tetanus and hepatitis B all pose significant but under-reported threats to the health and lives of women and girls, especially in low-income countries with limited access to healthcare. This can also mean life or death for their babies.

    Nyakuola Nguot Gang lives with her extended family in Fangak county, South Sudan, where a deadly hepatitis E outbreak started in 2023 and continued through 2024.  

    “I almost lost my life while I was pregnant, in September,” says Nyakuola. “I thought it was only symptoms of my pregnancy, because my body was aching and I had a fever. I went for a blood test, and that’s when hepatitis E was discovered.”

    Some diseases have far greater negative consequences in women and girls, especially during pregnancy and childbirth. Hepatitis E, a water-borne infection that affects the liver, is one of them.  

    “A lot of people call it the Ebola for pregnant women, because you have a really high mortality rate in pregnant women, although we don’t really understand why it affects pregnant women so much,” says John Johnson, vaccination advisor for Médecins Sans Frontières (MSF). “The mortality rate is around 20 to 30 per cent in pregnancy.”  

    For pregnant women with hepatitis E, the risk of death is highest in the third trimester. 

    Pregnancy is also a critical time for vaccinating women and girls against tetanus if they haven’t been vaccinated before. A serious infection for people of any age, tetanus is deadly for newborns, but protecting the mother is lifesaving for her baby.  

    A third, lesser-known disease of concern is hepatitis B. If not prevented, it has lifelong, and life-limiting, consequences.  

    Both hepatitis B and tetanus pose significant health threats for victims and survivors of sexual violence, who are many times more likely than men to be women and girls.

    The good news is that there are vaccines available, but the reality is that they’re not reaching everyone who needs them, especially the women and girls who are most at risk.

    A groundbreaking vaccination campaign in South Sudan 

    Hepatitis E is the most common cause of acute viral hepatitis, linked to approximately 20 million infections and 70,000 deaths per year. This under-recognised disease predominantly affects people experiencing poverty or disadvantage – and is especially dangerous for pregnant women. It is transmitted through faecal contamination of food and water. Large-scale outbreaks typically occur when water and sanitation conditions are inadequate.

    There is only one vaccine available, HEV 239, developed in China. MSF first piloted its use in an epidemic in Bentiu, South Sudan, in 2022, and through subsequent research has generated strong evidence of its safety and effectiveness.

    Fangak county is one of the most remote and difficult to access areas of South Sudan. With the area inundated by recurrent floods in recent years, its people have had to learn to survive in a changing environment.  

    An MSF vaccinator administers the hepatitis E vaccine to a woman in Hai Matar, Fangak County, in the first round of the campaign. South Sudan, December 2023.
    Gale Julius Dada/MSF

    “We are surrounded by water in all aspects,” says Fangak resident Bhan Gutjiath Wal. “You go to the market, you go through water. You stay at home, there is water too.”    

    But in September 2023, these conditions led to an outbreak of hepatitis E. Within two months, MSF launched only the second vaccination campaign in the world reacting to an active hepatitis E outbreak, and the first-ever during the acute stage of an outbreak in such remote and hard-to-reach communities. This joint undertaking with the Ministry of Health eventually spanned almost a year.

    “It was a personal decision to get vaccinated,” says Nyakuola. “Those who have witnessed people who have been vaccinated and live have made the decision to also get the vaccine.”

    Sharing lifesaving protection against tetanus between mother and baby 

    “Babies, especially in what we call the neonatal period, in their first 28 days – that is when they’re most susceptible to death from certain diseases and infections,” says Isabella Mayes, midwifery activity manager in MSF’s Old Fangak project. “So providing mothers with vaccinations gives their babies a little bit of protection until they can receive their vaccine later in life.”  

    If a woman is vaccinated against tetanus before she gives birth, lifesaving antibodies will transfer through the placenta into the baby’s blood.

    The bacteria that causes tetanus is widespread in the environment. The risk to newborns occurs when the cut umbilical cord is infected, usually due to unsterile tools or conditions.

    Isabella Mayes, midwifery activity manager, performs an ultrasound on a pregnant woman in Fangak county. South Sudan, January 2025.
    Paula Casado Aguirregabiria/MSF

    Known also as lockjaw, tetanus limits a baby’s ability to feed. The rigidity spreads through the whole body, and the baby’s muscles spasm uncontrollably. A baby will need intensive nursing care and isolation in a dark and quiet room to prevent reactive spasms, hospitalised for up to a month. Untreated, some 90 per cent of affected newborns will die.

    An estimated 24,000 newborns died of tetanus in 2021, according to the most recent global data available. While this figure represents a gradual decline over time, it tells us that women and girls continue to miss out on vital vaccinations, antenatal care and safe delivery care, especially in low-income countries.  

    Access to healthcare in South Sudan is extremely limited. MSF’s hospital in Old Fangak is the only facility of its kind providing care to the 20,000 people in the immediate vicinity, as well as in villages only reachable hours away by boat. This includes maternal immunisation as part of antenatal care. 

    Timely protection for victims and survivors of sexual violence

    The value of post-exposure vaccination is highlighted in care for sexual violence. A victim/survivor can be protected against both tetanus and hepatitis B after an assault or rape, but the window of opportunity to kickstart immunity is only 72 hours.

    “We [vaccinate] every patient that had any wounds,” says Renda Kella Dhol, a clinical officer in MSF’s team in Old Fangak. “We just do it immediately to prevent the disease, because [tetanus] is really very serious.”

    Hepatitis B is often transmitted through sexual contact. It is up to 100 times more infectious than HIV.  

    A woman walks in front of the entrance of the MSF hospital in Old Fangak, Jonglei State. South Sudan, December 2023.
    Gale Julius Dada/MSF

    “We don’t know the status of the perpetrator,” says Dhol. “That’s why we provide hepatitis B [vaccine] to prevent the patient from being infected by hepatitis B.”

    Hepatitis B virus often causes a long-term infection. It is a major public health problem, with an estimated 254 million people chronically infected and 1.1 million deaths worldwide in 2022 from hepatitis B-related liver disease, including liver cancer.  

    A woman can also unknowingly pass it on during childbirth to her baby, who will also need vaccination to avoid a 90 per cent likelihood of death.

    To raise awareness about sexual violence and the medical and psychological care available, MSF conducts health promotion in schools and other places where people gather, among community leaders and with the police.  

    Dhol acknowledges people are afraid of discussing the topic of sexual violence, something our teams try to dispel.  

    “We told them in song: Don’t be afraid. We are here for you. We are going to support [you]. It will never be [revealed] to everybody,” says Dhol. “But we need the right for you to have the medication and the treatment to prevent anything that might have happened during this, because it’s not your fault, and it’s happening everywhere in the world.”

    You could also be interested in

     

    South Sudan

    MSF strongly condemns armed attack on our healthcare workers in Nasir county

    Press Release 16 Jan 2025

     

    South Sudan

    South Sudan receives thousands of displaced and injured people fleeing intensified war in Sudan

    Press Release 20 Dec 2024

     

    Haiti

    In Haiti, escalating violence increases displacement and basic needs

    Project Update 6 Mar 2025

    MIL OSI NGO –

    March 7, 2025
  • MIL-Evening Report: ‘Don’t be that idiot’: surfing in a cyclone could cost you $16,000 or your life

    Source: The Conversation (Au and NZ) – By Amy Peden, NHMRC Research Fellow, School of Population Health & co-founder UNSW Beach Safety Research Group, UNSW Sydney

    Social media is awash with images of surfers chasing waves as Cyclone Alfred whips up seas off Australia’s east coast.

    Queensland Premier David Crisafulli has branded beachgoers as “idiots”. On Friday morning, he said those going to the beach as the cyclone approaches put themselves and emergency services at risk, adding:

    I plead to the people who might think that now is a great time to go out on the surf – it’s not. It’s not just for you I’m concerned, but for the innocent person who has to go in after you.

    Sightseers have been caught in storm surges, and rescuers have been forced into the surf to help others. Up and down the coast, beaches are closed.

    In Queensland, surfers have been warned they may face fines up to $16,000 for reckless behaviour.

    Despite all this, surfers and others continue to enter the water. It’s important to ask why – and what will it take to get them to stop?

    Only a surfer knows the feeling

    I research injury prevention with a focus on drowning and safety in the water. As cofounder of the UNSW Beach Safety Research Group, I have also led research into surfing.

    Surfers frequently chase waves in big surf. Research by my colleagues and I shows under normal conditions, surfers have a lower risk of dying during this activity than people taking part in other water-related activities such as swimming, wading, snorkelling and scuba diving.

    Although drowning is the leading cause of death while surfing, other severe injuries are relatively rare.

    Of course, injuries can occur. These include cervical spine fractures and other spinal cord injuries, head injuries and lacerations. These can be due to collision with a surfboard, a fin, or the ocean floor.

    Yet most surfers usually manage to avoid serious injury. Throw some mega waves into the mix, however, and things can turn deadly, fast.

    Research shows the risk of injury is almost 2.5 times higher when surfing in waves that were over head height or bigger, relative to other waves.

    Despite this, the lure of experiencing record-breaking waves can be hard to ignore.

    Research shows surfers are motivated by what’s known as “sensation seeking”. In other words, they are more likely to seek out intense experiences than those who participate in other, less extreme sports.

    The desire to “master nature” – or go into battle with a big wave and come out on top – has been documented in analyses of surfing motivation.

    For big wave surfers, the reward – and the risk – can can be even greater. The physical and mental preparation needed to take on such extremes are immense. Tragically, deaths do occur even when attempts are made to improve safety.

    This desire to take risks in the water contributes to the over-representation of males in drowning statistics.

    Such risk-taking behaviour often plays out on social media in aquatic locations and during extreme weather events.

    Other hazards, above and below the surface

    Beyond the waves, other hazards can cause increased risk of ill health and injury in stormy seas. Debris can increase the risk of blunt-force trauma, while fecal and other bacteria in stormwater can cause illness.

    Sea foam should not be considered harmless either, having been implicated in rescues and tragic cases of drowning in the past.

    In the long term, coastal erosion due to storm surges and powerful surf can create permanent changes, impacting infrastructure and changing the location and strength of rip currents – the number-one coastal drowning hazard.




    Read more:
    Can you spot a rip current? Test your knowledge with our interactive quiz


    Don’t be that idiot

    Having a cyclone this far south is a rare event, so it’s only natural for people to want to take a look. But sometimes there’s no safe viewing distance, and the safest place to be is at home.

    Unsafe behaviours in and around the surf are rife on social media. Mainstream media outlets often model unsafe behaviours too, with reporters delivering their “piece to camera” about the importance of staying away from the beach while themselves standing on the shore.

    Conditions are unpredictable. These include powerful waves and storm surges that can knock you off your feet and sweep you out to sea.

    Remember, emergency services are stretched right now. If you get into trouble in the surf, there may be no one to rescue you. Or untrained bystanders may come to your aid and get into trouble themselves.

    With numerous flood warnings in place and roads closed, as well as the risks present on the coast, it’s best to stay away from beaches, rock platforms and coastal areas for now. Hit the waves again when conditions have calmed down.




    Read more:
    Just 15 centimetres of water can float a car – but we are failing to educate drivers about the dangers of floodwaters


    Amy Peden receives funding from the Australian National Health and Medical Research Council, Surf Life Saving Australia and the NSW National Parks and Wildlife Service. She maintains an honorary (unpaid) affiliation with Royal Life Saving Society – Australia.

    – ref. ‘Don’t be that idiot’: surfing in a cyclone could cost you $16,000 or your life – https://theconversation.com/dont-be-that-idiot-surfing-in-a-cyclone-could-cost-you-16-000-or-your-life-251706

    MIL OSI Analysis – EveningReport.nz –

    March 7, 2025
  • MIL-OSI USA: Murkowski Questions FDA Nominee

    US Senate News:

    Source: United States Senator for Alaska Lisa Murkowski
    03.06.25
    Washington, DC – U.S. Senator Lisa Murkowski (R-Alaska) today questioned the President’s nominee to be Commissioner of the Food and Drug Administration (FDA), Martin Makary, during his appearance before the Health, Education, Labor, and Pensions (HELP) Committee. Murkowski raised the FDA’s handling of the Vaccine Advisory Committee, the handling of clinical trials for rare diseases, and funding for state and local governments to conduct food safety inspections.
    Full Transcript:
    Senator Murkowski: Doctor, welcome, it was a good conversation that we had, and I appreciated that. I thank you for the encourage to read that provision in your book, it was great airplane reading for me.
    Dr. Makary: Thank you, Senator.
    Senator Murkowski: I also want to thank you for the assurance you gave to Senator Collins regarding the Vaccine Advisory Committee, and ensuring there would be meetings going forward. I think for several of us who had I thought good substantive conversations with Secretary Kennedy, we had received assurances about things like the vaccination committee. So, we’re making sure again that important input goes forward is important to many of us, so I appreciate that.
    I wanted to talk to you this morning about an issue we discussed in my office, and that is with regards to ALS. The FDA’s accelerated approval pathway has really been important, and I think very promising for treatments for ALS and some other rare diseases. You have advocated for using common sense alongside science in regulatory decisions. So, very briefly, how do we define common sense here as it applies to the regulatory decisions of the FDA. How do we make sure that ALS patients who are looking at a very, very limited time frame, they can’t wait for the traditional approval process, there are some emerging measures using digital technologies, is this in your realm of common sense? Give me a little bit of insight here on how you would like to proceed on these approval pathways.
    Dr. Makary. Thank you, Senator. I very much enjoyed our time together, and talking through a bunch of these issues. We have to customize the regulatory process to the condition that we’re trying to be able to offer hope, so, if a condition affects 19 people in the world as a partial triplication chromosome 15 disorder does, or a disease that affects 52 kids in the world, we cannot require two randomized control trials. We have to customize the regulatory process to what we’re trying to do if our goal is to try to provide safe and effective therapies. So, I do believe firmly in that approach, and I do think we can use some commons sense to ask some big questions we’ve never asked before at the FDA. Why does it take 10 years for a drug to get approved? Why does a college student who suffers from chronic abdominal pain for years, and we have no idea what’s going on, and they go to Italy for a summer and they are suddenly cured of their abdominal pain? Why does a peanut allergy medication that’s been safe with data for decades get approved in Europe before the United States when nearly 10% of our population has a food allergy? So, I do think there’s a lot of areas where we can ask, does a drug need to be prescription, when it could be over-the-counter, why are requiring continuous glucose monitors to have a Doctor’s prescription when it’s good for people to use these monitors and learn about what they’re eating. We don’t just want to limit continuous glucose monitoring to people with diabetes, we want to prevent diabetes when 30% of our nation’s children has diabetes or pre-diabetes or some form of early insulin resistance. Why are we holding these tools to help people, empower them about their health, until after they’re sick, same with continuous blood pressure monitoring.
    Senator Murkowski: Well, as you point out, why do we wait. We want to make sure that there is a level of safety, that’s the job there through the FDA. But, again, being able to accelerate these in ways that are meaningful, and to your point, that actually fit with the population that you’re speaking to. So know that I’m going to be pushing you on this, as well as many other advocates out there.
    Dr. Makary: Thank you.
    Senator Murkowski: I want to quickly ask you about food safety inspections. State and local governments conduct about 60% of food processing facility inspections, 90% of produce safety inspections, 100% of retail food inspections. What has happened is we have seen in the Biden Administration, FDA planning to cut funding for state and local food safety programs. This impacts us in the state of Alaska when it comes to our seafood industry, and in other areas. So, I’m looking for a commitment from you that under the Trump Administration, the FDA is going to maintain funding for these contracts with state and local governments. They’ve proven that it’s more cost effective, more efficient, and it also is what Congress has asked for. So I’d like to know that you’re going to be supportive in that regard to state and local governments.
    Dr. Makary: I’m happy to look at that with you, Senator.
    Senator Murkowski: Very good. Thank you, Mr. Chairman. 

    MIL OSI USA News –

    March 7, 2025
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